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Towards trustworthy multi-modal motion prediction:Holistic evaluation and interpretability of outputs

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CAAI Transactions on Intelligence Technology 2024年第3期9卷 557-572页

作者： Sandra Carrasco Limeros Sylwia majchrowska Joakim Johnander christoffer Petersson miguelÁngel Sotelo David Fernández Llorca Computer Engineering Department Polytechnic SchoolUniversity of AlcalaMadridSpain AI Sweden GothenburgSweden Zenseact AB GothenburgSweden Department of Electrical Engineering Linköping UniversityLinköpingSweden Chalmers University of Technology GothenburgSweden European Commission Joint Research CentreSevilleSpain

Predicting the motion of other road agents enables autonomous vehicles to perform safe and efficient path *** task is very complex,as the behaviour of road agents depends on many factors and the number of possible future trajectories can be consid-erable(multi-modal).most prior approaches proposed to address multi-modal motion prediction are based on complex machine learning systems that have limited ***,the metrics used in current benchmarks do not evaluate all aspects of the problem,such as the diversity and admissibility of the *** authors aim to advance towards the design of trustworthy motion prediction systems,based on some of the re-quirements for the design of Trustworthy Artificial *** focus is on evaluation criteria,robustness,and interpretability of ***,the evaluation metrics are comprehensively analysed,the main gaps of current benchmarks are identified,and a new holistic evaluation framework is ***,a method for the assessment of spatial and temporal robustness is introduced by simulating noise in the perception *** enhance the interpretability of the outputs and generate more balanced results in the proposed evaluation framework,an intent prediction layer that can be attached to multi-modal motion prediction models is *** effectiveness of this approach is assessed through a survey that explores different elements in the visualisation of the multi-modal trajectories and *** proposed approach and findings make a significant contribution to the development of trustworthy motion prediction systems for autono-mous vehicles,advancing the field towards greater safety and reliability.

关键词： autonomous vehicles evaluation interpretability multi-modal motion prediction robustness trustworthy AI

The sustainability of valuable metals—recycling of residues from stainless steel production

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Baosteel Technical Research 2010年第S1期4卷 136-页

作者： Kristina BESKOW Andreas RUH christoffer lundstrm Uan Hagfors Teknologi AB Djursholmsvgen 30 SE-18352 TbySweden Befesa Steel Services GmbH Albert-Hahn-Str.9 47269 DuisburgGermany

The European stainless steel producers generate 20 -30 kg dust per ton of produced stainless *** dust formed during various stages of the production process contains valuable metals such as Cr,Ni and *** general this dust is considered as a hazardous *** not taken care of the dust will be an environmental risk causing potential problems such as leaching of heavy metals into groundwater and pollution of land and *** applying techniques for recycling the dust the problem is minimized and valuable metals are recovered and re-used as raw material in the steel making process,leading to a significant reduction of the consumption of natural resources to decelerate the climate change and ensure a sustainable *** of the business segments of Befesa Zinc S.L.U.,a subsidiary company of Abengoa,is the recycling of dusts and other residues containing nickel,chromium and molybdenum from the stainless steel *** technologies applied are submerged arc reduction smelting(Befesa Valera S.A.S.,Gravelines,France) and plasma reduction smelting(Befesa ScanDust AB,Landskrona,Sweden).Stainless steel plant dusts,mill scale and other residues are delivered in closed containers and big bags by ship,rail or truck and *** a preparation of the residues and charging into the pyrometallurgical furnace,the metal compounds contained in the charge are reduced to metals in the presence of the carbon *** Befesa ScanDust,the regularly tapped liquid metal is cast in the form of granules via the Granshot^(?) granulation *** granulated product has many advantages such as excellent preheating properties and fast melting when added to a metallurgical *** granules size and shape also makes it very suitable to handle with most raw material handling *** granulating the so-called alloyed pig iron(API) a high metallic yield is achieved ensuring maximum recovery of metal and less new dust generation compared to a crushed *** granules

