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Pushing the Limit of Flexible Batteries

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CCS Chemistry 2023年第3期5卷 531-543页

作者： chuan xie Yanpeng Guo Zijian Zheng Department of Applied Biology and Chemical Technology Faculty of ScienceThe Hong Kong Polytechnic UniversityHung HomHong Kong School of Fashion and Textiles The Hong Kong Polytechnic UniversityHung HomHong Kong Research Institute for Intelligent Wearable Systems(RI-IWEAR) The Hong Kong Polytechnic UniversityHung HomHong Kong Research Institute for Smart Energy(RISE) The Hong Kong Polytechnic UniversityHung HomHong Kong

Alongside the rapid development of flexible and wearable electronics,the search for reliable,safe,and high-energy rechargeable flexible batteries(FBs)has become a research hotspot in recent *** there are some prototype FBs exhibited by the industry and a rapidly increasing number of publications reported by academia,most demonstrations are shown on a laboratory scale,and it is still difficult to find real implementation of the technology in the *** perspective aims to discuss and analyze the key metrics,including energy density,flexibility,and safety,that are critical to pushing FBs to a commercially viable level,with a special focus on the lithium batteries and zinc batteries most reported in the *** first compare the figure of merit of FBs(fbFOM)of existing lithium-based and zinc-based FBs with the requirement for market *** then analyze the most desired cell configurations toward high flexibility,followed by systematic discussions on features and materials selection toward high energy density ***,we discuss strategies to enhance battery *** outlook of the future developments needed to address the gaps between the state-of-the-art demonstrations and real applications is provided at the end of this article.

关键词： flexible battery energy density safety lithium battery zinc battery

Magnetic resonance imaging features of intrahepatic extramedullary hematopoiesis: Three case reports

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World Journal of Clinical Cases 2022年第19期10卷 6626-6635页

作者： Ma Luo Jia-Wen Chen chuan-Miao xie Department of Radiology Sun Yat-sen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina State Key Laboratory of Oncology in South China Guangzhou 510060Guangdong ProvinceChina Collaborative Innovation Center for Cancer Medicine Guangzhou 510060Guangdong ProvinceChina

BACKGROUND Extramedullary hematopoiesis rarely occurs within the liver alone,and is easily *** radiological literature on this disease is exclusively case *** is a paucity of literature on the role of magnetic resonance imaging(MRI).The most common imaging modalities used are computed tomography and *** report aims to provide more data on the appearance of extramedullary hematopoiesis using MRI to help radiologists establish the *** SUMMARY Three patients(one male and two females)were incidentally found to have a hepatic mass or nodule,without hepatomegaly or *** tests including liver function,serum hepatic tumor markers,and hepatitis serologic markers were *** MRI scans,all lesions showed lower signal intensity on in-phase images than on out-phase *** case showed changes in signal intensity on T2 weighted images(WI)and diffusion WI,which shifted from hyperintensity to hypointensity with size enlargement between two rounds of imaging *** lesions exhibited different enhancement patterns on dynamic contrast enhancement *** The MRI signal change and in-/out-phase image might provide useful information and help radiologists establish the diagnosis of intrahepatic extramedullary hematopoiesis.

关键词： Liver Extramedullary hematopoiesis Signal intensity Magnetic resonance imaging Case report

Potential of traditional Chinese medicine in the treatment of nonalcoholic fatty liver disease:A promising future

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World Journal of Gastroenterology 2024年第43期30卷 4597-4601页

作者： Wen-Yige Zhang Meng-Hui Wang chuan xie Department of Gastroenterology Jiangxi Provincial Key Laboratory of Digestive DiseasesJiangxi Clinical Research Center for GastroenterologyDigestive Disease HospitalThe First Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Queen Mary College of Nanchang University Jiangxi Medical CollegeNanchang 330006Jiangxi ProvinceChina

