检索结果-南通市图书馆

Acta Pharmacologica Sinica 2005年第12期26卷 1485-1491页

作者： chuan wang xiao-na du qing-zhong jia hai-lin zhang~2 department of pharmacology hebei medical university,shijiazhuang 050017,china department of pharmacology Hebei Medical University Shijiazhuang China

Aim:To investigate the effects of the pleckstrin homology(PH)domain of phos-pholipase Cδ1(PLCδ1PH)on inhibition of phospholipase C(PLC)-mediated hy-drolysis of phosphatidylinositol 4,5-bisphosphate[PtdIns(4,5)P2]by ***:A fusion construct of green fluorescent protein(GFP)and PLCδ1PH(PLCδ1PH-GFP),which is known to bind PtdIns(4,5)P2specifically,together withlaser-scanning confocal microscopy,was used to trace PtdIns(4,5)***:Stimulation of the type 1 muscarinic receptor and the bradykinin 2 recep-tor induced a reversible PLCδ1PH-GFP translocation from the membrane to thecytosol in COS-7 *** inhibitor U73122 blocked the ***,a known PtdIns kinase inhibitor,did not affect the translocationinduced by ACh,but blocked recovery after translocation,indicating thatPtdIns(4,5)P2hydrolysis occurs through receptor-mediated PLC ***,a commonly used phospholipase C blocker,failed to block the recep-tor-induced PLCδ1PH-GFP translocation,indicating that neomycin is unable toblock PLC-mediated Ptdlns(4,5)Pe ***,in the absence of PLCδ1PH-GFP expression,neomycin abolished the receptor-induced hydrolysis ofPtdIns(4,5)P2 by ***:Although PLCδ1PH and neomycin bind toPtdIns(4,5)P2 in a similar way,they have distinct effects on receptor-mediatedactivation of PLC and PtdIns(4,5)P2 hydrolysis.

关键词： phosphatidylinositol 4,5-bisphosphate neomycin phospholipase C pleckstrin homology domains competitive binding acetylcholine green fluorescent proteins

Kv7 (KCNQ) potassium channels and related diseases

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Kv7 (KCNQ) potassium channels and related diseases

中国药理学会第十一次全国学术会议

作者： SHI Wen-jing,jia qing-zhong (department of pharmacology,hebei medical university,shijiazhuang 050017,china)

Kv7 channels which encoded with KCNQ genes(KCNQ1 -5) are a small family of voltage-gated potassium channel, while impressively with critical roles in physiology and *** of KCNQ channels and KCNQ gene mutations have been identified to cause a lot of diseases and genetic *** QT syndrome,a disorder of cardiac repolarisation,of which the most common form,LQT1 is related to KCNQ1 mutation or co-expression of mutant KCNE1 with *** familial neonatal convulsions (BFNCs) were reported to be caused by the mutations of brain KCNQ2 and KCNQ2/3 *** hearing loss can be associated with Jervell and Lange-Nielsen(JLN) syndrome(one form of LQT1) and mutations in the KCNE1 and KCNQ1(co ex- pressed in the cell of stria vascularis) or the KCNQ4(expressed in outer hair cells) ***5 is expressed in skeletal muscle and *** co-assembled with KCNQ3,it plays a role in the M-current ***7 channels also play newly identified physiological roles in vascular system that attracts increased *** of KCNQ channels have the potential to influence neuronal activity in various tissues and are of much interest as therapeutic drug targets for the treatment of a variety of clinical disorders as epilepsy, convulsion,stroke,Alzheimer’s disease,pain,***,the function of KCNQ channels,expressions and mutations of KCNQ genes have been a subject of increasing interest during the last decade.

关键词： KCNQ mutation epilepsy LQT hereditary disorders

The regulation of KCNQ2/3 potassium channel by EGFR

在线全文

cnki会议

学校读者我要写书评

暂无评论

The regulation of KCNQ2/3 potassium channel by EGFR

中国神经科学学会第六届学术会议暨学会成立十周年庆祝大会

作者： jia qing-zhong, du xiao-na, jia Zhan-feng, Liu Bo-yi, zhang hai-lin department of pharmacology, Heibei medical university, shijiazhuang, 050017, china

