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Curcumin attenuates ochratoxin A and hypoxia co‑induced liver injury in grass carp(Ctenopharyngodon idella)by dual targeting endoplasmic reticulum stress and apoptosis via reducing ROS content

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Journal of Animal Science and Biotechnology 2025年第1期16卷 408-423页

作者： liangqin Wu Piao Zhao Pei Wu Weidan Jiang Yang Liu Hongmei Ren Xiaowan Jin Xiaoqiu Zhou Lin feng Animal Nutrition Institute Sichuan Agricultural UniversityChengdu 611130China Fish Nutrition and Safety Production University Key Laboratory of Sichuan Province Sichuan Agricultural UniversityChengdu 611130China Key Laboratory of Animal Disease-Resistance Nutrition Ministry of EducationMinistry of Agriculture and Rural AffairsKey Laboratory of Sichuan ProvinceChengduSichuan 611130China

Background Ochratoxin A(OTA)is a toxin widely found in aquafeed ingredients,and hypoxia is a common prob-lem in fish *** practice,aquatic animals tend to be more sensitive to hypoxia while feeds are contaminated with OTA,but no studies exist in this *** research investigated the multiple biotoxicities of OTA and hypoxia combined on the liver of grass carp and explored the mitigating effect of curcumin(CUR).Methods A total of 720 healthy juvenile grass carp(11.06±0.05 g)were selected and assigned randomly to 4 experi-mental groups:control group(without OTA and CUR),1.2 mg/kg OTA group,400 mg/kg CUR group,and 1.2 mg/kg OTA+400 mg/kg CUR group with three replicates each for 60 ***,32 fish were selected,divided into nor-moxia(18 fish)and hypoxia(18 fish)groups,and subjected to hypoxia stress for 96 *** CUR can attenuate histopathological damage caused by coming to OTA and hypoxia by reducing vacu-olation and nuclear *** alleviation of this damage was associated with the attenuation of apoptosis in the mitochondrial pathway by decreasing the expression of the pro-apoptotic proteins Caspase 3,8,9,Bax,and Apaf1 while increasing the expression of the anti-apoptotic protein Bcl-2,and attenuation of endoplasmic reticulum stress(ERS)by reducing grp78 expression and chop *** may be attributed to the fact that the addi-tion of CUR increased the levels of catalase(CAT)and glutathione reductase(gSH),increased antioxidant capacity,and ensured the proper functioning of respiratory chain complexes I and II,which in turn reduced the high produc-tion of reactive oxygen species(ROS),thus alleviating apoptosis and *** In conclusion,our data demonstrate the effectiveness of CUR in attenuating liver injury caused by the combination of OTA and *** study confirms the feasibility and efficacy of adding natural products to mitigate toxic damage to aquatic animals.

关键词： Apoptosis Curcumin Endoplasmic reticulum stress grass carp Hypoxia Ochratoxin A Oxidative damage

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Prenatal ultrasonography and genetic analysis of fetal cleidocranial dysplasia:A case report

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World Journal of Clinical Cases 2025年第10期13卷 28-34页

作者： feng Wang Pei-feng Dai Wen-Juan gao Department of Ultrasonography Weifang People’s HospitalWeifang 261000Shandong ProvinceChina

BACKgROUND Cleidocranial dysplasia(CCD)is an infrequent clinical condition with an autosomal dominant inheritance *** is characterized by abnormal clavicles,patent sutures and fontanelles,supernumerary teeth,and short *** 60%-70%of patients with CCD have mutations in the RUNX family transcription factor 2 ***,prenatal diagnosis of CCD is difficult when the family history is *** SUMMARY We report a rare case of fetal CCD with an unknown family history,confirmed by prenatal ultrasonography and genetic testing at a gestational age of 16 *** genetic reports indicated that the fetus carried pathogenic mutations in the RUNX family transcription factor 2 gene(c.674g>A).After careful consideration,the pregnant woman and her family decided to continue the *** Definitive prenatal diagnosis of CCD should include family history,ultrasound diagnosis,and genetic analysis,especially if family history is unknown.

关键词： Cleidocranial dysplasia genetic analysis Ultrasonic diagnosis Prenatal Case report

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Support effect and confinement effect of porous carbon loaded tin dioxide nanoparticles in high-performance CO_(2) electroreduction towards formate

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Chinese Chemical Letters 2025年第1期36卷 597-602页

作者： Xingxing Jiang Yuxin Zhao Yan Kong Jianju Sun Shangzhao feng Xin Lu Qi Hu Hengpan Yang chuanxin He College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060China

