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Histological and ultrastructural changes induced by selenium in early experimental gastric carcinogenesis

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World Journal of Gastroenterology 2005年第29期11卷 4457-4460页

作者： yan-Ping Su Jun-Min tang yan tang Hui-Ying Gao Department of Histology and Embryology Taishan Medical College Taian 271000 Shandong Province China Department of Histology and Embryology Peking University Health Science Center Beijing 100083 China

AIM： To investigate the effect and significance of selenium in early experimental gastric carcinogenesis. METHODS： Weaning male Wistar rats were divided randomly into normal control group, experiment control group, low selenium （2 mg/L） group and high selenium （4 mg/L） group. Wistar rat gastric carcinogenesis was induced by N-methyl-N-nitro-N-nitroso guanidine （MNNG）（20 mg/kg） gavage dally for 10 d. Na2SeO3 was given by piped drinking 1 wk prior to MNNG gavage. The rats were killed at the 43^rd wk. The surface characteristics of gastric mucosa were observed with naked eyes. Histopathologic changes of rat gastric mucosa were observed by HE staining and AB-PAS methods. The changes of cellular ultrastructure were observed under transmission electron microscope. Statistical analysis was carried out by SPSS. RESULTS： The incidence rate of gastric mucosa erosion, hemorrhage and intestinal metaplasia was 0, 45.5%, 66.7%, and 92.9%, respectively （92.9% vs 45.5%, P〈0.05） in the normal control group, experiment control group, low selenium group, and high selenium group. Leiomyoma formed in the process of inducement of rat gastric carcinoma. Dietary Na2SeO3 （2 and 4 mg/L） slightly increased the incidence rate of leiomyoma （0.23%, 46.6%, and 46.6%）. gastric mucosa did not change in the course of rat gastric carcinogenesis. Dietary Na2SeO3 by pipe drinking could expand the intracellular secretory canaliculus of parietal cells and increase the number of endocrine cells and lysosomes. CONCLUSION： Dietary Na2SeO3 by pipe drinking aggravates gastric erosion, hemorrhage and promotes intestinal metaplasia of gastric mucosa. The mechanism may be related with the function of parietal cells.

关键词： Selenium Ultrastructure Experimental gastric carcinogenesis

Study on photocatalytic activity of MoS2/ZnO composite in visible light

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Optoelectronics Letters 2020年第6期16卷 446-450页

作者： tang chun-mei ZHANG Hong-yan ZHANG Jun School of Physical Science and Technology Xinjiang UniversityUrumqi 830046China

A series of MoS_2/ZnO compound photocatalysts with different mass ratios were successfully prepared by hydrothermal method. The X-ray diffraction(XRD), X-ray photoelectron spectroscopy(XPS), scanning electron microscope(SEM) and UV-vis absorption were used to characterize the prepared MoS_2/ZnO photocatalysts. It was proved that the combination of Mo S2 and Zn O can increase the content of oxygen vacancies on surface of Zn O, thus improving the light absorption capacity in visible light region and reducing the band gap of Zn O. And the photocatalytic performance of Zn O was improved. Experimental results show that the MoS_2/ZnO(3 wt%) compound has the highest degradation rate for methylene blue(MB) under visible light, which means that it has the best photocatalytic activity among all the prepared samples.

关键词： XPS XRD Study on photocatalytic activity of MoS_2/ZnO composite in visible light ZnO

强迫症患者家庭教养方式和顺应性与强迫症状的关系

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中国心理卫生杂志 2025年第1期39卷 8-12页

作者：梁燕杨航怡黄悦琦唐文新江小英浙江大学医学院附属精神卫生中心/杭州市第七人民医院杭州310013 南方医科大学南方医院广州510515

目的:探究强迫症患者父母教养方式和家庭顺应性与强迫症状的关系。方法:在某医院门诊及住院部招募强迫症患者216例(轻度强迫症状59例,中度强迫症状121例,重度强迫症状36例),采用耶鲁-布朗强迫症量表(Y-BOCS)、父母教养方式评价量表(EMBU... 详细信息

