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Simulation and test on the operation process of an intermittent filmpicking component on full-film mulched double ditches

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International Journal of Agricultural and Biological Engineering 2024年第1期17卷 99-108页

作者： fei Dai Feng Wang Wenjuan guo Ruijie Shi Shanglong Xin Xiaolong Liu Wuyun Zhao College of Mechanical and Electrical Engineering Gansu Agricultural UniversityLanzhou 730070China School of Cyber Security Gansu University of Political Science and LawLanzhou 730070China

In view of the problems in operation process of fixed rake-type residual recycling component,such as poor individual profiling effect in film picking,easy clogging of the compound of films,soil and corn stubbles,high power consumption in film picking,and strong disturbance to seedbed soil,in this study,an operation model of intermittent filmpicking on full-film mulched double ditches was proposed and an intermittent film picking component was *** DEMMBD coupled algorithm was adopted for numerical simulation on the operation process of the intermittent film-picking component on full-film mulched double ditches,and a comparative analysis was carried out on the seedbed disturbance effect and resistance variation characteristics in film-picking by fixed and intermittent film-picking *** taking the forward speed in film-picking,cam arrangement angle of the film-picking component and rotating speed of the cam shaft as independent variables,film-picking rate as the response value,a mathematical model between test factors and the film-picking rate was established,to explore the influence order of the factors on film-picking rate,and the optimal working parameters of the intermittent film-picking component were obtained as follows:the forward speed in film-picking was 2 km/h,cam arrangement angle was 180°,rotating speed of the cam shaft was 120 r/*** the optimal parameter combination,the average film-picking rate of the simulation test was 96.1%.Field test showed that,the average film-picking rate of the intermittent film-picking component was 95.6%,and 0.5%higher than that of the simulation *** working condition of the sample machine was basically consistent with the simulation process,and can accurately represent the operation mechanism of intermittent film-picking on full-film mulched double ditches,showing that the established discrete element simulation model and its parameters were accurate and reasonable.

关键词： full-film mulched double ditches residual film recovery intermittent film-picking component DEM-MBD parameter optimization

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OSW-1 triggers necroptosis in colorectal cancer cells through the RIPK1/RIPK3/MLKL signaling pathway facilitated by the RIPK1- p62/SQSTM1 complex

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World Journal of Gastroenterology 2024年第15期30卷 2155-2174页

作者： Nan Wang Chao-Yang Li Teng-fei Yao Xiao-Dan Kang Hui-Shu guo Clinical Laboratory Medicine The First Affiliated Hospital of Dalian Medical UniversityDalian 116023Liaoning ProvinceChina The Institute of Integrative Medicine Dalian Medical UniversityDalian 116044Liaoning ProvinceChina The Institute of Laboratory Medicine Dalian Medical UniversityDalian 116044Liaoning ProvinceChina Central Laboratory The First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina

BACKGROUND Necroptosis has emerged as a novel molecular pathway that can be targeted by chemotherapy agents in the treatment of ***-1,which is derived from the bulbs of Ornithogalum saundersiae Baker,exerts a wide range of pharmaco-logical *** To explore whether OSW-1 can induce necroptosis in colorectal cancer(CRC)cells,thereby expanding its range of clinical *** We performed a sequence of functional experiments,including Cell Counting Kit-8 assays and flow cytometry analysis,to assess the inhibitory effect of OSW-1 on CRC *** utilized quantitative proteomics,employing tandem mass tag label-ing combined with liquid chromatography-tandem mass spectrometry,to analyze changes in protein *** bioinformatic analysis was conducted to elucidate the biological processes associated with the identified *** electron microscopy(TEM)and immunofluorescence studies were also performed to examine the effects of OSW-1 on ***,western blotting,siRNA experiments,and immunoprecipitation were employed to evaluate protein interactions within CRC *** The results revealed that OSW-1 exerted a strong inhibitory effect on CRC cells,and this effect was accompanied by a necroptosis-like morphology that was observable via ***-1 was shown to trigger necroptosis via activation of the RIPK1/RIPK3/MLKL ***,the accumulation of p62/SQSTM1 was shown to mediate OSW-1-induced necroptosis through its interaction with *** We propose that OSW-1 can induce necroptosis through the RIPK1/RIPK3/MLKL signaling pathway,and that this effect is mediated by the RIPK1-p62/SQSTM1 complex,in CRC *** results provide a theoretical foundation for the use of OSW-1 in the clinical treatment of CRC.