In this editorial,we provide insights into the publication by Niu et al featured in the latest edition of the World Journal of ***,our focus was on exploring the potential of traditional Chinese medicine(TCM)in treating nonalcoholic fatty liver disease(NAFLD)induced by a high-fat diet through various *** is a common liver condition,affecting approximately 25%of the world's *** is closely linked to metabolic syndrome,insulin resistance,excessive body weight,and irregular lipid processing,leading to fat accumulation in the liver,as well as oxidative stress and *** maintaining a healthy diet and active lifestyle are essential for managing NAFLD,treatment options are limited due to undefined pathogenesis and a lack of specific ***,rooted in traditional Chinese practices,presents a promising alternative through its"syndrome differentiation and treatment"principles,enhancing liver lipid metabolism,reducing inflammation,and addressing *** herbs,such as Poria cocos,Puaria lobata,and Salvia miltiorrhiza,have shown significant efficacy in reducing fat deposition and improving liver *** to systematic research and analysis of mechanisms,TCM is anticipated to yield new approaches to prevent and treat NAFLD,increasing its clinical application.

关键词： Nonalcoholic fatty liver disease Traditional Chinese medicine High-fat diet Potential Prospects

Primary mesonephric adenocarcinoma of the fallopian tube:A case report

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World Journal of Clinical Cases 2021年第18期9卷 4741-4747页

作者： chuan xie Yang-Mei Shen Qiu-He Chen Ce Bian Department of Gynecology and Obstetrics Key Laboratory of Birth Defects and Related Diseases of Women and ChildrenMinistry of EducationWest China Second University HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Pathology Key Laboratory of Birth Defects and Related Diseases of Women and ChildrenMinistry of EducationWest China Second University HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Mesonephric adenocarcinoma(MNAC)is an extremely rare malignancy in the female genital *** a few cases have been reported in the literature,and most of them occurred in the cervix,with extremely rare cases in the uterine body and *** has never been reported to arise in the fallopian *** SUMMARY A 45-year-old woman was referred to our institution with a history of abdominal *** revealed a cystic and solid mass in left adnexal *** patient underwent complete staging surgery when intraoperative pathological examination demonstrated that the mass was *** final histological and immunohistochemical results confirmed the diagnosis of MNAC originating from the fallopian *** she received four cycles of combination chemotherapy with carboplatin plus *** tumor recurred with hepatic metastases 4 mo after initial surgery,and second resection of the tumors in the liver plus partial hepatectomy was *** was supplemented with five courses of a new combination chemotherapy with gemcitabine plus carboplatin,and there was no evidence of recurrence within the 22-mo follow-up period after the second *** MNAC originating from the fallopian tube is an extremely rare and high malignancy with a poor *** can be very aggressive,even at early *** is known about the clinical characteristics,pathological diagnosis,prognosis,and optimal management strategy of MNAC originating from the fallopian *** we report the first case of primary MNAC deriving from the fallopian tube.

关键词： Mesonephric adenocarcinoma Mesonephric-like adenocarcinoma Fallopian tube Surgery Chemotherapy Case report

Modulation of host N6-methyladenosine modification by gut microbiota in colorectal cancer

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World Journal of Gastroenterology 2024年第38期30卷 4175-4193页

作者： Tian-Qi Jiang Hao Wang Wang-XinJun Cheng chuan xie Department of Gastroenterology Jiangxi Provincial Key Laboratory of Digestive DiseasesJiangxi Clinical Research Center for Department of GastroenterologyDigestive Disease HospitalThe First Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina The First Clinical Medical College Nanchang UniversityNanchang 330006Jiangxi ProvinceChina Queen Mary College Nanchang UniversityNanchang 330006Jiangxi ProvinceChina

As a research hotspot in the field of molecular biology,N6-methyladenosine(m6A)modification has made progress in the treatment of colorectal cancer(CRC),leukemia and other *** studies have demonstrated that the tumour microenvironment(TME)regulates the level of m6A modification in the host and activates a series of complex epigenetic signalling pathways through interactions with CRC cells,thus affecting the progression and prognosis of ***,with the diversity in the composition of TME factors,this action is reci-procal and ***,some studies have experimentally revealed that the intestinal flora can alter CRC cell proliferation by directly acting on m6A and thereby altering CRC cell *** review summarizes the data,supporting the idea that the intestinal flora can influence host m6A levels through pathways such as methyl donor metabolism and thus affect the progression of *** also review the role of m6A modification in the diagnosis,treatment,and prognostic assessment of CRC and discuss the current status,limitations,and potential clinical value of m6A modification in this *** propose that additional in-depth research on m6A alterations in CRC patients and their TME-related targeted therapeutic issues will lead to better therapeutic outcomes for CRC patients.

