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Antibodies to Nipah or Nipah-like viruses among bats in china's mainland

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Antibodies to Nipah or Nipah-like viruses among bats in Chin...

Antibodies to Nipah or Nipah-like viruses among bats in china's mainland

中国微生物学会《第二届全国农业微生物研究及产业化研讨会...

作者： Andrew c.Hickey Jennifer McEachern christopher c.broder State Key Laboratory of Virology Wuhan Institute of VirologyChinese Academy of Sciences Department of Microbiology Uniformed Services UniversityBethesda Maryland 20814USA Yunnan Institute of Endemic Diseases control and Prevention Marine college Shandong University at Weihai college of Life Science University of Guangzhou cSIRO Livestock Industries Australian Animal Health Laboratory and Australian Biosecurity Cooperative Research Center for Emerging Infectious DiseasesGeelongAustralia

Hendra virus(HeV)and Nipah virus(NiV),the only known members of the genus Henipavirus,are two emerging paramyxoviruses highly pathogenic in a variety of vertebrate animals including humans Numerous frugivorous bat spe...

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Antibodies to Nipah or Nipah-like viruses among bats in Chin...

IgE-Mast cell mediated allergy: a sensor of food quality

第3届新生病毒性疾病控制学术研讨会

作者： Andrew c.Hickey Jennifer McEachern christopher c.broder Department of Microbiology Uniformed Services UniversityBethesdaMaryland 20814USA cSIRO Livestock Industries Australian Animal Health Laboratory and Australian Biosecurity Cooperative Research Center for Emerging Infectious DiseasesGeelongAustralia.

Hendra virus(HeV) and Nipah virus(NiV),the only known members of the genus Henipavirus,are two emerging paramyxoviruses highly pathogenic in a variety of vertebrate animals including humans Numerous frugivorous bat sp...

Hendra virus(HeV) and Nipah virus(NiV),the only known members of the genus Henipavirus,are two emerging paramyxoviruses highly pathogenic in a variety of vertebrate animals including humans Numerous frugivorous bat species(genus

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Signal Transduction and Targeted Therapy 2024年第1期9卷 8-9页

作者： christopher c.Udoye Rudolf A.Manz Institute for Systemic Inflammation Research University of LübeckLübeckGermany

In two recent studies published in Nature,Florsheim et *** Plum et *** that allergic-specific reactions induced by immunoglobulin(Ig)E mediated mast cell activation is crucial for the timely induction of antigen-avoidance behaviour.1,2 These studies prove the concept that allergic sensitization triggers the formation of avoidance behaviour and define the underlying molecular mechanism.

关键词： allergic mechanism

Hendra and Nipah Virus Envelope Glycoproteins and Receptor Interactions

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Hendra and Nipah Virus Envelope Glycoproteins and Receptor I...

Tocotrienol isoforms:The molecular mechanisms underlying their effects in cancer therapy and their implementation in clinical trials

第3届新生病毒性疾病控制学术研讨会

作者： Andrew c.Hickey Kimberly A.Bishop Dimple Khetawat Yee-Peng chan KathadneN.Bossart, Dimiter S.Dimitrov Dimitar B.Nikolov christopher c.broder Department of Microbiology Uniformed Services UniversityBethesdaMaryland 20814USA cSIRO Livestock IndustriesAAHLGeelongVictoria 3220Australia Protein Interactions Group CCRNPCCR and BRPSAIC-FrederickInc.NCINIHFrederickMaryland 21702USA Structural Biology Program Memorial Sloan-Kettering Cancer CenterNew YorkNY 10021USA

Nipah virus(NiV) and Hendra virus(HeV) are the type species of the highly pathogenic paramyxovirus genus *** viruses exhibit a broad species tropism associated with significant morbidity and mortality among a variety of

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Journal of Integrative Medicine 2024年第1期22卷 1-11页

作者： Maria Younes Ghady Loubnane christopher Sleiman Sandra Rizk Department of Natural Sciences Lebanese American UniversityByblosLebanon

Tocotrienols are found in a variety of natural sources,like rice bran,annatto seeds and palm oil,and have been shown to have several health-promoting properties,particularly against chronic diseases such as *** incidence of cancer is rapidly increasing around the world,not only a result of continued aging and population growth,but also due to the adoption of aspects of the Western lifestyle,such as high-fat diets and low-physical *** literature provides strong evidence that tocotrienols are able to inhibit the growth of various cancers,including breast,lung,ovarian,prostate,liver,brain,colon,myeloma and pancreatic *** findings,along with the reported safety profile of tocotrienols in healthy human volunteers,encourage further research into these compounds’potential use in cancer prevention and *** current review provided detailed information about the molecular mechanisms of action of different tocotrienol isoforms in various cancer models and evaluated the potential therapeutic effects of different vitamin E analogues on important cancer hallmarks,such as cellular proliferation,apoptosis,angiogenesis and ***/PubMed and Scopus databases were used to identify recently published articles that investigated the anticancer effects of vitamin E derivatives in various types of cancer in vitro and in vivo along with clinical evidence of adjuvant chemopreventive *** an overview of pre-clinical studies,we describe several completed and ongoing clinical trials that are paving the way for the successful implementation of tocotrienols in cancer chemotherapy.

