检索结果-南通市图书馆

A Near-Infrared Polymer Acceptor Enables over 15%Efficiency for All-Polymer Solar Cells

Chinese Journal of Polymer Science 2022年第8期40卷 877-888,I0007页

作者： Tao Wang Rui Sun Xin-Rong Yang Yao Wu Wei Wang Qian Li chun-feng zhang Jie Min The Institute for Advanced Studies Wuhan UniversityWuhan430072China National Laboratory of Solid State Microstructures School of Physicsand Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing210093China Beijing National Laboratory for Molecular Sciences Beijing100190China Key Laboratory of Materials Processing and Mold(Zhengzhou University) Ministry of EducationZhengzhou450002China

Finding effective molecular design strategies to enable efficient charge generation,high charge transport,and small energy loss is a longstanding challenge for developing high-performance all-polymer solar cells(all-PSCs).Here,we designed and synthesized a fused-aromatic-ring-constructed near-infrared(NIR)polymer acceptor(PA)PYT-Tz with fused-ring benzotriazole(BTz)-based A’-DAD-A’structure as electron-deficient-core,n-nonane as alkyl-side-chain and thiophene asπ-bridge,and achieved a power conversion efficiency(PCE)of 15.10%for the all-PSCs with PYT-Tz as acceptor and a wide-bandgap PBDB-T as donor.A control PA PYT reported by our lab recently was introduced for investigating the synergistic effect of the electron-deficient-core and alkyl-side-chain on the optoelectronic properties and photovoltaic performance of the n-type PAs.Compared with PYT,the designed PYT-Tz exhibits intense and red-shifted absorption,upshifted energy levels,high electron mobility and ordered molecular packing in the active layers,and,blended with PBDB-T,yields the efficient hole injection,ultrafast charge generation,and the decreased non-radiative recombination loss of 0.17 eV.Of note is that the PCE of 15.10%is one of the highest PCE values for an all-PSC reported to date.Our results indicate BTz-based fused-aromatic-ring-constructed PAs are promising NIR acceptors in the all-PSCs.

关键词： Benzotriazole-based A’-DAD-A’structure Near-infrared polymer acceptor High-performance all-polymer solar cells

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hsp90-associated DNA replication checkpoint protein and proteasome-subunit components are involved in the age-related macular degeneration

引用

Chinese Medical Journal 2021年第19期134卷 2322-2332页

作者： Chen Xing Xiao-feng Liu chun-feng zhang Liu Yang Department of Ophthalmology Peking University First HospitalBeijing 100034China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education) Hepatopancreatobiliary Surgery Department IPeking University Cancer Hospital&InstituteBeijing 100142China Department of Medical Genetics School of Basic Medical SciencesPeking University Health Science CenterBeijing 100191China

Background:Age-related macular degeneration(AMD)is the leading cause of vision loss worldwide.However,the mechanisms involved in the development and progression of AMD are poorly delineated.We aimed to explore the critical genes involved in the progression of AMD.Methods:The differentially expressed genes(DEGs)in AMD retinal pigment epithelial(RPE)/choroid tissues were identified using the microarray datasets GSE99248 and GSE125564,which were downloaded from the gene expression omnibus database.The overlapping DEGs from the two datasets were screened to identify DEG-related biological pathways using gene ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses.The hub genes were identified from these DEGs through protein-protein interaction network analyses.The expression levels of hub genes were evaluated by quantitative real-time polymerase chain reaction following the induction of senescence in ARPE-19 with FK866.Following the identification of AMD-related key genes,the potential small molecule compounds targeting the key genes were predicted by PharmacoDB.Finally,a microRNA-gene interaction network was constructed.Results:Microarray analyses identified 174 DEGs in the AMD RPE compared to the healthy RPE samples.These DEGs were primarily enriched in the pathways involved in the regulation of DNA replication,cell cycle,and proteasome-mediated protein polyubiquitination.Among the top ten hub genes,HSP90AA1,CHEK1,PSMA4,PSMD4,and PSMD8 were upregulated in the senescent ARPE-19 cells.Additionally,the drugs targeting HSP90AA1,CHEK1,and PSMA4 were identified.We hypothesize that Hsa-miR-16-5p might target four out of the five key DEGs in the AMD RPE.Conclusions:Based on our findings,HSP90AA1 is likely to be a central gene controlling the DNA replication and proteasome-mediated polyubiquitination during the RPE senescence observed in the progression of AMD.Targeting HSP90AA1,CHEK1,PSMA4,PSMD4,and/or PSMD8 genes through specific miRNAs or small molecules might potentially alleviate the progression of AMD

