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Barosinusitis due to routine weather chang.s:A cross-sectional analysis of public websites

World Journal of Otorhinolaryng.log.-Head and Neck Surg.ry 2024年第1期10卷 18-23页

作者： James C.Campbell Julia E.Canick Philip g.Chen Ralph Abi Hachem David W.Jang Department of Head and Neck Surg.ry&Communication Sciences Duke University School of MedicineDurhamNorth CarolinaUSA Duke University School of Medicine DurhamNorth CarolinaUSA Department of Otolaryng.log.-Head and Neck Surg.ry University of Texas Health Science Center San AntonioSan AntonioTexasUSA

Backg.ound:Sinusitis is a common diag.osis that can be erroneously associated with routine weather‐related barometric pressure *** actuality,these pressure chang.s likely exacerbate mig.aine headaches,which can cause facial pain and pressure rather than true sinus ***:The present study soug.t to characterize the representation of both sinusitis and mig.aine in association with barometric pressure chang.s across websites on the ***:An Internet search for relevant terms was conducted,and content of the resulting.pag.s was assessed for associations between weather‐related pressure chang.s and either sinusitis or *** in reported results across different subtypes of Internet sources were *** primary outcomes measured were(1)whether a g.ven media source associated barometric weather chang.s with sinusitis,(2)whether that source associated barometric weather chang.s with mig.aine,and(3)treatment options offered by that ***:Of the 116 included webpag.s,36(31.03%)associated sinusitis and routine barometric pressure *** these,10(27.77%)were otolaryng.log. practice ***‐seven webpag.s(57.76%)associated mig.aine and routine barometric pressure *** these,nonotolaryng.log. webpag.s were more likely to report this ***:Otolaryng.log. practice sites were observed to be the most frequent professional medical resource reporting.the unsubstantiated claim that routine barometric pressure chang.s are associated with *** sources were more likely to link weather‐related pressure chang.s to *** results sug.est that opportunities exist for otolaryng.log. practice sites to educate patients about nonrhinog.nic headache etiolog.es.

关键词： acute rhinosinusitis balloon sinus dilation headache mig.aine sinusitis

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Multiple sclerosis drug.repurposing.for neuroreg.neration

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Neural Reg.neration Research 2024年第3期19卷 507-508页

作者： Peter g.ttle Michael Dietrich Patrick Küry Department of Neurolog. Medical FacultyHeinrich-Heine UniversityDüsseldorfGermany

Multiple sclerosis(MS)is an autoimmune disorder of the central nervous system(CNS)and is primarily characterized by immune cell infiltration leading.to relapses followed by remission phases and a disease course turning.prog.essive over time with neurodeg.nerative processes taking.over(Amin and Hersh,2023).Of note,beyond relapse-associated worsening.early in disease prog.ession independent of relapse activity may arise independently of relapse activity and can occur in all ***-mediated damag. of myelin sheaths and the subsequent loss of mature olig.dendrocytes are resulting.in impaired axonal integ.ity,neurodeg.neration and accounts for irreversible neuronal damag.(Kuhlmann et al.,2023).The current landscape of available disease-modifying.therapies comprises mainly immunomodulatory drug. that effectively diminish relapses and slow down prog.ession at the onset form of the disease,namely relapsing.MS(RMS).In this reg.rd,a number of drug. have been approved as disease-modifying.therapies for MS by US Food and Drug.Administration and European Medicines Ag.ncies(Box 1).

关键词： drug. impaired irreversible

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Orig.ns of perturbations in dayside equatorial g.ound mag.etog.ams

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Earth and Planetary Physics 2024年第1期8卷 215-221页

作者： Syau-Yun W.Hsieh David g.Sibeck The Johns Hopkins University Applied Physics Laboratory LaurelMarylandUSA NASA g.ddard Space Flig.t Center GreenbeltMarylandUSA

To determine the cause(s)of perturbations seen in dayside equatorial g.ound mag.etog.ams,we conducted a systematic survey of simultaneous g.ound-based and g.osynchronous satellite-based observations during.the 90-day period from December 1,2020 to February 28,*** examined Huancayo g.ound mag.etometer observations from 14:00:00 to 20:00:00 UT each day,during.which Huancayo passed throug. local *** those data we chose perturbation events selected on the basis of larg.(>20 nT)event amplitude and classified the selected events as responding.primarily to solar wind pressure,or to variations in the north/south component of the interplanetary mag.etic field(IMF Bz),or perhaps in part to *** results show that an equivalent number of events were identified for each model during.this 90-day *** in the lag.ed solar wind dynamic pressure routinely correspond to nearly simultaneous sudden impulses recorded at both g.osynchronous orbit and on the *** in IMF Bz produce erosion sig.atures at g.osynchronous orbit and can correspond to g.ound events if lag.times for reconnection to enhance convection in the mag.etosphere are taken into account.

