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Association of visceral obesity and early colorectal neoplasia

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World Journal of Gastroenterology 2013年第45期19卷 8349-8356页

作者： Eun Kyung choe Donghee Kim hwa Jung Kim Kyu Joo Park Department of Surgery Healthcare Research Institute Seoul National University Hospital Healthcare System Gangnam Center Seoul 135-984 South Korea Department of Internal Medicine Healthcare Research Institute Seoul National University Hospital Healthcare System Gangnam Center Seoul 135-984 South Korea Department of Clinical Epidemiology and Biostatistics Asan Medical Center University of Ulsan College of Medicine Seoul 138-736 South Korea Department of Surgery Seoul National University College of Medicine Seoul 110-799 South Korea

AIM:To examine whether visceral adipose tissue(VAT)serves as a risk factor for colorectal adenoma-early colorectal cancer(CRC)***:A retrospective case-control study was conducted with 153 patients with stageⅠCRC,age/sex-matched 554 patients with colorectal adenoma and557 normal *** subjects underwent various laboratory tests,abdominal fat computed tomography(CT),and *** was defined as an intraabdominal adipose tissue area measured by CT *** tissue area was measured at the level of the umbilicus from CT *** used the lowest quartile of VAT and subcutaneous adipose tissue area as a reference ***:The body mass index(BMI),total cholesterol,fasting glucose and VAT areas were significantly different among normal,adenoma and CRC *** VAT area was 120.6±49.0 cm2in normal controls,130.6±58.4 cm2in adenoma group and 117.6±51.6cm2in CRC group(P=0.002).In univariate analysis,increased BMI was a risk factor for CRC compared to control(P=0.025).However,VAT area was not a risk factor for CRC compared to *** multivariate analysis that adjusted for smoking,alcohol consumption and subcutaneous adipose tissue area,VAT area was inversely related to CRC,compared to the adenoma(OR=0.53,95%CI:0.31-0.92,highest quartile vs lowest quartile).CONCLUSION:Our study shows that visceral obesity is not a risk factor for early *** obesity might influence the normal-adenoma sequence but not the adenoma-early carcinoma sequence.

关键词： Adipose tissue Visceral fat Obesity Colorectal cancer Colorectal adenoma Abdominal computed tomography

What physicians should know about the management of chronic hepatitis B in children: East side story

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World Journal of Gastroenterology 2014年第13期20卷 3582-3589页

作者： Hun-Jee choe Byung-Ho choe Seoul National University College of Medicine Seoul 110-799South Korea Department of Pediatrics Kyungpook National University School of MedicineDaegu 700-721South Korea

Understanding the natural course of chronic hepatitis B virus(HBV)infection is very important for the management and treatment of chronic hepatitis B in *** on treatment guidelines,the management of HBV carriers and treatment of active hepatitis have been advancing and resulted in increased survival,as well as decreased risks of complications such as liver cirrhosis and hepatocellular *** of a continuing medical education(CME)program for primary physicians becomes an important responsibility of pediatric *** could prevent misdiagnosis and unnecessary treatment that could lead to liver complications or antiviral *** addition,education of patients and their parents is necessary to achieve better therapeutic outcomes.

关键词： Hepatitis B virus Natural course Diagnosis Treatment Lamivudine Resistance

Fouling evaluation on membrane distillation used for reducing solvent in polyphenol rich propolis extract

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Chinese Journal of Chemical Engineering 2018年第3期26卷 477-483页

作者： Norhaziyana Hamzah choe Peng Leo School of Chemical Engineering Engineering Campus Universiti Sains Malaysia

Membrane distillation(MD) has not been widely studied in the concentrate of phenolic rich solution in comparison to osmotic distillation. In this work, the potential of MD to reduce solvent in the polyphenol rich propolis extract was further investigated. Polyvinylidene fluoride(PVDF) membranes were engineered with the smaller pore size for the less hydrophobic surface in order to avoid wetting, allowing only the solvent vapor to be transferred from the warm feed into the cold permeate. All the membranes exhibited more than 95% rejection of phenolic and flavonoid compounds. Although the hydrophilic membranes exhibited less fouling, they displayed a lower flux than the hydrophobic membrane due to the hindrance in the wetted pores. The hydrophobic membrane was seriously fouled by the phenolic acid as shown in the Fourier transform infrared spectroscopy spectrum. Pore plugging occurred on these hydrophobic membranes as confirmed in the scanning electron microscope images.