＜正＞Objective: To observe the effect of EGFR activation on KCNQ2/3 potassium channel and explore the mechanism of regulation. Methods: The KCNQ2 and KCNQ3 potassium channel were co- expressed in HEK293 cell using Lipofectamine kits （Invitrogen）. Whole-cell patch clamp recordings were made from HEK293 cell. The laser confocal microscopy technique was used to monitor the changes of membrane PIP2, PIP3 and intracellular Ca2+. Results: （1）KCNQ2/3 currents were inhibited by long incubation with EGF in HEK293 cells. HEK293 cells expressing KCNQ2/3 channels were pre-incubated with EGF（100ng/ml） for 30 min. The KCNQ2/3 currents elicited from these cells were inhibited significantly;the amplitude of the currents was decreased to 28%±9.2% （n=5, P＜0.01）;the half activation voltage was shifted from （-16.6±1.2）mV to （-13.5±1.5）mV;the activation and deactivation kinetic processes were slowed. （2）A tyrosine phosphatase inhibitor vanadate （100μmol/l） mimicked EGF actions and decreased the KCNQ2/3 current to 45%±12.8% （n=5, P＜0.01）;the time constant of activation and deactivation were prolonged from （230±37）ms, （130±28）ms to （535±42）ms, （358±39）ms, respectively.

关键词： KCNQ EGFR regulation

The regulation of KCNQ2/3 potassium channel by extracelluar K+ and pH

在线全文

cnki会议

学校读者我要写书评

暂无评论

The regulation of KCNQ2/3 potassium channel by extracelluar ...

中国神经科学学会第六届学术会议暨学会成立十周年庆祝大会

作者： jia qing-zhong, Liu Bo-yi, jia Zhan-feng, du xiao-na, zhang hai-lin department of pharmacology, Heibei medical university, shijiazhuang 050017, china

＜正＞Aim: To observe the effect of extracelluar of K+ and pH on KCNQ2/3 potassium current and explore the mechanism of regulation. Methods: The cRnas of KCNQ were prepared using RibomaxTM Large Scale Rna Production Systems-SP6 and T7 Kit. Xenopus Oocytes injected with the cRna of KCNQ2 and KCNQ3 potassium channel by 1:1 ratio were cultured in ND96 solution for 2-3 d. Whole cell KCNQ currents were recorded using TEVC method and to observe the effect of different concentrations of K+ and H+ solutions. Results: （1）The amplitude of KCNQ2/3 current was enhanced by extracellular K+ in concentration-dependent manner. Elevation of external [K+] at a range of 0-15mmol/L potentiated KCNQ2/3 and KCNQ2 currents, and the effect of external [K+] was more significant on KCNQ2 currents than KCNQ2/3 currents. （2） Elevation of extracellular [K+] had obvious effect on the slope of KCNQ2/3 channel’s activation curve. When extracellular [K+] was changed from 0 and 12mmol/L, the initial potential of activation was not changed （-60mV）, and the half activation voltage was shifted slightly to

关键词： KCNQ K+ pH regulation

Modulation of KCNQ potassium channels by a novel opener pyrazolo[l,5-a]pyrimidin-7(4H)-one compound QO-58

在线全文

cnki会议

学校读者我要写书评

暂无评论

Modulation of KCNQ potassium channels by a novel opener pyra...

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Fan zhang,Jing-Jing MA,Yi MI,Jin-Long QI,qing-zhong jia,xiao-na du,hai-lin zhang 1 department of pharmacology,2 department of New Drug Development,hebei medical university,shijiazhuang 050017,china

Voltage-gated Kv7/KCNQ/M-potassium channels play an essential role in setting the resting membrane potential and in controlling the excitability of *** or depression of KCNQ channels results in neuronal hyperactivity and *** function is also indicated in nociceptive sensory ***,modulation of KCNQ2/3 function represents a potentially new strategy to treat neuronal excitability disorders such as epilepsy and neuropathic *** designed and synthesized a novel serial compounds of pyrazolo[1,5-a]pyrimidin-7(4H)- ones(PPOs)which activate KCNQ ***,in this study,we characterized one of these compounds,QO- 58’s effect and mechanism underlying the activation of KCNQ channels using patch clamp technique.(1)QO-58 activated KCNQ2/Q3 currents at-40 mV concentration-dependently with a ECof 2.3±0.8μM.(2)QO-58 shifted the voltage-dependent activation of the KCNQ2/Q3 channel,and the Vwas shifted approximately-40 mV towards more negative potential in the presence 10 uM QO-58.(3)QO-58 significantly slowed channel activation and deactivation kinetics.(4)Among KCNQ channels,QO-58 increased homomeric KCNQ1-4 and heteromeric KCNQ3/Q5 currents recorded at-40 mV;The ECs value were 7.05±1.0,1.31±1.0,9.70±2.4,0.60±0.1,5.16±2.2μM,for KCNQ1, KCNQ2,KCNQ3,KCNQ4 and KCNQ3/Q5,respectively.(5)QO-58 enhanced native M currents from rat DRG neurons.(6)QO-58 dose-dependently prevented seizures induced by electroshock in rats,with a 73.3%reduction of seizures obtained at a dose of 50 mg/*** results indicate QO-58 is a potent KCNQ channel opener with more selective effect on KCNQ2 and ***-58 activates KCNQ channels through enhancing voltage-dependent activation and slowing channel ***-58 shows potent anti-seizure effects and can be developed further to treat disease related with neuronal hyperexcitability.

