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Performance of FAST with an Ultra-Wide Bandwidth Receiver at 500–3300 MHz

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Research in Astronomy and Astrophysics 2023年第7期23卷 197-205页

作者： Chuan-Peng Zhang Peng Jiang Ming Zhu Jun Pan Cheng Cheng Hong-Fei Liu Yan Zhu chun Sun FAST Collaboration National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Guizhou Radio Astronomical Observatory Guizhou UniversityGuiyang 550000China College of Earth Sciences Guilin University of TechnologyGuilin 541004China

The Five-hundred-meter Aperture Spherical radio Telescope(FAST)has been running for several years.A new ultra-wide bandwidth(UWB)receiver,simultaneously covering 500-3300 MHz,has been mounted in the FAST feed cabin and has passed a series of observational *** whole UWB band is separated into four independent *** band has 1,048,576 channels in total,resulting in a spectral resolution of 1 *** 500-3300 MHz,the antenna gain is around 14.3-7.7 K Jy^(-1),the aperture efficiency is around 0.56-0.30,the system temperature is around 88-130 K,and the half-power beamwidth is around 7.6'-1.6'.The measured standard deviation of pointing accuracy is better than~7.9"when zenith angle is within 26.4°.The sensitivity and stability of the UWB receiver are confirmed to satisfy expectations through spectral observations,e.g.,hi and *** FAST UWB receiver has already demonstrated good performance in capturing sensitive observations for various scientific goals.

关键词： instrumentation:detectors telescopes line:profiles

Current status of intragastric balloon for obesity treatment

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World Journal of Gastroenterology 2016年第24期22卷 5495-5504页

作者： Seung Han Kim Hoon Jai chun Hyuk Soon Choi Eun Sun Kim Bora Keum Yoon Tae Jeen Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointestinal Medical Instrument Research Korea University College of Medicine

Endoscopic bariatric therapy may be a useful alternative to pharmacological treatment for obesity, and it provides greater efficacy with lower risks than do conventional surgical procedures. Among the various endoscopic treatments for obesity, the intragastric balloon is associated with significant efficacy in body weight reduction and relief of comorbid disease symptoms. Anatomically, this treatment is based on gastric space-occupying effects that increase the feeling of satiety and may also affect gut neuroendocrine signaling. The simplicity of the intragastric balloon procedure may account for its widespread role in obesity treatment and its applicability to various degrees of obesity. However, advances in device properties and procedural techniques are still needed in order to improve its safety and cost-effectiveness. Furthermore, verification of the physiological outcomes of intragastric balloon treatment and the clinical predictive factors for treatment responses should be considered. In this article, we discuss the types, efficacy, safety, and future directions of intragastric balloon treatment.

关键词： Intragastric balloon Obesity Bariatric Metabolic Endoscopy

Suppression of Multiples by Improved Expanding Multi-Channel Match Minus Method

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石油地球物理勘探 2009年第3期44卷 52-58页

作者： Liu Hua-Feng Li Qing-chun Wang Li-Ming Key Lab of Geophysical Exploration of CNPC China University of Petroleum (Beijing) Beijing 102249 China Key Lab of Western Geological Resources and Engineering of Education Ministry Chang'an University Xi'an 710054 China

本文采用基于时差方程的多次波预测方法预测多次波模型记录,结合单道匹配、常规多道匹配、伪多道匹配和扩展多道匹配四种相减方法的优缺点,给出了改进的多道匹配相减方法和改进的扩展多道匹配相减方法的计算步骤,并尝试在匹配相减方法... 详细信息

本文采用基于时差方程的多次波预测方法预测多次波模型记录,结合单道匹配、常规多道匹配、伪多道匹配和扩展多道匹配四种相减方法的优缺点,给出了改进的多道匹配相减方法和改进的扩展多道匹配相减方法的计算步骤,并尝试在匹配相减方法中评估迭代思想的作用.通过理论模型和实测资料的测试,得出了以下主要结论:①在已知水层深度这一先验信息的前提下,利用时差方程方法预测多次波模型记录,计算速度快,精度基本满足要求,是一种预测海底多次波的有效方法;②改进的扩展多道匹配相减方法适应能力较强,具有较好的信号保真度,在模型测试和实际数据应用中,均取得了较为满意的效果,并可与其他预测方法搭配使用;③滤波因子长度、时窗大小和相邻匹配道数这三个主要控制参数,对匹配相减的效果有影响,在应用匹配相减方法时,需要针对数据本身的特点,选择合适的匹配参数.经过对比迭代匹配相减的结果发现,迭代运算对于提高匹配精度的作用不大.

