检索结果-南通市图书馆

A novel indocyanine green-based fluorescent marker for guiding surgical tumor resection

Journal of Innovative Optical Health Sciences 2021年第3期4卷 77-87页

作者： Jiawei Ge Justin d.Opfermann Hamed Saeidi Katherine A.Huenerberg christopher d.badger Jaepyeong Cha Martin J.Schnermann Arjun S.Joshi Axel Krieger department of Mechanical Engineering Johns Hopkins University BaltimoreMD 21218USA department of Mechanical Engineering University of Maryland College Park MD 20742USA Sheikh Zayed Institute for Pediatric Surgical Innovation Children's National Hospital WashingtonDC 20010USA department of Pathology George Washington University WashingtonDC 20052USA division of Otolaryngology-Head and Neck Surgery George Washington University Washington DC 20052USA Chemical Biology Laboratory Center for Cancer Research National Cancer InstituteNational Institutes of HealthFrederickMD 21702USA

Surgical tumor resection is a common approach to cancer *** Ink tattoos are widely used to aid tumor resection by localizing and mapping the tumor edge at the ***,India Ink tattoos are easily obscured during electrosurgical resection,and fade in intensity over *** this work,a novel near-infrared(NIR)fluorescent marker is introduced as an *** NIR marker was made by mixing indocyanine green(ICG),biocompatible cyanoacrylate,and *** marking strategy was evaluated in a chronic ex vivo feasibility study using porcine tissues,followed by a chronic in vivo mouse study while compared with India *** both studies,signal-to-noise(SNR)ratios and dimensions of the NIR markers and/or India Ink over the study period were calculated and *** was performed on the last day of the mouse study after mice were euthanized,and SNR ratios and dimensions were quantified and *** was performed at all injection sites and slides were examined by a *** proposed NIR marker achieved(i)consistent visibility in the 26-day feasibility study and(ii)improved durability,visibility,and biocompatibility when compared to traditional India Ink over the six-week period in an in vivo mouse *** effects persist after electrocautery whereas the India Ink markers were *** use of a NIR fluorescent presurgical marking strategy has the potential for intraoperative tracking during long-term treatment protocols.

关键词： Near-infrared fluorescent marker surgical tumor resection fluorescence-guided sur-gery electrosurgery India ink

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

引用

Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： christopher J.O’Connell Matthew J.Robson department of Genetics College of MedicineHarvard UniversityBostonMAUSA James L.Winkle College of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Jet flows from bubbles during subcooled pool boiling on micro wires

引用

Science China(Technological Sciences) 2005年第4期48卷 385-402页

作者： d. M. christopher Laboratory of Phase Change and Interfacial Transport Phenomena Department of Thermal Engineering Tsinghua University Beijing 100084 China

An experimental investigation was conducted on subcooled nucleate boiling on ultra-small wires having diameters of 25―100 μm. High-speed photography and laser PIV (Particle Image Velocimetry) technology were used to visually observe the bubble dynamics. For highly subcooled boiling at moderate heat fluxes, the bubbles generally remained attached to the micro heating wires and bubble-top jet flows were clearly observed. Smaller bubbles usually had stronger bubble-top jet flows, while larger bubbles seemed to produce multi-jet flows. The structures of the bubble-top jet flows, as well as multi-jet flows, were proposed from the experimental observation. A model was developed to describe jet flow phenomena from bubbles on micro wires. Numerical simulations for bubbles having diameter of 0.03 and 0.06 mm showed that both the bubble-top and multi-jet flows were induced by a strong Marangoni effect due to high temperature gradients near the wire. The predicted velocity magnitudes and flow structures agreed very well with experimental measurements. The bubble size relative to the wire is an important factor affecting the jet flow structure. For a 0.03 mm bubble on a 0.1 mm wire, only a bubble-top jet flow forms, while a complex multi-jet flow pattern forms around the bubble with a weak bubble-top jet and two side jet flows for a 0.06 mm bubble.

关键词： subcooled boiling, bubble, multi-jet, jet flow, PIV, Marangoni, CFd.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

On a connectedness principle of Shokurov-Kollr type

引用

Science China Mathematics 2019年第3期62卷 411-416页

作者： christopher d.Hacon Jingjun Han department of Mathematics University of Utah Beijing International Center for Mathematical Research Peking University

Let(X, ?) be a log pair over S, such that-(KX+ ?) is nef over S. It is conjectured that the intersection of the non-klt(non Kawamata log terminal) locus of(X, ?) with any fiber Xs has at most two connected components. We prove this conjecture in dimension no greater than 4 and in arbitrary dimension assuming the termination of klt flips.