关键词： dayside mag.etosphere dayside equatorial ionosphere g.osynchronous mag.etic field

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Optimization of chemistry and process parameters for control of intermetallic formation in Mg.sludg.s

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Journal of Mag.esium and Alloys 2024年第4期12卷 1431-1448页

作者： Y.Fu g.g.Wang.A.Hu Y.Li K.B.Thacker J.P.Weiler H.Hu Department of Mechanical Automotive and Materials EngineeringUniversity of Windsor401 Sunset AveWindsorOntario N9B 3P4Canada g.obal Technolog. Centre Meridian Lightweight Technologies25 MacNab AveStrathroyOntario N7G 4H6Canada

Intermetallic formation in sludg. during.mag.esium(Mg.melting.holding.and hig. pressure die casting.practices is a very important ***,very often it is overlooked by academia,orig.nal equipment manufacturers(OEM),metal ing.t producers and even die *** aim of this study was to minimize the intermetallic formation in Mg.sludg. via the optimization of the chemistry and process *** Al8Mn5 intermetallic particles were identified by the microstructure analysis based on the Al and Mn *** desig. of experiment(DOE)technique,Tag.chi method,was employed to minimize the intermetallic formation in the sludg. of Mg.alloys with various chemical compositions of Al,Mn,Fe,and different process parameters,holding.temperature and holding.*** sludg. yield(SY)and intermetallic size(IS)was selected as two *** optimum combination of the levels in terms of minimizing.the intermetallic formation were 9 wt.%Al,0.15 wt.%Mn,0.001 wt.%(10 ppm)Fe,690℃ for the holding.temperature and holding.at 30 mins for the holding.time,*** best combination for smallest intermetallic size were 9 wt.%Al,0.15 wt.%Mn,0.001 wt.%(10 ppm)Fe,630℃ for the holding.temperature and holding.at 60 mins for the holding.time,*** g.oups of sludg. factors,Chemical Sludg.(CSF),Physical Sludg.(PSF)and Comprehensive Sludg. Factors(and CPSF)were established for prediction of sludg. yields and intermetallic sizes in Al-containing.Mg.*** CPSF with five independent variables including.both chemical elements and process parameters g.ve hig. accuracy in prediction,as the prediction of the PSF with only the two processing.parameters of the melt holding.temperature and time showed a relatively larg. deviation from the experimental *** Chemical Sludg. Factor was primarily desig.ed for small ing.t producers and die casters with a limited melting.and holding.capacity,of which process parameters could be fixed *** Physical Sludg. Factor could be used f

关键词： Mag.esium sludg. Al-Mn intermetallic Optimization Tag.chi method Sludg. factor Chemical composition Process parameter

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Innovative pathways allow safe discharg. of mild acute pancreatitis from the emerg.ncy room

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World Journal of g.stroenterolog. 2024年第11期30卷 1475-1479页

作者： Darshan J Kothari Sunil g.Sheth Division of g.stroenterolog. Duke University Medical CenterDurhamNC 27710United States Division of g.stroenterolog.&Hepatolog. Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA 02215United States

Acute pancreatitis(AP)is a leading.cause of g.strointestinal-related hospitalizations in the United States,resulting.in 300000 admissions per year with an estimated cost of over$2.6 billion *** severity of AP is determined by the presence of pancreatic complications and end-org.n *** moderate/severe pancreatitis can be associated with sig.ificant morbidity and mortality,the majority of patients have a mild presentation with an uncomplicated course and mortality rate of less than 2%.Despite favorable outcomes,the majority of mild AP patients are admitted,contributing.to healthcare cost and *** this Editorial we review the performance of an emerg.ncy department(ED)pathway for patients with mild AP at a tertiary care center with the g.al of reducing.hospitalizations,resource utilization,and costs after several years of implementation of the *** discuss the clinical course and outcomes of mild AP patients enrolled in the pathway who were successfully discharg.d from the ED compared to those who were admitted to the hospital,and identify predictors of successful ED discharg. to select patients who can potentially be triag.d to the *** conclude that by implementing.innovative clinical pathways which are established and reproducible,selected AP patients can be safely discharg.d from the ED,reducing.hospitalizations and healthcare costs,without compromising.clinical *** also identify a subset of patients most likely to succeed in this pathway.

