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Anticaries and antimicrobial activities of methanolic extract from leaves of Cleistocalyx operculatus L.

Asian Pacific Journal of Tropical Biomedicine 2017年第1期7卷 43-48页

作者： Phuong Thi Mai Nguyen Nadin Schultze christin Boger Zeyad Alresley Albert Bolhuis Ulrike Lindequist Department of Plant Biochemistry Institute of BiotechnologyVietnam Academy of Science and Technology Institute of Pharmacy University of Greifswald Department of Pharmacy and Pharmacology University of Bath

Objective: To investigate antimicrobial activities of methanolic extract of leaves of Cleistocalyx operculatus L.(C. operculatus) grown in ***: The methanolic extract of C. operculatus leaves was phytochemically screened and tested for its antimicrobial activity against six Gram-positive bacteria(three of which were antibiotic multiresistant Staphylococcus spp.), two Gram-negative bacteria,and one fungal species using an agar diffusion method. Anticaries activity was tested using p H drop and biofilm assays formed in 96-well plastic ***: Phytochemical screening revealed the presence of flavonoids and terpenes, in which flavonoid content was 6.8 mg/g dry material. Antibacterial activity of the C. operculatus extract was shown only against Gram-positive bacteria Staphylococcus aureus, Bacillus subtilis and Streptococcus mutans GS-5(S. mutans), and three multiresistant bacteria being Staphylococcus epidermidis 847, Staphylococcus haemolyticus 535 and Staphylococcus aureus North German epidemic strain. Interestingly, methanolic extract of C. operculatus leaves exhibited the anticaries activity against S. mutans in terms of inhibition of acid production and biofilm formation. Activity of two key enzymes responsible for acidogenicity of S. mutans, F-ATPase and phosphotransferase system were inhibited by the extract with IC_(50) of 51.0 and 98.0 m g/m L, respectively. Cytotoxicity of the extract against keratinocytes was found only for higher concentrations [IC_(50)=(119.98 ± 4.63) m g/m L].Conclusions: The methanolic extract of C. operculatus leaves has the potential for development of antimicrobial preparations, especially anticaries products.

关键词： Cleistocalyx operculatus Antibacterial activity Anticaries Cytotoxicity

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Effect of auditory stress agents on heterozygous German waltzing guinea pigs

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Journal of Otology 2014年第4期9卷 179-190页

作者： sa Skjnsberg Maoli Duan Ann-christin Johnson Mats Ulfendahl Department of Clinical Science Intervention and TechnologyDivision of AudiologyKarolinska Instituter Department of Neurotology and Audiology Karolinska University Hospital Department of Neuroscience Karolinska Institutet

The German waltzing guinea pig is a strain of animals expressing deafness and severe balance disorders at *** mutation arose spontaneously in a breeding facility in Germany and as the affected animals show a characteristic waltzing behavior,the strain is named the German waltzing guinea *** strain is presently bred only at Karolinska *** hereditary inner ear impairment has a recessive mode of inheritance and the strain thus produces not only affected homozygotes but also symptom-free heterozygotes and fully normal *** outcome depends solely on the genotype of the *** heterozygotes,which have obtained the 'waltzing' gene from one parent only,have normal hearing and no balance *** heterozygous animals appear normal but will,in turn,carry the genetic defect to the next *** present thesis is focused on these *** and ototoxic drugs are well known stress factors that interfere negatively with the hearing organ in both humans and animals,causing hearing ***,the inter-individual variability in susceptibility to auditory stress factors is surprisingly large,most likely due to different genetic *** this study,heterozygous animals of the German waltzing guinea pig,animals carrying a genetic defect known to cause severe hearing impairment,were used to study how an unexplored gene for deafness interacts with auditory stress agents,*** exposure and the ototoxic drugs gentamicin and *** were exposed to both narrowband as well as broadband noise at different ages and hearing thresholds were measured using *** of the German waltzing guinea pig showed less threshold shifts compared to control *** animals were less affected by the noise trauma than younger *** test the hypothesis that the efferent system contributes to protection of the inner ear against noise trauma,measurements using a new method of post onset adaptation of DPOAEs a

关键词： Age-dependent hearing loss DPOAE Noise trauma Ototoxic drugs Protection

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District Policy---Social Practice Through Internal and External Discourses： How the Implementation of a Single Regional Political Instrument Is Perceived, Understood and Communicated

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Journal of Sociology Study 2012年第1期2卷 68-82页

