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Effect of acupressure on postpartum low back pain, salivary cortisol, physical limitations, and depression: a randomized controlled pilot study

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Journal of Traditional Chinese Medicine 2020年第1期40卷 128-136页

作者： cheng Hsuesh-yu Carol Shieh Wu Bei-yu cheng yu-Fen Department of Nursing Kaohsiung Chang Gung Memorial HospitalKaohsiung 80830Taiwan China Department of Community and Health Systems Indiana University School of NursingIndiana 600USA Department of Chinese Medicine Kaohsiung Chang Gung Memorial HospitalKaohsiung 80830Taiwan China

OBJECTIVE:To investigate the effect of acupressure on postpartum low back pain(LBP),salivary cortisol,physical limitations,and postpartum ***:Participants were 70 postpartum women who were randomly assigned to either an intervention(n=35)or a control(n=35)*** intervention group received 10 acupressure sessions(1 session per day,5 d per week).The control group received 10 sham acupressure *** were assessed using a visual analogue scale(LBP intensity),salivary cortisol values(LBP biomarker),and Chinese versions of the Roland-Morris Disability Questionnaire(daily activity limitations),Oswes-try Disability Index(physical activity limitations),and the Edinburgh Postnatal Depression Scale(postpartum depression).RESULTS:Participants in the intervention group had significantly lower levels of LBP intensity,daily activity limitations,physical activity limitations,and postpartum depression than those in the control *** was no significant between-group difference in salivary ***:Acupressure may reduce postpartum LBP intensity and limitations in daily and physical activity,and alleviate postpartum depressive *** should be offered in postpartum care settings as an alternative treatment for postpartum women with LBP.

关键词： Acupressure Low back pain Postpartum period Depression Randomized controlled trial Pilot projects

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经济不确定性、资产效应与居民消费

云南财经大学学报 2025年第1期41卷 1-18页

作者：李一帆于海东李成中国银行研究院北京100818 中国建设银行研修中心(研究院) 北京100033 西安交通大学经济与金融学院西安710061

构建包含经济不确定性的居民最优消费决策数理模型,推导出经济不确定性影响居民消费的资产效应机制,运用中国家庭追踪调查数据,设立省际经济不确定性指数,并进行实证检验。研究发现:整体上看,经济不确定性通过资产效应机制降低了居民消... 详细信息

构建包含经济不确定性的居民最优消费决策数理模型,推导出经济不确定性影响居民消费的资产效应机制,运用中国家庭追踪调查数据,设立省际经济不确定性指数,并进行实证检验。研究发现:整体上看,经济不确定性通过资产效应机制降低了居民消费支出。经济不确定性上升引发市场系统性风险上升,提高了居民资产的风险溢价,迫使资产价值缩水,降低了居民对风险资产市场的投资意愿和参与程度,导致资产性收入下降,最终抑制居民消费支出。结构上看,经济不确定性主要通过降低房产价值和资产性收入的路径抑制消费支出,其中承担房贷的居民受经济不确定性的负向影响更明显,消费缩减程度更大。由于国内居民资产配置结构不均衡,金融产品对家庭消费的资产效应相对较弱,经济不确定性难以通过股票等金融资产价值和金融市场参与度影响消费。

关键词：经济不确定性资产效应居民消费资产性收入

Novel bake hardening mechanism for bainite-strengthened complex phase steel

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Journal of Materials Science & Technology 2023年第12期143卷 117-128页

作者： Hang yu yu Yan cheng Zhang Lijie Qiao Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijing 100083China Corrosion and Protection Center University of Science and Technology BeijingBeijing 100083China

In the automobile industry,stamping and paint baking processes are used to strengthen components,and this not only saves costs,but also further reduces the bodyweight of *** this work,the bake hardening mechanism of the complex phase(CP)steel CP980 was explored by comparing it with that of DP1180,which has a clear bake hardening mechanism and a carbon content similar to that of *** analyzing the bake hardening response and the microstructural changes of the two steels,we found that the bake hardening process of CP980 was divided into three *** the first two stages,the carbon atoms diffused into dislocations to form Cottrell atmosphere pinning dislocations,and excess car-bon atoms formed carbon clusters or low-temperature carbide pinning dislocations that were similar to *** the third stage,the dislocation acted as rapid channels for carbon diffusion,and fine cementite gradually formed when the carbon clusters gathered at the dislocations as precursors,resulting in pre-cipitation *** novel bake-hardening(BH)mechanism is crucial for obtaining a comprehensive understanding of the strain-baking behavior of advanced high-strength steals(AHSS).