关键词： minimal model program non-klt locus connectedness

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Obstructive sleep apnea syndrome and fatty liver: Association or causal link?

引用

World Journal of Gastroenterology 2010年第34期16卷 4243-4252页

作者： Mohamed H Ahmed christopher d Byrne Chemical Pathology department Southampton University Hospital NHS Trust Southampton SO16 6YD United Kingdom Endocrinology and Metabolism DOHaD Division University of Southampton and Southampton University Hospitals Trust Southampton SO16 6YD United Kingdom

Obstructive sleep apnea (OSA) is a complex disorder that consists of upper airway obstruction, chronic intermittent hypoxia and sleep fragmentation. OSA is well known to be associated with hypoxia, insulin resistance and glucose intolerance, and these factors can occur in the presence or absence of obesity and metabolic syndrome. Although it is well established that insulin resistance, glucose intolerance and obesity occur frequently with non-alcoholic fatty liver disease (NAFLd), it is now becoming apparent that hypoxia might also be important in the development of NAFLd, and it is recognized that there is increased risk of NAFLd with OSA. This review discusses the association between OSA, NAFLd and cardiovascular disease, and describes the potential role of hypoxia in the development of NAFLd with OSA.

关键词： Sleep apnea syndrome Hyperlipidemia Non-alcoholic fatty liver disease Insulin resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Experimental Study of High Moisture Content Gas Flow Across a Cylinder at Moderate Reynolds Numbers

引用

Tsinghua Science and Technology 2003年第5期8卷 598-604页

作者： d.M.christopher 郭亮 department of Thermal Engineering

The Nusselt number for cross flow of a mixture of air and vapor over a cylinder was measured at moderate Reynolds numbers (30007000) for temperatures from 300℃ to 700℃ and for vapor mass fractions of 0.180.35. Results are also presented for a set of three cylinders aligned perpendicular to the flow for the same range of conditions. The effect of the vapor concentration and temperature on the convection coefficients was investigated to develop a modified Zhukauskas correlation. The results show that the Nusselt number increases as the moisture content increases and that the increase is more than could be accounted for by typical models for the property variations of mixtures. The exponent of the vapor concentration term in the modified correlation is 0.145 for the entire data set indicating the importance of the property variation due to the moisture content.

关键词： high moisture content cross flow convection coefficients heat exchangers

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tuning periodicity of polymer-decorated carbon nanotubes

引用

Science China Chemistry 2012年第5期55卷 802-807页

作者： LAIRd Eric d. LI christopher Y. A. J. drexel Nanotechnology Institute and department of Materials Science and Engineering Drexel University Philadelphia Pennsylvania 19104 USA

Carbon nanotube (CNT) is one of the most extensively investigated nanomaterials. Patterning soft matter such as liquid crystals and polymers on CNTs could potentially enable various applications for CNTs. We have demonstrated that controlled polymer crystallization using CNTs as the 1d nucleation sites can lead to periodically functionalized CNTs. Here we show that selected crystalline block copolymers can be periodically decorated along CNTs. This facile technique opens a gateway to periodic patterning on 1-d nanomaterials.

关键词： polymer crystallization carbon nanotube block copolymers

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synovial osteochondromatosis of the temporomandibular joint: A case report

引用

World Journal of Otorhinolaryngology 2019年第2期8卷 12-18页

作者： Nahir Romero Collin F Mulcahy Stephanie Barak Muhammed F Shand christopher d.badger Arjun S Joshi department of Surgery Division of OtolaryngologyHead and Neck SurgeryGeorge Washington University HospitalWashingtonDC 20037United States department of Pathology George Washington University HospitalWashingtonDC 20037United States George Washington University School of Medicine and Health Sciences WashingtonDC 20037United States