关键词：相匹配多通道预测模型镇压乘数计算速度深度信息测试数据

Gut mucosal microbiota profiles linked to colorectal cancer recurrence

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World Journal of Gastroenterology 2022年第18期28卷 1946-1964页

作者： Rui-Xue Huo Yi-Jia Wang Shao-Bin Hou Wei Wang chun-Ze Zhang Xue-Hua Wan Department of Oncology Tianjin Union Medical CenterNankai UniversityTianjin 300121China Laboratory of Oncologic Molecular Medicine Tianjin Union Medical CenterNankai UniversityTianjin 300121China Advanced Studies in Genomics Proteomics and BioinformaticsUniversity of Hawaii at ManoaHonoluluHI 96822United States TEDA Institute of Biological Sciences and Biotechnology Nankai UniversityTianjin 300457China Department of Colorectal Surgery Tianjin Union Medical CenterNankai UniversityTianjin 300121China Tianjin Institute of Coloproctology Tianjin 300121China

BACKGROUND Emerging evidence links gut microbiota to various human diseases including colorectal cancer(CRC)initiation and ***,gut microbiota profiles associated with CRC recurrence and patient prognosis are not completely understood yet,especially in a Chinese *** To investigate the relationship between gut mucosal microbiota profiles and CRC recurrence and patient *** We obtained the composition and structure of gut microbiota collected from 75 patients diagnosed with CRC and 26 healthy *** patients were followed up by regular examination to determine whether tumors ***-paired samples from on-tumor,adjacent-tumor and off-tumor sites of patients diagnosed with/without CRC recurrence were analyzed to assess spatial-specific patterns of gut mucosal microbiota by 16S ribosomal RNA ***,we carried out bioinformatic analyses,Kaplan-Meier survival analyses and Cox regression analyses to determine the relationship between gut mucosal microbiota profiles and CRC recurrence and patient *** We observed spatial-specific patterns of gut mucosal microbiota profiles linked to CRC recurrence and patient prognosis.A total of 17 bacterial genera/families were identified as potential biomarkers for CRC recurrence and patient prognosis,including Anaerotruncus,Bacteroidales,Coriobacteriaceae,Dialister,Eubacterium,Fusobacterium,Filifactor,Gemella,Haemophilus,Mogibacteriazeae,Pyramidobacter,Parvimonas,Porphyromonadaceae,Slackia,Schwartzia,TG5 and *** Our work suggests that intestinal microbiota can serve as biomarkers to predict the risk of CRC recurrence and patient death.

关键词： Gut microbiota Colorectal cancer Prognosis Colorectal cancer recurrence Biomarker 16S rRNA sequencing analysis

南黄海B10岩心的地球化学特征及其对古环境和古气候的反映

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海洋学报 2003年第1期25卷 69-77页

作者：陈志华石学法王湘芹辛春英孔繁荣 YI hi-Il 国家海洋局第一海洋研究所青岛海洋大学海洋地球科学学院山东青岛266003 韩国海洋研究所

通过对南黄海中部B10岩心的碳酸钙、常量元素和微量元素分析发现,岩心的地球化学特征基本反映了该海区晚第四纪气候变化、海面波动以及沉积物供应的变化.在玉木亚间冰期(末次冰期亚间冰期)高海面时期,黄河可能直接注入南黄海,在南黄海... 详细信息

