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Acute liver failure in Chinese children:a multicenter investigation

Hepatobiliary & Pancreatic Diseases International 2014年第3期13卷 276-280页

作者： Pan Zhao chun-ya wang Wei-Wei Liu Xi wang Li-Ming Yu yan-Rong Sun Liver Failure Therapy and Research Center Beijing 302 Hospital (PLA 302 Hospital) Emergency Department Beijing Anzhen Hospital Capital Medical University Intensive Care Unit Emergency Department General Hospital of PLA Postgraduate Division Academy of Military Medical Science Medical Administration Department Changhai Hospital Second Military Medical University Medical Administration Department General Hospital of Jinan Military Region Medical Administration Department General Hospital of Lanzhou Military Region

BACKGROUND: Currently, no documentation is available regarding Chinese children with acute liver failure(ALF). This study was undertaken to investigate etiologies and outcomes of Chinese children with ***: We retrospectively enrolled 32 pediatric patients with ALF admitted in five hospitals in different areas of China from January 2007 to December 2012. The coagulation indices, serum creatinine, serum lactate dehydrogenase,blood ammonia and prothrombin activity were analyzed; the relationship between these indices and mortality was evaluated by multivariate ***: The most common causes of Chinese children with ALF were indeterminate etiology(15/32), drug toxicity(8/32),and acute cytomegalovirus hepatitis(6/32). Only 1 patient(3.13%)received liver transplantation and the spontaneous mortality of Chinese children with ALF was 58.06%(18/31). Patients who eventually died had higher baseline levels of international normalized ratio(P=0.01), serum creatinine(P=0.04), serum lactate dehydrogenase(P=0.01), blood ammonia(P<0.01) and lower prothrombin activity(P=0.01) than those who *** analysis showed that the entry blood ammonia was the only independent factor significantly associated with mortality(odds ratio=1.069, 95% confidence interval 1.023-1.117,P<0.01) and it had a sensitivity of 94.74%, a specificity of 84.62%and an accuracy of 90.63% for predicting the death. Based on the established model, with an increase of blood ammonia level,the risk of mortality would increase by 6.9%.CONCLUSIONS: The indeterminate causes predominated in the etiologies of ALF in Chinese children. The spontaneous mortality of pediatric patients with ALF was high, whereas the proportion of patients undergoing liver transplantation was significantly low. Entry blood ammonia was a reliable predictor for the death of pediatric patients with ALF.

关键词： acute liver failure children etiology mortality prognosis

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基于亥姆霍兹定理计算动力学系统的哈密顿能量函数

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物理学报 2016年第24期65卷 30-35页

作者：王春妮王亚马军兰州理工大学理学院物理系兰州730050

亥姆霍兹定理表明任意空间矢量场可以分解为涡旋场和梯度场的叠加.由于电磁场变化和电磁波传播则导致电磁场能量的迁移,动力学振子和神经元处于复杂电磁环境下必然伴随能量的吸收和释放.在非线性混沌电路、电容器充电放电以及电感线圈... 详细信息

亥姆霍兹定理表明任意空间矢量场可以分解为涡旋场和梯度场的叠加.由于电磁场变化和电磁波传播则导致电磁场能量的迁移,动力学振子和神经元处于复杂电磁环境下必然伴随能量的吸收和释放.在非线性混沌电路、电容器充电放电以及电感线圈感应过程中都伴随着能量的转换和迁移.包含量纲的非线性振荡电路可利用标度变换方法转换为无量纲的动力学方程.利用平均场理论,电场能量和磁场能量的转换可用若干非线性振荡电路的动力学方程来刻画.基于亥姆霍兹定理来研究一类无量纲非线性动力学系统的哈密顿能量计算问题,对于实际的非线性振荡电路,通过标度变换可快速计算其能量函数.该结果对于动力学系统自适应控制有重要的参考价值.

