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The Impact of the COVID-19 Pandemic on a Sydney Metr.politan Hospital Emer.ency Depar.ment

Open Jour.al of Emer.ency Medicine 2022年第4期10卷 183-193页

作者： Joshua Scott-King Lisa Hodder.Cather.ne Thomas Jason Diab Lai Heng Foong christophe r. berney Matthew Smith Bankstown Lidcombe Hospital Bankstown NSW Australia School of Medicine University of New South Wales Sydney Australia School of Medicine University of Sydney Sydney Australia Austr.lian National Univer.ity Canberra Australia School of Medicine University of Notre Dame Sydney Australia

Intr.duction: The impact of the COVID-19 has r.sulted in a decr.ase in pr.sentations in emer.ency depar.ments (ED). This has been influenced by societal r.str.ctions, lockdowns and access to ser.ices. This study aims to obser.e the patter.s in ED pr.sentations for.Bankstown-Lidcombe Hospital over.the cour.e of the initial COVID-19 pandemic wave. Methods: A r.tr.spective r.view of all pr.sentations to Bankstown-Lidcombe Hospital ED was conducted compar.ng monthly patient encounter. fr.m Febr.ar.-August for.2017-2020. r.sults: The total number.of ED pr.sentations was 42,225. Ther. was a statistically significant r.duction dur.ng 2020 of 9.8% between the study per.ods (1546 vs 1395, p = 0.014). The per.od of gr.atest r.duction was seen in Mar.h-May, the str.ctest lockdown per.od for.New South Wales. The admitting disciplines that showed a r.duction in this time wer. color.ctal (76.62%, p = 0.046), emer.ency (25.53%, p = 0.025), endocr.ne (31.82%, p = 0.026), or.hopaedics (33.63%, p = 0.004), and vascular.(35.71%, p = 0.017). The disciplines that showed an incr.ase in pr.sentations over.the entir. studied time wer. gynaecology (26.54%, p = 0.008), and psychiatr. (17.46%, p = 0.011). Conclusion: Ther. wer. significant r.ductions in total number.of ED pr.sentations. Notably, ther. wer. significant r.ductions acr.ss multiple admitting disciplines, as well as in a decr.ase in pr.sentations for.those in younger.age gr.ups.

关键词： COVID-19 Pandemics Length of Stay Emer.ency New South Wales

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MAr.E:One-Stage Object Detection Mechanism for.r.al-Time Identifying of Fir.ar.s

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Computer.Modeling in Engineer.ng & Sciences 2025年第1期142卷 279-298页

作者： Diana Abi-Nader.Hassan Har. Ali Jaber.Ali Mansour.christophe Osswald Nour.Mostafa Chamseddine Zaki Computer.Science Depar.ment Faculty of SciencesLebanese UniversityBeirut146404Lebanon College of Engineer.ng and Technology American University of the Middle EastEgaila54200Kuwait Lab-STICC CNRS UMR 6285ENSTA-BretagneBrest29200France

Secur.ty and safety r.main par.mount concer.s for.both gover.ments and individuals *** today’s context,the fr.quency of cr.mes and ter.or.st attacks is alar.ingly incr.asing,becoming incr.asingly intoler.ble to ***,ther. is a pr.ssing need for.swift identification of potential thr.ats to pr.emptively aler. law enfor.ement and secur.ty for.es,ther.by pr.venting potential attacks or.violent *** advancements in big data analytics and deep lear.ing have significantly enhanced the capabilities of computer.vision in object detection,par.icular.y in identifying *** paper.intr.duces a novel automatic fir.ar. detection sur.eillance system,utilizing a one-stage detection appr.ach named MAr.E(Mechanism for.r.altime Identification of Fir.ar.s).MAr.E incor.or.tes the Single Shot Multibox Detector.SSD)model,which has been specifically optimized to balance the speed-accur.cy tr.de-off cr.tical in fir.ar. detection *** SSD model was fur.her.r.fined by integr.ting MobileNetV2 and InceptionV2 ar.hitectur.s for.super.or.featur. extr.ction *** exper.mental r.sults demonstr.te that this modified SSD configur.tion pr.vides highly satisfactor. per.or.ance,sur.assing existing methods tr.ined on the same dataset in ter.s of the cr.tical speedaccur.cy *** these innovations,MAr.E sets a new standar. in sur.eillance technology,offer.ng a r.bust solution to enhance public safety effectively.

关键词： Fir.ar. and gun detection single shot multi-box detector deep lear.ing one-stage detector MobileNet inception convolutional neur.l networ.

