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Studies on Chemical Constituents of Belamcanda Chinensis(L.)DC.(Ⅱ)

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chinese Chemical Letters 1997年第2期8卷 133-134页

作者： Li Xin ZHOU and Mao LIN(Institute of Materia medica.chinese Academy of medica. Sciences,Peking Union medica. College.Beijing, 100050) Institute of Materia medica Chinese Academy of Medical Sciences Peking Union Medical College Beijing 100050 China

Nine compounds were isolated from the acetone soluble fraction of ethanolic extract of the roots of Belamcanda chinensis (L.)DC. The structure of new compound I,named shegansu A,has been established as irigenin-5-O-(6'-O-vanillin acid)-β-D-glucoside(Ⅰ) by the use of spectroscopic evidence (UV, IR. FAB-MS.1HNMR, 13CNMR,1H-13CNMR and NOE difference spectrum) and chemical *** well known compounds were identified as isorhapotigenin (Ⅲ),resveratrol(Ⅳ), P-hydroxy benzoic acid (Ⅴ), iridin (Ⅵ), tectoridin (Ⅶ),tectorigenin(Ⅷ) and daucosterol(Ⅸ). Ⅲ-Ⅸ were isolated from the plant for the first time.

关键词： DC OCH

chinese Expert Consensus on Clinical Application of Oral Ginkgo biloba Preparations (2020)

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chinese Journal of Integrative Medicine 2021年第3期27卷 163-169页

作者： chinese a.socia.ion of Integrative Medicine chinese medica. Doctor a.socia.ion National Clinical Research Center for chinese Medicine Cardiology Cardiovascular Disease Working Group Encephalopathy Disease Working Group China Center for Evidence-Based chinese Medicine CHEN Keji LIU Yue YANG Hua LIU Long-tao FU Chang-geng 不详 Xiyuan Hospital China Academy of Chinese Medical Sciences China Pharmaceutical University

Ginkgo(Ginkgo biloba L.)is aperennial deciduous tree of the Ginkgoaceae family,and its seeds(ginkgo nut)and leaves have high medicinal *** was firstly recorded in Materia medica.in Shaoxin medica.previous texts on Mat... 详细信息

关键词： Clinical listed mostly

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儿童CT检查辐射剂量标准中国专家共识

中华放射学杂志 2024年第2期58卷 158-164页

作者：中华医学会儿科学分会影像学组中华医学会放射学分会儿科学组彭芸李欣邵剑波孙记航不详国家儿童医学中心首都医科大学附属北京儿童医院影像中心北京100045 天津市第二人民医院放射科天津300192 华中科技大学同济医学院附属武汉儿童医院、武汉市妇幼保健院影像中心、武汉市儿童影像医学临床医学研究中心武汉430015 首都医科大学附属北京儿童医院影像中心

CT是临床常用的检查手段, 儿童生长速度快, 细胞分裂旺盛, X线会对儿童造成更严重的电离辐射损伤, 如何在保证CT诊断的同时减少辐射剂量是儿童影像学的重点问题之一, 但是目前国内尚无统一的儿童CT辐射剂量标准。为进一步规范儿童CT检... 详细信息

CT是临床常用的检查手段, 儿童生长速度快, 细胞分裂旺盛, X线会对儿童造成更严重的电离辐射损伤, 如何在保证CT诊断的同时减少辐射剂量是儿童影像学的重点问题之一, 但是目前国内尚无统一的儿童CT辐射剂量标准。为进一步规范儿童CT检查辐射剂量使用方法, 在满足临床诊断的同时减少儿童所受的电离辐射损伤, 中华医学会儿科学分会影像学组、中华医学会放射学分会儿科学组牵头组织国内相关专家, 结合国内外专家共识和参考文献, 经多次讨论, 对儿童头颅平扫、鼻窦平扫、颞部平扫、颈部平扫、胸部平扫、腹部平扫、头颅增强、胸部增强、腹部增强的辐射剂量标准达成共识, 旨在规范儿童CT检查的辐射剂量, 更好地为儿童的健康安全服务。

关键词：体层摄影术,X线计算机儿童辐射剂量

Huperzine H, a New Lycopodium Alkaloid from Huperzia serrata

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chinese Chemical Letters 1999年第6期10卷 463-466页

作者： Wen Yun GAO Yi M lug LI Bac De WANG Da Yuan ZHU(State Key Laboratory of New Drug Research. Shanghai Institute of Materia medica. chineseAcademy of Sciences, Shanghai 200031) State Key Laboratory of New Drug Research Shanghai Institute of Materia Medica Chinese Academy of Sciences

A new lycopodium alkaloid with a novel skeleton was isolated from Huperzia serrata. Its structure was determined on the basis of spectral evidences.

关键词： Huperzia serrata (Thunb.) Trev. huperzine H isolation structure

Photosynthesis of Tetrahydroprotoberberines with Electron withdrawing Groups on Ring D

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chinese Chemical Letters 1998年第8期9卷 707-710页

作者： Yong Zhou HU Qi Ting ZHOU Dong Lu BAI(Shanghai Institute of Materia medica.chinese Academy of Sciences, 294 Taiyuan Road Shanghai 200031) Shanghai Institute of Materia medica Chinese Academy of Sciences 294 Taiyuan Road Shanghai 200031 China

A number of tetrahydroprotoberberines with electron-withdrawing groups on ring D have been synthesized via photocyclization of 2-formyl-1-benzylideneisoquinorine enamides as the key step.