关键词： Membrane distillation Propolis Fouling

Spontaneous high-frequency action potential

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Science China(Life Sciences) 2011年第4期54卷 311-335页

作者： Wonchae choe Department of Biochemistry and Molecular Biology Medical Research Center and Biomedical Science InstituteSchool of MedicineKyung Hee University

Action potential,which is the foundation of physiology and electrophysiology,is most vital in physiological *** work starts by detecting cardiac electrophysiology(tachyarrhythmias),combined with all spontaneous discharge phenomena in vivo such as wound currents and spontaneous neuropathic pain,elaborates from generation,induction,initiation,to all of the features of spontaneous high-frequency action potential--SSL action potential mechanism,i.e.,connecting-end hyperpolarization initiates spontaneous depolarization and action potential in somatic *** work resolves the conundrums of in vivo spontaneous discharge in tachyarrhythmias,wounds,denervation supersensitivity,neurogenic pain(hyperalgesia and allodynia),epileptic discharge and diabetic pain in pathophysiological and clinical researches that have puzzled people for a hundred years.

关键词： action potential spontaneous high-frequency action potential tachyarrhythmias atrial fibrillation wound denervation supersensitivity neurogenic pain hyperalgesia and allodynia epileptic discharge diabetic pain regeneration and development

Data-driven sparse polynomial chaos expansion for models with dependent inputs

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Journal of Safety Science and Resilience 2023年第4期4卷 358-365页

作者： Zhanlin Liu Youngjun choe Industrial&Systems Engineering University of WashingtonSeattleWAUSA

Polynomial chaos expansions(PCEs)have been used in many real-world engineering applications to quantify how the uncertainty of an output is propagated from inputs by decomposing the output in terms of polynomials of the *** for models with independent inputs have been extensively explored in the ***,different approaches have been proposed for models with dependent inputs to expand the use of PCEs to more real-world *** approaches include building PCEs based on the Gram–Schmidt algorithm or transforming the dependent inputs into independent ***,the two approaches have their limitations regarding computational efficiency and additional assumptions about the input distributions,*** this paper,we propose a data-driven approach to build sparse PCEs for models with dependent inputs without any distributional *** proposed algorithm recursively constructs orthonormal polynomials using a set of monomials based on their correlations with the *** proposed algorithm on building sparse PCEs not only reduces the number of minimally required observations but also improves the numerical stability and computational *** numerical examples are implemented to validate the proposed *** source code is made publicly available for reproducibility.

关键词： Uncertainty quantification Polynomial chaos expansion Sparse polynomial chaos expansion Gram-Schmidt orthogonalization

Dominant edge direction based fast intra mode decision in the H.264/AVC encoder

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第6期10卷 767-777页

作者： Byeongdu LA Minyoung EOM Yoonsik choe Department of Electrical and Electronic Engineering Yonsei University

The H.264/AVC video coding standard uses an intra prediction mode with 4×4 and 16×16 blocks for luma and 8×8 blocks for chroma. This standard uses the rate distortion optimization (RDO) method to determine the best coding mode based on the compression performance and video quality. This method offers a large improvement in coding efficiency compared to other compression standards, but the computational complexity is greater due to the various intra prediction modes. This paper proposes a fast intra mode decision algorithm for real-time encoding of H.264/AVC based on the dominant edge direction (DED). The DED is extracted using pixel value summation and subtraction in the horizontal and vertical directions. By using the DED, three modes instead of nine are chosen for RDO calculation to decide on the best mode in the 4×4 luma block. For the 16×16 luma and the 8×8 chroma, only two modes are chosen instead of four. Experimental results show that the entire encoding time saving of the proposed algorithm is about 67% compared to the full intra search method with negligible loss of quality.

