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Analysis of Semi-Supervised Text Clustering Algorithm on Marine Data

Computers, Materials & Continua 2020年第7期64卷 207-216页

作者： Yu Jiang Dengwen Yu Mingzhao Zhao Hongtao bai chong Wang Lili He College of Computer Science and Technology Jilin UniversityChangchun130012China A Key Laboratory of Symbolic Computation and Knowledge Engineering Jilin UniversityChangchun130012China Department of Engineering Mechanics State Marine Technical University of St.PetersburgSt.Petersburg190008Russia

Semi-supervised clustering improves learning performance as long as it uses a small number of labeled samples to assist un-tagged samples for learning.This paper implements and compares unsupervised and semi-supervised clustering analysis of BOA-Argo ocean text data.Unsupervised K-Means and Affinity Propagation(AP)are two classical clustering algorithms.The Election-AP algorithm is proposed to handle the final cluster number in AP clustering as it has proved to be difficult to control in a suitable range.Semi-supervised samples thermocline data in the BOA-Argo dataset according to the thermocline standard definition,and use this data for semi-supervised cluster analysis.Several semi-supervised clustering algorithms were chosen for comparison of learning performance:Constrained-K-Means,Seeded-K-Means,SAP(Semi-supervised Affinity Propagation),LSAP(Loose Seed AP)and CSAP(Compact Seed AP).In order to adapt the single label,this paper improves the above algorithms to SCKM(improved Constrained-K-Means),SSKM(improved Seeded-K-Means),and SSAP(improved Semi-supervised Affinity Propagationg)to perform semi-supervised clustering analysis on the data.A DSAP(Double Seed AP)semi-supervised clustering algorithm based on compact seeds is proposed as the experimental data shows that DSAP has a better clustering effect.The unsupervised and semi-supervised clustering results are used to analyze the potential patterns of marine data.

关键词： Unsupervised learning semi-supervised learning text clustering

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Development of a novel platform for recombinant protein production in Corynebacterium glutamicum on ethanol

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Synthetic and Systems Biotechnology 2022年第2期7卷 765-774页

作者： Xinyu Yu Xiuxia Liu Xiong Gao Xunxun Luo Yankun Yang Ye Li Chunli Liu chong Zhang Zhonghu bai Key Laboratory of Industrial Biotechnology Ministry of EducationSchool of BiotechnologyJiangnan UniversityWuxiChina National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing Jiangnan UniversityWuxiChina Division of Life Science The Hong Kong University of Science and TechnologyClear Water BayHong KongChina Jiangsu Provincial Research Center for Bioactive Product Processing Technology Jiangnan UniversityWuxiChina MOE Key Laboratory for Industrial Biocatalysis Institute of Biochemical EngineeringDepartment of Chemical EngineeringTsinghua UniversityBeijingChina Center for Synthetic and Systems Biology Tsinghua UniversityBeijingChina

Corynebacterium glutamicum represents an emerging recombinant protein expression factory due to its ideal features for protein secretion,but its applicability is harmed by the lack of an autoinduction system with tight regulation and high yield.Here,we propose a new recombinant protein manufacturing platform that leverages ethanol as both a delayed carbon source and an inducer.First,we reanalysed the native inducible promoter PICL from the acetate uptake operon and found that its limited capacity is the result of the inadequate translation initial architecture.The two strategies of bicistronic design and ribozyme-based insulator can ensure the high activity of this promoter.Next,through transcriptional engineering that alters transcription factor binding sites(TFBSs)and the first transcribed sequence,the truncated promoter PA256 with a dramatically higher transcription level was generated.When producing the superfolder green fluorescent protein(sfGFP)under 1%ethanol conditions,PA256 exhibited substantially lower protein accumulation in prophase but an approximately 2.5-fold greater final yield than the strong promoter PH36.This superior expression mode was further validated using two secreted proteins,camelid antibody fragment(VHH)and endoxylanase(XynA).Furthermore,utilizing CRISPRi technology,ethanol utilization blocking strains were created,and PA256 was shown to be impaired in the phosphotransacetylase(PTA)knockdown strains,indicating that ethanol metabolism into the tricarboxylic acid cycle is required for PA256 upregulation.Finally,this platform was applied to produce the“de novo design”protein NEO-2/15,and by introducing the N-propeptide of CspB,NEO-2/15 was effectively secreted with the accumulation 281 mg/L obtained after 24 h of shake-flask fermentation.To the best of our knowledge,this is the first report of NEO-2/15 secretory overexpression.