关键词： recycling stainless steel dust Befesa Granshot metal granulation sustainable development

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一抹绿色挪威Lumber4商业办公楼

室内设计与装修 2024年第1期 90-93页

作者： [挪威]Oslotre architects 麦子(编译) Kyrre Sundal(摄影) christoffer Imislund(摄影) Oslotre architects

Lumber4是一栋6层的商业办公楼。内退的首层为商业空间,上面5层则为办公空间。该大楼由木结构组成,其立柱和横梁均采用胶合层压木。室内楼板采用CLT和混凝土的复合结构,形成了一个高效的系统,可满足大跨度空间需求,同时符合消防及声学... 详细信息

Lumber4是一栋6层的商业办公楼。内退的首层为商业空间,上面5层则为办公空间。该大楼由木结构组成,其立柱和横梁均采用胶合层压木。室内楼板采用CLT和混凝土的复合结构,形成了一个高效的系统,可满足大跨度空间需求,同时符合消防及声学要求。一层的对角线结构便于车辆通行,而大楼内部的交通核心则有利于建筑横向的稳定性和内部楼层间的连接。

关键词：办公空间商业空间商业办公楼声学要求木结构大跨度空间复合结构消防

Trajectories of response in schizophrenia-spectrum disorders: A one-year prospective cohort study of antipsychotic effectiveness

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World Journal of Psychiatry 2022年第3期12卷 521-532页

作者： Petros Drosos Erik Johnsen christoffer Andreas Bartz-Johannessen Tor Ketil Larsen Solveig Klæbo Reitan maria Rettenbacher Rune Andreas Kroken TIPS-Network for Clinical Research in Psychosis Clinic For Adult Mental HealthStavanger University HospitalStavanger 4011Norway NORmENT Division of PsychiatryHaukeland University HospitalBergen 5036Norway Department of Clinical medicine University of BergenBergen 5007Norway Institute for mental Health St Olav's University HospitalTrondheim 7030Norwa Department of mental Health Norwegian University of Natural Science and TechnologyTrondheim 7491Norway Department of Psychiatry and Psychotherapy Medical University InnsbruckInnsbruck 6020Austria

BACKGROUND Antipsychotic drugs remain the mainstay of schizophrenia treatment;however,their effectiveness has been questioned,and it is not possible to predict the response to a specific antipsychotic drug in an individual ***,it is important to compare the effectiveness of the various antipsychotics and search for possible response *** To investigate the effectiveness of antipsychotic drugs,we examined response trajectories and predictors for belonging to different trajectory *** The Bergen-Stavanger-Innsbruck-Trondheim(BeSt InTro)trial compared the effectiveness of three atypical antipsychotics-amisulpride,aripiprazole,and olanzapine-in a prospective,semirandomized,rater-blind,head-to-head *** participants with a schizophrenia spectrum disorder diagnosis,according to international classification of diseases,Tenth Revision(ICD-10)F20–29,were *** were followed for a period of 12 mo,with assessments at baseline;after one,three and six weeks;and after three,six,nine and 12 mo.A latent class mixed model was fitted to our *** three-trajectory model based on the Positive and Negative Syndrome Scale(PANSS)total score reduction was found to have adequate fit,and the study drugs,as well as various demographic and clinical parameters,were tested as predictors for belonging to the different trajectory *** Overall,144 participants were included,and 41%completed the 12-mo study *** largest trajectory group,consisting of 74%of participants,showed a PANSS total score reduction of 59%from baseline to 12 mo(Good response group).A trajectory group comprising 13%of participants had their PANSS total score reduced by 82.5%at 12 mo(Strong response group),while the last response trajectory group comprising 13%of the participants had a PANSS total score reduction of 13.6%(Slight response group).The largest part of the total reduction for the Good and Strong response groups occurred at six weeks of treatment,

关键词： Schizophrenia Response Trajectories Treatment Antipsychotic drugs

Hemoglobin expression in rat experimental granulation tissue

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分子细胞生物学报:英文版 2011年第3期3卷 190-196页