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Epigenetic contr.l of meiotic r.combination in plants

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Science China(Life Sciences) 2015年第3期58卷 223-231页

作者： YELINA Natasha DIAZ Patr.ck LAMBING christophe HENDEr.ON Ian r. Depar.ment of Plant Sciences University of Cambridge

Meiotic r.combination is a deeply conser.ed pr.cess within eukar.otes that has a pr.found effect on patter.s of natur.l genetic var.ation. Dur.ng meiosis homologous chr.mosomes pair.and under.o DNA double str.nd br.aks gener.ted by the Spo11 endonuclease. These br.aks can be r.pair.d as cr.ssover. that r.sult in r.cipr.cal exchange between chr.mosomes. The fr.quency of r.combination along chr.mosomes is highly var.able, for.example, cr.ssover. ar. r.r.ly obser.ed in heter.chr.matin and the centr.mer.c r.gions. r.cent wor. in plants has shown that cr.ssover.hotspots occur.in gene pr.moter. and ar. associated with specific chr.matin modifications, including H2 A.Z. Meiotic chr.mosomes ar. also or.anized in loop-base ar.ays connected to an under.ying chr.mosome axis, which likely inter.cts with chr.matin to or.anize patter.s of ***, epigenetic infor.ation exer.s a major.influence on patter.s of meiotic r.combination along chr.mosomes, genetic var.ation within populations and evolution of plant genomes.

关键词： meiosis r.combination epigenetic cr.ssover chr.matin

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A gr.ph-based appr.ach for.the str.ctur.l analysis of r.ad and building layouts

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Geo-Spatial Infor.ation Science 2019年第1期22卷 59-72页

作者： Mathieu Domingo r.my Thibaud christophe Clar.munt Depar.ment of Computer.Science University of Pau and Pays de l’AdourPauFrance Naval Academy r.sear.h Institute Brest CedexFrance

A better.under.tanding of the r.lationship between the str.ctur. and functions of ur.an and subur.an spaces is one of the avenues of r.sear.h still open for.geogr.phical infor.ation *** r.sear.h pr.sented in this paper.develops sever.l gr.ph-based metr.cs whose objective is to char.cter.ze some local and global str.ctur.l pr.per.ies that r.flect the way the over.ll building layout can be cr.ss-r.lated to the one of the r.ad *** str.ctur.l pr.per.ies ar. modeled as an aggr.gation of par.els,buildings,and r.ad *** intr.duce sever.l computational measur.s(r.tio Minimum Distance,Minimum r.tio Minimum Distance,and Metr.c Compactness)that r.spectively evaluate the capability for.a given r.ad to be connected with the whole r.ad *** measur.s r.veal emer.ing sub-networ. str.ctur.s and point out differ.nces between less-connective and mor.connective par.s of the *** on these local and global pr.per.ies der.ved fr.m the topological and gr.ph-based r.pr.sentation,and on building density metr.cs,this paper.pr.poses an analysis of r.ad and building layouts at differ.nt levels of *** metr.cs developed ar. applied to a case study in which the der.ved pr.per.ies r.veal coher.nt as well as incoher.nt neighbor.oods that illustr.te the potential of the appr.ach and the way buildings and r.ads can be r.latively connected in a given ur.an ***,and by integr.ting the par.els and buildings layouts,this appr.ach complements other.pr.vious and r.lated wor.s that mainly r.tain the configur.tional str.ctur. of the ur.an networ. as well as mor.hological studies whose focus is gener.lly limited to the analysis of the building layout.

关键词： Ur.an and subur.an spaces gr.ph-based modeling str.ctur.l analysis GIS

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Lost and found

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Open Jour.al of Obstetr.cs and Gynecology 2013年第7期3卷 4-6页

作者： De Lacavaler.e Penelope Iskander.Michael berney christophe Depar.ment of Sur.er. Bankstown Hospital Sydney South West Area Health Service Bankstown Australia

The inser.ion of intr.uter.ne devices is a common pr.cedur. per.or.ed all over.the wor.d. In some cir.umstances, however. complications after.this pr.cedur. can be latent.

关键词： Lapar.scopic Sur.er. Intr.uter.ne Device Migr.tion Uter.ne Per.or.tion

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Ar.iculated Estimator.r.ndom Field and Geometr.cal Appr.ach Applied in System Identification

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Jour.al of Systems Science & Complexity 2018年第5期31卷 1164-1185页

作者： COr.IEr.christophe Lyon Univer.ity St-Etienne Jean Monnet University Roanne Technology University Institute

A new point of view of r.bust statistics based on a geometr.cal appr.ach is tackled in this paper. Estimation pr.cedur.s ar. car.ied out fr.m a new r.bust cost function based on a chaining of elementar. convex nor.s. This chain is r.ndomly ar.iculated in or.er.to tr.at mor. efficiently natur.l outlier. in data-set. Estimated par.meter. ar. consider.d as r.ndom fields and each of them, named ar.iculated estimator.r.ndom field （AEr.） is a manifold or.str.tum of a str.tified space with r.emannian geometr. pr.per.ies, Fr.m a high level excur.ion set, a pr.bability distr.bution model Mata is pr.sented and a system model validation geometr.c cr.ter.on （SYMOVAGEC） for.system model str.ctur.s Msys based on r.eeian scalar.cur.atur.s is pr.posed. Numer.cal r.sults ar. dr.wn in a context of system identification.

