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Renin-angiotensin system inhibitors prescriptions in Chinese hospitalized chronic kidney disease patients

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World Journal of Clinical Cases 2024年第17期12卷 3061-3075页

作者： chun Zhang Zhi-Yu duan Sa-Sa Nie Zhou Zhang Xin-Ru Guo Chao-Yang Zhang Jing Dong Guang-Yan Cai Department of Nephrology The First Medical CentreChinese PLA General HospitalBeijing 100853China School of Medicine Nankai UniversityTianjin 300071China National Engineering Laboratory for Medical Big Data Application Technology Chinese PLA General HospitalBeijing 100853China

BACKGROUND Many guidelines have recommended renin-angiotensin system inhibitors(RASI)as the first-line treatment for patients with chronic kidney disease(CKD).We studied RASI prescription trends from 2010 to 2019,and analyzed the characteristics associated with RASI prescription in Chinese hospitalized CKD *** To study the prescription of renin angiotensin system inhibitors in hospitalized patients with CKD in *** It was retrospectively,cross-sectional reviewed RASI prescriptions in hospitalized CKD patients in China from 2010 to *** prescribing trends were analyzed from 2010 to 2019,and bivariate and multivariate logistic regression analyses were conducted to identify characteristics associated with RASI *** A total of 35090 CKD patients were included,with 10043(28.6%)RASI *** these patients,18919(53.9%)met the criteria for RASI treatments based on the 2012 kidney disease:Improving global outcomes *** these,7246(38.3%)patients received RASI *** prescriptions showed an initial rapid increase from 2011 to 2012,reached its peak around 2015 and 2016,and then exhibited a subsequent slight decreasing *** bivariate and multivariate analyses showed that several characteristics,including the male gender,age less than 60-year-old,nephrology department admission,lower CKD stage,history of hypertension or diabetes,proteinuria,glomerulonephritis as the CKD etiology,and non-acute kidney injury were associated with RASI *** The frequency of RASI prescriptions showed an initial increase but a slight decreasing trend in more recent *** patients with certain characteristics such as elderly age,advanced disease stage,surgery department admission,or acute kidney injury were less likely to receive RASI *** the application of RASI in hospitalized CKD patients is *** actual clinical practice needs to be *** development of related research

关键词： Chronic kidney disease Renin-angiotensin system inhibitors Prescriptions Adherence

新型载流子积累的逆导型横向绝缘栅双极晶体管

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物理学报 2024年第15期73卷 179-186页

作者：段宝兴王佳森唐春萍杨银堂西安电子科技大学微电子学院宽禁带半导体材料与器件教育部重点实验室西安710071

通过引入n^(+)阳极在体内集成续流二极管的逆导型横向绝缘栅双极晶体管(reverse-conducting lateral insulated gate bipolar transistor,RC-LIGBT)可以实现反向导通,并且优化器件的关断特性,是功率集成电路中一个有竞争力的器件.本文... 详细信息

通过引入n^(+)阳极在体内集成续流二极管的逆导型横向绝缘栅双极晶体管(reverse-conducting lateral insulated gate bipolar transistor,RC-LIGBT)可以实现反向导通,并且优化器件的关断特性,是功率集成电路中一个有竞争力的器件.本文提出了一种新型载流子积累的RC-LIGBT,它具有电子控制栅(electron-controlled gate,EG)和分离短路阳极(separated short-anode,SSA),可以同时实现较低的导通压降和关断损耗.在正向导通状态,漂移区上方的EG结构可以在漂移区的表面积累一个高密度的电子层,从而大大地降低器件的导通压降.同时,SSA结构的使用还极大优化了器件的关断损耗.另外,低掺杂p型漂移区与SSA结构配合,可以简单地实现反向导通并且消除回吸电压.仿真结果表明,所提出的器件具有优秀的导通压降与关断损耗之间的折衷关系,其导通压降为1.16 V,比SSA LIGBT低55%,其关断损耗为0.099 mJ/cm^(2),比SSA LIGBT和常规LIGBT分别低38.5%和94.7%.