目的:探究强迫症患者父母教养方式和家庭顺应性与强迫症状的关系。方法:在某医院门诊及住院部招募强迫症患者216例(轻度强迫症状59例,中度强迫症状121例,重度强迫症状36例),采用耶鲁-布朗强迫症量表(Y-BOCS)、父母教养方式评价量表(EMBU)、强迫症家庭顺应性行为量表患者版(FAS-PV)评估。结果:重度强迫症状者的父母积极教养得分最低,父母消极教养得分、FAS-PV总分最高(均P<0.01)。有序logistic回归分析显示,男性患者强迫症状程度更轻(OR=0.22);受教育年限越低、父母积极教养方式得分越低,强迫症状越重(OR=0.87、0.98、0.97);父亲消极教养方式得分越高、FAS-PV总分越高,强迫症状越重(OR=1.02、1.04)。结论:本研究提示强迫症状严重程度与父母教养方式及家庭顺应性有关。重度强迫症患者父母积极教养方式更少,父亲消极教养方式更多,家庭顺应性更高。

关键词：强迫症父母教养方式家庭顺应性

Synthesis and Properties of SEPS-g-PEO Copolymers with Varying Branch Lengths

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Chinese Journal of Polymer Science 2018年第8期36卷 934-942页

作者： Zhong-Fu Zhao Pei-Ying Liu chun-Qing Zhang Wei Liu yan-Hui Wang Tao tang Yi-Fu Ding yan-Dong Zhang Fan-Zhi Meng State Key Laboratory of Fine Chemicals School of Chemical EngineeringDalian University of Technology State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of Sciences Department of Mechanical Engineering University of Colorado Boulder

Poly（ethylene oxide）（PEO） was controllably grafted from styrene-b-（ethylene-co-propylene）-b-styrene （SEPS） backbones by combining lithiation of styrenic units and living monomer-activated anionic ring-opening polymerization of ethylene oxide （EO） monomers with the aid of co-initiators triisobutyl aluminum. The as-synthesized SEPS-g-PEO copolymers were characterized by SEC, 1H-NMR, FTIR, SAXS, AFM and DSC. When the branch length is relatively small, increase of PEO fraction leads to the increase of the correlation length between neighboring hard domains, but the degree of correlation reduces. When the branch length is relatively large, the phase-separated structures become random both in terms of size and spatial correlation, and macro-phase separated structures appear. The crystallization behavior of the PEO branches can be effectively inhibited in SEPS-g-PEO, so no significant crystallization takes place until the fraction of PEO branches is 20.1 wt%, which greatly promotes the rapid delivery of hydrophilic drugs in the hot-melting pressure- sensitive adhesives （HMPSAs） based on SEPS-g-PEO. Their cumulative release amount of a model drug could achieve 80%, more than twice the value in the HMPSAs based on linear PEO-containing styrenic block copolymers.

关键词： Living anionic polymerization SEPS-g-PEO copolymers Phase structures Drug delivery

Effect of SecinH3 on lung injury induced by sepsis of rats

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Asian Pacific Journal of Tropical Medicine 2015年第12期8卷 1020-1024页

作者： Feng Guo chun-yan yan Intensive Care Unit Sir Run Run Shaw HospitalSchool of MedicineZhejiang University Department of Anesthesiology.Sir Run Run Shaw Hospital School of MedicineZhejiang University