关键词： Age hardening Bainitic steel Carbon diffusion Cementite Mechanical property Automotive weight reduction

The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury

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Neural Regeneration Research 2023年第11期18卷 2482-2488页

作者： Zhengran yu Xing cheng Wenxu Pan cheng yu Yang Duan Department of Spine Surgery Orthopedics Center of Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhouGuangdong ProvinceChina Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Department of Gastroenterology Guangzhou Women and Children’s Medical CenterJinan UniversityGuangzhouGuangdong ProvinceChina Department of Spine Surgery Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

Chronic compressive spinal cord injury in compressive cervical myelopathy conditions can lead to rapid neurological deterioration in the early phase,followed by partial self-recovery,and ultimately an equilibrium state of neurological *** is a crucial pathological process in many neurodegenerative diseases;however,its role in chro nic compressive spinal cord injury remains *** this study,we established a chronic compressive spinal cord injury rat model,which displayed its most severe behavioral and electrophysiological dysfunction at 4 wee ks and partial recovery at 8 weeks after *** RNA sequencing data identified enriched functional pathways,including ferroptosis,presynapse,and postsynaptic membrane activity at both 4 and 8 wee ks following chro nic compressive spinal co rd *** nsmission electron microscopy and malondialdehyde quantification assay confirmed that ferroptosis activity peaked at 4 weeks and was attenuated at 8 weeks after chronic *** ptosis activity was negatively correlated with behavioral ***,quantitative polymerase chain reaction,and western blotting showed that expression of the anti-ferroptosis molecules,glutathione peroxidase 4(GPX4) and MAF BZIP transcription factor G(MafG),in neuro ns was suppressed at 4 weeks and upregulated at 8 weeks following spinal co rd *** was a positive correlation between the expression of these two molecules,suggesting that they may work together to contribute to functional recovery following chronic compressive spinal cord *** conclusion,our study determined the genome-wide expression profile and fe rroptosis activity of a consistently compressed spinal cord at different time *** results showed that anti-fe rroptosis genes,specifically GPX4 and MafG,may be involved in spontaneous neurological recovery at 8 weeks of chronic compressive spinal cord *** findings contribute to a better understanding of t

关键词： chronic spinal cord compression compressive cervical myelopathy ferroptosis genome-wide transcriptome glutathione peroxidase 4(GPX4) MAF BZIP transcription factor G(MafG) neurological function

NUMERICAL SI MULATION OF MOVING SCOUR BOUNDARY AND TURBULENCE FLOWAROUND SUBMARINE PIPELINES

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Journal of Hydrodynamics 2005年第4期17卷 404-411页

作者： LI yu-cheng LU Lin State Key Laboratory of Coastal and Offshore Engineering Dalian University of Technology Dalian 116024 China

A two dimensional vertical mathematical model is proposed in this paper for simulating the equilibrium profile of local scour around submarine pipelines. The current model is composed of a new k-ε turbulence model, fitting moving boundary with pre-meshed grid lines and incipient criterion of shear stress for sediments. Employing the proposed model, an instance is carried out numerically and compared with experiments. The calculation results agree well with the experiments. It shows that the improved two equation turbulence model, adopted in this paper is appropriate to simulating the turbulent flow ficld around submarine pipelines, fitting moving boundary with pre-mcshed grid lines method is efficient for moving boundary problems in a multiply connected domain and the stability evaluation method for seabed with critical shear stress based on log-wall law is a reliable choice.

关键词： numerical simulation submarine pipeline local scour moving boundary turbulence model

Bulging intervertebral disc:an asymptotic elasticity solution

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Acta Mechanica Sinica 2018年第6期34卷 1167-1173页

作者： yu-cheng Lo Liu Wang Orthopaedic Department Changhua Christian HospitalChanghuaChina Department of Aerospace Engineering and EngineeringMechanics Center for Mechanics of SolidsStructures andMaterialsUniversity of Texas at AustinAustinTX78712USA

A bulging intervertebral disc (IVD) occurs when pressure on a spinal disc damages the once healthy disc,causing it to compress or change its normal *** medicine,most attention has been paid clinically to diagnosis of and treatment for such problems,which little effect has been made to understand such issues from a mechanics perspective,i.e.,the bulging deformation of the soft IVD induced by excessive compressive *** report herein a simple elasticity solution to understand the bulging disc *** simplicity,the soft IVD is modeled as an incompressible circular composite layer consisting of an inner nucleus and outer annulus,sandwiched between two vertebral segments which are much stiffer than the IVD and can be treated as rigid *** adopting any assumptions regarding prescribed displacements or stresses,we obtained the stress and displacement fields within the composite layer when a certain compressive stain is applied via an asymptotic *** asymptotic approach is very simple and accurate enough for prediction of the bugling profile of the *** also performed finite-element modeling (FEM) to validate our solutions;the predicted stress and displacement fields inside the composite are in good agreement with the FEM results.