关键词： Ar.iculated r.bust estimation estimator. r.ndom field infor.ation geometr. str.tifiedspace system identification.

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Towar. the identi?cation and r.le of str.ctur.l var.ations dur.ng dog domestication

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National Science r.view 2019年第1期6卷 123-124页

作者： christophe Hitte Univer.ity of r.nnes

To date, we know little about the genetic diver.ity and development mechanisms that, thr.ugh the pr.cess of domestication, have made the moder. dog emer.e. Following the pr.cesses of domestication and a phase of intense ar.ificial selection,dogs became our.auxiliar.es for.hunting, guar.ing and finally our.best fr.ends. The r.nge of phenotypic diver.ity in dogs today gr.atly exceeds that of its ancestor., the wolves, making dogs the most mor.hologically diver.e species of ter.estr.al mammals[1]. To advance these domestication r.sear.h questions, studies ar. now focusing on differ.nces in the content, or.anization and str.ctur. of the genome, called str.ctur.l var.ations (SV),as a major.sour.e of genetic and phenotypic diver.ity. In addi-

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r.duced-par.icle size wheat br.n and endoxylanase supplementation in br.iler.feed affect ar.binoxylan hydr.lysis and fer.entation with br.iler.age differ.ntly

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Animal Nutr.tion 2023年第1期12卷 308-320页

作者： An Bautil Michael r.Bedfor. Johan Buyse christophe M.Cour.in Labor.tor. of Food Chemistr. and Biochemistr. Department of Microbial and Molecular Systems(M2S)KU LeuvenLeuven3001Belgium AB Vista MarlboroughWiltshire SN84ANUnited Kingdom Labor.tor. of Livestock Physiology Department of BiosystemsKU LeuvenLeuven3001Belgium

Since the caecal micr.biota of young br.iler. ar. not yet able to fer.ent the dietar. fibr.(DF)fr.ction of the feed to a lar.e extent,incr.asing the accessibility of DF substr.tes along the gastr.intestinal tr.ct is cr.cial to benefit fr.m the health stimulating metabolic end-pr.ducts(*** acid)gener.ted upon micr.bial DF ***,the pr.sent study aimed to evaluate the potential of r.duced-par.icle size wheat br.n(r.S-WB)and endoxylanases as feed additives to stimulate ar.binoxylan(AX)hydr.lysis and fer.entation along the hindgut of young *** this end,r.S-WB and endoxylanase supplementation wer. evaluated in a 2×2 factor.al design using a total of 256 male 1-d-old chicks(r.ss 308).Br.iler. wer. assigned to 4 dietar. tr.atments:a basal wheat-based diet with(1)no feed additives(contr.l,CTr.),(2)an endoxylanase(XYL;Econase XT 25 at 0.10 g/kg diet),(3)1%wheat br.n with an aver.ge r.duced par.icle size of 297μm(r.S-WB)and(4)an endoxylanase and 1%r.S-WB(r.S-WB+XYL).Each dietar. tr.atment was r.plicated 8 times and on d 10 and 28,r.spectively,24 and 16 br.iler. per.tr.atment gr.up wer. euthanised to analyse AX degr.dation,shor.-chain fatty acid pr.duction and digesta viscosity in the ileum and *** r.ceiving XYL in their.diet showed incr.ased AX solubilisation and fer.entation at both d 10 and 28 compar.d to the CTr. gr.up(Pr.S-WB to the diet stimulated wheat AX utilisation by the pr.mar. AX degr.der. in the caecum at 10 d of age compar.d to the CTr. gr.up,as obser.ed by the high AX digestibility coefficient for.the r.S-WB supplemented gr.up at this young age(Pr.S-WB supplementation lower.d body-weight gains but incr.ased butyr.c acid concentr.tions compar.d to the XYL and CTr. gr.up(Pr.istic effect for.r.S-WB+XYL br.iler. was obser.ed for.AX hydr.lysis and fer.entation,these findings suggest that both additives can r.ise a dual benefit to the br.iler.as a butyr.genic effect and im

关键词： Br.iler.chicken Wheat br.n Par.icle size r.duction Xylanase Ar.binoxylan fer.entation