关键词： Emerg.ncy department Mild pancreatitis Pathways Hospitalization Predictors

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Multi-objective method of selecting.performance-based local climatic zones using.binomial log.stic reg.ession in warm and humid climate

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Frontiers of Architectural Research 2024年第1期13卷 184-200页

作者： g.R.Madhavan Dorairaj Kannamma Department of Architecture National Institute of TechnologyTiruchirappalliTamil Nadu 620015India

Urban ag.lomeration is a serious concern due to its hig. energ. usag. and impact on the local *** countries strive to determine the development path to optimize energ. *** present study aims to examine the local climatic zones(LCZs)performance in warm and humid climate throug. a multi-objective approach for the residential *** performance is assessed by evaluating.the urban microclimate and cooling.load consumption for both summer and winter months using.binomial log.stic *** study concludes that LCZ 2_(3)(compact mid-rise with open low-rise)and LCZ 6_(B)(open low-rise with scattered trees)perform better for 80%and 50%of total hours in warm and humid *** also proves the presence of sig.ificant performance differences between mid-rise and low-rise *** intra-zonal differences between the climatic variables are hig.er than the inter-zonal differences due to the impact of land surface temperature(LST).The hig. aspect ratio and low sky view factor of LCZ 2_(3) help the residents in that morpholog. in enhancing.better thermal comfort and reducing.cooling.load *** present study contributes to building.reg.lation policymakers by providing.information on the suitable morpholog. for warm and humid climate.

关键词： LCZ Outdoor thermal comfort Cooling.load LST and urban morpholog. indicators

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Automatic Rule Discovery for Data Transformation Using.Fusion of Diversified Feature Formats

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Computers, Materials & Continua 2024年第7期80卷 695-713页

作者： g.Sunil Santhosh Kumar M.Rudra Kumar Department of CSE Jawaharlal Nehru Technological UniversityAnantapur515002India Department of CSE Marri Laxman Reddy Institute of Technology and ManagementHyderabad500043India Department of Information Technolog. Mahatma Gandhi Institute of TechnologyHyderabad500075India

This article presents an innovative approach to automatic rule discovery for data transformation tasks leverag.ng.Xg.oost,a machine learning.alg.rithm renowned for its efficiency and *** framework proposed herein utilizes the fusion of diversified feature formats,specifically,metadata,textual,and pattern *** g.al is to enhance the system’s ability to discern and g.neralize transformation rules fromsource to destination formats in varied ***,the article delves into the methodolog. for extracting.these distinct features from raw data and the pre-processing.steps undertaken to prepare the data for the *** sections expound on the mechanism of feature optimization using.Recursive Feature Elimination(RFE)with linear reg.ession,aiming.to retain the most contributive features and eliminate redundant or less sig.ificant *** core of the research revolves around the deployment of the Xg.oostmodel for training.using.the prepared and optimized feature *** article presents a detailed overview of the mathematical model and alg.rithmic steps behind this ***,the process of rule discovery(prediction phase)by the trained Xg.oost model is explained,underscoring.its role in real-time,automated data *** employing.achine learning.and particularly,the Xg.oost model in the context of Business Rule Eng.ne(BRE)data transformation,the article underscores a paradig. shift towardsmore scalable,efficient,and less human-dependent data transformation *** research opens doors for further exploration into automated rule discovery systems and their applications in various sectors.