作者： Heidi Engesbak christin Tcnseth Norwegian University of Science and Technology （NTNU） Norway

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Mycoremediation of Petroleum： A Literature Review

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Journal of Environmental Science and Engineering(A) 2016年第8期5卷 397-405页

作者： christin Anderson Glenn Juday School of Natural Resources and Extension University of Alaska Alaska 99775 USA

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The nurses’ voice of working in a newly established community based 24-hour support center for people with psychiatric disabilities

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Open Journal of Nursing 2013年第2期3卷 195-201页

作者： Ann-christin Janlov Agneta Berg School of Health and Society Kristianstad UniversityKristianstadSweden

This study explores the perceptions of a small group of nurses working at a newly established 24-hour community-based service enter (SC) for users with psychiatric disability using a qualitative approach. Since the mental health reform in Sweden in 1995 where the communities (in Sweden called municipalities) were given the responsibility to establish service and support to people with severe psychiatric disabilities, they have struggled in finding suitable forms of these kinds of areas. In 2010, this led to the creation and development of a new center aiming to provide services and support based on the expressed needs of people with physchiatric disability in a community located in southern Sweden. During 2011, a total of three group interviews were performed to capture the employed nurses’ perceptions of this newly established SC. The interview texts were analyzed by way of qualitative content analysis. A first reading of the interview texts revealed that the nurses’ perceptions of the service center were unwaveringly positive but that their beliefs about who the specific target group were differed. The main finding was summarized by the theme: Making a difference—on an individual, professional, and organizational level. The sub themes were: 24-hour availability, unclear assignment, and preventing mental illness. The findings indicate a need for a community round-the-clock service center in this Swedish community and a more clear definition of the target group.

关键词： Psychiatric Disability Mental Health Nursing Community Mental Health Service 24-Hour Service Center Qualitative Content Analysis

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Dose-efficient scanning Compton X-ray microscopy

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Light(Science & Applications) 2023年第6期12卷 1141-1152页

作者： Tang Li JLukas Dresselhaus Nikolay Ivanov Mauro Prasciolu Holger Fleckenstein Oleksandr Yefanov Wenhui Zhang David Pennicard Ann-christin Dippel Olof Gutowski Pablo Villanueva-Perez Henry N.Chapman Saša Bajt The Hamburg Centre for Ultrafast Imaging 22761 HamburgGermany Center for Free-Electron Laser Science CFEL Deutsches ElektronenSynchrotron DESY22607 HamburgGermany Deutsches Elektronen Synchrotron DESY 22607 HamburgGermany Synchrotron Radiation Research and NanoLund Lund University22100 LundSweden Department of Physics Universität Hamburg22761 HamburgGermany

The highest resolution of images of soft matter and biological materials is ultimately limited by modification of the structure,induced by the necessarily high energy of short-wavelength *** the inelastically scattered X-rays at a photon energy of 60 keV(0.02 nm wavelength)offers greater signal per energy transferred to the sample than coherent-scattering techniques such as phase-contrast microscopy and projection *** present images of dried,unstained,and unfixed biological objects obtained by scanning Compton X-ray microscopy,at a resolution of about 70 *** microscope was realised using novel wedged multilayer Laue lenses that were fabricated to sub-ångström precision,a new wavefront measurement scheme for hard X rays,and efficient pixel-array *** doses required to form these images were as little as 0.02%of the tolerable dose and 0.05%of that needed for phase-contrast imaging at similar resolution using 17 keV photon *** images obtained provide a quantitative map of the projected mass density in the sample,as confirmed by imaging a silicon *** on these results,we find that it should be possible to obtain radiation damage-free images of biological samples at a resolution below 10 nm.

关键词： wedge dried scattered

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货币政策立场对公司财务构成的影响：印度尼西亚公司级证据

货币政策立场对公司财务构成的影响：印度尼西亚公司级证据

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作者： christin Eunike 上海财经大学

学位级别：硕士

货币政策是中央银行为了通过实施BI利率来实现货币稳定而实施的政策。货币政策立场变化的影响之一是公司外部融资构成的变化,即债务。根据金融加速器机制,货币政策紧缩会对资产负债表产生负面影响,使获得新贷款变得更加困难。因此,本研... 详细信息