通过对南黄海中部B10岩心的碳酸钙、常量元素和微量元素分析发现,岩心的地球化学特征基本反映了该海区晚第四纪气候变化、海面波动以及沉积物供应的变化.在玉木亚间冰期(末次冰期亚间冰期)高海面时期,黄河可能直接注入南黄海,在南黄海中部发育水下三角洲沉积.晚玉木冰期(末次冰期盛冰期),南黄海出露成陆,局部发育陆相泥炭层.冰后期(全新世)海侵到达现今80 m等深线附近的时间大约在距今13 ka。在距今11.0～10.3 ka出现新仙女木事件.全新世中晚期海面进一步上升,沉积物粒度较细,化学风化作用加强.岩心50～0 cm段沉积物中的碳酸钙、氧化钙、锶、氧化镁含量及Sr/Ba比值低,而铜等微量元素含量增加,这可能与公元1855年黄河北迁后进入南黄海中部的黄河物质减少有关.

关键词：晚第四纪地球化学古环境古气候甫黄海碳酸钙常量元素微量元素海洋沉积物

The parallel tetrameric DNA G-quadruplex formed by the two-repeat C9orf72 GGGGCC sequence in solution Dedicated to Professor Chaohui Ye on the occasion of his 80th birthday

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Magnetic Resonance Letters 2022年第4期2卷 196-204页

作者： Changdong Liu Bo Zhou Naining Xu chun Po Fung Bing Yan Monica Ching Suen Zeguo Huang Guang Zhu Division of Life Science The Hong Kong University of Science and TechnologyClear Water BayKowloonHong Kong SAR00000China HKUST Shenzhen Research Institute Hi-Tech ParkNanshanShenzhen518057China Department of Oral and Maxillofacial Surgery Stomatological CenterPeking University Shenzhen HospitalShenzhen Peking University-The Hong Kong University of Science and Technology Medical CenterShenzhen518036China Hong Kong Branch of Guangdong Southern Marine Science and Engineering Laboratory(Guangzhou) Hong Kong University of Science and TechnologyClear Water BayKowloonHong Kong SAR00000China State Key Laboratory of Molecular Neuroscience The Hong Kong University of Science and TechnologyClear Water BayKowloonHong Kong SAR00000China

The abnormal expansion of G-rich hexanucleotide repeat,GGGGCC(G4C2),in chromosome 9 open reading frame 72(C9orf72)is known to be the prevailing genetic cause of two fatal degenerative neurological diseases,amyotrophic lateral sclerosis(ALS)and frontotemporal dementia(FTD).It is well known that the DNA G4C2 repeat expansion with different lengths can form G-quadruplexes which affect gene transcription related to ALS/FTD,therefore it is crucial to understand DNA G4C2 G-quadruplex ***,by utilizing nuclear magnetic resonance(NMR)spectroscopy,we examined DNA G-quadruplex structure adopted by two G4C2 hexanucleotide repeats with an inosine substitution at position 4,d(G4C2)*** show that d(G4C2)2-I4 folds into an eight-layer parallel tetrameric G-quadruplex containing two parallel dimeric G-quadruplexes stacking together through p-p interaction via 50-to-50 mode in *** dimeric G-quadruplex unit involves two propeller loops composed of two cytosine *** result is consistent with the observation in the crystal structure of d(G4C2)*** work not only sheds light on the structural diversity of G-quadruplexes adopted by d(G4C2)n but also provides a structural basis for drug design in treatment of ALS and FTD.

关键词： Hexanucleotide repeat G4C2 expansion G-quadruplex Amyotrophic lateral sclerosis(ALS) Frontotemporal dementia(FTD) Nuclear magnetic resonance(NMR)

Surface finish of micro punch with ion beam irradiation

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Transactions of Nonferrous Metals Society of China 2009年第S2期19卷 526-530页

作者： XU Jie WANG chun-ju GUO Bin SHAN De-bin Y.SUGIYAMA S.ONO School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China Key Laboratory of Micro-Systems and Micro-Structures Manufacturing Ministry of EducationHarbin Institute of TechnologyHarbin 150080China Elionix Inc. Tokyo 192-0063Japan

Ion beam irradiation was adopted for surface treatment of the micro punch manufactured by precision *** plasma was used for the ion irradiation process,which was generated by the electron cyclotron resonance(ECR)*** surface finish processes of micro punch were carried out at irradiation angles of 45°and 10°,*** surface roughness and topography were measured to estimate the quality of surface *** results show that the ion irradiation is very effective to reduce the surface roughness,which can be improved more significantly at irradiation angle of 10°than at 45°.The technology of surface finish with ion beam irradiation is suitable for the surface treatment of micro die.