关键词： Bulging intervertebral disc (IVD) Elastic composite layer Asymptotic solution Finite element method

Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第01期 288-296页

作者： Shuai Liu Wen-Qiang Xu Ying-Tong Di Man-cheng Tang Ding-Kang Chen Ming-Ming Cao Yao-Wen Chang Hong-yu Tang Chun-Mao yuan Jun-Bo Yang Zhi-Li Zuo Han Guo Zi-Fei Xu Ying Zeng yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of Microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

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Structural topology optimization subject to overhang angle constraint with overhang length relaxation in additive manufacturing

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Science China(Technological Sciences) 2022年第6期65卷 1213-1231页

作者： ZHANG KaiQing cheng GengDong WANG yu Department of Engineering Mechanics Dalian University of TechnologyDalian 116023China State Key Laboratory of Structural Analysis for Industrial Equipment Dalian University of TechnologyDalian 116023China

This paper studies additive manufacturing(AM) oriented structural topology optimization(TO).The minimum compliance design subject to overhang angle constraint with overhang length relaxation and horizontal minimum length control is *** the overhang length relaxation allows additional flexibility for AM product design,there have been very limited studies on *** paper elucidates that the overhang angle constraint we proposed can identify the lower boundary element that violates the overhang angle *** advantage of this fact,we achieve the overhang length relaxation by specifying that the volume fraction of the elements that violate the overhang angle constraint in each local area of the design domain is less than a specified upper bound.A formula for estimating the maximum allowable overhang length of this method is proposed and *** horizontal minimum length constraint is also employed in this *** controlling the horizontal length size of the structural member,this constraint together with the overhang angle constraint with overhang length relaxation suppresses the hanging *** gradient-based optimization algorithm method of moving asymptotic(MMA) is used to solve the TO *** examples show the effectiveness of this *** is observed that the new constraint alleviates the main issues of traditional overhang angle constraints,i.e.,gray element issue,stress concentration issue,and shattered structure *** with the strict traditional overhang angle constraint,the new formulation reduces structural compliance.

关键词： topology optimization overhang angle constraint overhang length relaxation design for manufacturability additive manufacturing

Thermal Property Measurements of a Large Prismatic Lithium-ion Battery for Electric Vehicles

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Journal of Thermal Science 2021年第2期30卷 477-492页

作者： cheng Ximing TANG yu WANG Zhenpo National Engineering Lab for Electric Vehicles Department of Vehicular EngineeringBeijing Institute of TechnologyBeijing 100081China

Because of the high cost of measuring the specific heat capacity and the difficulty in measuring the thermal conductivity of prismatic lithium-ion batteries,two devices with a sandwiched core of the sample-electric heating film-sample were designed and developed to measure the thermal properties of the batteries based on Fourier's thermal *** to electrical circuit modeling,two equivalent thermal circuits were constructed to model the heat loss of the self-made devices,one thermal-resistance steady circuit for the purpose of measuring the thermal conductivity,the other thermal-resistance-capacitance dynamic circuit for the purpose of measuring the specific heat *** the analytic method and recursive least squares,the lumped model parameters of these two thermal circuits were extracted to estimate the heat loss and correct the measured values of the self-made *** to the standard values of the reference samples of the glass and steel plates,the measured values were corrected to improve the measurement accuracies beyond 95% through steady thermal-circuit *** to the measured value of the specific heat capacity of the battery sample at 50% state of charge using the calorimeter,the measured value using the self-made device was corrected in order to elevate the measurement accuracy by about 90% through dynamic thermal-circuit *** verified through the experiments,it was reliable,convenient,and low cost for the proposed methodology to measure the thermal properties of prismatic lithium-ion batteries.

关键词： lithium-ion battery specific heat capacity thermal conductivity equivalent thermal circuit measurement