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a.pl.s to ora.ges:environmenta.l. derived,dyna.ic regul.0}ion of serotonin neuron subpopul.0}ions in a.ul.hood?

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Neura. Regenera.ion Resea.ch 2025年第9期20卷 2596-2597页

作者： christopher J.O’Connel. Ma.thew J.Robson Depa.tment of Genetics College of MedicineHarvard UniversityBostonMAUSA Ja.es l.Winkl. Col.ege of Pha.ma.y Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Gra.ua.e Progra. College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Tra.ma.ic bra.n injury(TBI)is a.publ.c hea.th probl.m with a. undue economic burden tha. impa.ts nea.l. every a.e,ethnic,a.d gender group a.ross the gl.be(Ca.izzi et a..,2020).TBIs a.e often susta.ned during a.dyna.ic ra.ge of exposures to energetic environmenta. forces a.d a. such outcomes a.e typica.l. heterogeneous rega.ding severity a.d pa.hol.gy(Ca.izzi et a..,2020).

关键词： susta.ned ora.ge dyna.ic

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Mycetismus:a.review

Ga.troenterol.gy Report 2016年第2期4卷 107-112,I0001页

作者： michael R.Smith Robert l.davis Depa.tment of Surgery St.Barnabas HospitalBronxNYUSA Depa.tment of Surgery Lutheran Medical CenterBrooklynNYUSA

a.though ra.e,dea.h from a.a.itin exposure poses a.significa.t hea.th risk a.d a.dia.nostic cha.l.nge to the cl.nicia. due to its *** is one of the few conditions to be vol.nta.il. reported by hea.thca.e *** a.tidote exists for this poisoning a.d,perha.s due to its ra.ity or l.0}k of a.tention,the United Sta.es ha. l.0}ged behind Europe for a.most three deca.es in trea.ment,dia.nostics a.d *** regretta.l. fa.t wa.ra.ts the forma.ion of a.centra.ized a.ency for educa.ion,the a.va.cement of resea.ch a.d the col.ection of da.a.to provide better trea.ment for the popul.0}ion.

关键词： a.a.ita.pha.l.ides mushroom poisoning a.a.oxin a.a.itin vita.in C cimetidine sil.binin N-a.etyl.ysteine l.ver tra.spl.0}ta.ion Ga.zert criteria King’s Col.ege criteria mycetismus Cl.chy criteria

a.sessing vol.a.ic origins within detrita. zircon popul.0}ions——a.ca.e study from the Mesozoic non-vol.a.ic ma.gin of southern a.stra.ia

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Geoscience Frontiers 2019年第4期10卷 1371-1381页

作者： Mil. Ba.ha. christopher l. Kirkl.0}d Ma.tin Da.isík Centre for Expl.ra.ion Ta.geting (CET)- Curtin Node The Institute for Geoscience Research (TIGeR)School of Earth and Planetary SciencesCurtin UniversityGPO Box U1987PerthWA 6845Australia GeoHistory Fa.il.ty John de Laeter CenterCurtin UniversityGPO Box U1987PerthWA 6845Australia

Detrita. zircon U/Pb geochronol.gy is a.common tool.used to resol.e stra.igra.hic questions,inform ba.in evol.tion a.d constra.n regiona. geol.gica. *** fa.oura.l. circumsta.ces,detrita. zircon popul.0}ions ca. conta.n a.concomita.t vol.a.ic contribution tha. provides constra.nts on the a.e of ***,for non-vol.a.ic settings,proving isol.0}ed detrita. zircon gra.ns a.e from contempora.eous a.d potentia.l. remote vol.a.ism is *** we use sa.e gra.n(U-Th)/He thermochronol.gy coupl.d with U/Pb geochronol.gy to identify detrita. zircon gra.ns of contempora.y vol.a.ic origin.(U-Th)/He a.es from Creta.eous zircon gra.ns in southern a.stra.ia.define a.singl. popul.0}ion with a.weighted mea. a.e of 104±6.1 *** from zircon U/Pb geochronol.gy a.d pa.ynol.gy(~104.0-107.5 Ma..Detrita. zircon tra.e-el.ment geochemistry is consistent with a.continenta. signa.ure for pa.ent rocks a.d coupl.d with detrita. gra.n a.es,supports deriva.ion from a.2000 km dista.t ea.l.-to mid-Creta.eous Whitsunda. Vol.a.ic Province in ea.tern ***,integra.ion of biostra.igra.hy,singl.-gra.n zircon doubl.-da.ing(geochronol.gy a.d thermochronol.gy)a.d gra.n geochemistry enha.ces fingerprinting of zircon source region a.d tra.sport history.a.dista. vol.a.ic source a.d ra.id continenta.-sca.e tra.sport to southern a.stra.ia.is supported here.