关键词： Age-related macular degeneration Retinal pigment epithelium Cell senescence HSP90AA1 DNA damage checkpoint Proteasomal subunit components

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

FAST Observations of an Extremely Active Episode of FRB 20201124A.Ⅱ.Energy Distribution

引用

Research in Astronomy and Astrophysics 2022年第12期22卷 70-80页

作者： Yong-Kun zhang Pei Wang Yi feng Bing zhang Di Li Chao-Wei Tsai Chen-Hui Niu Rui Luo Ju-Mei Yao Wei-Wei Zhu Jin-Lin Han Ke-Jia Lee De-Jiang Zhou Jia-Rui Niu Jin-Chen Jiang Wei-Yang Wang chun-feng zhang Heng Xu Bo-Jun Wang Jiang-Wei Xu National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Research Center for Intelligent Computing Platforms Zhejiang LaboratoryHangzhou 311100China Department of Physics and Astronomy University of NevadaLas VegasNV 89154USA Nevada Center for Astrophysics University of NevadaLas VegasNV 89154USA NAOC-UKZN Computational Astrophysics Centre University of KwaZulu-NatalDurban 4000South Africa CSIRO Space and Astronomy PO Box 76EppingNSW 1710Australia Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China Department of Astronomy Peking UniversityBeijing 100871China

We report the properties of more than 800 bursts detected from the repeating fast radio burst(FRB)source FRB20201124A with the Five-hundred-meter Aperture Spherical radio Telescope(FAST)during an extremely active episode on UTC 2021 September 25–28 in a series of four papers.In this second paper of the series,we study the energy distribution of 881 bursts(defined as significant signals separated by dips down to the noise level)detected in the first four days of our 19 hr observational campaign spanning 17 days.The event rate initially increased exponentially but the source activity stopped within 24 hr after the 4th day.The detection of 542 bursts in one hour during the fourth day marked the highest event rate detected from one single FRB source so far.The bursts have complex structures in the time-frequency space.We find a double-peak distribution of the waiting time,which can be modeled with two log-normal functions peaking at 51.22 ms and 10.05 s,respectively.Compared with the emission from a previous active episode of the source detected with FAST,the second distribution peak time is smaller,suggesting that this peak is defined by the activity level of the source.We calculate the isotropic energy of the bursts using both a partial bandwidth and a full bandwidth and find that the energy distribution is not significantly changed.We find that an exponentially connected broken-power law function can fit the cumulative burst energy distribution well,with the lower and higher-energy indices being-1.22±0.01 and-4.27±0.23,respectively.Assuming a radio radiative efficiency ofη_(r)=10^(-4),the total isotropic energy of the bursts released during the four days when the source was active is already 3.9×10^(46)erg,exceeding~23%of the available magnetar dipolar magnetic energy.This challenges the magnetar models which invoke an inefficient radio emission(e.g.,synchrotron maser models).

关键词： (stars:)pulsars:general stars:individual(FRB 20201124A) methods:data analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

间充质干细胞治疗肝纤维化的现况和前景（英文）

引用

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2016年第11期17卷 831-841页

作者： Yang GUO Bo CHEN Li-jun CHEN chun-feng zhang Charlie XIANG State Key Laboratory for Diagnosis and Treatment of Infectious Diseases and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases the First Affiliated Hospital School of Medicine Zhejiang University

许多慢性肝病发展到终末阶段形成肝纤维化进而转变成肝硬化,严重威胁人们的健康。目前临床治疗肝纤维化的有效方法是肝移植,但由于供体缺乏、免疫排斥和治疗费用昂贵等诸多缺陷,这种疗法并不是一种理想的治疗途径。近些年细胞治疗研究火... 详细信息