BACKGROUNd Synovial osteochondromatosis is a rare but benign condition that can result in significant impairment of joint *** case report documents an uncommon presentation of this disorder occurring within the temporomandibular joint,causing the patient significant pain,trismus,and difficulty with daily activities such as eating and speaking.A review of the literature including disease mechanisms and previously documented cases is included to provide comprehensive background for clinical *** SUMMARY A 48-year-old male patient presented with a 3-mo history of trismus,crepitus with jaw movement and significant pain while *** examination revealed a firm mass and tenderness to palpation at the right temporomandibular *** workup revealed a bilobed mass extending into the joint space as well as significant bony erosion of the glenoid *** patient underwent mass excision with joint reconstruction and pathology revealed synovial *** patient reported significant improvement in his symptoms *** This report outlines the investigative approach and treatment course of synovial *** positive outcome following surgical intervention in this case emphasizes the importance of interdisciplinary collaboration and the potential for improvement in quality of life of this patient population.

关键词： Osteochondromatosis Temporomandibular joint Mandible Resection Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Modeling visitor use on high elevation mountain trails: An example from Longs Peak in Rocky Mountain National Park, USA

引用

Journal of Mountain Science 2019年第12期16卷 2882-2893页

作者： david PETTEBONE Ashley d'ANTONIO Abigail SISNEROS-KIdd christopher MONZ National Park Service Natural Resources Stewardship and ScienceEnvironmental Quality DivisionSocial Science Program80525 Fort CollinsColoradoUSA Oregon State University Department of Forest Ecosystems and Society97331 CorvallisOregonUSA Utah State University Quinney College of Natural Resources84322 LoganUtahUSA Current Affiliation:University of Wyoming Haub School of Environment and Natural Resources82072 LaramieWyomingUSA

Increasing use on mountain summits has both social and ecological *** numbers of visitors climbing mountain summits can be a safety issue,particularly in areas where terrain or elevation leads to queueing that may cause time *** visitor use levels at site specific locations en route to summits is needed to understand the potential benefits and impacts of visitor use in these ***,it can be difficult to obtain reliable and robust data to estimate use and develop statistical relationships because of the remote and harsh climates on mountain summits,as well as the financial and personnel requirements involved to collect the data in remote *** 2015,data were collected on the higher stretches of the Keyhole Route on Longs Peak in Rocky Mountain National Park,USA(RMNP)to better understand use levels near the summit and to explore potential statistical relationships to trailhead use data that are relatively easy to *** statistical relationships from robust regression analyses were found between trailhead use counts and daily and hourly use totals on the"Homestretch"which is a final section of the Keyhole ***,a strong statistical relationship was found between total daily use and maximum hourly use on the *** results suggest that trailhead counts are an accurate and reliable means from which to estimate use levels on upper portions of the Keyhole ***,this research demonstrates the usefulness of an approach using proxy variables to estimate visitor use along remote peaks where data collection can be *** types of data can elucidate various options and decisions for park management teams who are charged with deciding if and how to manage high use areas.

关键词： Visitor use Mountain summits National parks Use estimation Recreation use Proxy variables

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Protecting miners from coal bursts during development above historic mine workings in Harlan County,KY

引用

International Journal of Mining Science and Technology 2021年第1期31卷 111-116页

作者： christopher Mark Mine Safety and Health Administration PittsburghPA 15236USA

In order to reach a large,untapped reserve of high-quality coal,d8 Cloverlick Mine proposed to mine a corridor nearly 600 m deep beneath the Benham Spur of Black Mountain,Kentucky’s highest peak.d8 Cloverlick Mine was extracting the Owl seam,but the corridor’s route lay approximately 20 m above century-old mine workings in the C–(darby)*** to the concern,three serious coal bursts had recently occurred in nearby Owl seam *** of the old workings seemed to indicate that the underlying C–seam had been fully ***,two of the coal bursts had occurred above areas where the C–Seam was also shown as mined *** Safety and Health Administration(MSHA)Technical Support therefore investigated the records of past mining to better understand the old mine *** conditions observed in current Owl seam workings were also compared with the maps of the old C–seam *** study concluded that the presence of hazardous underlying remnants could not be ruled *** mitigate the burst risk,d8 Cloverlick Mine adopted a strategy of stress probe drilling.A self-propelled coal drill was used to auger 11.5-m-long,small diameter holes in advance of *** each hole was drilled,the cuttings were measured to detect the presence of highly stressed *** the crossing was successfully completed without incident.

关键词： Coal bursts Underground mining Room-and-pillar destressing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：