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The ethical dilemma of placebo use in clinical practice

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Frontiers of Nursing 2020年第3期7卷 203-208页

作者： chun-yi xu chun-Ming Yuan Department of Orthopedics Sichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalChengduSichuan 610000China

The clinical use of placebo that involves some ethical issues has led to much *** the standpoint of both supporters and opponents,this article discusses this topic from three ethical principles such as beneficence,justice,and autonomy and also gives the ***,the moral dilemma caused by the different views between nurses and doctors in clinical practice is discussed.

关键词： placebo ethical dilemma moral distress

Rehabilitation nursing for an earthquake survivor with severe polytrauma:A case report and literature review

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Journal of Integrative Nursing 2020年第3期2卷 149-152页

作者： chun‑yi xu Fang TANG Department of Orthopedic Sichuan Academy of Medical Sciences and Sichuan Provincial People’s HospitalChengduChina

The aim of this article is to summarize the experience of rehabilitation nursing of one case of severe polytrauma caused by *** key points of the rehabilitation nursing include body posture nursing,orthopedic rehabilitation nursing,pulmonary function rehabilitation nursing,bladder rehabilitation nursing,nutritional support,and psychological rehabilitation *** the comprehensive rehabilitation nursing interventions,satisfactory outcomes were obtained,and the patient was successfully recovered and discharged after 2 months.

关键词： Earthquake polytrauma rehabilitation nursing

Roles of MT-ND1 in Cancer

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Current Medical Science 2023年第5期43卷 869-878页

作者： yi-chun xu Jun SU Jia-jing ZHOU Qing YUAN Jun-song HAN Department of Pathology Shanghai Tongji HospitalTongji Hospital Affiliated to Tongji UniversityShanghai 200065China National Engineering Research Center for Biochip Shanghai Biochip Limited CorporationShanghai 201203China

The energy shift toward glycolysis is one of the hallmarks of *** I is a vital enzyme complex necessary for oxidative *** mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1(MT-ND1)is the largest subunit coded by mitochondria of complex *** present study summarizes the structure and biological function of *** databases and literature,the expressions and mutations of MT-ND1 in a variety of cancers have been ***-ND1 may be a biomarker for cancer diagnosis and *** is also a potential target for cancer therapy.

关键词： mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 cancer biomarker mutation

Isolating Ships from Shape Curve with DBSCAN

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Isolating Ships from Shape Curve with DBSCAN

Interaction of radiation-induced defects with tungsten grain boundaries at across scales: a short review

第25届中国控制与决策会议

作者： yi-chun xu Man Zhu Zunhai Ke Yong Liu Suifa Sun Computer and Information College China Three Gorges University

ISBN: (纸本)9781467355339

This paper proposes a video surveillance system to position ships in a ship lock. A background subtraction method is employed to extract the foreground of all ships. Subsequently, the DBSCAN clustering algorithm is applied to isolate each ship from the curves scanned from the extracted foreground regions. The system can locate adjacent ships and identify each one in real time. Theoretical analyses and ex periments show that the performance of the whole system depends on the quality of the foreground extraction. A robust backgrounds subtrac tion method can bring improved system performance.

关键词： Object Detection Image Segmentation Background Subtraction DBSCAN Video Surveillance

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Tungsten 2020年第1期2卷 15-33页

作者： Xiang‑Yan Li Yan‑Ge Zhang yi‑chun xu xue‑Bang Wu Xiang‑Shan Kong Xian‑Ping Wang Qian‑Feng Fang Chang‑Song Liu Key Laboratory of Materials Physics Institute of Solid State PhysicsChinese Academy of SciencesHefei 230031China Key Laboratory for Liquid‑Solid Structural Evolution and Processing of Materials(Ministry of Education) Shandong UniversityJinan 250061China

As promising candidates for plasma-facing materials,tungsten-based materials suffer the irradiation of high-energy neutrons in addition to the hydrogen isotopes and helium irradiation and the high-thermal ***-produced defects,***-interstitial atoms(SIAs)and vacancies(Vs),can induce the hardening and embrittlement of tungsten,meanwhile enhancing the retention of hydrogen isotopes and helium in *** the grain size of materials to introduce a high density of defect sinks,e.g.,grain boundaries(GBs)prevalent in nano-/ultrafine-crystalline materials,was demonstrated to be an effective approach for mitigating irradiation damage in *** this paper,we reviewed the theoretical advances in exploring radiation-resistance of nano-structured tungsten at across *** was concentrated on the results of molecular dynamics,molecular statics,and the object kinetic Monte Carlo simulations on the fundamental interaction of the radiation-created Vs and SIAs with the *** mechanisms include GB-promoted V/SIA migration and SIA-V recombination,interstitial-emission induced annihilation,coupling of the V migration close to the GB with the SIA motion within the GB,and interstitial reflection by the locally dense GB *** proposed the remaining scientific issues on the defect-GB interactions at across scales and their relation to experimental *** prospected the possible trends for simulating the radiation damage accumulation and healing processes in nano-structured tungsten in terms of the development of the across-scale computational techniques and efficiency of the GB-enhanced tolerance of tungsten to irradiation under complex in-service conditions.