关键词： OSW-1 Necroptosis RIPK1 P62/SQSTM1 Colorectal cancer

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Influence of Electroshocking Treatment on Microstructure and Mechanical Properties of Ti-6.5Al-3.5Mo-1.5Zr-0.3Si Thin-Wall Specimen Manufactured by Laser Melting Deposition

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Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 145-158页

作者： Yan Wen Xuan Sun Jian Zhou Bingliang Liu Haojie guo Yuxin Li fei Yin Liqiang Wang Lechun Xie Lin Hua Hubei Key Laboratory of Advanced Technology for Automotive Components Wuhan University of TechnologyWuhan430070China Hubei Collaborative Innovation Center for Automotive Components Technology Wuhan430070China Hubei Longzhong Laboratory Xiangyang441000China Shanghai Aircraft Manufacturing Co. Ltd.Commercial Aircraft Corporation of ChinaLtd.Shanghai201324China State Key Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai200240China

In order to improve the properties of titanium alloys manufactured by laser melting deposition(LMD),the electroshocking treatment(EST)was proposed in this *** effects of EST on microstructure and mechanical properties of LMD Ti-6.5Al-3.5Mo-1.5Zr-0.3Si were *** results showed that the width of the heat affected band decreased and disappeared under the thermal and athermal effects of EST,resulting in the uniform *** the microstructure,theαlaths became coarser gradually,and the quantity ofα/βinterface was *** reduction of the quantity ofα/βinterface leads to make less resistant to dislocation,resulting in the reduction in hardness and *** discontinuous grain boundaryαphase and nucleationαcolony near grain boundary inhibited the crack propagation and improved the ***,EST can manipulate the microstructure and improve the mechanical properties of LMD titanium alloys.

关键词： Electroshocking treatment(EST) Laser melting deposition(LMD) Titanium alloy Microstructure Mechanical properties

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Geometric-like imaginarity:Quantification and state conversion

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Science China(Physics,Mechanics & Astronomy) 2024年

作者： Meng-Li guo Bo Li Shao-Ming fei School of Science East China University of Technology School of Computer and Computing Science Hangzhou City University School of Mathematical Sciences Capital Normal University

From the perspective of resource-theoretic approach, this study explores the quantification of imaginary in quantum physics. We propose a well defined measure of imaginarity, the geometric-like measure of imaginarity. Compared with the usual geometric imaginarity measure, this geometric-like measure of imaginarity exhibits smaller decay difference under quantum noisy channels and higher stability. As applications, we show that both the optimal probability of state transformations from a pure state to an arbitrary mixed state via real operations, and the maximal probability of stochastic-approximate state transformations from a pure state to an arbitrary mixed state via real operations with a given fidelity f, are given by the geometric-like measure of imaginarity.

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Frequency and size change of ice–snow avalanches in the central Himalaya:A case from the Annapurna Ⅱ glacier

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Advances in Climate Change Research 2024年第3期15卷 464-475页

作者： Yao LI Yi-fei CUI Jian-Sheng HAO Zheng-Tao ZHANG Hao WANG Jian guo Shuo-Fan WANG State Key Laboratory of Hydroscience and Engineering Department of Hydraulic EngineeringTsinghua UniversityBeijing 100084China Key Laboratory of Hydrosphere Sciences of the Ministry of Water Resources Beijing 100084China Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China School of National Safety and Emergency Management Beijing Normal UniversityBeijing 100875China Key Laboratory of Mountain Hazards and Earth Surface Process Institute of Mountain Hazards and EnvironmentChinese Academy of SciencesChengdu 610041China

Glaciers have retreated and shrunk in High Mountain Asia since the mid-20th century because of global warming,leading to glacier instability and hazardous iceesnow ***,the complex relationship between iceesnow avalanches and factors such as climate and potential triggers are difficult to understand because of the lack of observational ***,we addressed iceesnow avalanches on the Annapurna Ⅱ glacier in Nepal,Central *** constructed an iceesnow avalanche history using long-term multi-source remote sensing images(1988-2021)and mapped the velocity fields of glaciers using cross-correlation analysis on SAR and optical ***,we investigated the impact of climate change and earthquakes on the frequency and size of iceesnow *** results demonstrate that the frequency of iceesnow avalanches has increased from 10 in 1988 to 27 in 2020,but the average area of iceesnow avalanche deposits has decreased by approximately 70%,from 3.4×10^(5) m^(2) in 1988 to 1.2×10^(5) m^(2) in *** evolutionary characteristic of ice avalanches is linked to the impact of glacier retreat(reduction in ice material supply)and increased activity under climate *** glacier movement velocity controls the size of iceesnow avalanches and can be set as an indicator for iceesnow avalanche *** the Annapurna Ⅱ glacier,an iceesnow avalanche occurred when the glacier velocities were greater than 1.5 m d^(-1).These results offer insights into iceesnow avalanche risk assessment and prediction in high-mountain areas,particularly in regions characterised by dense glacier distribution.