货币政策是中央银行为了通过实施BI利率来实现货币稳定而实施的政策。货币政策立场变化的影响之一是公司外部融资构成的变化,即债务。根据金融加速器机制,货币政策紧缩会对资产负债表产生负面影响,使获得新贷款变得更加困难。因此,本研究的目的是通过使用印度尼西亚公司的数据,在给定公司特定特征（规模、抵押品、债务和盈利能力）的情况下,检验在紧缩和宽松货币政策期间资产负债表渠道对公司财务构成的证据。2007年至2016年在IDX上市。该发现为支持通过资产负债表渠道传导货币政策提供了证据。

关键词：货币政策外部融资企业特征资产负债表渠道金融加速器

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Determination of Bonding Failures in Transparent Materials with Non-Destructive Methods—Evaluation of Climatically Stressed Glued and Laminated Glass Compounds

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World Journal of Engineering and Technology 2018年第2期6卷 315-331页

作者： christin Sirtl christin Sirtl Matthias Kraus Matthias Kraus Christiane Hadlich Christiane Hadlich Andrea Osburg Andrea Osburg Department of Steel and Hybrid Structures Bauhaus University of Weimar Weimar Germany Department of Building Chemistry and Polymer Materials Bauhaus University of Weimar Weimar Germany

As part of an international research project—funded by the European Union—capillary glasses for facades are being developed exploiting storage energy by means of fluids flowing through the capillaries. To meet highest visual demands, acrylate adhesives and EVA films are tested as possible bonding materials for the glass setup. Especially non-destructive methods (visual analysis, analysis of birefringent properties and computed tomographic data) are applied to evaluate failure patterns as well as the long-term behavior considering climatic influences. The experimental investigations are presented after different loading periods, providing information of failure developments. In addition, detailed information and scientific findings on the application of computed tomographic analyses are presented.

关键词： Non-Destructive Testing Bonding Methods Computed Tomography

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Analysis of monocyte chemotactic protein-1 gene polymorphism in patients with spontaneous bacterial peritonitis

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World Journal of Gastroenterology 2009年第44期15卷 5558-5562页

作者： Erwin Gbele Marcus Mhlbauer Hartwig Paulo Monika Johann christin Meltzer Franz Leidl Norbert Wodarz Reiner Wiest Jrgen Schlmerich Claus Hellerbrand Department of Internal Medicine University Medical Center RegensburgD-93042 RegensburgGermany Department of Psychiatry University Medical Center RegensburgD-93042 RegensburgGermany

AIM:To investigate a genetic polymorphism of the monocyte chemotactic protein-1 (MCP-1 ) gene in patients with spontaneous bacterial peritonitis (SBP).METHODS:MCP-1 genotyping was performed in 23 patients with SBP and 83 cirrhotic control patients with non-infected ***:The frequency of carriers of the G-allele was lower in SBP patients but this difference did not reach statistical significance. However,in the subgroup of patients with alcoholic cirrhosis (n=80),carriers of the G-allele were significantly less frequent in SBP-patients (38.1%) than in cirrhotic controls (67.8%,P=0.021). CONCLUSION:In patients with alcoholic liver cirrhosis,the-2518 MCP-1 genotype AA is a risk factor for the development of SBP.

关键词：基因多态性单核细胞腹膜炎细菌性患者等位基因收缩压肝硬化

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The lived experience of a 24-hour support center for persons with psychiatric disabilities: Making me feel almost like an ordinary person

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Open Journal of Nursing 2014年第1期4卷 42-50页

作者： Ann-christin Janlov Irene Persson Agneta Berg School of Health and Society Kristianstad UniversityKristianstadSweden Department of Nursing Health and CultureUniversity WestTrollhättanSweden

This study illuminates nine psychiatric disabled persons’ lived experience of a newly established community-based service center open around the clock. This new 24-hour support center (SC) was established in 2011 in a Swedish community to better match and facilitate the disabled persons’ needs. In order to illuminate the disabled person’s experiences individual interview was performed. A phenomenological-hermeneutical method inspired by Paul Ricoeur was used to interpret the texts. After a naive reading, a structural analysis revealed two themes: 1), becoming aware of myself as a person, and 2) having a lifeline and belongingness. The comprehensive understanding was interpreted as meaning “Making me feel almost like an ordinary person”, which incorporated the person’s past with their present together with a direction for the future and hope for a more fulfilling life.

关键词： Psychiatric Disability Lived Experience Community Mental Health Service 24-Hour Service Center Phenomenological-Hermeneutical Method Mental Health Nursing

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