Leveraging the interplay between the metal component and the supporting material represents a cornerstone strategy for augmenting electrocatalytic efficiency,e.g.,electrocatalytic CO_(2)reduction reaction(CO_(2)RR).Herein,we employ freestanding porous carbon fibers(PCNF)as an efficacious and stable support for the uniformly distributed SnO_(2)nanoparticles(SnO_(2)PCNF),thereby capitalizing on the synergistic support effect that arises from their strong *** one hand,the interaction between the SnO_(2)nanoparticles and the carbon support optimizes the electronic configuration of the active *** interaction leads to a noteworthy shift of the d-band center toward stronger intermediate adsorption energy,consequently lowering the energy barrier associated with CO_(2)*** a result,the Sn O_(2)PCNF realizes a remarkable CO_(2)RR performance with excellent selectivity towards formate(98.1%).On the other hand,the porous carbon fibers enable the uniform and stable dispersion of SnO_(2)nanoparticles,and this superior porous structure of carbon supports can also facilitate the exposure of the SnO_(2)nanoparticles on the reaction interface to a great ***,adequate contact between active sites,reactants,and electrolytes can significantly increase the metal utilization,eventually bringing forth a remarkable7.09 A/mg mass *** work might provide a useful idea for improving the utilization rate of metals in numerous electrocatalytic reactions.

关键词： CO_(2)electroreduction Support effect Porous carbon fiber Formate Mass activity

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The effects of 17β-trenbolone and bisphenol A on sexual behavior and social dominance via the hypothalamic-pituitary-gonadal axis in male mice

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Journal of Environmental Sciences 2025年第5期151卷 54-67页

作者： Xiang Zuo Minghe Sun Huijuan Bai Shuhui Zhang Jialu Luan Qian Yu Zhenhua Fu Qili Zhao Mingzhu Sun Xin Zhao Xizeng feng College of Life Science State Key Laboratory of Medicinal Chemical BiologyThe Key Laboratory of Bioactive MaterialsMinistry of EducationNankai UniversityTianjin 300071China Institute of Robotics&Automatic Information System College of Artificial IntelligenceNankai UniversityTianjin 300071China

17β-Trenbolone(17-TB)is well documented as an environmental endocrine disruptor in aquatic biological studies,but its effects on mammals remain poorly ***,17-TB acts as a hormone with properties similar to testosterone,and the consequences of juvenile exposure on adult social behavior remain *** A(BPA)acts as an estrogen-like hormone,compared to ***-week-old male Balb/c mice were exposed orally to 17-TB(100μg/(kg·day))and BPA(4 mg/(kg·day))for 28 *** of social interactions and a three-chamber test showed that 17-TB increased virility in male mice,intensified both male and female sexual behavior,and attracted and accepted female *** also increased social dominance through tube tests inmalemice and markedly activated the c-Fos^(+)immune response in themedial prefrontal cortex(mPFC)and basal amygdala(BLA).ELISA data showed that 17-TB and BPA exposure significantly affected serum gonadotropin-releasing hormone(gnRH),growth hormone(gH),estradiol(E2),and luteinizing hormone(LH)levels,as well as testicular lesions and androgen receptor(ARβ)and estrogen receptor(ERα)*** transcriptomic analysis further confirmed that could disrupt steroid synthesis and linoleic acid-related biometabolic *** findings suggest the influence of 17-TB and BPA exposure on sexual behavior and fertility in male mice,possibly through modulation of the hypothalamic-pituitary-gonadal *** study provides insights relevant to human reproductive health and neuro-social behavioral research,and the potential risk of environmental disturbances should not be overlooked.

关键词： 17β-Trenbolone(17-TB) Bisphenol A(BPA) hypothalamic-pituitary-gonadal axis(HPg) Sex hormones Social dominance Sexual behavior

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Spatial-temporal distribution and emission of urban scale air pollutants in Hefei based on Mobile-DOAS

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Journal of Environmental Sciences 2025年第5期151卷 238-251页

作者： Zhidong Zhang Pinhua Xie Ang Li Min Qin Jin Xu Zhaokun Hu Xin Tian feng Hu Yinsheng Lv Jiangyi Zheng Youtao Li School of Environmental Science and Optoelectronic Technology University of Science and Technology of ChinaHefei 230026China Key Laboratory of Environmental Optics and Technology Anhui Institute of Optics and Fine MechanicsHefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China University of Chinese Academy of Sciences Beijing 100049China Information Materials and Intelligent Sensing Laboratory of Anhui Province Institutes of Physical Science and Information TechnologyAnhui UniversityHefei 230601China