关键词： Iceesnow avalanche Glacier instability Climate change Central Himalaya Remote sensing

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Physical and mechanical properties and microstructures of submarine soils in the Yellow Sea

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Deep Underground Science and Engineering 2024年第2期3卷 197-206页

作者： Zhuangcai Tian Yihua Chang Sichao Chen Gengchen Wang Yanhong Hu chuan guo Lei Jia Lei Song Jianhua Yue State Key Laboratory for Geomechanics and Deep Underground Engineering China University of Mining and TechnologyXuzhouChina School of Mechanics and Civil Engineering China University of Mining and TechnologyXuzhouChina Research Center for Deep Ocean Science and Underwater Engineering China University of Mining and TechnologyXuzhouChina School of Resources and Geosciences China University of Mining and TechnologyXuzhouChina

In recent years,the exploration of seabed has been intensified,but the submarine soils of silt and sand in the Yellow Sea area have not been well investigated so *** this study,the physical and mechanical properties of silt and sand from the Yellow Sea were measured using a direct shear apparatus and their microstructures were observed using a scanning electron *** test results suggest that the shear strength of silt and sand increases linearly with the increase of normal *** on the direct shear test,the scanning electron microscope was used to observe the section surface of *** is observed that the section surface becomes rough,with many“V”‐shaped *** particles appear on the surface of the silt structure and tend to be *** X‐ray diffraction experiment reveals that the sand and silt have different *** shear strength of sand is slightly greater than that of silt under high stress,which is related to the shape of soil particles and the mineral *** results can be a reference for further study of other soils in the Yellow Sea;meanwhile,they can serve as soil parameters for the stability and durability analyses of offshore infrastructure construction.

关键词： direct shear test microscope physical properties submarine soil Yellow Sea

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In situ synthesis of porous Pt-Pd bimetallic structures for sweat glucose biosensing using dynamic hydrogen bubble template method

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Rare Metals 2024年第7期43卷 3408-3414页

作者： Yi-Wen guo Qian-Hui Wei fei Wei Hao Liu Hong-Bin Zhao Dong Wang Hai-Ling Tu State Key Laboratory of Advanced Materials for Smart Sensing China GRINM Group Co.Ltd.Beijing 100088China Department of Advanced Electronic Materials GRIMAT Engineering Institute Co.Ltd.Beijing 101407China General Research Institute for Nonferrous Metals Beijing 100088China GRINM(Guangdong)Institute for Advanced Materials and Technology Foshan 528000China School of Chemical Engineering Northeast Electric Power UniversityJilin 132012China

For the practical application of sweat glucose biosensors,it is crucial to develop a method for modifying the working electrode with noble metals that ensures strong *** this study,we synthesized porous Pt-Pd bimetall... 详细信息

关键词： method bubble porous

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Overview on Mangrove Forest Disaster Prevention and Mitigation Functions

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Journal of Ocean University of China 2024年第1期23卷 46-56页

作者： CHEN Xinping YIN Ziqi LI Zibin WANG Bin TAO Aifeng guo Zhixing WANG fei AN Yanhong O’DRISCOLL Kieran College of Harbour Coastal and Offshore EngineeringHohai UniversityNanjing 210098China National Marine Hazard Mitigation Service Beijing 100194China The People’s Government of Hainan Province Haikou 570204China Hibernian Marine Systems Limited Cork T12EDD8Ireland

This paper provides a comprehensive overview on coastal protection and hazard mitigation by *** stud-ies have made great strides to understand the mechanisms and influencing factors of mangroves’protection function,including wave energy dissipation,storm surge damping,tsunami mitigation,adjustment to sea level rise and wind speed reduction,which are sys-tematically summarized in this ***,the study analyzes the extensive physical models,based on indoor flume experi-ments and numerical models,that consider the interaction between mangroves and hydrodynamics,to help our understanding of mangrove-hydrodynamic ***,quantitative approaches for valuing coastal protection services provided by man-groves,including index-based and process-resolving approaches,are introduced in ***,we point out the limitations of previous studies,indicating that efforts are still required for obtaining more long-term field observations during extreme weather events,to create more real mangrove models for physical experiments,and to develop numerical models that consider the flexible properties of mangroves to better predict wave propagation in mangroves having complex morphology and structures.