关键词： Colorectal cancer N6-methyladenosine Tumour microenvironment Gut microbiota Clinical application

Abnormal DNA-PKcs and Ku 70/80 expression may promote malignant pathological processes in gastric carcinoma

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World Journal of Gastroenterology 2013年第40期19卷 6894-6901页

作者： Wei Li chuan xie Zhen Yang Jiang Chen Nong-Hua Lu Department of Gastroenterology the First Affiliated Hospital of Nanchang University

AIM:To determine the expression of the catalytic subunit of DNA-dependent protein kinase(DNA-PKcs)and the Ku70/Ku80 heterodimer(Ku 70/80)in gastric ***:Gastric biopsies were obtained from 146gastric carcinoma patients[Helicobacter pylori(***)-negative:89 and ***-positive:57]and 34from normal subjects(***-negative:16 and ***-positive:18)via surgery and endoscopic detection from April 2011 to August 2012 at the First Affiliated Hospital of Nanchang *** diagnosis and classification were made according to the criteria of the World Health Organization and the updated Sydney ***‘‘in-house’’rapid urease test and modified Giemsa staining were employed to detect *** *** expression of DNA-PKcs and the Ku 70/80protein was detected by ***:Overall,the positive rates of both DNA-PKcs and Ku 70/80 were significantly increased in gastric cancer(χ2=133.04,P<0.001 for DNA-PKcs andχ2=13.06,P<0.01 for Ku)compared with normal gastric *** was hardly any detectable expression of DNA-PKcs in normal gastric mucosa,and the positive rate of DNA-PKcs protein expression in patients with a normal gastric mucosa was 0%(0/34),whereas the rate in gastric cancer(GC)was 93.8%(137/146).The difference between the two groups was statistically ***,the positive rate of Ku 70/80 was79.4%(27/34)in normal gastric mucosa and 96.6%(141/146)in gastric *** DNA-PKcs protein level was significantly increased in gastric cancer(MannWhitney U=39.00,P<0.001),compared with normal gastric *** addition,there was a significant difference in the expression of Ku 70/80(Mann-Whitney U=1117.00,P<0.001)between gastric cancer and normal gastric *** was also a significant difference in Ku70/80 protein expression between GC patients with and without *** infection(P<0.05).Spearman analysis showed a negative correlation between tumor differentiation and DNA-PKcs expression(r=-0

关键词： Helicobacter pylori Catalytic subunit of the DNA-dependent protein kinase Ku70/Ku80 heterodimer Gastric carcinoma Immunohistochemistry

Experimental study on gas slippage of Marine Shale in Southern China

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Petroleum 2016年第2期2卷 171-176页

作者： Ying Ren Xiao Guo chuan xie Hongqin Wu State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityNo.8Xindu AvenueXindu DistrictChengdu 610500China Shunan Division of Southwest Oil and Gasfield Company PetroChinaSichuanLuzhou 646000China Research Institute of Drilling Engineering Sinopec Southwest Petroleum Engineering CompanySichuanDeyang 618000China

The shale gas reservoirs are composed of porous media of different length scales such as nanopores,micropores,natural fractures and hydraulic fractures,which lead to high *** flow from pores to fractures is under different flow regimes and in the control of various flow *** gas slippage would have significant effects on gas flow in *** obtain the effect of slippage on gas flow in matrix and fractures,contrast experiments were run by using cores with penetration fractures and no fractures from Marine Shale in Southern China under constant confining *** results showed that slippage effect dominates and increases the gas permeability of cores without *** cores with penetration fractures,slippage effect is associated with the closure degree of *** dominates when fractures close under low pore *** weakens due to the fractures opening under high pore *** opening reduces the seepage resistance and slippage *** Forchheimer effect occurs and leads to a permeability reduction.

