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Numerical studies on the boundary entanglement in an optomechanical phonon laser system

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Communications in Theoretical Physics 2020年第11期72卷 37-42页

作者： Qing-Xia meng Zhi-jiao Deng Shi-Wei Cui Department of Physics College of Liberal Arts and SciencesNational University of Defense TechnologyChangsha 410073China Northwest Institute of Nuclear Technology Xi’an 710024ShaanxiChina Interdisciplinary Center for Quantum Information National University of Defense TechnologyChangsha 410073China

In our previous work(meng et al 2020 ***.A 101023838),we discover the phenomenon that the quantum entanglement on the driving threshold line remains a constant in a three-mode optomechanical phonon laser *** this paper,to find the conditions under which the constant boundary entanglement shows up,we explicitly study how this boundary entanglement depends on various parameters through numerical *** results show that the necessary and sufficient condition is a resonant frequency match between the optical frequency difference and the mechanical vibrational frequency,and this constant value is proportional to the multiplication of the square of the optomechanical coupling strength and the resonant driving threshold power.

关键词： boundary entanglement optomechanics phonon laser

SPAGINS:semiempirical parameterization for fragments in gamma-induced nuclear spallation

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Nuclear Science and Techniques 2023年第12期34卷 112-122页

作者： Hui‑Ling Wei meng‑Die Zhou Pu jiao Yu‑Ting Wang Jie Pu Kai‑Xuan Cheng Ya‑Fei Guo chun‑Yuan Qiao Gong‑Tao Fan Hong‑Wei Wang chun‑Wang Ma Institute of Particle and Nuclear Physics College of PhysicsHenan Normal UniversityXinxiang 453007China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201204China Institute of Nuclear Science and Technology Henan Academy of ScienceZhengzhou 450046China

From the empirical phenomena of fragment distributions in nuclear spallation reactions,semiempirical formulas named SPAGINS were constructed to predict fragment cross-sections in high-energyγ-induced nuclear spallation reactions(PNSR).In constructing the SPAGINS formulas,theoretical models,including the TALYS toolkit,SPACS,and Rudstam formulas,were employed to study the general phenomenon of fragment distributions in PNSR with incident energies ranging from 100 to 1000 *** the primary characteristics of PNSR,the SPAGINS formulas modify the EPAX and SPACS formulas and efficiently reproduce the measured *** SPAGINS formulas provide a new and effective tool for predicting fragment production in PNSR.

关键词： High-energy gamma-rays Spallation reaction Fragment cross-section Empirical formula EPAX SPACS TALYS

Salvianolic acids improve liver lipid metabolism in ovariectomized rats via blocking STAT-3/SREBP1 signaling

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Chinese Journal of Natural Medicines 2018年第11期16卷 838-845页

作者： CHEN Juan YUE Jia LIU jiao LIU Yun jiao Kai-Lin TENG meng-Ying HU chun-Yan ZHEN Jing WU Mao-Xuan ZHOU Ming LI Zhong LI Yuan Department of Nutrition and Food Hygiene School of Public Health Nanjing Medical University Department of Nutrition and Food Hygiene School of Public Health Gansu University of Chinese Medicine

Postmenopausal women, who have reduced circulating estrogen levels, are more prone to develop obesity and related metabolic diseases than premenopausal women. The absence of safe and effective treatments for postmenopausal obesity has changed the focus to natural products as alternative remedies. Total salvianolic acids(TSA) are the major water-soluble ingredients of Danshen. Salvianolic acid(SA) is the major constituent of the TSA. Salvianolic acids, including TSA and SA, are widely used in traditional Chinese medicine. In the present study, ovariectomized rats and LO2 cells were used to study the effects of salvianolic acids on body weight gain and hepatic steatosis. Salvianolic acids reduced ovariectomy(OVX)-induced body weight gain, attenuated the expressions of hepatic lipogenic genes, such as sterol regulatory element binding protein(SREBP)1, fatty acid synthase(FAS), and stearoyl-CoA desaturase(SCD)1, and decreased the liver triglyceride(TG) and total cholesterol(TC). For the molecular mechanisms, OVX and high glucose-induced phosphorylation of signal transducer and activator of transcription(STAT)-3 was inhibited by salvianolic acids treatment. In LO2 cells, inhibition of STAT-3 by siRNA attenuated the increased expression of SREBP1 and TG induced by high glucose. Salvianolic acids reduced the upregulation of SREBP1 and TG induced by high glucose in LO2 cells. In conclusion, these findings illustrated that salvianolic acids markedly alleviated the lipid metabolism disorders and protected against the postmenopausal obesity. The underlying mechanism was probably associated with the regulation of STAT-3 signaling.