Objective:To study effect of SecinH3 on lung injury induced by the sepsis of ***:A total of 30 SPF Wistar rats were randomly divided into two groups,including 5 rats in the control group and 25 in the model *** intraperitoneal injection of endotoxinlipopolysaccharide(LPS) was performed to build the animal model of *** blood gas analysis was carried ***,change in the expression of pro-inflammatory factors of IL-1,IL-6 and TNF- a in the serum were *** study the mechanism of SecinH3 in the process of lung injury induced by the sepsis,the rats with the successful modeling of sepsis were randomly divided into two *** in the SecinH3 group were given the intraperitoneal injection of 100 μg/12 h SecinH3 for 24 h;while rats in the control group were given the injection of same solvent by the same *** blood was drawn from the heart by 500 μL for the blood gas analysis to detect the change in the expression of proinflammatory factors of IL-1,IL-6 and TNF-α in the treatment group and control *** separating the lung tissue,the Real-time PCR and western blotting were performed to analyze the effect of SecinH3 on the expression of cytohesins and also discuss the change of epidermal growth factor receptor(EGFR) and p-EGFR related to the signaling pathway of EGFR-p38mitogen-activated protein kinase that is regulated by ***:Three rats died within 4 h after the injection of LPS,while other 22 ones had the successful modeling,with the success rate of 88%.After being stimulated by LPS,compared with the control group,the arterial partial pressure of oxygen of rats in the treatment group was significantly reduced(P<0.05),while the partial pressure of CO_2 was significantly increased(P<0.01).After being treated by SecinH3,Pa/O_2 was increased with the sepsis,while Pa/CO_2 was decreased with the action of SecinH3,which indicated that SecinH3 had the certain 'repairing' ability for the lung ***3 might in

关键词： Scpsis LPS SecinH3 Acute lung injury

Phase Stability,Elastic,Thermo-physical and Electronic Properties of Hexa-(Mo,Cr,W)_2C from First-principles Calculations

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Journal of Iron and Steel Research International 2016年第10期23卷 1096-1103页

作者： Di WU Wan-tang FU Yong LI chun-xu WANG Jing-lin tang College of Mechanical Engineering Yanshan University Institute for Structural Materials Central Iron and Steel Research Institute State Key Laboratory of Metastable Materials Science and Technology Yanshan University

Phase stability,elastic properties,thermo-physical properties,as well as electronic properties of hexa-（Mo,Cr,W）2C carbides were investigated by first-principles *** results indicated that the Mo8C4,Mo7Cr1C4,Mo7W1C4,Mo6W2C4,and Mo6W1Cr1C4 are stable and the stability follows the sequence：Mo6W1Cr1C4〉Mo7W1C4〉Mo7Cr1C4〉 Mo6W2C4〉 ***6W1Cr1C4 shows the highest stability,deformation resistance and hardness.G/B（shear modulus/bulk modulus）and Poisson′s ratio of the stable hexa-（Mo,Cr,W）2C are all larger than 1.75 and 0.26,respectively,which indicates that they are all *** anisotropies are mainly due to the different Vogit shear modulus/Reuss shear modulus;the mechanical anisotropy of Mo7Cr1C4 is the largest,and that of Mo8C4 is the ***,the obtained Debye temperatureΘDand heat capacity Cpindicate that Mo6W2C4 possesses the best thermal conductivity（ΘD=497.72K）,while Mo7Cr1C4 and Mo6W2C4possess the largest heat capacity when the temperature is in the range of 0-10 Kand larger than 10 K,*** the electronic property analysis,the doped Cr and W atoms can not only participate in orbitals hybridization themselves but also enhance the orbitals hybridization between Mo and C atoms,which can reinforce the interatomic interactions.

关键词： hexa (Mo,Cr, W)2C carbide elastic property electronic structure thermo-physical property first-principles calculation

Interlayer engineering and electronic regulation of MoSe_(2)nanosheets rolledhollow nanospheres for high-performance sodium-ion half/full batteries

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Advanced Powder Materials

Advanced Powder Materials 2024年第2期3卷 26-35页

作者： Jun Xu Junbao Jiang Heng tang Zhao Chen Junwei Chen yan Zhang chun-Sing Lee School of Microelectronics Hefei University of TechnologyHefei 230009China School of Physics Hefei University of TechnologyHefei 230009China Instrumental Analysis Center Hefei University of TechnologyHefei 230009China Department of Chemistry and Center of Super-Diamond and Advanced Films(COSDAF)City University of Hong KongHong KongChina