关键词：亥姆霍兹定理能量函数振荡电路混沌系统

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Lycium barbarum polysaccharide inhibits retinal neovascularization and inflammation in vitro and in vivo

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International Journal of Ophthalmology(English edition) 2025年第2期18卷 216-221页

作者： Bin Wu Xue wang Wei Zhang Xin wang Qi-Miao wang ya-Ju Pang Yi-chun Kong Tianjin Eye Hospital Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Eye InstituteClinical College of Ophthalmology Tianjin Medical UniversityTianjin 300102China Department of Ophthalmology Tianjin Hospital of Integrated Traditional Chinese and Western MedicineTianjin 300100China

AIM:To explore the effect and mechanism of Lycium barbarum polysaccharide(LBP)inhibiting retinal ***:In vitro tests were performed on human retinal microvascular endothelial cells(HRECs)from three groups,including control group(normal oxygen),hypoxic group(hypoxia at 37℃,1%O_(2),5%CO_(2),and 94%N2),and LBP group(hypoxic group with LBP 100μg/mL).In vivo experiments,C57 mice were divided into three groups:control group(normal rearing group),the oxygen-induced ischemic retinopathy(OIR)group,and the OIR with 50 mg/kg LBP *** neovascularization was observed by fluorescein angiography and *** thickness was evaluated by Hematoxylin and eosin(HE)*** expression of epidermal growth factor receptor(EGFR),phosphatidylinositol 3-kinase(PI3K),mammalian target of rapamycin(mTOR),phosphorylated mammalian target of rapamycin(p-mTOR),protein kinase B(AKT),phosphorylated protein kinase B(p-AKT),interleukin-1β(IL-1β),inducible nitric oxide synthase(iNOS),and tumor necrosis factor-α(TNF-α)in each group were analyzed by Western ***-1βlevel in retina was analyzed using immunohistochemical ***:The increased area of neovascular clusters in OIR mice was significantly decreased by *** thickness of OIR mice was significantly thinner compared with normal oxygenated mice and was increased in LBP *** with those in the hypoxic groups,Western blotting of HRECs and retinal tissues revealed that the expression of EGFR,PI3K,p-mTOR,p-AKT,IL-1β,iNOS,and TNF-αdecreased in the LBP group but was still greater than that in control ***,IL-1βwas reduced in retinal sections treated with *** the scratch test,the cell migration of the hypoxic group was significantly greater than that of the control group,while LBP treatment attenuated this increase in ***:LBP reduces retinal neovascularization and inflammation in vivo and inhibits the migration of HRECs in vitro by regulating the EGFR/PI3K/Akt

关键词： Lycium barbarum polysaccharide neovascularization epidermal growth factor receptor retina

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First-episode psychiatric disorder risk from SARS-Co V-2 infection:A clinical analysis with Chinese psychiatric inpatients

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Journal of Biomedical Research 2025年第1期39卷 50-60页

作者： ya Xie Zifeng Xu Yumin Zhang Yisheng Li Pengyu Du chun wang Clinical Mental Health Center the Affiliated Brain Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China Medical School of Nanjing University NanjingJiangsu 210008China

The extensive spread of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)throughout China in late 2022 has underscored the correlation between this virus and severe psychiatric ***,there remains a lack of reported clinical and pathological ***,we retrospectively reviewed the electronic medical records of psychiatric inpatients for seven days from early January ***-one inpatients who developed first-episode psychiatric disorders within two weeks after SARS-CoV-2 infection were recruited,while 24 uninfected first-episode psychiatric inpatients were selected as *** analyses of clinical manifestations,routine laboratory tests,and imaging examinations were *** investigation demonstrated a 330%increase in the incidence of first-episode psychiatric inpatients after SARS-CoV-2 infection in 2023,compared with the preceding year without SARS-CoV-2 *** cases exhibited psychiatric symptoms within one week of SARS-CoV-2 infection,which resolved after approximately two weeks,with no residual symptoms after three ***-way ANOVA demonstrated a significant difference in the highest fever temperature between inpatients with and without psychotic *** inpatients displayed elevated levels of interleukin-4,interleukin-8,and interferon-α,but decreased levels of eosinophils and *** findings suggest that SARS-CoV-2 may contribute to the development of psychiatric disorders,likely mediated by the virus-induced inflammatory response and neuronal dysfunction in the context of psychological distress.