关键词：载流子积累逆导型横向绝缘栅双极晶体管导通压降回吸电压

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铌酸锂包层硫系中红外少模光纤的电光效应

北京邮电大学学报 2024年第1期47卷 112-119页

作者：段博侯尚林雷景丽武刚晏祖勇兰州理工大学理学院兰州730050

提出了一种采用LiNbO3晶体为包层、光轴方向沿光纤轴线方向的中红外硫系少模光纤,采用全矢量有限元法研究了外加电场对LiNbO3晶体的主轴折射率比和光模式的传输特性的影响。结果表明,在2.25~3.85μm波长范围内,模式有效折射率与功率限... 详细信息

提出了一种采用LiNbO3晶体为包层、光轴方向沿光纤轴线方向的中红外硫系少模光纤,采用全矢量有限元法研究了外加电场对LiNbO3晶体的主轴折射率比和光模式的传输特性的影响。结果表明,在2.25~3.85μm波长范围内,模式有效折射率与功率限制因子均随着波长增大逐渐降低,而差分模时延呈现上升趋势。外加轴向电场不但会减小各光模式的有效折射率与差分模时延,而且会增强对各模式能量的限制,并随着模式阶数升高,电场的限制就愈发明显。无外加电场时HE11模色散随波长增大而呈现上升趋势,而HE_(21),TE_(01)和TM_(01)模色散呈现抛物线型分布,且存在2个零色散波长。当电场增大时,光模式的色散均会增大并会导致色散零点蓝移。电场为4×10^(9)V/m时,HE_(11),HE_(21),TE_(01)和TM_(01)模短波长处的零色散波长比无电场时分别蓝移0.5695μm,0.3915μm,0.3862μm和0.5594μm。

关键词：少模光纤铌酸锂三硫化二砷电光效应色散

Formation of mesophase microbeads from bulk mesophase pitch induced by fullerene

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新型炭材料（中英文） 2024年第4期39卷 645-654页

作者： CHEN Wen-sheng LIU Lan-tao WANG Zheng duan chun-feng ZHANG Xing-wei MA Zhao-kun CHEN Xiao-hong SONG Huai-he State Key Laboratory of Chemical Resource Engineering Beijing Key Laboratory of Electrochemical Process and Technology for MaterialsBeijing Uni-versity of Chemical TechnologyBeijing 100029China

A transformation of naphthalene-based coalescenced mesophase pitch(NMP)to mesophase microbeads was achieved by heating a mixture of NMP and fullerene(C_(60)).This is different from the conventional process of the liquid-phase carbonization of isotropic pitch to the emergence of carbon microbeads in the matrix and finally their growth to form a 100%anisotropic bulk meso-phase,but rather a reverse *** effects of C_(60) loading and reaction temperature on the morphological transformation of mesophase were investigated by polarizing optical and scanning electron *** physical changes in the NMP induced by C_(60) were characterized by thermogravimetric analysis,Fourier transform infrared spectroscopy,X-ray diffractometry and Raman *** results show that the coalesced NMP can be converted to a spherical type at 300-320℃ with the addition of 5%C_(60),and the size of the mesophase microbeads increases with increasing ***,a model is established to ex-plain the unique induction effect of C_(60) in the transformation *** work makes the morphological transformation of MP con-trollable,and provides a new idea for the understanding and research of mesophase pitch.

关键词： Reversible transformation Fullerene induction mechanism Mesophase texture π-electron-induced effect Mesophase microbeads

Genomic evolution and insights into agronomic trait innovations of Sesamum species

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Plant Communications 2024年第1期5卷 262-283页

作者： Hongmei Miao Lei Wang Lingbo Qu Hongyan Liu Yamin Sun Meiwang Le Qiang Wang Shuangling Wei Yongzhan Zheng Wenchao Lin Yinghui duan Hengchun Cao Songjin Xiong Xuede Wang Libin Wei chun Li Qin Ma Ming Ju Ruihong Zhao Guiting Li Cong Mu Qiuzhen Tian Hongxian Mei Tide Zhang Tongmei Gao Haiyang Zhang Henan Sesame Research Center Henan Academy of Agricultural SciencesZhengzhou 450002China TEDA School of Biological Sciences and Biotechnology Nankai UniversityTianjin 300457China College of Food Science and Technology Henan Technology UniversityZhengzhou 450001China Institute of Plant Protection Research Henan Academy of Agricultural SciencesZhengzhou 450002China Crops Research Institute Jiangxi Academy of Agricultural SciencesNanchang 330200China Crop Research Institute Anhui Academy of Agricultural SciencesHefei 230031China