关键词： mangrove coastal protection disaster prevention and mitigation disaster reduction value coastal resilience

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Natural rubber latex as a potential additive for water-based drilling fluids

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Petroleum Science 2024年第4期21卷 2677-2687页

作者： Jun Yang Guan-Cheng Jiang Jing-Tian Yi Yin-Bo He Li-Li Yang Teng-fei Dong guo-Shuai Wang College of Petroleum Engineering China University of Petroleum (Beijing) National Engineering Research Center of Oil & Gas Drilling and Completion Technology Changqing Drilling General Company CNPC Chuanqing Drilling Engineering Company Limited

The environmental hazards and "carbon footprint" of oil and gas drilling can be significantly reduced by replacing traditional petroleum-based chemical additives with natural materials derived from plants and animals. This paper explored for the first time the interaction mechanism between natural rubber latex(NRL) and bentonite suspensions(BTs) through a series of characterization experiments, as well as the potential applications in water-based drilling fluids(WBDF). The gel viscoelasticity experiments showed that NRL could decrease the consistency coefficient(k) and flow index(n) of BTs, and enhance the shear thinning performance of BTs as pseudo-plastic fluids. In addition, 0.5 w/v% NRL not only increased the critical yield stress and strengthened the structural strength between the bentonite particles, but also facilitated the compatibility of pressure loss and flow efficiency. The evaluation of colloidal stability and WBDF performance indicated that NRL particles could promote the hydration and charge stability on the surface of BTs particles, and optimize the particle size distribution and flow resistance of WBDF under the "intercalation-exfoliation-encapsulation" synergistic interaction. Moreover, NRL can improve the rheological properties of WBDF at high temperatures(<150.C), and form a dense blocking layer by bridging and sealing the pores and cracks of the filter cake, which ultimately reduces the permeability of the cake and the filtration loss of WBDF.

关键词： Natural materials Water-based drilling fluids Natural rubber latex Bentonite suspensions Filtration loss

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Th17/Treg balance and macrophage polarization ratio in lower extremity arteriosclerosis obliterans

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Asian Pacific Journal of Tropical Biomedicine 2024年第3期14卷 127-136,I0006-I0009页

作者： Zhen-Zhen Li Min Liu Xiong-Hui He Zhen-Dong Liu Zhan-Xiang Xiao Hao Qian You-fei Qi Cun-chuan Wang Department of Metabolic and Bariatric Surgery The First Affiliated Hospital of Jinan UniversityGuangzhouGuangdong Province510632China Department of Vascular Surgery Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikouHainan Province570311China Department of Physical Examination Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikouHainan Province570311China Department of Gastrointestinal Surgery Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikouHainan Province570311China

Objective:To explore the balance of peripheral blood T helper 17 cells/regulatory T cell(Th17/Treg)ratio and the polarization ratio of M1 and M2 macrophages in lower extremity arteriosclerosis obliterans(ASO).Methods:A rat model of lower extremity ASO was established,and blood samples from patients with lower extremity ASO before and after surgery were *** was used to detect interleukin 6(IL-6),IL-10,and ***-time RCR and Western blot analyses were used to detect Foxp3,IL-6,IL-10,and IL-17 ***,flow cytometry was applied to detect the Th17/Treg ratio and M1/M2 ***:Compared with the control group,the iliac artery wall of ASO rats showed significant hyperplasia,and the concentrations of cholesterol and triglyceride were significantly increased(P<0.01),indicating the successful establishment of ***,the levels of IL-6 and IL-17 in ASO rats were pronouncedly increased(P<0.05),while the IL-10 level was significantly decreased(P<0.05).In addition to increased IL-6 and IL-17 levels,the mRNA and protein levels of Foxp3 and IL-10 in ASO rats were significantly decreased compared with the control *** Th17/Treg and M1/M2 ratios in the ASO group were markedly increased(P<0.05).These alternations were also observed in ASO *** endovascular surgery(such as percutaneous transluminal angioplasty and arterial stenting),all these changes were significantly improved(P<0.05).Conclusions:The Th17/Treg and M1/M2 ratios were significantly increased in ASO,and surgery can effectively improve the balance of Th17/Treg,and reduce the ratio of M1/M2,and the expression of inflammatory factors.

关键词： Lower extremity arteriosclerosis Regulatory T cells Regulatory B cells Inflammatory factors M1 macrophages M2 macrophages

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