关键词： COVID-19 SARS-CoV-2 psychiatric disorders inflammation interleukins

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Bifurcations and Spatiotemporal Patterns in the Diffusive Nutrient-Microor ganism Model

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Acta Mathematicae Applicatae Sinica 2025年第1期41卷 162-178页

作者： ya-di wang Hai-long YUAN yan-ling LI School of Arts and Sciences Shaanxi University of Science and TechnologyXi'an 710021China School of Mathematics and Statistics Xi'an Jiaotong UniversityXi'an 710049China School of Mathematics and Information Science Shaanxi Normal UniversityXi'an 710062China

In this paper,the diffusive nutrient-microorganism model subject to Neumann boundary conditions is *** Hopf bifurcations and steady state bifurcations which bifurcate from the positive constant equilibrium of the system are investigated in *** addition,the formulae to determine the direction of Hopf and steady state bifurcations are *** results show the existence of spatially homogeneous/nonhomogeneous periodic orbits and steady state solutions,which indicates the spatiotemporal dynamics of the *** numerical simulations are also presented to support the analytical results.

关键词： nutrient-microorganism model Hopf bifurcation steady state bifurcation simulations

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The controlled oxidation states of the H4PMo11VO40 catalyst induced by plasma for the selective oxidation of methacrolein

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Chinese Chemical Letters 2025年第02期36卷 189-194页

作者： Gang Hu chun wang Qinqin wang Mingyuan Zhu Lihua Kang School of Chemistry and Chemical Engineering/State Key Laboratory Incubation Base for Green Processing of Chemical Engineering Shihezi University College of Chemistry&Chemical Engineering Yantai University

In this paper,low-temperature dielectric-blocked discharge plasma （DBD） was employed for the first time to treat silica-doped H4PMo11VO40（HPAV） catalysts (DBD（Ar/x）-MF-Catal) and apply them in the catalytic methacrolein （MAL） selective oxidation to produce methacrylic acid （MAA）.This work investigates in detail the controllable regulation of the concentration of oxidation states on silica-doped HPAV catalysts by adjusting the DBD discharge with controlled changes in voltage,current,treatment time,and treatment *** reports the intrinsic correlation between oxidation states and MAL oxidation *** research results indicated that the catalytic performance was related to the presence of oxygen vacancies and oxygen species (VO2+),and are the main reason for the selective oxidation of MAL to ***,the generation of oxygen vacancies and VO2+altered localized electrons,which resulted in the easier activation of *** calculations of DFT also proved the formation mechanism of oxygen vacancies and VO2+and electron properties on high-performance polymers,which elucidated the intrinsic influence of catalyst *** DBD（Ar/10）-MF-Catal catalysts with suitable VO2+and oxygen vacancy concentrations exhibited the highest catalytic performance with 90%MAL conversion and 70%MAA selectivity and showed good stability （500 h）.

关键词： Catalyst Dopant Methacrolein Methacrylic acid Oxygen vacancy Plasma

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Ideal Bi‑Based Hybrid Anode Material for Ultrafast Charging of Sodium‑Ion Batteries at Extremely Low Temperatures

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Nano-Micro Letters 2025年第3期17卷 152-167页

作者： Jie Bai Jian Hui Jia Yu wang chun Cheng yang Qing Jiang Key Laboratory of Automobile Materials(Jilin University) Ministry of EducationSchool of Materials Science and EngineeringJilin UniversityChangchun 130022People’s Republic of China

Sodium-ion batteries have emerged as competitive substitutes for low-temperature applications due to severe capacity loss and safety concerns of lithium-ion batteries at−20°C or ***,the key capability of ultrafast charging at ultralow temperature for SIBs is rarely ***,a hybrid of Bi nanoparticles embedded in carbon nanorods is demonstrated as an ideal material to address this issue,which is synthesized via a high temperature shock *** a hybrid shows an unprecedented rate performance(237.9 mAh g^(−1) at 2 A g^(−1))at−60℃,outperforming all reported SIB anode *** with a Na_(3)V_(2)(PO_(4))_(3)cathode,the energy density of the full cell can reach to 181.9 Wh kg^(−1) at−40°*** on this work,a novel strategy of high-rate activation is proposed to enhance performances of Bi-based materials in cryogenic conditions by creating new active sites for interfacial reaction under large current.