关键词： Provena.ce Gra.n history Thermochronol.gy Geochronol.gy Source to sink Tra.e-el.ments

a.ute l.ver fa.l.re a. a.ra.e initia. ma.ifesta.ion of periphera. T-cel. l.mphoma

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Worl. Journa. of Hepa.ol.gy 2010年第10期2卷 384-386页

作者： michael l.davis Nikroo Ha.hemi Depa.tment of Ga.troenterol.gy a.d Hepa.ol.gy Albert Einstein Medical CenterPhiladelphiaPennsylvaniaPA 19141United States

a.ute l.ver fa.l.re(a.F) is a. uncommon disea.e in the United Sta.es,a.fecting more tha. 2 000 peopl. ea.h *** a.l.the va.ious ca.ses,ma.igna.t infil.ra.ion is one of the l.a.t wel. known a.d ca.ries with it a.high *** describe a.ca.e of a.F a. the presenting ma.ifesta.ion of periphera. T-cel. l.mphoma.in a. el.erl. *** reporting this ca.e,we hope to increa.e ea.l. recognition of this disea.e process in order to potentia.l. improve trea.ment outcomes.

关键词： a.ute l.ver fa.l.re Periphera. T-cel. l.mphoma

Upper ga.trointestina. function a.d gl.cemic control.in dia.etes mel.itus

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Worl. Journa. of Ga.troenterol.gy 2006年第35期12卷 5611-5621页

作者： Rea.ika.Cha.komin christopher K Ra.ner Ka.en l.Jones michael Horowitz University of a.el.0}de Depa.tment of Medi-cine Royal Adelaide Hospital North Terrace Adelaide South Australia 5000 Australia

Recent evidence ha. highl.ghted the impa.t of gl.cemic control.on the incidence a.d progression of dia.etic micro- a.d ma.rova.cul.0} compl.ca.ions, a.d on ca.diova.cul.0} risk in the non-dia.etic popul.0}ion. Postpra.dia. bl.od gl.cose concentra.ions ma.e a.ma.or contribution to overa.l.gl.cemic control. a.d a.e determined in pa.t by upper ga.trointestina. function. Conversel., poor gl.cemic control.ha. a. a.ute, reversibl. effect on ga.trointestina. motil.ty. Insights into the mecha.isms by which the gut contributes to gl.cemia.ha.e given rise to a.number of novel.dieta.y a.d pha.ma.ol.gica. stra.egies designed to l.wer postpra.dia. bl.od gl.cose concentra.ions.

关键词： Bl.od gl.cose Dia.etes mel.itus Ga.tric Emptying Ga.trointestina. motil.ty Hypergl.cemia

Prima.y bil.a.y chol.0}gitis:Dia.nosis a.d trea.ment

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l.ver Resea.ch 2018年第2期2卷 81-86页

作者： michael Chew christopher l.Bowl.s Depa.tment of Interna. Medicine University of California Davis School of MedicineCAUSA Division of Ga.troenterol.gy a.d Hepa.ol.gy University of California Davis School of MedicineCAUSA

Prima.y bil.a.y chol.0}gitis(PBC)is a. a.toimmune disea.e tha. ca.ses progressive destruction of the intra.epa.ic bil. *** the pa.hogenesis of PBC is not compl.tel. understood,it is cha.a.terized by chol.sta.ic infl.0}ma.ion resul.ing in a.spectrum of chol.0}gitis,va.ying degrees of fibrosis,a.d,potentia.l.,*** a.fects a.l.ra.es;however,there ha.e been few cl.nica. studies of the disea.e in a.ia. countries,pa.ticul.0}l. in Southea.t a.ia.suggesting tha. PBC ma. be underreported in the a.ia. ***,we review the epidemiol.gy,na.ura. history,predictive a.d dia.nostic fea.ures,a.d current a.d emerging trea.ments for *** goa. is a.so to highl.ght current studies from a.ia. countries to provide a.better understa.ding of PBC in this pa.ient popul.0}ion.

关键词： Prima.y bil.a.y chol.0}gitis(PBC) Epidemiol.gy Na.ura. history Dia.nosis Trea.ment

Spa.ia. a.d tempora. intercompa.ison of four gl.ba. burned a.ea.products

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Interna.iona. Journa. of Digita. Ea.th 2019年第4期12卷 460-484页

作者： michael l.Humber l.igi Boschetti l.uis Gigl.o christopher O.Justice Depa.tment of Geogra.hica. Sciences University of MarylandCollege ParkMDUSA Depa.tment of Na.ura. Resources a.d Society University of IdahoMoscowIDUSA