关键词： surface finish ion beam micro punch surface roughness

A Comparative miRNAome Analysis Reveals Seven Fiber Initiation-Related and 36 Novel miRNAs in Developing Cotton Ovules

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Molecular Plant 2012年第4期5卷 889-900页

作者： Zheng-Ming Wang Wei Xue chun-Juan Dong Long-Guo Jin Shao-Min Bian Chuan Wang Xiu-Yun Wu Jin-Yuan Liu Laboratory of Molecular Biology and MOE Laboratory of Protein Science School of Life SciencesTsinghua UniversityBeijing 100084China

An increasing number of microRNAs （miRNAs） have been shown to play crucial regulatory roles in the process of plant development. Here, we used high-throughput sequencing combined with computational analysis to characterize miRNAomes from the ovules of wild-type upland cotton and a fiberless mutant during fiber initiation. Comparative miR- NAome analysis combined with northern blotting and RACE-PCR revealed seven fiber initiation-related miRNAs expressed in cotton ovules and experimentally validated targets of these miRNAs are involved in different cellular responses and metabolic processes, including transcriptional regulation, auxin and gibberellin signal transduction, actin bundles, and lignin biosynthesis. This paper describes a complex regulatory network consisting of these miRNAs expressed in cotton ovules to coordinate fiber initiation responses. In addition, 36 novel miRNAs and two conserved miRNAs were newly iden- tified, nearly doubling the number of known cotton miRNA families to a total of 78. Furthermore, a chromatin remodeling complex subunit and a pre-mRNA splicing factor are shown for the first time to be miRNA targets. To our knowledge, this study is the first systematic investigation of fiber initiation-related miRNAs and their targets in the developing cotton ovule, deepening our understanding of the important regulatory functions of miRNAs in cotton fiber initiation.

关键词： Cotton ovules fiber initiation high-throughput sequencing molecular characterization newly identifiedmiRNAs.

Whole-genome sequencing of leopard coral grouper(Plectropomus leopardus) and exploration of regulation mechanism of skin color and adaptive evolution

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Zoological Research 2020年第3期41卷 328-340页

作者： Yang Yang Li-Na Wu Jing-Fang Chen Xi Wu Jun-Hong Xia Zi-Ning Meng Xiao-chun Liu Hao-Ran Lin State Key Laboratory of Biocontrol Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic AnimalsLife Sciences SchoolSun Yat-Sen UniversityGuangzhouGuangdong 510275China State Key Laboratory of Biocontrol and Guangdong Provincial Key Laboratory of Plant Resources School of Life SciencesSun Yat-Sen UniversityGuangzhouGuangdong 510275China Southern Laboratory of Ocean Science and Engineering ZhuhaiGuangdong 519000China

Leopard coral groupers belong to the Plectropomus genus of the Epinephelidae family and are important fish for coral reef ecosystems and the marine aquaculture industry. To promote future research of this species, a high-quality chromosome-level genome was assembled using PacBio sequencing and hi-C technology. A 787.06 Mb genome was assembled, with 99.7%(784.57 Mb) of bases anchored to 24 chromosomes. The leopard coral grouper genome size was smaller than that of other groupers, which may be related to its ancient status among grouper species. A total of 22 317 proteincoding genes were predicted. This high-quality genome of the leopard coral grouper is the first genomic resource for Plectropomus and should provide a pivotal genetic foundation for further research. Phylogenetic analysis of the leopard coral grouper and 12 other fish species showed that this fish is closely related to the brown-marbled *** genes in the leopard coral grouper genome were mainly associated with immune response and movement ability, which may be related to the adaptive evolution of this species to its habitat. In addition, we also identified differentially expressed genes(DEGs) associated with carotenoid metabolism between red and brown-colored leopard coral groupers. These genes may play roles in skin color decision by regulating carotenoid content in these groupers.

关键词： Leopard coral grouper Genome Evolution Skin color Immune