作者： miretta Tommila christoffer Stark Anne Jokilammi Ville Peltonen Risto Penttinen Erika Ekholm Department of medical Biochemistry and Genetics University of TurkuTurkuFinland Department of Anesthesiology Intensive CareEmergency and Pain MedicineTurku University HospitalTurkuFinland

The general opinion that hemoglobin is only a carrier protein for oxygen and carbon dioxide has been challenged by several recent studies showing hemoglobin expression in other cells than those of the erythroid series,for example,in *** discovered b-globin expression in rat experimental granulation tissue induced by subcutaneously implanted cellulose *** investigation revealed also a-globin *** first peak of the biphasic globin expression noticed during granulation tissue formation correlated with the invasion of monocytes/macrophages,whereas the second one seemed to be connected to the appearance of hematopoietic *** presented in this study indicate globin expression both in macrophages and in immature erythroid cells as validated by erythroid-specific markers.

关键词： granulation tissue wound healing hemoglobin expression extramedullary hematopoiesis rat

Inflammatory pathways of importance for management of inflammatory bowel disease

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World Journal of Gastroenterology 2014年第1期20卷 64-77页

作者： Jannie Pedersen mehmet Coskun christoffer Soendergaard mohammad Salem Ole Haagen Nielsen Department of Gastroenterology Medical SectionUniversity of CopenhagenHerlev HospitalDK-2730 HerlevDenmark Department of Cellular and molecular medicine the Panum InstituteUniversity of CopenhagenDK-2200 CopenhagenDenmark

Inflammatory bowel disease(IBD)is a group of chronic disorders of the gastrointestinal tract comprising Crohn’s disease(CD)and ulcerative colitis(UC).Their etiologies are unknown,but they are characterised by an imbalanced production of pro-inflammatory mediators,e.g.,tumor necrosis factor(TNF)-α,as well as increased recruitment of leukocytes to the site of *** in understanding the role of the inflammatory pathways in IBD and an inadequate response to conventional therapy in a large portion of patients,has over the last two decades lead to new therapies which includes the TNF inhibitors(TNFi),designed to target and neutralise the effect of TNF-α.TNFi have shown to be efficient in treating moderate to severe CD and ***,convenient alternative therapeutics targeting other immune pathways are needed for patients with IBD refractory to conventional therapy including ***,several therapeutics are currently under development,and have shown success in clinical *** include antibodies targeting and neutralising interleukin-12/23,small pharmacologic Janus kinase inhibitors designed to block intracellular signaling of several pro-inflammatory cytokines,antibodies targeting integrins,and small anti-adhesion molecules that block adhesion between leukocytes and the intestinal vascular endothelium,reducing their infiltration into the inflamed *** this review we have elucidated the major signaling pathways of clinical importance for IBD therapy and highlighted the new promising therapies *** stated in this paper several new treatment options are under development for the treatment of CD and UC,however,no drug fits all ***,optimisations of treatment regimens are warranted for the benefit of the patients either through biomarker establishment or other rationales to maximise the effect of the broad range of mode-of-actions of the present and future drugs in IBD.

关键词： Anti-tumor necrosis factor Biologics Crohn’s disea

A sensitivity study of the WRF model in offshore wind modeling over the Baltic Sea

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Geoscience Frontiers 2021年第6期12卷 209-222页

作者： Huidong Li Björn Claremar Lichuan Wu christoffer Hallgren Heiner Körnich Stefan Ivanell Erik Sahlée Department of Earth Sciences Uppsala UniversityUppsala 75236Sweden Swedish meteorological and Hydrological Institute Norrköping 60176Sweden