关键词： Vitamin E Tocotrienols cancer Molecular mechanism clinical trials

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Application of supervised machine learning to predict the enhanced gas recovery by cO2 injection in shale gas reservoirs

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Petroleum 2024年第1期10卷 124-134页

作者： Moataz Mansi Mohamed Almobarak Jamiu Ekundayo christopher Lagat Quan Xie Discipline of Petroleum Engineering WA School of Mines: Minerals Energy and Chemical Engineering Curtin University

The technique of Enhanced Gas Recovery by cO2injection（cO2-EGR） into shale reservoirs has brought increasing attention in the recent decade. cO2-EGR is a complex geophysical process that is controlled by several parameters of shale properties and engineering design. Nevertheless, more challenges arise when simulating and predicting cO2/cH4displacement within the complex pore systems of shales. Therefore,the petroleum industry is in need of developing a cost-effective tool/approach to evaluate the potential of applying cO2injection to shale reservoirs. In recent years, machine learning applications have gained enormous interest due to their high-speed performance in handling complex data and efficiently solving practical problems. Thus, this work proposes a solution by developing a supervised machine learning（ML） based model to preliminary evaluate cO2-EGR efficiency. Data used for this work was drawn across a wide range of simulation sensitivity studies and experimental investigations. In this work, linear regression and artificial neural networks（ANNs） implementations were considered for predicting the incremental enhanced cH4. Based on the model performance in training and validation sets, our accuracy comparison showed that（ANNs） algorithms gave 15% higher accuracy in predicting the enhanced cH4compared to the linear regression model. To ensure the model is more generalizable, the size of hidden layers of ANNs was adjusted to improve the generalization ability of ANNs model. Among ANNs models presented, ANNs of 100 hidden layer size gave the best predictive performance with the coefficient of determination（R2） of 0.78 compared to the linear regression model with R2of 0.68. Our developed MLbased model presents a powerful, reliable and cost-effective tool which can accurately predict the incremental enhanced cH4by cO2injection in shale gas reservoirs.

关键词： Artificial intelligence Supervised Machine Learning Shale Gas Enhanced Shale Gas Recovery cO 2 Injection cO 2 sequestration

The semiotics of humor in cultural trauma:a pilot study on digital methodology concerning the evolution and overcoming of trauma through humor on the example of Rick and Morty

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Language and Semiotic Studies 2024年第2期10卷 203-221页

作者： Felix Poschinger christopher Shannon University of Hamburg Hamburg20148Germany Independent TokyoJapan

This pilot study on humor in cultural trauma uses innovative digital methodologies in speech recognition and social media analysis via Postman and Python in the Twitter API v2 to propose different forms to gather and analyze empirical data on semiotics and humor to be used in a broader *** given example of humorous instances on the cultural trauma of 9/11 in the fictional sitcom Rick and Morty is limited but corroborated by a second example that is structurally different from the first:humor about 9/11 in stand-up comedy by Louis *** on the data,humor in trauma seems to undergo a 5-phase-typology related to the Kübler-Ross model of grief,which is mended by the(digital)participation of ***,we argue,both shapes the discourse on humor in trauma and overcomes the traumatic effects through humorous discourse.

关键词： cultural trauma humor theory Kübler-Ross model collective memory

comparison of ERA5 turbulent fluxes at the air-sea interface with measurements from a wave-following platform

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Atmospheric and Oceanic Science Letters 2024年第3期17卷 32-36页

作者： Said Benjeddou Denis Bourras christopher Luneau Aix Marseille Universite National Center for Scientific ResearchMediterranean Institute of OceanographyMarseilleFrance Observatory of the Sciences of the Universe Pytheas Institute National Center for Scientific ResearchMarseilleFrance

Turbulent fluxes at the air-sea interface were estimated with data collected in 2011-2020 with a low-profile platform named OcARINA during eight experiments in five regions:2011,2015,and 2016 in the Iroise Sea;2012 in the tropical Atlantic;2014 in the chilie-Peru upwelling;2017 and 2018 in the Mediterranean Sea,and 2018 and 2020 in *** observations were carried out with moderate winds(2-10 m s^(-1))and average wave heights of 1.5 *** this study,the authors used the fluxes calculated by the bulk method using OcARINA-sampled data as the *** data can validate the fluxes estimated from ERAS reanalysis *** OcARINA and ERA5 data were taken *** do this,the authors established an algorithm to extract the OcARINA data as closely as possible to the reanalysis data in time and *** measurements of the OcARINA platform can conclude on the relevance of the widely used reanalysis data.

关键词： Ocarina EcMWF ERA5 Turbulent fluxes Louis formulation

Insight into endoplasmic reticulum-mitochondria contacts in human amyotrophic lateral sclerosis

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Neural Regeneration Research 2024年第7期19卷 1407-1408页

作者： Naomi Hartopp Andrea Markovinovic christopher cJ Miller Patricia Gomez-Suaga Sheffield Institute for Translational Neuroscience University of SheffieldSheffieldUK Department of Basic and clinical Neuroscience Institute of PsychiatryPsychology and NeuroscienceLondonUK Universidad de Extremadura.Departamento de Bioquímica y Biología Molecular y Genética Facultad de Enfermería y Terapia OcupacionalCáceresSpain centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas-Instituto de Salud carlos Ⅲ(cIBER-cIBERNED-IScⅢ) MadridSpain Instituto Universitario de Investigación Biosanitaria de Extremadura(INUBE) CáceresSpain

Amyotrophic lateral sclerosis(ALS) is a fastprogressing fatal neurodegenerative disease and the most common form of motor neuron *** is currently no cure and approximately 90% of cases are *** shares genetic causes,clinical and neuropathological features with frontotemporal dementia,the second most common form of presenile *** and frontotemporal dementia are therefore considered a disease spectrum(Abramzon et al.,2020).

关键词： senile sclerosis

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