许多慢性肝病发展到终末阶段形成肝纤维化进而转变成肝硬化,严重威胁人们的健康。目前临床治疗肝纤维化的有效方法是肝移植,但由于供体缺乏、免疫排斥和治疗费用昂贵等诸多缺陷,这种疗法并不是一种理想的治疗途径。近些年细胞治疗研究火热,间充质干细胞作为一种来源广泛、可定向迁移和多向分化的治疗载体,在肝纤维化治疗上具有广阔的应用前景。本文对间充质干细胞治疗肝纤维化的现状进行归纳,并对其可行性、局限性及应用前景进行分析。

关键词：间充质干细胞肝纤维化细胞治疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Slight Structural Disorder in Bithiophene-based Random Terpolymers with Improved Power Conversion Efficiency for Polymer Solar Cells

引用

Chinese Journal of Polymer Science 2018年第10期36卷 1129-1138页

作者： Meng-Han Wang Zhong-Yuan Xue Zhi-Wei Wang Wei-Hua Ning Yu Zhong Ya-Nan Liu chun-feng zhang Sven Huettner You-Tian Tao Key Lab for Flexible Electronics &Institute of Advanced Materials Jiangsu National Synergistic Innovation Center for Advanced Materials (SICAM) Nanjing Tech University Nanjing 211816 China National Laboratory of Solid State Microstructures School of Physics and Collaborative Innovation Center of Advanced Microstructures Nanjing University Nanjing 210093 China Macromolecular Chemistry Ⅰ Universitat Bayreuth 30 Universitatsstr 95447 Bayreuth Germany

A series of random terpolymers P2-P5 were designed and synthesized by randomly embedding 5 mol%, 10 mol%, 15 mol% and 25 mol% feed ratios of low cost 2,2-bithiophene as the third monomer to the famous donor-acceptor （D-A） type copolymer PTBT-Th （P1）. All polymers showed similar molecular weight with number-average molecular weight （Mn） and weight-average molecular weight （Mw） in the range of （59-74） and （93-114） kg·mol-1, respectively, to ensure a fair comparison on the structure-property relationships. Compared with the control copolymer PTBT-Th, the random terpolymers exhibited enhanced absorption intensity in a wide range from 400 nm to 650 nm in both solution and film as well as in polymer/PC71BM blends. From grazing incident wide-angle X-ray diffraction （GIWAXS）, compared with the regularly alternated copolymer PTB7-Th, the random terpolymers demonstrated mild structural disorder with reduced （100） lamellar stacking and slightly weakened （010） π-π stacking for the polymers as well as slightly reduced PC71BM aggregation in polymer/PC71BM blends. However, the measured hole mobility for terpolymers （（1.20-3.73） × 10 -4 cm2·V-1·s-1） was evaluated to be comparable or even higher than 1.35 × 10 -4 cm2·V-1 ·s-1 of the alternative copolymer. Enhanced average power conversion efficiency （PCE） from 7.35% to 8.11% and 7.79% to 8.37% was observed in both conventional and inverted device architectures from copolymer P1 to terpolymers P4, while further increasing the 2,2-bithiophene feed ratio decreased the PCE.

关键词： Bithiophene-based random terpolymers Structural disorder Polymer solar cells Photovoltaic properties

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

FAST Observations of an Extremely Active Episode of FRB 20201124A.Ⅳ.Spin Period Search

引用

Research in Astronomy and Astrophysics 2022年第12期22卷 99-122页

作者： Jia-Rui Niu Wei-Wei Zhu Bing zhang Mao Yuan De-Jiang Zhou Yong-Kun zhang Jin-Chen Jiang J.L.Han Di Li Ke-Jia Lee Pei Wang Yi feng Dong-Zi Li Rui Luo Fa-Yin Wang Zi-Gao Dai Chen-Chen Miao Chen-Hui Niu Heng Xu chun-feng zhang Wei-Yang Wang Bo-Jun Wang Jiang-Wei Xu National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Institute for Frontier in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China Department of Physics and Astronomy University of NevadaLas VegasNV 89154USA Department of Astronomy Peking UniversityBeijing 100871China NAOC-UKZN Computational Astrophysics Centre University of KwaZulu-NatalDurban 4000South Africa Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China Research Center for Intelligent Computing Platforms Zhejiang LaboratoryHangzhou 311100China Cahill Center for Astronomy and Astrophysics MC 249-17 California Institute of TechnologyPasadena CA 91125USA CSIRO Space and Astronomy PO Box 76EppingNSW 1710Australia School of Astronomy and Space Science Nanjing UniversityNanjing 210093China Key Laboratory of Modern Astronomy and Astrophysics Nanjing UniversityMinistry of EducationNanjing 210093China Department of Astronomy University of Science and Technology of ChinaHefei 230026China