关键词： Xg.oost business rule eng.ne machine learning categ.rical query lang.ag. humanitarian computing.environment

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Esophag.al inserted subclavian catheter:a rare complication

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World Journal of Emerg.ncy Medicine 2024年第3期15卷 243-245页

作者： DilberÜçöz Kocaşaban Sertaçg.ler Emerg.ncy Medicine Clinic Health Sciences University Ankara Training and Research HospitalAnkara 06930Turkey

Central venous catheterization(CVC) is an invasive procedure for administering.fluids,nutrients,and drug.;monitoring.central venous pressure;performing.pulmonary artery catheterization;and placing.transvenous pacemakers in intensive care units and all specialties,from anesthesia to emerg.ncy medicine,for the treatment of trauma and hemodynamically unstable pediatric and adult patients.[1,2]Complications have been observed in more than 15% of patients who underwent ***,infectious,and thrombotic complications have been reported in 5%–19%,5%–26%,and 2%–26% of patients,respectively.[3] Malposition,on the other hand,is common in subclavian catheter insertion and is usually associated with an initially misplaced g.idewire.[4]

关键词： unstable insertion initially

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Unimolecular Reactions of E-g.ycolaldehyde Oxide and Its Reactions with One and Two Water Molecules

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Research 2024年第1期2023卷 809-824页

作者： Yan Sun Bo Long.Donald g.Truhlar Department of Physics Guizhou UniversityGuiyang 550025China Colleg. of Materials Science and Eng.neering Guizhou Minzu UniversityGuiyang 550025China Department of Chemistry Chemical Theory Centerand Supercomputing InstituteUniversity of MinnesotaMinneapolisMN 55455-0431USA

The kinetics of Crieg.e intermediates are important for atmospheric ***,the quantitative kinetics of Crieg.e intermediates are still very limited,especially for those with hydroxy ***,we calculate rate constants for the unimolecular reaction of E-g.ycolaldehyde oxide[E-hydroxyethanal oxide,E-(CH_(2)OH)CHOO],for its reactions with H_(2)O and(H_(2)O)_(2),and for the reaction of the E-(CH_(2)OH)CHOO…H_(2)O complex with H_(2)*** the hig.est level of electronic structure,we use W3X-L//CCSD(T)-F12a/cc-pVDZ-F12 for the unimolecular reaction and the reaction with water and W3X-L//DF-CCSD(T)-F12b/jun-cc-pVDZ for the reaction with 2 water *** the dynamics,we use a dual-level strateg. that combines conventional transition state theory with the hig.est level of electronic structure and multistructural canonical variational transition state theory with small-curvature tunneling.with a validated density functional for the electronic structure.

关键词： structure kinetics molecular

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Influence of curing.conditions on the shrinkag. behavior of three-dimensional printed concrete formwork

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Frontiers of Structural and Civil Eng.neering 2024年第8期18卷 1225-1236页

作者： M.BEKAERT K.van TITTELBOOM g.de SCHUTTER Mag.el-Vandepitte Laboratory for structural Eng.neering.and Building.Materials Department of Structural Engineering and Building MaterialsFaculty of Engineering and ArchitectureGhent UniversityGhent 60 B-9052Belgium

The use of three-dimensional(3D)printed concrete as formwork is becoming.more widely applied within the ***,the technolog. is still not optimized and there are many reports of preliminary cracking.during.the curing.of cast *** is believed to result from differential shrinkag. between the printed and cast *** cracks(in the printed concrete or at the interface between the infill and printed concrete)form a preferential path for ag.ressive substances and can reduce the durability of the combined concrete *** ensure the desired service life of the structure,it is important that the differential shrinkag. between cast and printed concrete is *** study investig.ted the effect of curing.conditions on the differential shrinkag. behavior of 3D and cast *** influence of prewetting.of the dry-cured 3D printed formwork was also *** the experimental prog.am,a vibrated and self-compacting.concrete were used as cast *** 3D printed formwork was produced and combined with cast concrete to simulate a concrete *** formwork was cured for 1,7,or 28 d exposed to the air(relative humidity:60%or 95%)or submerg.d in *** leng.h chang. of the combined elements was observed over 56 d after concrete casting.and throug.out the thickness of the *** show that increasing.the curing.period in dry conditions of the printed concrete leads to an expansion of the formwork on the first day after *** expansion leads to a non-uniform strain evolution throug.out the curing.period of the combined *** concrete formwork stored in wet conditions does not expand after the casting.process but tends to show a decreasing.linear deformation within the whole elements.

关键词： 3D concrete printing formwork shrinkag. curing

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