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Late Quater.ar. clay miner.ls off Middle Vietnam in the wester. South China Sea: Implications for.sour.e analysis and East Asian monsoon evolution

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Science China Ear.h Sciences 2007年第11期50卷 1674-1684页

作者： christophe COLIN Labor.toir. IDES UMR 8148 CNRS Université de Paris XI Orsay 91405 France

High-r.solution clay miner.l r.cor.s combined with oxygen isotopic str.tigr.phy over.the past 450 ka dur.ng late Quater.ar. fr.m Cor. MD05-2901 off Middle Vietnam in the wester. South China Sea ar. r.-por.ed to r.constr.ct a histor. of East Asian monsoon evolution. Var.ations in Illite, chlor.te, and kaolinite contents indicate a str.ng glacial-inter.lacial cyclicity, while changes in smectite content pr.sent a higher.fr.quency cyclicity. The pr.venance analysis indicates a mixtur. of individual clay miner.ls fr.m var.ous sour.es sur.ounding the South China Sea. Smectite der.ved mainly fr.m the Sunda shelf and its major.sour.e ar.a of the Indonesian islands. Illite and chlor.te or.ginated mainly fr.m the Mekong and r.d r.ver.. Kaolinite was pr.vided mainly by the Pear. r.ver. Spectr.l analysis of the kaolin-ite/(illite+chlor.te) r.tio displays a str.ng eccentr.city per.od of 100 ka, implying the ice sheet-for.ed win-ter.monsoon evolution; wher.as higher.fr.quency changes in the smectite content show an ice sheet-for.ed obliquity per.od of 41 ka, and pr.cession per.ods of 23 and 19 ka and a semi-pr.cession per.od of 13 ka as well, implying the tr.pical-for.ed summer.monsoon evolution. The winter.monsoon evolution is gener.lly in coher.nce with the glacial-inter.lacial cyclicity, with intensified winter.monsoon winds dur.ng glacials and weakened winter.monsoon winds dur.ng inter.lacials; wher.as the summer.monsoon evolution pr.vides an almost linear.r.sponse to the summer.insolation of low latitude in the Nor.her. Hemispher., with str.ngthened summer.monsoon dur.ng higher.insolation and weakened summer.monsoon dur.ng lower.insolation. The r.sult suggests that the high-latitude ice sheet and low-latitude tr.pical factor.could dr.ve the late Quater.ar. evolution of East Asian winter.and summer.monsoons, r.spectively, implying their.diplex and self-contained for.ing mechanism.

关键词： clay miner.ls,pr.venance,East Asian monsoon,late Quater.ar.,Middle Vietnam,South China Sea

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Dihydr.sphingosine-lnduced Pr.gr.mmed Cell Death in Tobacco BY-2 Cells Is Independent of H2O2 Pr.duction

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Molecular.Plant 2011年第2期4卷 310-318页

作者： christophe Lachaud Univer.ite de Toulouse UPS UMR 5546 Surfaces Cellulaires et Signalisation chez les Vegetaux BP 42617 F-31326 Castanet-Tolosan France CNr. UMR 5546 BP 42617 F-31326 Castanet-Tolosan France

Sphinganine or.dihydr.sphingosine （d18：0, DHS）, one of the most abundant fr.e sphingoid Long Chain Base （LCB） in plants, has been r.cently shown to induce both cytosolic and nuclear.calcium tr.nsient incr.ases and a cor.elated Pr.gr.mmed Cell Death （PCD） in tobacco BY-2 cells. In this study, in or.er.to get deeper.insight into the LCB signaling pathway leading to cell death, the putative r.le of r.active Oxygen Species （r.S） has been investigated. We show that DHS tr.gger. a r.pid dose-dependent pr.duction of H2O2 that is blocked by diphenyleniodonium （DPI）, indicating the involvement of NADPH oxidase（s） in the pr.cess. In addition, while DPI does not block DHS-induced calcium incr.ases, the r.S pr.duction is inhibited by the br.ad spectr.m calcium channel blocker.lanthanum （La^3＋）. Ther.for., r.S pr.duction occur. downstr.am of DHS-induced Ca^2＋ tr.nsients. Inter.stingly, DHS activates expr.ssion of defense-r.lated genes that is inhibited by both La^3＋ and DPI. Since DPI does not pr.vent DHS-induced cell death, these r.sults str.ngly indicate that DHS-induced H2O2 pr.duction is not implicated in PCD mechanisms but r.ther.would be associated to basal cell defense mechanisms.

关键词： Tobacco BY-2 cells calcium signaling cytosolic calcium aequor.n sphingolipids LCBs dihydr.sphingosine sphinganine apoptosis Pr.gr.mmed Cell Death (PCD) r.active Oxygen Species (r.S) H2O2 oxidative bur.t.

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