Accurate wind modeling is important for wind resources assessment and wind power forecasting. To improve the WRF model configuration for the offshore wind modeling over the Baltic Sea, this study performed a sensitivity study of the WRF model to multiple model configurations, including domain setup,grid resolution, sea surface temperature, land surface data, and atmosphere-wave coupling. The simulated offshore wind was evaluated against LiDAR observations under different wind directions, atmospheric stabilities, and sea status. Generally, the simulated wind profiles matched observations, despite systematic underestimations. Strengthening the forcing from the reanalysis data through reducing the number of nested domains played the largest role in improving wind modeling. Atmosphere-wave coupling further improved the simulated wind, especially under the growing and mature sea *** the vertical resolution, and updating the sea surface temperature and the land surface information only had a slight impact, mainly visible during very stable conditions. Increasing the horizontal resolution also only had a slight impact, most visible during unstable conditions. Our study can help to improve the wind resources assessment and wind power forecasting over the Baltic Sea.

关键词： Offshore wind modeling Sensitivity study Atmosphere-wave coupling WRF Baltic Sea

The margins of European Identity Orthodox Geopolitics in moldovan Ethnopolitics

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Cultural and Religious Studies 2015年第2期3卷 118-123页

作者： christoffer Stoerup University of Copenhagen Copenhagen Denmark

This article presents the preliminary results of an ongoing Ph. D. project examining the interrelatedness of competing religious, nationalist and geopolitical projects in the Republic of moldova. By looking at the local churches" public address around key events in recent moldovan history, it is sought to determine to which degree the local churches are mirroring the positions of the patriarchates and their hosting states. The main hypothesis is that the local churches to a larger extent than recognized in the existing literature are acting independently pursuing their local interests and forming alliances to this end. If this is the case the churches can be expected to phrase the question of national and geopolitical belonging differently from the competing moldovanist and pan-Romanian narratives as well as the European and Eurasian projects.

关键词：文化理论哲学宗教

Antibiotics Resistance Profile of Bacillus cereus Strains Isolated from Soil and Pepper in Brazzaville

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Journal of Biosciences and medicines 2022年第9期10卷 30-40页

作者： Isaac Samuel Onyankouang Nicole Prisca makaya Dangui Nieko Cyr Jonas morabandza moїse Doria Kaya-Ongoto christoffer Pregna mounkala Etienne Nguimbi Faculté des Sciences et Techniques Université Marien Ngouabi Brazzaville Congo Laboratoire National de Santé Publique Brazzaville Congo Laboratoire de microbiologie Infectiologie et Immunologie Ecole Normale Supérieure Université Marien Ngouabi Brazzaville Congo

Introduction: Bacillus cereus and spores produced in various ecological niches are responsible for toxic infections in humans. This study is conducted to determine the antibiotics resistance profile of B. cereus strains isolated from soil and pepper consummated in Brazzaville. methodology: An antimicrobial susceptibility test of 16 B. cereus strains from soil and peppers was performed using 11 antibiotics by the Kirby-Bauer’s diffusion on disc method. Results: Results revealed 100% (16/16) of resistance in penicillin G, amoxicillin, ceftazidime, rifampicin, and colistin, also 18.75% (3/16), 11.76% (2/16), and 18.75% (3/16) of resistance in doripenem, vancomycin and chloramphenicol respectively. In addition, we have observed 100% (16/16), 81.25% (13/16), 76.47% (13/16), 35.29% (5/16), 35.50% (6/16), and 12.5% (2/16) of sensitivity to line-zolid, tigecycline, ciprofloxacin, vancomycin, doripenem and chloram-phenicol respectively. However, all strains have been multidrug resistant (mDR) to betalactams, polypeptides, and ansamycins. moreover, 7 strains (43.75%) have been variably multiresistant. One strain, Ri10 has been resistant to beta-lactams, polypeptides, ansamycins, cyclins and glycopeptides. No strain was ultraresistant (XDR) or largely insensitive (PDR) to different antibiotics. Conclusion: This study reveals that 51% of strains have been resistant to antibiotics, 32% are sensitive, and 17% have intermediate resistance. These results partly explain the high rate of gastroenteritis observed in Brazzaville due to food poisoning.

关键词： Antibiotics Resistance Bacillus cereus Soil Pepper