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ClC-3基因过表达对小鼠骨量和骨结构的影响

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中国病理生理杂志 2016年第3期32卷 499-503页

作者：汪源邓志钦吕瑞玲王海波高宏梁协稠谭秋婵朱林燕李青南王立伟陈丽新暨南大学医学院生理学系广东广州510632 暨南大学药理学系广东广州510632 广东药学院生命科学与生物制药学院广东广州510006

目的:研究过表达电压门控氯通道家族蛋白成员3(voltage-gated chloride channel family protein 3,ClC-3)基因对小鼠骨骼的影响。方法:3月龄雄性FVB小鼠用鼠尾基因检测法确定基因型后分为2组:野生型(WT)组和ClC-3过表达(ClC-3 transgene... 详细信息

目的:研究过表达电压门控氯通道家族蛋白成员3(voltage-gated chloride channel family protein 3,ClC-3)基因对小鼠骨骼的影响。方法:3月龄雄性FVB小鼠用鼠尾基因检测法确定基因型后分为2组:野生型(WT)组和ClC-3过表达(ClC-3 transgene)组,每组各8只。分别测量2组小鼠体重,右侧胫骨长度和重量。取胫骨上段和中段进行脱钙,石蜡包埋,切片,HE染色后,采用骨形态计量学分析胫骨上段松质骨的骨小梁面积百分数(percent trabecular area,%***)、骨小梁数量(trabecular number,Tb.N)、骨小梁宽度(trabecular width,***)、骨小梁分离度(trabecular separation,***)和胫骨中段皮质骨的骨组织总面积(total tissue area,***)、皮质骨面积(cortical area,***)、皮质骨面积百分数(percent cortical area,%***)、骨髓腔面积(marrow area,***)、骨髓腔面积百分数(percent marrow area,%***)。结果:小鼠经鼠尾基因检测后确认为野生型或ClC-3过表达型。与WT组相比,ClC-3 transgene组小鼠体重及胫骨长度重量均减小(P<0.05);松质骨的%***和***均减小(P<0.05),***增大(P<0.05),Tb.N的变化无统计学意义;皮质骨的***、***和%***均减小(P<0.05),%***增大(P<0.05),***的变化无统计学意义。结论:ClC-3过表达导致小鼠的皮质骨和松质骨骨量减少,骨结构变差,提示ClC-3可能参与了骨形成和/或骨吸收。

关键词：电压门控氯通道家族蛋白成员3 骨形态计量学松质骨皮质骨

Arrayed piezoresistive and inertial measurement unit sensor-integrated assistant training tennis racket for multipoint hand pressure monitoring and representative action recognition

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Science China(Technological Sciences) 2023年第6期66卷 1746-1756页

作者： YANG MingChuan HOU XiaoJuan WU Hui GUO YangYanHao ZHANG Jie xie Xin XIAN Shuai WANG Min ZHANG Le QIAN Shuo HE Jian chou XiuJian Science and Technology on Electronic Test and Measurement Laboratory North University of ChinaTaiyuan 030051China School of Software North University of ChinaTaiyuan 030051China

Technology-assisted ball training systems have become a research hotspot due to their ability to provide quantitative data for guiding athletes to address their areas of ***,traditional tennis training systems still have some limitations;for instance,they are subjective,expensive,heavy,and *** this research,an assistant training tennis racket,which consists of arrayed flexible sensors and an inertial measurement unit,has been proposed to comprehensively analyze the representative actions’force and *** of MXene as the sensitive material and melamine sponge as the substrate(named MMSS),the flexible sensor exhibited an excellent sensitivity of 5.35 kPa^(-1)(1.1-22.2 kPa)due to the formation of a 3D conductive ***,the sensor retained a high sensitivity of 0.6 k Pa-1in an ultrawide measurement range(22.2-266 kPa).In addition to recognizing the type of hitting action,an artificial intelligence algorithm was introduced to accurately differentiate the five typical motion behaviors with an accuracy rate of 98.2%.This study not only proposes a comprehensive assistant training tennis racket for improving the techniques of tennis enthusiasts but also a new information processing scheme for intelligent sensing and distinction of different movements,which can offer significant application potential in sports big data collection and the Internet of things.