关键词： KCNQ channels M channel opener QO-58 seizures

Transarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma(CHANCE001)

在线全文

cnki会议

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2023年第3期8卷 1198-1207页

作者： hai-Dong Zhu hai-Liang Li Ming-Sheng Huang Wei-Zhu Yang Guo-Wen Yin Bin-Yan zhong Jun-Hui Sun Zhi-Cheng Jin jian-jian Chen nai-jian Ge Wen-Bin Ding Wen-Hui Li Jin-Hua Huang Wei Mu Shan-Zhi Gu jia-Ping Li Hui Zhao Shu-Wei Wen Yan-Ming Lei Yu-Sheng Song Chun-wang Yuan Wei-Dong wang Ming Huang Wei Zhao jian-Bing Wu Song wang Xu Zhu jian-Jun Han Wei-Xin Ren Zai-Ming Lu Wen-Ge Xing Yong Fan hai-Lan lin Zi-Shu zhang Guo-Hui Xu Wen-Hao Hu Qiang Tu Hong-Ying Su chuan-Sheng Zheng Yong Chen Xu-Ya Zhao Zhu-Ting Fang Qi wang Jin-Wei Zhao Ai-Bing Xu jian Xu qing-Hua Wu Huan-zhang Niu jian wang Feng Dai dui-Ping Feng qing-Dong Li Rong-Shu Shi jia-Rui Li Guang Yang hai-Bin Shi jian-Song Ji Yu-E Liu Zheng Cai Po Yang Yang Zhao xiao-Li Zhu Li-Gong Lu Gao-Jun Teng Center of Interventional Radiology&Vascular Surgery Department of RadiologyZhongda HospitalMedical SchoolSoutheast UniversityNanjing 210009China department of Minimally invasive Intervention The Affiliated Cancer Hospital of Zhengzhou UniversityZhengzhou 450008China department of Interventional Radiology the Third Affiliated HospitalSun Yat-Sen UniversityGuangzhou 510630China department of Interventional Radiology Union Hospital of Fujian Medical UniversityFuzhou 350001China department of Interventional Radiology Jiangsu Cancer Hospital&Jiangsu Institute of Cancer Research&The Affiliated Cancer Hospital of Nanjing Medical UniversityNanjing 210009China department of Interventional Radiology The First Affiliated Hospital of Soochow UniversitySoochow UniversitySuzhou 215006China Hepatobiliary and Pancreatic Interventional Treatment Center Division of Hepatobiliary and Pancreatic SurgeryThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China department of Interventional Radiology Eastern Hospital of Hepatobiliary SurgeryNavy Medical University(Second Military Medical University)Shanghai 200438China department of Interventional Radiology Nantong First People’s HospitalNantong 226001China department of Interventional Radiology Yancheng Third People’s HospitalYancheng 224008China department of Minimally Invasive Interventional Therapy Sun YatSen University Cancer CenterGuangzhou 510060China department of Vascular Surgery Southwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China. department of Interventional Radiology Hunan Cancer HospitalChangsha 410031China department of Interventional Oncology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510080China department of Interventional Radiology The Hospital of Nantong UniversityNantong 226001China department of Interventional Therapy Shanxi Tumor HospitalTaiyuan 030001China department of Interventional Radiology Tibet Autonomous Region People’s