Sesame is an ancient oilseed crop with high oil content and ***,the evolutionary history and genetic mechanisms of its valuable agronomic traits remain ***,we report chromosome-scale genomes of cultivated sesame(Sesamum indicum L.)and six wild Sesamum species,representing all three karyotypes within this *** and genome-based phylogenic analysis revealed the evolutionary route of Sesamum species from n=13 to n=16 and revealed that allotetraploidization occurred in the wild species Sesamum *** divergence of the Sesamum genus(48.5–19.7 million years ago)during the Tertiary period and its ancient phylogenic position within eudicots were ***-genome analysis revealed 9164 core gene families in the *** families are significantly enriched in variousmetabolic pathways,including fatty acid(FA)metabolism and FA *** variations in SiPT1 and SiDT1 within the phosphatidyl ethanolamine-binding protein gene family lead to the genomic evolution of plant-architecture and inflorescence-development phenotypes in Sesamum.A genome-wide association study(GWAS)of an interspecific population and genome comparisons revealed a long terminal repeat insertion and a sequence deletion inDIR genes of wildSesamum angustifoliumand cultivated sesame,respectively;both variations independently cause high susceptibility toFusariumwilt disease.A GWAS of 560 sesame accessions combined with an overexpression study confirmed that the NAC1andPPOgenes play an important role in upregulating oil content of *** study provides high-quality genomic resources for cultivated and wild Sesamum species and insights that can improve molecular breeding strategies for sesame and other oilseed crops.

关键词： Sesamum genome evolution structural variation plant architecture Fusarium wilt disease oil content

肖特基结多数载流子积累新型绝缘栅双极晶体管

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Electric field-driven folding of single molecules

物理学报 2024年第7期73卷 325-332页

作者：段宝兴刘雨林唐春萍杨银堂西安电子科技大学微电子学院宽禁带半导体材料与器件教育部重点实验室西安 710071

绝缘栅双极晶体管(insulated gate bipolar transistor,IGBT)是现代功率半导体器件的核心,因其良好的电学特性得到了广泛的应用.本文提出了一种具有肖特基结接触的栅半导体层新型多数载流子积累模式IGBT,并对其进行特性研究和仿真分析.... 详细信息

绝缘栅双极晶体管(insulated gate bipolar transistor,IGBT)是现代功率半导体器件的核心,因其良好的电学特性得到了广泛的应用.本文提出了一种具有肖特基结接触的栅半导体层新型多数载流子积累模式IGBT,并对其进行特性研究和仿真分析.当新型IGBT处于导通状态,栅极施加正向偏压,由于肖特基势垒二极管极低的正向导通压降,使得栅半导体层的电压几乎等于栅极电压,从而能够在漂移区中积累大量的多数载流子电子.除了现有的电子外,这些积累的电子增大了漂移区的电导率,从而显著降低了正向导通压降.因此,打破了传统IGBT正向导通压降受漂移区掺杂浓度的限制.轻掺杂的漂移区可以使新型IGBT具有较高的击穿电压,同时减小了关断过程中器件内部耗尽层电容,因此整体米勒电容减小,提升了关断速度,减小了关断时间和关断损耗.分析结果表明,600 V级别的击穿电压时,新型IGBT的正向导通压降,关断损耗和关断时间相比常规IGBT分别降低了 46.2％,52.5％,30％,打破了 IGBT中正向导通压降和关断损耗之间的矛盾.此外,新型IGBT具有更高的抗闩锁能力和更大的正偏安全工作区.新型结构的提出满足了未来IGBT器件性能的发展要求,对于功率半导体器件领域具有重大指导意义.