关键词： Salvianolic acids Lipid metabolism Weight gain Signal transducer and activator of transcription 3

Study on NiO/Fe interface with X-ray photoelectron spectroscopy

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International Journal of Minerals,Metallurgy and Materials 2010年第6期17卷 777-781页

作者： chun Feng Jing-yan Zhang jiao Teng Fu-ming Wang School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China School of Metallurgical and Ecological Engineering University of Science and Technology Beijing Beijing 100083 China

Different monolayers （ML） of Fe atoms were deposited on NiO （001） substrates or NiO underlayers using molecular beam epitaxy （MBE）, pulse laser deposition （PLD）, and magnetron sputtering （MS）. The magnetic properties and microstructure of the films were studied. The apparent magnetic dead layer （MDL） is found to exist at the NiO/Fe interfaces of the MBE sample （about 2 ML MDL）, the PLD sample （about 3 ML MDL）, and the MS sample （about 4 ML MDL）. X-ray photoelectron spectroscopy indicates the presence of ionic Fe （Fe2＋ or Fe3＋） and metallic Ni at the NiO/Fe interfaces, which may be due to the chemical reactions between Fe and NiO layers. This also leads to the formation of MDL. The thickness of the MDL and the reaction products are related with the deposition energy of the atoms on the substrates. The interfacial reactions are effectively suppressed by inserting a thin Pt layer at the NiO/Fe interface.

关键词： interracial reaction magnetic films X-ray photoelectron spectroscopy magnetic properties microstructure

Enhanced metastasis in RNF13 knockout mice s mediated by a reduction in GM-CSF levels

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Protein & Cell 2015年第10期6卷 746-756页

作者： He Cheng Aodi Wang jiao meng Yong Zhang Dahai Zhu The National Laboratory of Medical Molecular Biology Institute of Basic Medical Sciences Chinese Academy of MedicalSciences and School of Basic Medicine Peking Union Medical College Beijing 100005 China

RING finger protein 13 （RNF13） is a novel E3 ubiquitin ligase whose expression is associated with cancer development. However, its specific role in cancer progression and metastasis remains unclear. Here, a B16F10/LLC experimental pulmonary metastatic model was developed to examine the formation of metastatic foci in the lung. A greater number of tumor colonies were observed in the lungs of RNF13-knockout （KO） mice than in their wild-type （WT） littermates, whereas no significant differences in tumor size were observed between the two groups. In short-term experiments, the number of fluorescently-labeled B16F10 cells increased remarkably in RNF13-KO lungs at early time points, whereas clearance of tumor cells from the blood was not affected. These results indicated that RNF13 may inhibit the colonization of B16F10 cells in the lung. Assessment of the concentration of various cytokines in tumor bearing lungs and blood did not detect significant dif- ferences between the blood of RNF13-KO and WT mice; however the levels of GM-CSF were significantly reduced in RNF13-KO tumor bearing lungs, which may have guided more B16F10 cells to migrate to the lungs. This was confirmed by lower GM-CSF concentrations in conditioned media from the culture of RNF13-KO lung slices. Collectively, our results suggest that host RNF13 affects the concentration of GM-CSF in tumor-bearing lungs, leading to a reduction in the colonization of metastatic tumor cells in the lung.

关键词： RNF13 metastasis GM-CSF lung cancer

Application of CRISPR/Cas9 in plant biology

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Acta Pharmaceutica Sinica B 2017年第3期7卷 292-302页

作者： Xuan Liu Surui Wu jiao Xu chun Sui Jianhe Wei Institute of Medicinal Plant Development Chinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100193China

The CRISPR/Cas(clustered regularly interspaced short palindromic repeats/CRISPRassociated proteins) system was first identified in bacteria and archaea and can degrade exogenous substrates. It was developed as a gene editing technology in 2013. Over the subsequent years, it has received extensive attention owing to its easy manipulation, high efficiency, and wide application in gene mutation and transcriptional regulation in mammals and plants. The process of CRISPR/Cas is optimized constantly and its application has also expanded dramatically. Therefore, CRISPR/Cas is considered a revolutionary technology in plant biology. Here, we introduce the mechanism of the type II CRISPR/Cas called CRISPR/Cas9, update its recent advances in various applications in plants, and discuss its future prospects to provide an argument for its use in the study of medicinal plants.

关键词： CRISPR/Cas system Gene editing technology Gene modification Plant biology Transcriptional regulation

Formation mechanism of the protective layer in a blast furnace hearth

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International Journal of Minerals,Metallurgy and Materials 2015年第10期22卷 1017-1024页

作者： Ke-xin jiao Jian-liang Zhang Zheng-jian Liu meng Xu Feng Liu School of Metallurgical and Ecological Engineering University of Science and Technology Beijing State Key Laboratory of Advanced Metallurgy University of Science and Technology Beijing Shougang Research Institute of Technology

A variety of techniques, such as chemical analysis, scanning electron microscopy-energy dispersive spectroscopy, and X-ray diffraction, were applied to characterize the adhesion protective layer formed below the blast furnace taphole level when a certain amount of titanium-bearing burden was used. Samples of the protective layer were extracted to identify the chemical composition, phase assemblage, andistribution. Furthermore, the formation mechanism of the protective layer was determined after clarifying the source of each componenFinally, a technical strategy was proposed for achieving a stable protective layer in the hearth. The results show that the protective layemainly exists in a bilayer form in the sidewall, namely, a titanium-bearing layer and a graphite layer. Both the layers contain the slag phaswhose major crystalline phase is magnesium melilite（Ca2Mg Si2O7） and the main source of the slag phase is coke ash. It is clearly determinethat solid particles such as graphite, Ti（C,N） and Mg Al2O4play an important role in the formation of the protective layer, and the key factofor promoting the formation of a stable protective layer is reasonable control of the evolution behavior of coke.