关键词： pulsars:general methods:observational radio continuum:general

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

FAST Observations of an Extremely Active Episode of FRB 20201124A.Ⅲ.Polarimetry

引用

Research in Astronomy and Astrophysics 2022年第12期22卷 81-98页

作者： Jin-Chen Jiang Wei-Yang Wang Heng Xu Jiang-Wei Xu chun-feng zhang Bo-Jun Wang De-Jiang Zhou Yong-Kun zhang Jia-Rui Niu Ke-Jia Lee Bing zhang Jin-Lin Han Di Li Wei-Wei Zhu Zi-Gao Dai Yi feng Wei-Cong Jing Dong-Zi Li Rui Luo Chen-Chen Miao Chen-Hui Niu Chao-Wei Tsai Fa-Yin Wang Pei Wang Ren-Xin Xu Yuan-Pei Yang Zong-Lin Yang Ju-Mei Yao Mao Yuan Department of Astronomy Peking UniversityBeijing 100871China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China School of Astronomy University of Chinese Academy of SciencesBeijing 100049China Department of Physics and Astronomy University of NevadaLas VegasNV 89154USA CAS Key Laboratory of FAST NAOCChinese Academy of SciencesBeijing 100101China Research Center for Intelligent Computing Platforms Zhejiang LaboratoryHangzhou 311100China NAOC-UKZN Computational Astrophysics Centre University of KwaZulu-NatalDurban 4000South Africa Department of Astronomy University of Science and Technology of ChinaHefei 230026China Cahill Center for Astronomy and Astrophysics MC 249-17California Institute of TechnologyPasadenaCA 91125USA CSIRO Space and Astronomy P.O.Box 76EppingNSW 1710Australia School of Astronomy and Space Science Nanjing UniversityNanjing 210093China Key Laboratory of Modern Astronomy and Astrophysics(Nanjing University) Ministry of EducationChina South-Western Institute For Astronomy Research Yunnan UniversityYunnan 650504China Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China

As the third paper in the multiple-part series,we report the statistical properties of radio bursts detected from the repeating fast radio burst(FRB)source FRB 20201124A with the Five-hundred-meter Aperture Spherical radio Telescope during an extremely active episode between the 25th and 28th of September 2021(UT).We focus on the polarization properties of536 bright bursts with S/N>50.We found that the Faraday rotation measures(RMs)monotonically dropped from-579to-605 rad m^(-2)in the 4 day window.The RM values were compatible with the values(-300 to-900 rad m^(-2))reported 4 months ago.However,the RM evolution rate in the current observation window was at least an order of magnitude smaller than the one(~500 rad m^(-2)day^(-1))previously reported during the rapid RM-variation phase,but is still higher than the one(≤1 rad m^(-2)day^(-1))during the later RM no-evolution phase.The bursts of FRB 20201124A were highly polarized with the total degree of polarization(circular plus linear)greater than 90%for more than 90%of all bursts.The distribution of linear polarization position angles(PAs),degree of linear polarization(L/I)and degree of circular polarization(V/I)can be characterized with unimodal distribution functions.During the observation window,the distributions became wider with time,i.e.,with larger scatter,but the centroids of the distribution functions remained nearly constant.For individual bursts,significant PA variations(confidence level 5σ)were observed in 33%of all bursts.The polarization of single pulses seems to follow certain complex trajectories on the Poincarésphere,which may shed light on the radiation mechanism at the source or the plasma properties along the path of FRB propagation.