Layered transition metal dichalcogenides are promising candidates for sodium storage but suffering from low intrinsic electronic conductivity and limited interlayer spacing for fast electron/ion transport,which restricts their high-rate capability and cycling *** this work,rGO@MoSe_(2)/NAC hierarchical architectures,consisting of conductive reduced graphene oxide(rGO)supported by hollow nanospheres that are rolled from superlattices of alternatively overlapped MoSe_(2)and N-doped amorphous carbon(NAC)monolayers,are synthesized as a highperformance sodium storage *** calculations reveal the intercalation of NAC monolayer between two adjacent MoSe_(2)monolayers improving electronic conductivity of MoSe_(2)in both surface and internal bulk to fully accelerate electron transport and enhance Naþ*** interoverlapped MoSe_(2)/NAC superlattice featuring a wide interlayer expansion(72.3%)of MoSe_(2)dramatically decreases Naþdiffusion barriers for fast insertion/***,the hollow nanospheres and the rGO conductive network contribute to a robust hiberarchy that can well release internal stress and buffer the volume expansion,thereby enabling outstanding structural ***,the rGO@MoSe_(2)/NAC anode exhibits excellent high-rate capability of 194 mAh g^(-1)and ultralong cyclability of 12000 cycles with a low capacity fading rate of 0.0038%per cycle at an ultra-high current of 50 A g^(-)1,delivering the best high-rate cycling performance to ***,the Na_(3)V_(2)(PO_(4))_(3)||rGO@MoSe_(2)/NAC full cells also present outstanding cycling stability(600 cycles)at 10C rate,which proves the great potential in fast-charging applications.

关键词： MoSe_(2) Interlayer engineering Dual-carbon modification High-rate capability Sodium-ion batteries

A residual-based message passing algorithm for constraint satisfaction problems

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Communications in Theoretical Physics 2022年第3期74卷 77-86页

作者： chun-yan Zhao yan-Rong Fu Jin-Hua Zhao College of Science University of Shanghai for Science and TechnologyShanghai 200093China Guangdong Provincial Key Laboratory of Nuclear Science Institute of Quantum MatterSouth China Normal UniversityGuangzhou 510006China Guangdong-Hong Kong Joint Laboratory of Quantum Matter Southern Nuclear Science Computing CenterSouth China Normal UniversityGuangzhou 510006China

Message passing algorithms,whose iterative nature captures complicated interactions among interconnected variables in complex systems and extracts information from the fixed point of iterated messages,provide a powerful toolkit in tackling hard computational tasks in optimization,inference,and learning *** the context of constraint satisfaction problems(CSPs),when a control parameter(such as constraint density)is tuned,multiple threshold phenomena emerge,signaling fundamental structural transitions in their solution *** solutions around these transition points is exceedingly challenging for algorithm design,where message passing algorithms suffer from a large message fiuctuation far from *** we introduce a residual-based updating step into message passing algorithms,in which messages with large variation between consecutive steps are given high priority in the updating *** the specific example of model RB(revised B),a typical prototype of random CSPs with growing domains,we show that our algorithm improves the convergence of message updating and increases the success probability in finding solutions around the satisfiability threshold with a low computational *** approach to message passing algorithms should be of value for exploring their power in developing algorithms to find ground-state solutions and understand the detailed structure of solution space of hard optimization problems.

关键词： constraint satisfaction problems model RB message passing algorithms residuals of messages

Distributional Chaos Occurring on the Set of Proper Positive Upper Banach Density Recurrent Points of One-sided Symbolic Systems

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Acta Mathematica Sinica,English Series 2020年第1期36卷 66-76页

作者： yan Jie tang Jian Dong YIN Department of Mathematics Nanchang University

The purpose of this paper is to show that for one-sided symbolic systems,there exists an uncountable distributionally scrambled set contained in the set of proper positive upper Banach density recurrent points.

关键词： Distributional chaos positive upper Banach density recurrent point one-sided symbolic system