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Poly caprolactone/titanium dioxide nanofiber coating on AM50 alloy for biomedical application

Journal of Magnesium and Alloys 2021年第2期9卷 532-547页

作者： Mani Karthega Mogan Pranesh chockalingam poongothai Nagarajan Srinivasan Department of Sciences Amrita School of EngineeringCoimbatoreAmrita VishwaVidyapeethamIndia Department of Chemistry Manonmaniam Sundaranar UniversityTirunelveliIndia

Poly caprolactone(PCL)and Poly caprolactone/TiO_(2)(PCL/TiO_(2))composite nanofiber with different weight percentage compositions(2 wt%,4 wt%and 6 wt%)of TiO_(2)were prepared and coated over AM50 alloy using electrospinning *** surface morphology and elemental composition result confirms that the PCL/TiO_(2)composite nanofiber fiber were successfully electrospun on the surface of AM50 *** degradation behavior of PCL and PCL/6 wt%TiO_(2)coated AM50 alloy was studied by immersing in Simulated Body Fluid(SBF)*** electrochemical and cell proliferation studies reveals that the cellular behavior of PCL and PCL/6 wt%TiO_(2)composite nanofiber exhibited good support for cell proliferation with enhanced corrosion resistance of AM50 alloy in SBF solution.

关键词： Electrospinning AM50 alloy Polycaprolactone Biocompatible Corrosion resistance Electrochemical studies

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Antihyperglycemic and antioxidant effects of Solanum xanthocarpum leaves(field grown & in vitro raised) extracts on alloxan induced diabetic rats

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Asian Pacific Journal of Tropical Medicine 2011年第10期4卷 778-785页

作者： K poongothai P Ponmurugan K Syed Zameer Ahmed B Senthil Kumar SA Sheriff Research and Development Centre Bharathiar UniversityCoimbatore-646041Tamil NaduIndia Department of Biotechnology K.S.Rangasamy College of TechnologyK.S.R.KalvinagarThiruchengode-637215Tamil NaduIndia Department of Biotechnology K.S.Ranga.samy College of TechnologyK.S.R.KalvinagarThiruchengode-637215Tamil NaduIndia Department of Biochemistry C.Abdul Hakeem CollegeMelvisharam-632509Tamil NaduIndia Department of Zoology Thiruvalluvar UniversitySerkaduVelloreTamil NaduIndia Department of Biochemistry College of Applied Medical SciencesShaqra UniversityShaqra-11961.Kingdom of Saudi Arabia

Objective:To investigate antidiabetic efficacy of the extract of field grown and in vitro raised leaves of Solanum xanthocarpum(***) against alloxan induced diabetic rats. Methods:The antidiabetic activity of the crude methanol extracts of the field grown and in vitro raised leaves of *** at different concentrations(100-200 mg/kg bw) was tested against alloxan induced diabetic *** antidiabetic efficacy was validated through various biochemical parameters and the antioxidant effect was also *** phytochemical analyses of field grown *** and in vitro rasied *** leaves were done by estimating their chlorophyll,carotenoids,total sugar,protein,amino acid and minerals contents. Results:The results revealed that the methanol extracts of both the leaves(field grown and in vitro raised) of *** was efficient anti hyperglycemic agents at a concentration of 200 mg/kg bw and posses potent antioxidant ***,the extracts of in vitro rasied *** raised leaves exhibit higher efficacy than the field grown leaves in all tested *** composition and mineral analysis of *** revealed higher concentration of contents in in vitro rasied *** than field grown ***. Conclusions:From the results it can be concluded that the leaves extracts of *** can be a potential candidate in treating the hyperglycemic conditions and suits to be an agent to reduce oxidative stress.

关键词： Solanum Xanthocarpum Alloxan Field grown In vitro Oxidative stress Antioxidant Hyperglycemia Hypolipidemic

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