关键词：绝缘栅双极晶体管积累模式正向导通压降关断损耗

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Chinese Chemical Letters 2024年第1期35卷 499-504页

作者： Saisai Yuan Yu Zhou Tengyang Gao Lichuan Chen Wei Xu Ping duan Juejun Wang Zhichao Pan chun Tang Yang Yang Ruiyun Huang Zongyuan Xiao Wenjing Hong State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China

Folding of molecules is an essential process in nature,and various molecular machines achieve their chemical and mechanical function via controlled folding of molecular *** electric field offers a unique strategy to drive the folding of molecular conformation and to control charge transport through single molecules but remains *** single-molecule break junction technique provides access to detect the conformational changes via the monitoring of single-molecule conductance,and the electric field between two metal electrodes with nanoscale spacing can provide an extremely strong to achieve in-situ control and detection of molecular folding at the single-molecule ***,we use the electric field to control the single-molecule folding using the scanning tunneling microscope break junction(STM-BJ)*** electric fields induced folding could lead to a∼1400%conductance change of the single-molecule junctions,and the folding/unfolding process can be in-situ switched at the scale of *** calculations suggest the conformational control originates from the electric fieldinduced charge injection,and the formation of homoconjugated conformation with the overlapped *** work provides the first demonstration of electric field-driven molecular folding,which is essential for the understanding of molecular machines in nature and for the design of artificial molecular machines.

关键词： Electric field Single-molecule Break junction Molecular folding In-situ switch

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石灰石—石膏法烟气脱硫技术转型升级的探讨

硫磷设计与粉体工程 2024年第4期181卷 1-3,27,I0001页

作者：段付岗宁夏泰丰铂尊新材料科技有限公司宁夏银川750411

由于传统石灰石—石膏法烟气脱硫会产生工业废渣硫石膏并产生CO 2废气,背离了“十四·五”规划提出的双碳目标,不符合生态环保、低碳减排、资源利用、循环经济、可持续发展的国家战略规划。从产品改型、环境保护和资源利用等方面,分析... 详细信息

由于传统石灰石—石膏法烟气脱硫会产生工业废渣硫石膏并产生CO 2废气,背离了“十四·五”规划提出的双碳目标,不符合生态环保、低碳减排、资源利用、循环经济、可持续发展的国家战略规划。从产品改型、环境保护和资源利用等方面,分析了石灰石—石膏法烟气脱硫技术转型升级的必要性,提出将其转型升级为氨—硫酸铵法脱硫技术和磷矿石—磷酸—磷石膏法脱硫技术,并针对不同的改造方案提出了具体改造措施及建议。

关键词：烟气脱硫石灰石—石膏法技术转型产品改型氨法脱硫磷矿石法脱硫措施

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光伏桩基用钢在新疆土壤中的腐蚀行为研究

中国腐蚀与防护学报 2024年第4期44卷 987-992页

作者：王刚李昭王涛段腾杜翠薇特变电工新疆新能源股份有限公司乌鲁木齐830011 北京科技大学新材料技术研究院北京100083

采用扫描电镜(SEM)、能谱(EDS)以及X射线衍射(XRD)等技术对比分析了新疆某地区不同光伏桩基用钢在现场土壤及室内土壤加速环境下的腐蚀形貌及腐蚀产物,并且结合电化学实验对比研究了不同光伏桩基用钢在新疆土壤环境中的腐蚀行为。结果表... 详细信息

采用扫描电镜(SEM)、能谱(EDS)以及X射线衍射(XRD)等技术对比分析了新疆某地区不同光伏桩基用钢在现场土壤及室内土壤加速环境下的腐蚀形貌及腐蚀产物,并且结合电化学实验对比研究了不同光伏桩基用钢在新疆土壤环境中的腐蚀行为。结果表明,对比其他两种耐蚀钢,Q355B普碳钢的腐蚀情况最严重;腐蚀产物主要为Fe的氧化物,包括α-FeOOH和γ-FeOOH;3种材料在相同的室内加速腐蚀条件下具有相同的加速比,其腐蚀机理与现场试样基本一致。

关键词： Q355B普碳钢耐蚀钢土壤腐蚀加速腐蚀实验光伏桩