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同步X射线衍射与分子模拟研究AlPO_4-18骨架中N,N-二异丙基乙胺模板分子的位置和取向（英文）

催化学报 2015年第6期36卷 874-879页

作者： christiana zenonos Dewi W.Lewis Gopinathan Sankar Department of Chemistry University College London

Phase pure AlP O4 with the AlP O4-18(AEI) structure was synthesised using N,N- diisopropylethylamine as a template. Using a combination of X-ray powder diffraction and computational methods, the location and orientation of the N,N-diisopropylethylamine molecules inside the cages of the AEI structure were determined. Thermogravimetric analysis confirmed that the number of template molecules per unit cell was consistent with the diffraction study. We unequivocally show that only one template molecule is present in each cage of the crystalline AEI material. Our work demonstrates that a combined approach enables accurate structure resolution of such complex materials.

关键词： X射线粉末衍射模板分子分子模拟二异丙基同步加速器位置取向框架

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Truthfully coordinating participation routes in informative participatory sensing

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Science China(Information Sciences) 2021年第12期64卷 132-146页

作者： Shaofei CHEN Dengji ZHAO Alexandros zenonos Jing CHEN Lincheng SHEN College of Intelligence Science and Technology National University of Defense Technology School of Information Science and Technology ShanghaiTech University School of Electronics and Computer Science University of Southampton

Participatory sensing is a promising approach with which people contribute sensory information to form a body of knowledge. In practice, people may have different ways to engage in a participatory sensing campaign. For example, there are several possible routes from a participant’s home to her office, where a route can be seen as a set of space-temporal coordinates, and measurements can be taken at these coordinates. To coordinate participation routes to collect more valuable information with a limited number of participants,a further concept, informative participatory sensing(IPS) has been developed recently. However, existing IPS systems lack incentive mechanisms to fight against the strategic behaviours of self-interested users.Hence, we propose a formal model of IPS where a service provider can coordinate individual schedules of self-interested participants. As the problem of informative path coordination is NP-hard, the well-known mechanism, Vickrey-Clarke-Groves(VCG) will be computationally inefficient to solve our problem. Given this, we design a sequentially sorting mechanism(SSM) for the model to allocate the schedules and determine the bonuses for these participants, and we then theoretically prove that SSM is computationally efficient,individually rational, profitable and truthful. Furthermore, we empirically evaluate our route allocation method in simulations and show that it significantly outperforms several benchmark approaches.

关键词： coordinating participation routes Coordinating participation routes informative participatory sensing incentive mechanism computationally efficient

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在 colorectal 癌症的地岬发信号小径，变化和他们的角色

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World Journal of Gastrointestinal Oncology 2013年第5期5卷 97-101页

作者： Kypros zenonos Katy Kyprianou College of Medical and Dental Sciences University of Birmingham

Two of the main cellular pathways in which the RAS protein operates are the mitogen-activated protein kinases (MAPK) and phosphoinositide-3 kinase (PI3K) pathways. In a normal cell, these are important in controlling several functions, such as cell growth and survival. It becomes self-evident that these events will be disrupted in a malignant cell with a deregulated MAPK or PI3K pathway. Mutations in genes involved in these pathways and interacting with RAS, as well as RAS itself will be discussed. The second part of this review concentrates on how crucial RAS signaling is in colorectal cancer progression, with references to treatment response and prognosis when RAS or other related mutations are present.

关键词： Genes RAS Colorectal neoplasms Thera-peutics Mitogen-activated protein kinase signaling system

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