As a significant city in the Yangtze River Delta regions,Hefei has experienced rapid changes in the sources of air pollution due to its high-speed economic development and urban ***,there has been limited research in recent years on the spatial-temporal distribution and emission of its atmospheric *** address this,this study conducted mobile observations of urban roads using the Mobile-DOAS instrument from June 2021 to May *** monitoring results exhibit a favourable consistent with TROPOMI satellite data and ground monitoring station ***,there were pronounced seasonal variations in air ***,high concentration of HCHO and NO_(2)were closely associated with traffic congestion on roadways,while heightened SO_(2)levels were attributed to winter heating and industrial *** study also revealed that with the implementation of road policies,the average vehicle speed increased by 95.4%,while the NO concentration decreased by 54.4%.In the estimation of urban NO_(x)emission flux,it was observed that in temporal terms,compared with inventory data,the emissions calculated viamobile measurements exhibitedmore distinct seasonal patterns,with the highest emission rate of 349 g/sec in winter and the lowest of 142 g/sec in *** spatial terms,the significant difference in emissions between the inner and outer ring roads also suggests the presence of the city’s primary NO_(x)emission sources in the area between these two *** study offers data support for formulating the next phase of air pollution control measures in urban areas.

关键词： Mobile-DOAS HCHO NO_(2) SO_(2) Spatial-temporal distribution NOx emission

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High summer background O_(3)levels in the desert of northwest China

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Journal of Environmental Sciences 2025年第5期151卷 516-528页

作者： Xinbing Ren Fang Wang Bayi Wu Shaoting Zhang Lei Zhang Xingjun Zhou Yuanzhe Ren Yongjing Ma feng Hao Yongli Tian Jinyuan Xin Key Laboratory of Atmospheric Environment and Extreme Meteorology Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry(LAPC) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China Inner Mongolia Environmental Monitoring Center Alashan Substation 750300China Inner Mongolia Environmental Monitoring Center Hohhot 010011China Laboratory for Supervision and Evaluation of Pollution Reduction and Carbon Reduction in Arid and Semi-Arid Regions Inner Mongolia Environmental Monitoring CenterHohhot 010011China

generally speaking,the precursors of ozone(O_(3)),nitrogen oxides and volatile organic compounds are very low in desert areas due to the lack of anthropogenic emissions and natural emissions,and thus O_(3)concentrations are relatively ***,high summer background concentrations of about 100μg/m^(3)or 60 ppb were found in the Alxa Desert in the highland of northwest China based on continuous summer observations from 2019 to 2021,which was higher than the most of natural background areas or clean areas in world for summer O_(3)background *** high O_(3)background concentrations were related to surface features and ***-intensity anthropogenic activity areas in desert areas can cause increased O_(3)concentrations or pollution,but also generated O_(3)depleting substances such as nitrous oxide,which eventually reduced the regional O_(3)baseline *** dioxide(NO2)also had a dual effect on O_(3)generation,showing promotion at low concentrations and inhibition at high *** addition,sand-dust weather reduced O_(3)clearly,but O_(3)eventually stabilized around the background concentration values and did not vary with sand-dust particulate matter.

关键词： Alxa Desert O_(3)background concentration Anthropogenic effect Sand-dust weather Northwest China

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Spatial Patterns and Controlling Factors of Soil Organic Carbon and Total Nitrogen in the Three River Headwaters Region,China

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Chinese geographical Science 2025年第1期35卷 131-148页

作者： CUI Qiao LI Zongxing feng Qi ZHANg Baijuan ZHAO Yue Observation and Research Station of Eco-Hydrology and National Park by Stable Isotope Tracing in Qilian Mountains/Key Laboratory of Ecological Safety and Sustainable Development in Arid Lands Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China College of geography and Environmental Science Northwest Normal UniversityLanzhou 730070China

The alpine ecosystem has great potential for carbon *** organic carbon(SOC)and total nitrogen(TN)are highly sensitive to climate change,and their dynamics are crucial to revealing the effect of climate change on the structure,function,and services of the ***,the spatial distribution and controlling factors of SOC and TN across various soil layers and vegetation types within this unique ecosystem remain inadequately *** this study,256 soil samples in 89 sites were collected from the Three River Headwaters Region(TRHR)in China to investigate SOC and TN and to explore the primary factors affecting their distribution,including soil,vegetation,climate,and geography *** results show that SOC and TN contents in 0-20,20-40,40-60,and 60-80 cm soil layers are 24.40,18.03,14.04,12.40 g/kg and 2.46,1.90,1.51,1.17 g/kg,respectively;with higher concentrations observed in the southeastern region compared to the northwest of the ***-way analysis of variance reveals that SOC and TN levels are elevated in the alpine meadow and the alpine shrub relative to the alpine steppe in the 0-60 cm soil *** structural equation model explores that soil water content is the main controlling factor affecting the variation of SOC and ***,the geography,climate,and vegetation factors notably indirectly affect SOC and TN through soil ***,it can effectively improve soil water and nutrient conditions through vegetation restoration,soil improvement,and grazing management,and the change of SOC and TN can be fully understood by establishing monitoring networks to better protect soil carbon and nitrogen.