There is considerable potential for integrating transarterial chemoembolization(TACE),programmed death-(ligand)1(PD-[L]1)inhibitors,and molecular targeted treatments(MTT)in hepatocellular carcinoma(HCC).It is necessary to investigate the therapeutic efficacy and safety of TACE combined with PD-(L)1 inhibitors and MTT in real-world *** this nationwide,retrospective,cohort study,826 HCC patients receiving either TACE plus PD-(L)1 blockades and MTT(combination group,n=376)or TACE monotherapy(monotherapy group,n=450)were included from January 2018 to May *** primary endpoint was progression-free survival(PFS)according to modified *** secondary outcomes included overall survival(OS),objective response rate(ORR),and *** performed propensity score matching approaches to reduce bias between two *** matching,228 pairs were included with a predominantly advanced disease *** PFS in combination group was 9.5 months(95%confidence interval[CI],8.4-11.0)versus 8.0 months(95%CI,6.6-9.5)(adjusted hazard ratio[HR],0.70,P=0.002).OS and ORR were also significantly higher in combination group(median OS,19.2[16.1-27.3]vs.15.7 months[13.0-20.2];adjusted HR,0.63,P=0.001;ORR,60.1%vs.32.0%;Pnation and monotherapy groups,*** results suggest that TACE plus PD-(L)1 blockades and MTT could significantly improve PFS,OS,and ORR versus TACE monotherapy for Chinese patients with predominantly advanced HCC in real-world practice,with an acceptable safety profile.

关键词： hepatocellular targeted matching

卡培他滨片剂在恶性肿瘤患者中的生物等效性研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国临床药理学杂志 2020年第22期36卷 3595-3599页

作者：刘青李劲彤李利亚王清张清媛孙涛宋振川王明霞王居峰刘中国贾军梅贾立群中日友好医院中西医结合肿瘤内科北京100029 中日友好医院药物临床试验研究中心黑龙江哈尔滨150081 哈尔滨医科大学附属肿瘤医院内科辽宁沈阳110042 辽宁省肿瘤医院内科河北石家庄050035 河北医科大学第四医院乳腺中心河北石家庄050035 河北医科大学第四医院临床药理研究部河南郑州450008 河南省肿瘤医院郑州大学附属肿瘤医院内科山西太原030001 山西医科大学第一医院Ⅰ期临床研究室山西太原030001 山西医科大学第一医院肿瘤科山西太原030001

目的评价国产卡培他滨片与原研卡培他滨片在恶性肿瘤患者体内的生物等效性。方法采用多中心、随机、开放、两周期、双交叉的餐后试验设计,84例可适用含卡培他滨片化疗方案的实体瘤患者随机分别口服国产与原研卡培他滨片剂,每周期服药1次... 详细信息

目的评价国产卡培他滨片与原研卡培他滨片在恶性肿瘤患者体内的生物等效性。方法采用多中心、随机、开放、两周期、双交叉的餐后试验设计,84例可适用含卡培他滨片化疗方案的实体瘤患者随机分别口服国产与原研卡培他滨片剂,每周期服药1次,单次给药1250 mg·m^-2,按照体表面积计算向下调整至0.5 g的整倍数片剂,给药两周期间清洗期为12 h。用液相色谱-质谱(LC-MS/MS)法测定血浆中卡培他滨浓度,进行生物等效性研究。结果实体瘤患者餐后服用卡培他滨片受试制剂和参比制剂后的药代动力学参数如下:Cmax分别为(3940±2300),(4040±2900)ng·mL^-1;AUC0-t分别为(4820±1620),(4750±1700)h·ng·mL^-1;AUC0-∞分别为(4870±1680),(4970±1750)h·ng·mL^-1。2种药物的Cmax、AUC0-t、AUC0-∞的几何均数比相对应的90%置信区间均在80.00%~125.00%。结论恶性肿瘤患者餐后口服卡培他滨片受试制剂和参比制剂具有生物等效性,且受试制剂和参比制剂不良事件发生情况相似。

关键词：卡培他滨片剂恶性肿瘤患者生物等效性药代动力学

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

血速升颗粒治疗贫血模型鼠的实验研究

河北医科大学学报 2018年第7期39卷 822-827页

作者：刘明峰杨金霞刘笑祁金龙贾庆忠河北医科大学第四医院药学部河北石家庄050011 河北医科大学基础医学院药理学教研室河北石家庄050017

目的评价血速升颗粒对于不同贫血模型的作用。方法分别建立小鼠急性失血性贫血模型及大鼠化疗药物引发的贫血模型。不同疾病模型均设置空白对照组、模型对照组、试验组及阳性药物对照组。造模前给药一段时间,造模开始后不同时间点取血,... 详细信息