关键词： blast furnaces hearths protective layers electroch

QTL mapping of seedling biomass and root traits under different nitrogen conditions in bread wheat(Triticum aestivum L.)

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Journal of Integrative Agriculture 2021年第5期20卷 1180-1192页

作者： YANG meng-jiao WANG Cai-rong Muhammad Adeel HASSAN WU Yu-ying XIA Xian-chun SHI Shu-bing XIAO Yong-gui HE Zhong-hu College of Agriculture Xinjiang Agricultural UniversityUrumqi 830052P.R.China National Wheat Improvement Centre Institute of Crop SciencesChinese Academy of Agricultural Sciences(CAAS)Beijing 100081P.R.China Institute of Agricultural Science of Yili Prefecture Yining 835000P.R.China International Maize and Wheat Improvement Centre(CIMMYT)China Office c/o CAASBeijing 100081P.R.China

Plant nitrogen assimilation and use efficiency in the seedling's root system are beneficial for adult plants in field condition for yield *** of the genetic basis between root traits and N uptake plays a crucial role in wheat *** the present study,198 doubled haploid lines from the cross of Yangmai 16/Zhongmai 895 were used to identify quantitative trait loci(QTLs)underpinning four seedling biomass traits and five root system architecture(RSA)related *** plants were grown under hydroponic conditions with control,low and high N treatments(Ca(NO_(3))_(2)·4H_(2)O at 0,0.05 and 2.0 mmol L^(-1),respectively).Significant variations among the treatments and genotypes,and positive correlations between seedling biomass and RSA traits(r=0.20 to 0.98)were *** composite interval mapping based on a high-density map from the Wheat 660 K single nucleotide polymorphisms(SNP)array identified 51 QTLs from the three N *** new QTLs detected on chromosomes 1 AL(1)in the control,1 DS(2)in high N treatment,4 BL(5)in low and high N treatments,and 7 DS(3)and 7 DL(1)in low N treatments,are first reported in influencing the root and biomass related traits for N *** most stable QTLs(***-4 DS)on chromosome 4 DS,which were related to ratio of root to shoot dry weight trait,was in close proximity of the Rht-D1 gene,and it showed high phenotypic effects,explaining 13.1%of the phenotypic ***-eight QTLs were clustered in 12 genetic *** markers tightly linked to two important QTLs clusters C10 and C11 on chromosomes 6 BL and 7 BL were converted to kompetitive allele-specific PCR(KASP)assays that underpin important traits in root development,including root dry weight,root surface area and shoot dry *** QTLs,clusters and KASP assays can greatly improve the efficiency of selection for root traits in wheat breeding programmes.

关键词： KASP marker QTL analysis root traits SNP array Triticum aestivum

Neuronal intranuclear inclusion disease mimicking acute cerebellitis:A case report

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World Journal of Clinical Cases 2020年第23期8卷 6122-6129页

作者： jiao-jiao Guo Zi-Yi Wang meng Wang Zong-Zhi Jiang Xue-Fan Yu Department of Neurology and Neuroscience Center The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

BACKGROUND Neuronal intranuclear inclusion disease(NIID)is an unusual autosomal dominant,chronic progressive neurodegenerative *** clinical manifestations of NIID are complex and varied,complicating its clinical *** the best of our knowledge,this report is the first to document sporadic adult-onset NIID mimicking acute cerebellitis(AC)that was finally diagnosed by imaging studies,skin biopsy,and genetic *** SUMMARY A 63-year-old man presented with fever,gait unsteadiness,dysarthria,and an episode of *** serum levels of white blood cells and C-reactive protein were significantly elevated.T2-weighted brain magnetic resonance imaging and fluid attenuation inversion recovery sequences showed bilateral high-intensity signals in the medial part of the cerebellar hemisphere beside the *** we initially considered a diagnosis of AC,the patient’s symptoms improved significantly without special treatment,prompting our consideration of ***-weighted imaging showed hyperintensity in the corticomedullary *** biopsy revealed eosinophilic inclusions positive for anti-p62 in epithelial sweat-gland *** repeat expansions in the Notch 2 N-terminal like C gene confirmed the diagnosis of *** For patients with clinical manifestations mimicking AC,the possibility of underlying NIID should be considered along with prompt rigorous examinations.

关键词： Neuronal intranuclear inclusion disease Acute cerebellitis Skin biopsy Genetic testing Magnetic resonance imaging Case report