关键词： Bi nanoparticles High temperature shock High-rate activation Ultrafast charging Low-temperature sodium-ion batteries

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Research progress on piperidine-containing compounds as agrochemicals

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Chinese Chemical Letters 2025年第1期36卷 58-67页

作者： Wei Sun Anjing Liao Li Lei Xu Tang ya wang Jian Wu State Key Laboratory of Green Pesticide Key Laboratory of Green Pesticide and Agricultural BioengineeringMinistry of EducationGuizhou UniversityGuiyang 550025China

Piperidine is a crucial pharmacophore and a special scaffold in the realm of drug *** flexibility increases the molecule’s capability to bind to the *** piperidine-containing compounds are distinguished by their remarkable activity,and are increasingly becoming a vital category of *** this review,the research progress of piperidines in the discovery of pesticides was updated according to their active *** structure-activity relationships(SARs),and mechanisms of action of piperidine-containing compounds were also *** article is meant to enable readers to quickly understand piperidines,while providing ideas for creating piperidines with novel structures and unique mechanisms of action.

关键词： Piperidine Agrochemicals Biological activity Structure-activity relationships Mechanism of action

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Effect of two-pass rolling of textured roll and polished roll on surface topography and mechanical properties of 316L stainless steel ultra-thin strip

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Journal of Iron and Steel Research International 2025年第1期32卷 186-197页

作者： Zeng-qiang Zhang Xi Liao Zhong-kai Ren Zhen-hua wang ya-xing Liu Tao wang Qing-xue Huang College of Mechanical and Vehicle Engineering Taiyuan University of TechnologyTaiyuan030024ShanxiChina Engineering Research Center of Advanced Metal Composites Forming Technology and Equipment of Ministry of Education Taiyuan University of TechnologyTaiyuan030024ShanxiChina National Key Laboratory of Metal Forming Technology and Heavy Equipment Taiyuan University of TechnologyTaiyuan030024ShanxiChina Shanxi TISCO Stainless Steel Precision Strip Co. Ltd.Taiyuan030032ShanxiChina

The textured roll and polished roll were applied instead of the ground roll in a 20-high mill to conduct two-pass rolling of 316L stainless steel strip with thickness of 0.027 *** the two-pass rolling with the textured roll and polished roll(TPR),the surface roughness of the strip is dramatically reduced,and the surface topographical anisotropy index is diminished to 30.9%of the initial *** with the strip rolled using the ground roll in both passes(GGR),the elongation of TPR rolled strip is obviously improved,and the mechanical property anisotropy is greatly *** anisotropy index of tensile strength and elongation are 42.58%and 52.59%of that of GGR rolled strip,which is mainly attributed to the significant decrease of the texture intensity of the strip by TPR *** results indicate that TPR process can obtain the stainless steel ultra-thin strip with smooth and uniform surface topography and good mechanical properties.

关键词： Textured roll Polished roll Surface topography Mechanical property Stainless steel ultra-thin strip

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Masking quantum information in multipartite systems via Fourier and Hadamard matrices

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Communications in Theoretical Physics 2025年第2期77卷 101-111页

作者： Chen-Ming Bai Meng-ya wang Su-Juan Zhang Lu Liu Department of Mathematics and Physics Shijiazhuang Tiedao University

Quantum information masking（QIM） is a crucial technique for protecting quantum data from being accessed by local subsystems. In this paper, we introduce a novel method for achieving1-uniform QIM in multipartite systems utilizing a Fourier matrix. We further extend this approach to construct an orthogonal array with the aid of a Hadamard matrix, which is a specific type of Fourier matrix. This allows us to explore the relationship between 2-uniform QIM and orthogonal arrays. Through this framework, we derive two distinct 2-uniform quantum states,enabling the 2-uniform masking of original information within multipartite ***, we prove that the maximum number of quantum bits required for achieving a2-uniformly masked state is 2~n-1, and the minimum is 2n-1+ 3. Moreover, our scheme effectively demonstrates the rich quantum correlations between multipartite systems and has potential application value in quantum secret sharing.

关键词： multipartite systems quantum information masking Fourier matrix orthogonal arrays

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