目的评价血速升颗粒对于不同贫血模型的作用。方法分别建立小鼠急性失血性贫血模型及大鼠化疗药物引发的贫血模型。不同疾病模型均设置空白对照组、模型对照组、试验组及阳性药物对照组。造模前给药一段时间,造模开始后不同时间点取血,测定全血中白细胞、红细胞、血红蛋白、血小板及网织红细胞共5个指标。比较相同时间点,不同组别间各血液指标的统计学差异。结果血速升颗粒组在小鼠急性失血性贫血模型中,与模型对照组比较,红细胞、网织红细胞计数及血红蛋白含量升高,差异有统计学意义(P0.05);大鼠化疗性贫血模型中,与模型对照组比较,在化疗药物伤害期及恢复期白细胞、网织红细胞、红细胞计数及血红蛋白含量升高,差异有统计学意义(P0.05)。结论血速升颗粒能够改善小鼠急性失血导致的红细胞和血红蛋白减少,对化疗药物引起的白细胞、红细胞和血红蛋白降低有效,能够明显改善骨髓的造血功能。

关键词：贫血血速升颗粒小鼠大鼠

Fungal diversity notes 253-366:taxonomic and phylogenetic contributions to fungal taxa

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fungal Diversity 2016年第3期78卷 1-237页

作者： Guo Jie Li Kevin D.Hyde Rui lin Zhao Sinang Hongsanan Faten Awad Abdel-Aziz Mohamed A.Abdel-Wahab Pablo Alvarado Genivaldo Alves-Silva Joseph F.Ammirati Hiran A.Ariyawansa Abhishek Baghela Ali Hassan Bahkali Michael Beug D.Jayarama Bhat Dimitar Bojantchev Thitiya Boonpratuang Timur S.Bulgakov Erio Camporesi Marcela CBoro Oldriska Ceska Dyutiparna Chakraborty jia jia Chen K.W.Thilini Chethana Putarak Chomnunti Giovanni Consiglio Bao Kai Cui Dong Qin Dai Yu Cheng Dai Dinushani A.Daranagama Kanad Das Monika C.Dayarathne Eske De Crop Rafael J.V.De Oliveira Carlos Alberto Fragoso de Souza JoséIde Souza Bryn T.M.Dentinger Asha J.Dissanayake Mingkwan Doilom E.Ricardo Drechsler-Santos Masoomeh Ghobad-Nejhad Sean P.Gilmore Aristóteles Góes-Neto MichałGorczak Charles H.haitjema Kalani Kanchana Hapuarachchi Akira Hashimoto Mao Qiang He John K.Henske Kazuyuki Hirayama Maria J.Iribarren Subashini C.Jayasiri Ruvishika S.Jayawardena Sun Jeong Jeon Gustavo H.Jerônimo Ana L.Jesus E.B.Gareth Jones Ji chuan Kang Samantha C.Karunarathna Paul M.Kirk Sirinapa Konta Eric Kuhnert Ewald Langer Haeng Sub Lee Hyang Burm Lee Wen Jing Li Xing Hong Li Kare Liimatainen Diogo Xavier Lima chuan Gen lin jian Kui Liu Xings zhong Liu Zuo Yi Liu J.Jennifer Luangsa-ard Robert Lücking H.Thorsten Lumbsch Saisamorn Lumyong Eduardo M.Leaño Agostina V.Marano Misato Matsumura Eric H.C.McKenzie Suchada Mongkolsamrit Peter E.Mortimer Thi Thuong Thuong Nguyen Tuula Niskanen Chada Norphanphoun Michelle A.O’Malley Sittiporn Parnmen Julia Pawłowska Rekhani H.Perera Rungtiwa Phookamsak Chayanard Phukhamsakda Carmen L.A.Pires-Zottarelli Olivier Raspé Mateus A.Reck Sarah C.O.Rocha AndréL.C.M.Ade Santiago Indunil C.Senanayake Ledo Setti Qiu Ju Shang Sanjay K.Singh Esteban B.Sir Kevin V.Solomon Jie Song Prasert Srikitikulchai Marc Stadler Satinee Suetrong Hayato Takahashi Takumasa Takahashi Kazuaki Tanaka Li Ping Tang Kasun M.Thambugala Donnaya Thanakitpipattana Michael K.Theodorou Benjarong Thongbai Tuksaporn Thummarukcharoen qing Tian Saowaluck Tibpromma Annemieke State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesNo 31st West Beichen RoadChaoyang DistrictBeijing 100101People’s Republic of China Centre of Excellence in Fungal Research and School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box:2455Riyadh 1145Saudi Arabia department of Botany and Microbiology Faculty of ScienceSohag UniversitySohag 82524Egypt ALVALAB C/La Rochela nº47E-39012 SantanderSpain Micolab Programa de Pós-Graduação em Biologia de FungosAlgas e PlantasDepartamento de BotânicaUniversidade Federal de Santa CatarinaCampus Universitário TrindadeCEP:88040-900 FlorianópolisSanta CatarinaBrazil department of Biology University of WashingtonBox 351800SeattleWA 98195-1800USA Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouPeople’s Republic of China national Fungal Culture Collection of India(NFCCI) Biodiversity and Palaeobiology GroupMACS’Agharkar Research InstituteG.G.Agarkar RoadPune 411004India PO Box 116 HusumWA 98623-0116USA Formerly Department of BotanyGoa UniversityGoaIndia No.128/1-J Azad Housing SocietyCurcaP.O.Goa Velha 403108India *** 345 Shipwatch LaneHerculesCA 94547USA Microbe Interaction Laboratory(BMIT) BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoeKhlong LuangPathum Thani 12120Thailand Academy of Biology and Biotechnology Southern Federal UniversityRostov-on-Don 344090Rostov regionRussia A.M.B.Gruppo Micologico Forlivese BAntonio“Cicognani” Via Roma Forlì Italy 18 A.M.B.Circolo Micologico“Giovanni Carini”C.P.314BresciaItaly Societàper gli Studi naturalistici della Romagna C.P.144Bagnacavallo