关键词： IMU arrayed piezoresistive sensors multipoint monitoring action recognition intelligent sports

New formulae for calculating activities from binary system phase diagrams containing solid solution by introducing the parameterθ

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International Journal of Minerals,Metallurgy and Materials 1997年第3期11卷 1-4页

作者： ZHANG Fan xie Fanyou CAI Wenjuan chou Kuochih (Applied Science School, University of Science and Technology Beijing, Beijing 100083, China)

New formulae for calculating activities and activity coefficients from binary phase diagrams containing solidsolution are presented. In the new formulae, a parameterθ is introduced. It seems be more efficient The app... 详细信息

关键词： phase diagram activity activity coefficient solution θ parameter

Effect of Needle-retaining Time on Therapeutic Efficacy for Post-stroke Hemiplegia

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Journal of Acupuncture and Tuina Science 2013年第4期11卷 222-225页

作者： Li Hai-zhou xie Kai Zhou Li-feng Fu Qing-lan Zheng Pei-hong Han chou-ping Rehabilitative Care Technique Teaching and Research Room Ningbo Tianyi Polytechnic Lianhua Hospital Zhenhai District

Objective： To observe the effect of needle-retaining time in scalp acupuncture on therapeutic efficacy for post-stroke hemiplegia. Methods： A total of 82 cases who met the inclusion criteria were randomly allocated into a control group （22 cases）, a short-time needle- retaining group （30 cases） and a long-time needle-retaining group （30 cases）. Conventional Bobath therapy was employed in the control group while the scalp acupuncture was combined in the short-time （0.5 h） needle-retaining group and long-time （24 h） needle-retaining group. Then functional assessments were made 1 month and 3 months after treatment using FugI-Meyer motor scale {FMMS）, FugI-Meyer assessment of balance （FMA-B） and modified Barthel index （MBI） score. Results： Cases in the long-time needle-retaining group obtained better effects in motor function of the limbs and activities of daily living （ADL） than the other two groups （P〈0.05）. In addition, there was no statistical significance between the short-time needle-retaining group and the control group （P〉0.05）. Conclusion： The needle-retaining time in scalp acupuncture is substantially associated with the effect for post-stroke hemiplegia and long-time needle-retaining is more advisable.

关键词： Acupuncture Therapy Scalp acupuncture Stroke Complications Hemiplegia Rehabilitation

糖化血红蛋白、同型半胱氨酸与中老年急性冠脉综合征患者冠脉病变相关性分析

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广东医科大学学报 2024年第1期42卷 61-64页

作者：欧宇筹李明琰黎锦辉谢宇洲陈梓伟何文凯广州医科大学附属第二医院心血管内科广东广州510000

目的了解糖化血红蛋白(HbA1c)、同型半胱氨酸(Hcy)与急性冠脉综合征(ACS)患者冠脉病变相关性。方法 515例中老年ACS患者根据冠脉造影结果分为单支冠脉病变组和多支冠脉病变组,根据Gensini评分分为轻度和中重度病变组,采用Pearson相关... 详细信息

目的了解糖化血红蛋白(HbA1c)、同型半胱氨酸(Hcy)与急性冠脉综合征(ACS)患者冠脉病变相关性。方法 515例中老年ACS患者根据冠脉造影结果分为单支冠脉病变组和多支冠脉病变组,根据Gensini评分分为轻度和中重度病变组,采用Pearson相关性分析HbA1c、Hcy与冠脉病变相关性。结果单支、轻度病变组HbA1c、Hcy水平低于多支、中重度病变组(P<0.01或0.05)。HbA1c水平与多支病变存在正相关(r=0.103,P<0.05),而Hcy水平与病变严重程度存在正相关(r=0.164,P<0.01)。结论高水平HbA1c、Hcy分别与中老年ACS患者冠脉多支、中重度冠脉病变发生有关。

关键词：糖化血红蛋白同型半胱氨酸急性冠脉综合征

The Changes of Coronary Artery Stenosis on FCG-A New Method of Diagnosing Ischemia Heart Disease

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心脏杂志 1989年第1期 24-32页

作者： Zang Yimin Zhu Miaozhang Chen Shiliang xie An Yang Jiqing chou Xiaodong Jiang Weiping Pan Jianxin Shen Xiguang Department of Physiology Fourth Military Medical University Xi'an China Department of Physiology Fourth Military Medical University Xi'an China Department of Physiology Fourth Military Medical University Xi'an China Department of Physiology Fourth Military Medical University Xi'an China Department of Physiology Fourth Military Medical University Xi'an China Department of Physiology Fourth Military Medical University Xi'an China WEX Medical Instrumentation Co. Ltd Hcng kong WEX Medical Instrumentation Co. Ltd Hcng kong WEX Medical Instrumentation Co. Ltd Hcng kong

