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Massive pulmonary embolism in Klippel-Trenaunay syndrome after leg raising:A case report

World Journal of Clinical Cases 2023年第17期11卷 4133-4141页

作者： Chih-Yu Lo Kuen-Bao Chen Li-Kuei Chen chiuan-shiou chiou Department of Anesthesiology China Medical University HospitalTaichung 40447Taiwan Department of Anesthesiology Pain Service and Critical Care Medicine China Medical University HospitalTaichung 40447Taiwan

BACKGROUND Klippel-Trenaunay syndrome(KTS)is a rare congenital disorder characterized by a combination of capillary malformations,soft-tissue or bone hypertrophy,and varicose veins or venous *** syndrome predisposes patients to hypercoagulable states,including venous thromboembolism and pulmonary embolism(PE).CASE SUMMARY A 12-year-old girl with KTS was scheduled excision of verrucous hyperkeratosis in the left foot and posterior aspect of the left leg and left thigh and excision of a cutaneous hemangioma in the right *** induction,the surgeon elevated the patient’s leg for sterilization,whereupon she experienced a massive PE and refractory cardiac *** membrane oxygenation(ECMO)was performed after prolonged resuscitation,and she had a return of spontaneous *** this episode,the patient was discharged without any neurologic *** The mechanism of PE,a lethal disease,involves a preexisting deep vein thrombosis that is mechanically dislodged by compression or changing positions and travels to the pulmonary ***,patients predisposed to PE should be prescribed prophylactic *** the patient has unstable vital signs,resuscitation should be started immediately,and extracorporeal cardiopulmonary resuscitation should be considered in settings with existing ECMO protocols,expertise,and *** of PE in patients with KTS while leg raising for sterilization is critical.

关键词： Klippel-Trenaunay syndrome Pediatric Pulmonary embolism Anesthesia Case report

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Study of the protective efects of glucosamine-based formulation for rosacea

Study of the protective efects of glucosamine-based formulat...

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中国毒理学会第九次全国青年科技大会暨第二届生物技术药物毒理与安全评价委员会学术会议

作者： Xie An Yun-Rong Tsai Yi-Chia Chen Ying-Chi Lin Hsiao-Ping Lee Yi-shiou chiou College of Pharmacy Kaohsiung Medical University School of pharmacy Kaohsiung Medical University

Objective Glucosamine(GlcN) is an aminomonosaccharide that as an active ingredient for skin care ***,the present study was aimed to develop a safe and effective GlcN-based formulation to prevent the rosacea-like *** and Methods Cytotoxicity was studied on human fibroblasts CCD966 SK and on keratinocytes HaCaT by MTT *** effects of matrix metalloproteinases(MMPs) and pro-inflammatory cytokines of GlcN-based formulations were evaluated by gelatin zymography and ELISA *** genotoxic effects of GlcN-based formulations were analyzed using the alkaline single cell gel electrophoresis assay(comet assay) and Ames test.A rosacea-like BALB/c mouse model injected with LL-37 was used to determine the role of GlcN-based formulations in rosacea in *** We found that GlcN-based samples B showed no cytotoxic and genotoxic effects,thus establishing safe and effective dosing basis for future skin care product *** addition,it was found that GlcN-based samples B attenuated local redness,inflammation,and neutrophil recruitment via inhibiting proinflammatory cytokines in the mouse model of rosacea in *** All these findings suggest that GlcN-based sample B presented multiple skin care *** conclusion,the GIcNbased formulation could serve as a promising candidate drug or cosmetics ingredient for rosacea.

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以RuO_2为基的厚膜电阻器中电子传导与温度的关系

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电子产品可靠性与环境试验 1994年第2期12卷 16-22页

作者： BI-shiou chiou JER-YUAN SHEN 王光明台湾

本文研究了两种同属RuO_2为基的厚膜电阻器中阻值与温度的关系。两种电阻器的成分(重量百分比,下同)分别为:80%玻璃料(其中:63%pbO-25%B_2O_3-12%SiO_2,称作G_1)-20%RuO_2和80%玻璃料(其中:55.5%pbO-22%B_2O_3-10.5%SiO_2-12%Al_2O_3,称作G_2)-20%RuO_2.成分为80%G_1-20%RuO_2的电阻器在850℃下烧结后,当温度从100K到～400K上升时方阻变小,并在400K到～690K之间保持一个最小值,然后随温度的进一步升高而变大.在100K～500K时获得的负温度系数为～480ppm/℃;当温度再升高时,电阻温度系数(TCR)变得更小. 本文使用厚膜电阻器导电机理的三种传导方式解释了实验结果;用一种改进的传导方式(包详隧道传导和并联传导两种方式),说明了阻值-温度反比曲线的坡度变化和阻值与温度的关系;另外还用一个等效电路模式阐述了厚膜电阻器的电性能.

关键词：厚膜电阻器电子传递温度 RuO2

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