Notes on 113 fungal taxa are compiled in this paper,including 11 new genera,89 new species,one new subspecies,three new combinations and seven reference *** geographic and taxonomic range of fungal taxa are *** the Ascomycota the new genera Angustospora(Testudinaceae),Camporesia(Xylariaceae),Clematidis,Crassiparies(Pleosporales genera incertae sedis),Farasanispora,Longiostiolum(Pleosporales genera incertae sedis),Multilocularia(Parabambusicolaceae),Neophaeocryptopus(Dothideaceae),Parameliola(Pleosporales genera incertae sedis),and Towyspora(Lentitheciaceae)are *** introduced species are Angustospora nilensis,Aniptodera aquibella,Annulohypoxylon albidiscum,Astrocystis thailandica,Camporesia sambuci,Clematidis italica,Colletotrichum menispermi,***,Comoclathris pimpinellae,Crassiparies quadrisporus,Cytospora salicicola,Diatrype thailandica,Dothiorella rhamni,durotheca macrostroma,Farasanispora avicenniae,Halorosellinia rhizophorae,Humicola koreana,Hypoxylon lilloi,Kirschsteiniothelia tectonae,lindgomyces okinawaensis,Longiostiolum tectonae,Lophiostoma pseudoarmatisporum,Moelleriella phukhiaoensis,***,Mucoharknessia anthoxanthi,Multilocularia bambusae,Multiseptospora thysanolaenae,Neophaeocryptopus cytisi,Ocellularia arachchigei,***,Ochronectria thailandica,Ophiocordyceps karstii,Parameliola acaciae,***,Parastagonospora cumpignensis,Pseudodidymosphaeria phlei,Polyplosphaeria thailandica,Pseudolachnella brevifusiformis,Psiloglonium macrosporum,Rhabdodiscus albodenticulatus,Rosellinia chiangmaiensis,Saccothecium rubi,Seimatosporium pseudocornii,***,Sigarispora ononidis and Towyspora *** combinations are provided for Eutiarosporella dactylidis(sexual morph described and illus trated)and Pseudocamarosporium ***,illustrations and/or reference specimens are designated for Aposphaeria corallinolutea,Cryptovalsa ampelina,Dothiorella vidmadera,Ophiocordyceps formosana,P

关键词： Ascomycota Basidiomycota Neocallimastigomycota Oomycota.Zygomycota Phylogeny Taxonomy New genus New species