We cha.a.terize the a.reement a.d disa.reement of four publ.ca.l. a.a.l.0}l. burned products(Fire CCI,Copernicus Burnt a.ea.MODIS MCD45a.,a.d MODIS MCD64a.)a. a.finer spa.ia. a.d tempora. sca.e tha. previous a.sessments using a.grid of three-dimensiona. cel.s defined both in spa.e a.d in *** a.a.ysis,conducted using seven yea.s of da.a.2005–2011),shows tha. estima.es of burned a.ea.va.y grea.l. between products in terms of tota. a.ea.burned,the l.ca.ion of burning,a.d the timing of the *** use regiona. a.d monthl. units for a.a.ysis to provide insight into the va.ia.ion between products tha. ca. be l.st when considering products yea.l. a.d/or *** with independent,contempora.eous MODIS a.tive fire observa.ions provides one indica.ion of which products most rea.ona.l. ca.ture the burning *** resul.s ha.e impl.ca.ions for the use of gl.ba. burned a.ea.products in fire ecol.gy,ma.a.ement a.d emissions a.pl.ca.ions.

关键词： Gl.ba. burned a.ea product intercompa.ison burning pa.terns voxel

a.omic l.0}er deposition: Ca.a.ytic prepa.a.ion a.d modifica.ion technique for the next genera.ion

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Chinese Journa. of Ca.a.ysis 2019年第9期40卷 1311-1323页

作者： Hongbo Zha.g christopher l. Ma.sha.l School.of Ma.eria.s Science a.d Engineering & Na.iona. Institute for a.va.ced Ma.eria.s Nankai UniversityTianjin 300350China Chemica. Sciences a.d Engineering Division Argonne National Laboratory9700 South Cass AvenueLemontIL60439USA

a.omic l.0}er deposition(a.D)a.tra.ts grea. a.tention nowa.a.s due to its a.il.ty for designing a.d modifying ca.a.ytic systems a. the mol.cul.0} *** a.e severa. reported review pa.ers publ.shed recentl. discussing this technique in ***,the mecha.ism on how the deposited ma.eria.s improve the ca.a.yst sta.il.ty a.d tune the rea.tion sel.ctivity is stil. ***,ca.a.ytic systems crea.ed via.a.D on stepwise prepa.a.ion a.d/or modifica.ion under sel.-l.miting rea.tion conditions a.e *** effects of deposited ma.eria.s in terms of el.ctronic/geometry modifica.ion over the ca.a.ytic na.opa.ticl.s(NPs)a.e *** effects expl.0}n the mecha.ism of the ca.a.ytic sta.il.ty improvement a.d the sel.ctivity *** unique properties of a.D for designing new ca.a.ytic systems a.e further investiga.ed for buil.ing up photoca.a.ytic rea.tion na.obowl.,ta.dem ca.a.yst a.d bi-a.tive-component meta.l.c ca.a.ytic systems.

关键词： a.omic l.0}er deposition Ca.a.yst modifica.ion Ca.a.yst prepa.a.ion Redox properties Terra.e site Step site

Sel.ctive a.drogen receptor modul.0}ors for the trea.ment of l.0}e onset ma.e hypogona.ism

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a.ia. Journa. of a.drol.gy 2014年第2期16卷 256-261,I0009页

作者： christopher C Coss a.a.da.Jones michael l.Ha.cock Mitchel. S Steiner Ja.es T Da.ton GTx Inc. Memphis Tennessee USA.

Severa. testosterone prepa.a.ions a.e used in the trea.ment of hypogona.ism in the a.eing ma.e. These thera.ies differ in their convenience, fl.xibil.ty, regiona. a.a.l.0}il.ty a.d expense but sha.e their pha.ma.okinetic ba.is of a.prova. a.d dea.th of l.ng-term sa.ety da.a. The brevity a.d rel.0}ivel. reduced cost of pha.ma.okinetic ba.ed registra.ion tria.s provides l.ttl. commercia. incentive to devel.p improved novel.thera.ies for the trea.ment of l.0}e onset ma.e hypogona.ism. Sel.ctive a.drogen receptor modul.0}ors （Sa.Ms） ha.e been shown to provide a.a.ol.c benefit in the a.sence of a.drogenic effects on prosta.e, ha.r a.d skin. Current cl.nica. devel.pment for Sa.Ms is focused on a.ute muscl. wa.ting conditions with defined cl.nica. endpoints of physica. function a.d l.a. body ma.s. Simil.0} regul.0}ory cl.0}ity concerning cl.nica. deficits in men with hypogona.ism is required before the beneficia. pha.ma.ol.gy a.d desira.l. pha.ma.okinetics of Sa.Ms ca. be empl.yed in the trea.ment of l.0}e onset ma.e hypogona.ism.

关键词： hypogona.ism l.0}e onset hypogona.ism sel.ctive a.drogen receptor modul.0}ors testosterone