关键词： Corynebacterium glutamicum Ethanol Transcriptional engineering Secretory protein overexpression NEO-2/15

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经支气管镜治疗周围型肺癌

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中华结核和呼吸杂志 2020年第6期43卷 534-539页

作者：孔晨白冲海军军医大学长海医院呼吸与危重症医学科上海200433

早期肺癌的主流治疗方式是手术。然而,许多患者因各种原因无法手术而选择替代治疗。经支气管镜介入技术因其侵入性更小且有更多治疗方式的选择,成为可行的替代疗法。本文综述了支气管镜治疗周围型肺癌的几种主要的方法。

关键词：周围型肺癌射频消融微波消融光动力疗法蒸汽消融冷冻消融

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A Revised Satellite Cloud-Derived Wind Inversion Algorithm Based on Computer Cluster

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Computers, Materials & Continua 2020年第7期64卷 373-388页

作者： Lili He Zhiwei Cai Dantong Ouyang Changshuai Wang Yu Jiang chong Wang Hongtao bai College of Computer Science and Technology Jilin UniversityChangchun130012China Symbol Computation and Knowledge Engineer of Ministry of Education Jilin UniversityChangchun130012China Department of Engineering Mechanics State Marine Technical University of St.PetersburgSt.Petersburg190008Russia

In view of the satellite cloud-derived wind inversion has the characteristics of large scale,intensive computing and time-consuming serial inversion algorithm is very difficult to break through the bottleneck of efficiency.We proposed a parallel acceleration scheme of cloud-derived wind inversion algorithm based on MPI cluster parallel technique in this paper.The divide-and-conquer idea,assigning winds vector inversion tasks to each computing unit,is identified according to a certain strategy.Each computing unit executes the assigned tasks in parallel,namely divide-and-rule the inversion task,so as to reduce the efficiency bottleneck of long inversion time caused by serial time accumulation.In the scheme of parallel acceleration based on MPI cluster,an algorithm based on performance prediction is proposed to effectively implement load balance of MPI clusters.Through the comparative analysis of experiment data using the parallel scheme of this parallel technology framework,it shows that this parallel technology has a certain acceleration effect on the cloud-derived wind inversion algorithm.The speedup of the MPI-based parallel algorithm reaches 14.96,which achieved the expected estimate.At the same time,this paper also proposes an efficiency optimization algorithm for cloud-derived wind inversion.In the case that the inversion of wind vector accuracy loss is minimal,the optimized algorithm execution time can be up to 13 times faster.

关键词： Cloud-derived wind wind vector inversion parallel computing MPI speedup ratio

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SPECIAL ISSUE： DISTRIBUTION OF NATIONAL INCOME IN A TRANSITIONAL ECONOMY Introduction

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Social Sciences in China 2009年第4期30卷 126-130页

作者： bai chong'en Economics Department School of Economics and Management Tsinghua University

本文以2004年经济普查后修订的资金流量表为基础，依次从国民收入的初次分配和再分配两个阶段，分析了1992—2005年期间我国国民收入在企业、政府和居民三部门之间分配格局的变化，重点讨论了自1996年以来居民收入占比下降的原因。在分... 详细信息

本文以2004年经济普查后修订的资金流量表为基础，依次从国民收入的初次分配和再分配两个阶段，分析了1992—2005年期间我国国民收入在企业、政府和居民三部门之间分配格局的变化，重点讨论了自1996年以来居民收入占比下降的原因。在分析初次分配格局时，本文将每个部门的初次分配收入占比表示为各要素分配份额按各要素收入中该部门所占比重加权得到的加权平均值。利用这一表示方式，我们校正了资金流量表中的要素分配份额，重新计算了1993—2005年间的国民收入分配格局，并推算了2006和2007年的国民收入分配格局。测算结果表明，居民部门在全国可支配收入中的占比在1996年达到最高，此后逐年降低，截止N2005年，总共下降了12．72个百分点。在初次分配和再分配阶段，居民部门分别下降了10．71和2．01个百分点。与之相对应，企业和政府部门在初次分配中的占比分别上升了7．49和3．21个百分点；在再分配阶段，居民和企业部门收入占比都下降，由此导致政府部门进一步上升3．17个百分点。我们还发现，国民收入的要素分配中劳动收入占比下降和财产收入占比下降，是居民部门在国民收入初次分配中占比下降的两个主要原因。在2005—2007年间，主要受生产水净额占比上升的影响，居民部门在国民收入中占比进一步下降了3个百分点以上．

关键词：收入分配国民收入转型经济简介家庭收入社会稳定经济发展劳动力

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多灶性浸润性肺癌组织学诊断的研究进展

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中华病理学杂志 2023年第4期52卷 427-430页

作者：田森石荟白冲海军军医大学第一附属医院呼吸与危重症医学科上海200433

在多灶性浸润性肺癌患者中,准确区分多原发肺癌和肺内转移具有重要的临床意义,但对于病理学家而言也具有一定的挑战性。近年来,随着分子生物学技术的发展,人们对肿瘤间克隆关系有了更深入的认识,综合组织学评估及其衍生的其他方法是目... 详细信息

在多灶性浸润性肺癌患者中,准确区分多原发肺癌和肺内转移具有重要的临床意义,但对于病理学家而言也具有一定的挑战性。近年来,随着分子生物学技术的发展,人们对肿瘤间克隆关系有了更深入的认识,综合组织学评估及其衍生的其他方法是目前临床上用来分类多灶性浸润性肺癌的主要组织学方法,而与可以明确肿瘤间克隆关系的分子学方法相结合,将会成为未来区分多原发肺癌和肺内转移的发展方向。