关键词： controlling factors different soil layers soil organic carbon(SOC) soil total nitrogen(TN) alpine ecosystem the Three River Headwaters Region(TRHR),China

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Atmospheric reductive catalytic fractionation of lignocellulose integrated with one-pot catalytic conversion of carbohydrate yielding valuable lignin monomers and platform chemicals from corn straw

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green Energy & Environment 2025年第1期10卷 161-172页

作者： Meng-Ying Liu Zhe-Hui Zhang Xue-Qi Wang Qian Sun Chen Zhang Yu Li Zhuohua Sun Katalin Barta feng Peng Tong-Qi Yuan State Key Laboratory of Efficient Production of Forest Resources Beijing Forestry UniversityBeijing100083China Beijing Key Laboratory of Lignocellulosic Chemistry Beijing Forestry UniversityBeijing100083China Department of Chemistry Organic and Bioorganic ChemistryUniversity of GrazHeinrichstrasse 28/II8010 GrazAustria

Developing a cost-effective and environmentally friendly process for the production of valuable chemicals from abundant herbal biomass receives great attentions in recent ***,taking advantage of the“lignin first”strategy,corn straw is converted to valuable chemicals including lignin monomers,furfural and 5-methoxymethylfurfural via a two steps *** key of this research lies in the development of a green and low-cost catalytic process utilizing magnetic Raney Ni catalyst and high boiling point ethylene *** utilization of neat ethylene glycol as the sole slovent under atmospheric conditions obviates the need for additional additives,thereby facilitating the entire process to be conducted in glass flasks and rendering it highly convenient for scaling *** the initial step,depolymerization of corn straw lignin resulted in a monomer yield of 18.1 wt%.Subsequently,in a dimethyl carbonate system,the carbohydrate component underwent complete conversion in a one-pot process,yielding furfural and 5-methoxymethylfurfural as the primary products with an impressive yield of 47.7%.

关键词： Atmospheric reductive catalytic fractionation Corn straw Ethylene glycol Raney Ni 5-Methoxymethylfurfural

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Amino-functionalized and Na+ pre-intercalated three-dimensional Ti_(3)C_(2)T_(x) film aerogel with excellent electrochemical performances for supercapacitor

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Nano Research 2025年第2期18卷 328-336页

作者： Xinhui Jin Dejie Mo Lirong feng Dong Wang Baolian Su Xiaohui guo Key Lab of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education The College of Chemistry and Materials ScienceNorthwest UniversityXi’an 710069China Department of inorganic chemistry University of Namur61 rue de BruxellesB-5000 NamurBelgium

Precise modulation of the pore structure and modification of the surface groups(–NH_(2))of MXene aerogels by the solid foaming method in combination with Na^(+)pre intercalation can significantly increase the layer spacing and change the electronic structure of MXene,thereby significantly optimizing its electrochemical *** three dimensional(3D)network structure provides numerous active sites on the surface of MXene and provides more ion transfer pathways and the large layer spacing allows electrolyte ions fast transport and the surface groups provide more active sites for the pseudocapacitive *** a result,the prepared Na Ti_(3)C_(2)T_(x)(where T is–O,–OH,–F,and/or–NH_(2),and x represents the number of such groups)film aerogel delivers a high mass specific capacitance of 560 F·g^(-1) and excellent cycling performance of 94.5%capacitance retention after 12,000 cycles in 0.5 M H_(2)SO_(4).In addition,the flexible all-solid state supercapacitor(ASC)composed of MXene film electrodes has excellent specific capacitance~277 F·g^(-1) and high energy density~52.8 Wh·kg^(-1) at 1600 W·kg^(-1).Therefore,this work not only proposes a feasible synthetic method that can precisely regulate the pore structure and surface features of film aerogels,but also demonstrates the broad application prospects of aerogel materials in wearable power devices.

关键词： MXene aerogel intercalation supercapacitors capacitance

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Experimental demonstration of 220-gHz terahertz signals wireless transmission over 4.6 km

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Science China(Information Sciences) 2025年第1期68卷 386-388页

作者： Yi WEI Jianjun YU Mingxu WANg Xiongwei YANg Qiutong ZHANg Jingwen TAN Bing ZHANg Ying WU Yang HAN Peng TIAN Wen ZHOU Kaihui WANg feng ZHAO State Key Laboratory of ASIC and System Key Laboratory for Information Science of Electromagnetic Waves (MoE)School of Information Science and Technology Fudan University School of Electronic Engineering Xi'an University of Posts and Telecommunications

The advancement of terahertz (THz) communication technology drives the evolution of wireless communication systems,offering novel pathways and technical means for the development of future 6g communication *** wireless communication systems are often constrained by bandwidth limitations of electronic devices in high frequency ***,THz communication technology leverages the characteristics of electromagnetic waves to transcend these limitations,enabling communication athigher frequencies and wider bandwidths.

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