关键词： Nano-crystalline Grain boundary Radiation-resistance Self-healing Radiation damage Tungsten

A deep learning interatomic potential suitable for simulating radiation damage in bulk tungsten

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Tungsten 2024年第2期6卷 304-322页

作者： Chang-Jie Ding Ya-Wei Lei Xiao-Yang Wang Xiao-Lin Li Xiang-Yan Li Yan-Ge Zhang yi-chun xu Chang-Song Liu xue-Bang Wu Key Laboratory of Materials Physics Institute of Solid State PhysicsHFIPSChinese Academy of SciencesHefei 230031China Science Island University of Science and Technology of ChinaHefei 230026China Laboratory of Computational Physics Institute of Applied Physics and Computational MathematicsBeijing 100088China

So far, it has been a challenge for existing interatomic potentials to accurately describe a wide range of physical properties and maintain reasonable efficiency. In this work, we develop an interatomic potential for simulating radiation damage in body-centered cubic tungsten by employing deep potential, a neural network-based deep learning model for representing the potential energy surface. The resulting potential predicts a variety of physical properties consistent with first-principles calculations, including phonon spectrum, thermal expansion, generalized stacking fault energies, energetics of free surfaces, point defects, vacancy clusters, and prismatic dislocation loops. Specifically, we investigated the elasticity-related properties of prismatic dislocation loops, i.e., their dipole tensors, relaxation volumes, and elastic interaction energies. This potential is found to predict the maximal elastic interaction energy between two 1/2 loops better than previous potentials, with a relative error of only 7.6%. The predicted threshold displacement energies are in reasonable agreement with experimental results, with an average of 128 eV. The efficiency of the present potential is also comparable to the tabulated gaussian approximation potentials and modified embedded atom method potentials, meanwhile, can be further accelerated by graphical processing units. Extensive benchmark tests indicate that this potential has a relatively good balance between accuracy, transferability, and efficiency.

关键词： Machine learning Deep learning Interatomic potential Radiation damage Tungsten

Trends of alkaline phosphatase to prealbumin ratio in patients with hepatitis B linked to hepatocellular carcinoma development

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World Journal of Gastroenterology 2025年第2期31卷 42-51页

作者： Wen-Chong Zhen Jing Sun xue-Ting Bai Qian Zhang Zi-Han Li yi-Xin Zhang Rong-xuan xu Wei Wu Zhi-Han Yao chun-Wen Pu Xiao-Feng Li School of Public Health Dalian Medical UniversityDalian 116044Liaoning ProvinceChina Graduate School Dalian Medical UniversityDalian 116044Liaoning ProvinceChina Dalian Public Health Clinical Center Dalian Municipal Research Institute for Public HealthDalian 116001Liaoning ProvinceChina Department of Epidemiology and Health Statistics Dalian Medical UniversityDalian 116044Liaoning ProvinceChina

BACKGROUND Chronic hepatitis B often progresses silently toward hepatocellular carcinoma(HCC),a leading cause of mortality *** detection of HCC is crucial,yet *** To investigate the role of dynamic changes in alkaline phosphatase to prealbumin ratio(APR)in hepatitis B progression to *** Data from 4843 patients with hepatitis B(January 2015 to January 2024)were *** incidence rates in males and females were compared using the log-rank *** were evaluated using Kaplan–Meier *** Linear Mixed-Effects Model was applied to track the fluctuation of APR levels over ***,Joint Modeling of Longitudinal and Survival data was employed to investigate the temporal relationship between APR and HCC *** The incidence of HCC was higher in *** ensure the model’s normality assumption,this study applied a logarithmic transformation to APR,yielding *** levels were higher in females(t=5.26,P<0.01).A 1-unit increase in ratio correlated with a 2.005-fold higher risk of HCC in males(95%CI:1.653-2.431)and a 2.273-fold higher risk in females(95%CI:1.620-3.190).CONCLUSION Males are more prone to HCC,while females have higher APR *** no baseline APR link,rising APR indicates a higher HCC risk.

关键词： Alkaline phosphatase to prealbumin ratio Chronic hepatitis B patients Hepatocellular carcinoma Retrospective cohort study Linear Mixed-Effect Mode Joint Modelling of Longitudinal and Survival data

Concept analysis of nurse burnout

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The ethical dilemma of placebo use in clinical practice

Frontiers of Nursing 2020年第3期

作者： chun-Ming Yuan chun-yi xu

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