关键词：组织学诊断病理学家组织学方法多灶性多原发肺癌肺内转移浸润性分子生物学技术

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刘宋“诗运转关”考论

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中国文学研究 2015年第1期 65-68页

作者：白崇广东技术师范学院中文系广东广州510665

刘宋时期中古诗歌发生转型,因而被人称为"诗运转关"。"诗运转关"有三层含义:一是刘宋诗歌从玄言诗的阴影中走出,回归到魏晋诗歌传统上,得以健康发展;二是刘宋诗歌在声律、对仗等艺术上取得了巨大的成就,启迪了后来的"永明体",在中国古... 详细信息

刘宋时期中古诗歌发生转型,因而被人称为"诗运转关"。"诗运转关"有三层含义:一是刘宋诗歌从玄言诗的阴影中走出,回归到魏晋诗歌传统上,得以健康发展;二是刘宋诗歌在声律、对仗等艺术上取得了巨大的成就,启迪了后来的"永明体",在中国古典诗歌发展的历程中具有转折意义;三是以谢灵运为代表的清丽诗风和以鲍照、汤惠休为代表的俗艳诗风改变了魏晋以来以渊奥、典雅为主导的诗歌格局,促进了诗风的多样化发展。

关键词：刘宋诗歌诗运转关元嘉体休鲍之风

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Bronchial thermoplasty

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Chinese Medical Journal 2013年第17期126卷 3375-3378页

作者： Javier Diaz-Mendoza ] bai chong HUANG Hai-dong Michael J. Simoff Interventional Pulmonology Division of Pulmonary and Critical Care Medicine Henry Ford Health System Detroit Michigan United States of America Department of Respiratory Diseases Changhai Hospital Second Military Medical University Shanghai 200433 China

Asthma is a chronic inflammatory disease that affects 300 million people worldwide. Its prevalence rangesfrom 1% to 18% of the population in different countries. The World Health Organization has estimated that 15 million disability-adjusted life years are lost annually due to asthma. Worldwide deaths from asthma are estimated at 250 000 per year. Furthermore, asthma is a major cause of absence from work in many countries, including United States .

关键词： asthma bronchial thermoplasty airway smooth muscle

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3D graphene foam-supported cobalt phosphate and borate electrocatalysts for high-efficiency water oxidation

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科学通报：英文版 2015年第16期60卷 1426-1433页

作者： Min Zeng Hao Wang chong Zhao Jiake Wei Wenlong Wang Xuedong bai Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences

The cobalt phosphate-/cobalt borate-based oxygen-evolving catalysts(OECs) are the important class of earth-abundant electrocatalysts that can operate with high activity for water splitting under benign conditions.This article reports the integration of cobalt phosphate(CoPi) and cobalt borate(Co-Bi) OECs with three-dimensional(3D) graphene foam(GF) for the electrocatalytic water oxidation reaction. The GF showed a unique advantage to serve as a highly conductive 3D support with large capacity for anchoring and loading Co-OECs, thereby facilitating mass and charge transfer due to the large amount of active sites provided by the 3D graphene scaffold. As a result, this integrated system of GF and Co-OECs exhibits synergistically enhanced catalytic activity. The overpotential(g) of Co-Pi and Co-Bi/graphene catalysts is about 0.390 and0.315 V in neutral solutions, respectively. Besides, the integrated Co-OECs/graphene catalysts have also exhibited improved and stable oxygen evolution catalytic ability in alkaline solution.

关键词：磷酸盐催化剂氧化钴硼酸盐分解水石墨三维泡沫嗅鞘细胞

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Pair production in strong SU（2） background fields

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Frontiers of physics 2017年第5期12卷 143-150页

作者： Mo-Ran Jia Zi-Liang Li chong Lv Feng Wan bai-Song Xie College of Nuclear Science and Technology Beijing Normal University Beijing 100875 China Beijing Radiation Center Beijing 100875 China

强壮的苏(2 ) 计量器 chromoelectric 领域里的费米子粒子对生产以一个古典方法用 Boltzmann-Vlasov 方程被学习。在古典描述的一个 preproduction 过程的存在用 non-Abelian 粒子生产的分发进化被显示出。发现粒子数字密度的分发在二... 详细信息

强壮的苏(2 ) 计量器 chromoelectric 领域里的费米子粒子对生产以一个古典方法用 Boltzmann-Vlasov 方程被学习。在古典描述的一个 preproduction 过程的存在用 non-Abelian 粒子生产的分发进化被显示出。发现粒子数字密度的分发在二个岛上被集中并且当它演变，在颜色费用范围上显示出一个裂口有趣，最终到达与这个领域的振幅和变化有关的一个稳定的状态。

关键词： SU(2) 背景场 Boltzmann Vlasov方程粒子数密度试制过程演化过程稳定状态

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