关键词： H 264 Intra prediction Mode decision Dominant edge direction

Nanostructure and corrosion behaviors of nanotube formed Ti-Zr alloy

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中国有色金属学会会刊：英文版 2009年第4期19卷 1005-1008页

作者： Won-Gi KIM Han-Cheol choe Department of Dental Materials & Research Center of Nano-Interface Activation for Biomaterials College of DentistryChosun University

In order to investigate the nanostructures and corrosion behaviors of Ti-Zr alloys,nanotube formed Ti-Zr(10%,20%,30% and 40% in mass fraction) alloys were prepared by arc melting and the condition of controlling nanostructure was at 1 000 ℃ for 24 h in argon atmosphere;formation of nanotubes was conducted by anodizing a Ti-Zr alloy in H3PO4 electrolyte with a small amount of fluoride ions at room *** corrosion properties of specimens were examined through potentiodynamic test(potential range of -1 500-2 000 mV) in 0.9% NaCl solution by using *** of the alloys were observed by optical microscope(OM),field emission scanning electron microscope(FE-SEM) and X-ray diffractometer(XRD).Diameter of nanotube does not depend on Zr content,but interspace of nanotube predominantly depends on Zr content,which confirms that ZrO2 oxides play a role to increase the interspace of nanotube formed on the surface.

关键词：钛锆合金纳米结构腐蚀行为扫描电子显微镜 NaCl溶液阳极氧化光学显微镜 X射线衍射

Electrochemical behavior of Co-Cr and Ni-Cr dental cast alloys

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中国有色金属学会会刊：英文版 2009年第4期19卷 785-790页

作者： Viswanathan S. SAJI Han-Cheol choe Department of Dental Materials College of DentistryChosun University

The cast structures influencing the electrochemical corrosion behavior of Co-Cr and Ni-Cr dental alloys were studied using potentiodynamic polarization and AC impedance in 0.9% (mass fraction) NaCl solution at (37±1) ℃. The phase and microstructure of the alloys that were fabricated using two different casting methods viz. centrifugal casting and high frequency induction casting, were examined using X-ray diffraction analysis, scanning electron microscopy and energy dispersive spectroscopy. The roles of alloying elements and the passive film homogeneity on the corrosion resistance of Co-Cr-Mo and Ni-Cr-Mo dental cast alloys were reviewed. The results of electrochemical study show that the dependence of corrosion resistance on the microstructure associated with the casting methods is marginal. The Co-Cr alloy exhibits more desirable corrosion resistance properties than the Ni-Cr alloy. There is severe preferential dissolution of Ni-rich, Cr and Mo depleted zones in the Ni-Cr alloy.

关键词：镍铬合金合金铸造电化学行为牙科电化学腐蚀行为 X射线衍射分析 NaCl溶液钴

COVID-19 economic policy effects on consumer spending and foot traffic in the U.S.

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Journal of Safety Science and Resilience 2021年第4期2卷 230-237页

作者： Zhiqing Yang Youngjun choe Matthew Martell Department of Statistics University of WashingtonUnited States Information School University of WashingtonUnited States Department of Industrial&Systems Engineering University of WashingtonUnited States

To battle with economic challenges during the COVID-19 pandemic,the US government implemented various measures to mitigate economic *** issuance of stimulus checks to reopening businesses,consumers had to constantly alter their behavior in response to government *** anonymized card transactions and mobile device-based location tracking data,we analyze the factors that contribute to these behavior changes,focusing on stimulus check issuance and state-wide *** finding suggests that stimulus payment has a significant immediate effect of boosting spending,but it typically does not reverse a downward ***-wide reopening had a small effect on *** traffic increased gradually after stimulus check issuance,but only increased slightly after reopening,which also coincided or preceded several policy changes and confounding events(e.g.,protests)in the *** also find differences in the reaction to these policies in different regions in the *** results may be used to inform future economic recovery policies and their potential consumer response.

关键词： COVID-19 Economic impact Interrupted time series analysis