关键词： (stars:)pulsars:general stars:magnetars radio continuum:general polarization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Numerical Analysis of Perforation during Hydraulic Fracture Initiation Based on Continuous-Discontinuous Element Method

引用

Computer Modeling in Engineering & Sciences 2024年第8期140卷 2103-2129页

作者： Rui zhang Lixiang Wang Jing Li chun feng Yiming zhang School of Civil and Transportation Engineering Hebei University of TechnologyTianjin300401China Key Laboratory for Mechanics in Fluid Solid Coupling Systems Institute of MechanicsChinese Academy of SciencesBeijing100190China School of Civil Engineering and Architecture Zhejiang Sci-Tech UniversityHangzhou310018China Jinyun Institute Zhejiang Sci-Tech UniversityLishui321400China

Perforation is a pivotal technique employed to establish main flow channels within the reservoir formation at the outset of hydraulic fracturing operations.Optimizing perforation designs is critical for augmenting the efficacy of hydraulic fracturing and boosting oil or gas production.In this study,we employ a hybrid finite-discrete element method,known as the continuous–discontinuous element method(CDEM),to simulate the initiation of post-perforation hydraulic fractures and to derive enhanced design parameters.The model incorporates the four most prevalent perforation geometries,as delineated in an engineering technical report.Real-world perforations deviate from the ideal cylindrical shape,exhibiting variable cross-sectional profiles that typically manifest as an initial constriction followed by an expansion,a feature consistent across all four perforation types.Our simulations take into account variations in perforation hole geometries,cross-sectional diameters,and perforation lengths.The findings show that perforations generated by the 39g DP3 HMX perforating bullet yield the lowest breakdown pressure,which inversely correlates with increases in sectional diameter and perforation length.Moreover,this study reveals the relationship between breakdown pressure and fracture degree,providing valuable insights for engineers and designers to refine perforation strategies.

关键词： Hydraulic fracturing real perforation shape breakdown pressure perforation layout design CDEM

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Role of autoimmunity in primary biliary cirrhosis

引用

World Journal of Gastroenterology 2012年第48期18卷 7141-7148页

作者： Tian-Yan Shi feng-chun zhang Department of Rheumatology and Clinical Immunology Peking Union Medical College HospitalChinese Academy of Medical Science

Primary biliary cirrhosis(PBC) is an autoimmune liver disease characterized by the presence of serum autoantibodies and chronic nonsuppurative destructive cholangitis.The pathogenesis of PBC involves environmental factors,genetic predisposition and loss of immune tolerance.In recent years,it has become univocally accepted that an inappropriately activated immune response is one of the most important factors in PBC.In this study,the role of autoimmunity in PBC is summarized and a feasible research orientation is recommended.

关键词：自身免疫性疾病肝硬化原发性胆汁遗传易感性 PBC 肝脏疾病自身抗体

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The role of innate immunity in diabetic nephropathy and their therapeutic consequences

引用

Journal of Pharmaceutical Analysis 2024年第1期14卷 39-51页

作者： Min Yang chun zhang Department of Nephrology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China

Diabetic nephropathy (DN) is an enduring condition that leads to inflammation and affects a substantial number of individuals with diabetes worldwide. A gradual reduction in glomerular filtration and emergence of proteins in the urine are typical aspects of DN, ultimately resulting in renal failure. Mounting evidence suggests that immunological and inflammatory factors are crucial for the development of DN. Therefore, the activation of innate immunity by resident renal and immune cells is critical for initiating and perpetuating inflammation. Toll-like receptors (TLRs) are an important group of receptors that identify patterns and activate immune responses and inflammation. Meanwhile, inflammatory responses in the liver, pancreatic islets, and kidneys involve inflammasomes and chemokines that generate pro-inflammatory cytokines. Moreover, the activation of the complement cascade can be triggered by glycated proteins. This review highlights recent findings elucidating how the innate immune system contributes to tissue fibrosis and organ dysfunction, ultimately leading to renal failure. This review also discusses innovative approaches that can be utilized to modulate the innate immune responses in DN for therapeutic purposes.

关键词： Innate immunity Diabetic nephropathy Inflammation Toll-like receptor Inflammasomes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：