关键词： Shale gas Permeability Fracture Slippage Effective stress

A simple way to visualize detailed phylogenetic tree of huge genome-wide SNP data constructed by SNPhylo

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Journal of Integrative Agriculture 2018年第9期17卷 1972-1978页

作者： YANG Hai-long DONG Le WANG Hui LIU Chang-lin LIU Fang xie chuan-xiao National Key Facility for Crop Gene Resources and Genetic Improvement/Institute of Crop Sciences Chinese Academy of Agricultural Sciences

Phylogenetic trees based on genome-wide single nucleotide polymorphisms （SNPs） among diverse inbreds could provide valuable and intuitive information for breeding and germplasm management in crops. As a result of sequencing technology developments, a huge amount of whole genome SNP data have become available and affordable for breeders. However, it is a challenge to perform quick and reliable plotting based on the huge amount of SNP data. To meet this goal, a visualization pipeline was developed and demonstrated based on publicly available SNP data from the current important maize inbred lines, including temperate, tropical, sweetcorn, and popcorn. The detailed phylogenetic tree plotted by our pipeline revealed the authentic genetic diversity of these inbreds, which was consistent with several previous reports and indicated that this straightforward pipeline is reliable and could potentially speed up advances in crop breeding.

关键词： phylogenetic tree SNP genetic diversity

Potential effect of chronic Helicobacter pylori infection on glucose metabolism of Mongolian gerbils

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World Journal of Gastroenterology 2015年第44期21卷 12593-12604页

作者： Zhen Yang Wei Li Cong He chuan xie Yin Zhu Nong-Hua Lu Department of Gastroenterology The First Affiliated Hospital of Nanchang University

AIM: To assess the effect of Helicobacter pylori(H. pylori) infection on metabolic parameters in Mongolian ***: A total of 40 male, 5- to 8-wk-old, specific-pathogen-free Mongolian gerbils(30-50 g) were randomly allocated into two groups: a control group(n = 20) and an H. pylori group(n = 20). After a two-week acclimation period, the control group was administered Brucella broth and the H. pylori group was challenged intra-gastrically five times every other day with approximately 109/CFU H. pylori ATCC43504(Cag A+, Vac A+). Each group was then divided into two subgroups, which were sacrificed at either 6 or 12 mo. The control and H. pylori subgroups each contained 10 Mongolian gerbils. Body weight, abdominal circumference, and body length were measured, and body mass index(BMI) and Lee's index were calculated. Biochemical assays were used to detect serum indexes, including glucose, glycated hemoglobin(GHb), glycated hemoglobin A1c(Hb A1c), triacylglycerol, and total cholesterol, using an automatic biochemistry analyzer. Inflammatory cytokines, including interleukin(IL)-1β, IL-2, IL-4,IL-10, IL-12, tumor necrosis factor-α(TNF-α) and interferon(IFN)-g, were assayed using ELISA. The expression of insulin and insulin-like growth factor 1(IGF-1) was detected by immunohistochemistry, and islet apoptosis was measured using the terminal deoxynucleotidyl transferase-mediated d UTP nick end labeling(TUNEL) ***: At each time point, body weight, abdominal circumference, BMI, and Lee's index were increased after H. pylori infection. However, these differences were not significant. H. pylori infection significantly increased the GHb(5.45 ± 0.53 vs 4.98 ± 0.22, P < 0.05) and Hb A1c(4.91 ± 0.61 vs 4.61 ± 0.15, P < 0.05) levels at 12 mo. We observed no significant differences in serum biochemical indexes, including fasting blood glucose, triacylglycerol and total cholesterol, at 6 or 12 mo after infection. H. pylori infection significantly increased the express

关键词： Helicobacter pylori Glycated hemoglobin A1c Glucos