Frequency domain correlative cardiogram (FCG) is a new developing technique in noninvasive measurement. It is not clear that FCG diagnoses cardiac ischemia. This study was made cn dogs with different degree of coronary artery stenosis, the relationship between the changes of cardiac ischemia and FCG is discussed in this *** open chest dogs, an external stenosis was produced by a micrometer constrictor cn the left circumflex coronary artery or the left anterior dis-cending coronary artery, which caused three different degrees of coronary artery stenosis: namely mild, moderate and severe stenosis. Coronary blood flow (CBF), aortic pressure, left ventricular pressure, systolic time intervals, admittance plethysmography, two-dimensional echocardiography and FCG were synchronously *** result showed that FCG did not change when CBF was slightly decreased; FCG had a significant change when CBF was decreased to 40% of resting value; there was a remarkable change in FCG when CBF was decreased to 80% of resting value. The amplitude of change in FCG was in concordance with that of decreased CBF. A positive correlation between the changes of FCG and CBF was *** we think that FCG is a valuable diagnostic method for myocardial ischemia when CBF is obviously decreased. It can reflect the degree and extensiveness of myocardial ischemia.

关键词： coronary blood flow coronary artery stenosis hemodynamics frequency-domain correlative cardiogram

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宽波束双基地高频雷达海杂波谱特性研究

哈尔滨工程大学学报 2010年第12期31卷 1573-1579页

作者：仇永斌张宁谢俊好哈尔滨工业大学电子工程技术研究所黑龙江哈尔滨150001

双基地角在杂波单元内的连续变化导致宽波束双基地高频雷达的海杂波谱不同于窄波束.为了揭示这种差异,在G ill和W alsh窄波束双基地海面雷达散射截面积(RCS)基础上,提出了宽波束双基地海面RCS模型;结合高频地波雷达方程,得到宽波束双基... 详细信息

双基地角在杂波单元内的连续变化导致宽波束双基地高频雷达的海杂波谱不同于窄波束.为了揭示这种差异,在G ill和W alsh窄波束双基地海面雷达散射截面积(RCS)基础上,提出了宽波束双基地海面RCS模型;结合高频地波雷达方程,得到宽波束双基地海杂波功率谱密度模型,通过仿真计算得到海杂波谱的具体形态.理论分析和仿真结果表明,在发射机附近以及基线附近的雷达探测区域,宽波束海杂波谱具有明显的展宽效应.

关键词：双基地高频雷达双基地海杂波双基地海面RCS 宽波束

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T/R-R高频地波雷达舰船探测范围分析

电波科学学报 2010年第2期25卷 234-239页

作者：谢俊好李波仇永斌张宁哈尔滨工业大学电子与信息工程学院黑龙江哈尔滨150001

基于目标回波和海杂波、大气噪声相对强度,理论分析及仿真研究了T/R-R高频地波雷达系统对舰船目标探测范围。分别分析了单基地(T/R)、双基地(T-R)高频地波雷达方程;基于T/R、T-R雷达系统海杂波理论模型,仿真了高频地波雷达一、二阶海杂... 详细信息

基于目标回波和海杂波、大气噪声相对强度,理论分析及仿真研究了T/R-R高频地波雷达系统对舰船目标探测范围。分别分析了单基地(T/R)、双基地(T-R)高频地波雷达方程;基于T/R、T-R雷达系统海杂波理论模型,仿真了高频地波雷达一、二阶海杂波谱;提出了计算加权平均信杂比方法,从信杂比的角度分别确定T/R、T-R高频地波雷达系统的探测范围,T/R-R高频地波雷达系统的探测范围为T/R和T-R系统探测范围的组合。

关键词：高频地波雷达探测范围海杂波大气噪声

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采用零排放新工艺处理蚀刻废液

环境污染与防治 2006年第12期28卷 944-946页

作者：谢逢春仇嘉英华南理工大学广东广州510640 广州市白云区南溪化工厂广东广州510545

广州市某化工厂开发出一套对线路板蚀刻废液进行大规模集中资源化处理的零排放处理新工艺,该工艺通过在固相条件下生成氧化铜并用重力分选的方法将其分离出来,克服了原有工艺的缺陷,使废液中所有的成分能够在较低的处理成本下全部分离回... 详细信息

广州市某化工厂开发出一套对线路板蚀刻废液进行大规模集中资源化处理的零排放处理新工艺,该工艺通过在固相条件下生成氧化铜并用重力分选的方法将其分离出来,克服了原有工艺的缺陷,使废液中所有的成分能够在较低的处理成本下全部分离回收,无三废排出,达到了清洁生产的要求。对其工艺条件进行深入研究,通过正交试验优化了工艺条件。

关键词：蚀刻废液正交试验重力分选零排放