关键词： photosynthesis tetrahydroprotoberberines

中国政治经济学年度发展报告（2023）（下）

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政治经济学评论 2024年第3期 90+207-208页

作者： Center for Studies of Contemporary Political Economy,Research Institute for 21st-Century Marxism,Nankai University·University of chinese Academy of social Science Center for Teaching and Research on Capital,Renmin University of China National Institute of socialist Political Economy with chinese Characteristics,Renmin University of China 南开大学·中国社会科学院大学21世纪马克思主义研究院当代政治经济学研究中心中国人民大学《资本论》教学与研究中心中国人民大学全国中国特色社会主义政治经济学研究中心

编者按2023年，高质量发展扎实推进，新质生产力加快形成，我国经济总体回升向好，圆满实现发展主要预期目标。为针对性地破解经济恢复发展中的难题，聚焦推进中国式现代化进程中的重点、难点问题，中国政治经济学界开展系统深入研究，...

编者按2023年，高质量发展扎实推进，新质生产力加快形成，我国经济总体回升向好，圆满实现发展主要预期目标。为针对性地破解经济恢复发展中的难题，聚焦推进中国式现代化进程中的重点、难点问题，中国政治经济学界开展系统深入研究，取得系列代表性成果。为准确刻画学界研究进展和轨迹，推动中国经济学理论体系的构建和完善，本刊精选议题如期奉上《中国政治经济学年度发展报告（2023）》。自2010年起，本刊连续十四年发布《中国政治经济学年度发展报告》，“年度发展报告”专栏已成为本刊标志性特色栏目。2023年报告聚焦12个专题，分为（上）（下）两篇，其中专题1—6于报告（上）篇刊登，专题7—12由报告（下）篇刊登。2023年报告（下）选题如下：

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Synthesis of three new Schizandrin Analogues

同方期刊数据库人大复印报刊资料评论

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chinese Chemical Letters 1998年第7期9卷 631-634页

作者： Lan XIE Jing Xi XIE(Institute of Materia medica. chinese Academy of medica. Sciences 1 Xian Nong Tan Street, Beijing 100050) Institute of Materia medica Chinese Academy of Medical Sciences 1 Xian Nong Tan Street Beijing 100050 China

Three new Schizandrin analogues with dibenzocycloheptatriene skeletons have been synthesized. Their structures were identified by MS, UV, IR and NMR spectral data.

关键词： schizandrin analogues

chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)

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Frontiers of Medicine 2022年第5期16卷 815-826页

作者： Suning Chen Weili Zhao Jianyong Li Depei Wu on behalf of Lymphoid Disease Group,chinese Society of Hematology,chinese medica. a.socia.ion National Clinical Research Center for Hematologic Diseases Suzhou 215006China Jiangsu Institute of Hematology the First Affiliated Hospital of Soochow UniversitySuzhou 215006China Shanghai Institute of Hematology State Key Laboratory of Medical GenomicsNational Research Center for Translational Medicine at ShanghaiRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200025China Department of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalCollaborative Innovation Center for Cancer Personalized MedicineNanjing 210029China

Oral drugs such as ibrutinib play an important role in the treatment of mature B-cell lymphoma(BCL)due to their reliable efficacy,manageable safety,high accessibility,and convenience for ***,no guidelines or consensus focusing on oral drug therapies for BCL is *** provide a reference of oral agent-based treatment for mature BCL,a panel of experts from the Lymphocyte Disease Group,chinese Society of Hematology,chinese medica. a.socia.ion conducted an extensive discussion and reached a consensus on oral drugs for chinese BCL patients on the basis of the current application status of oral drugs in China,combined with the latest authoritative guidelines in the world and current research *** consensus reviewed the application of oral drugs in the treatment of BCL and the latest research and provided appropriate recommendations on the use of oral drugs for indolent or aggressive BCL *** the deepening of research and the development of standardized clinical applications,oral medica.ions will bring better treatment to BCL patients,enabling more patients to benefit from them.

关键词： B-cell lymphoma oral drug targeted therapy immunotherapy COVID-19 pandemic

Serine racemase expression in mouse cerebral cortex after permanent focal cerebral ischemia

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Acta Pharmacologica Sinica 2004年第4期25卷 38-43页

作者： Li-zhenWANG, Xing-zu ZHU2 Department of Pharmacology, Shanghai Institute of Materia medica. Shanghai Institutes for Biological Sciences, chinese Academy of Sciences, Shanghai 201203, China Department of Pharmacology Shanghai Institute of Materia MedicaShanghai Institutes for Biological Sciences Chinese Academy of Sciences

AIM: To study the alterations of the expressions of serine racemase in C57BL/6 mouse brain after permanent focal cerebral ischemia. METHODS: The mRNA level and the protein level of serine racemase were assayed by semiquantitative reverse transcription polymerase chain reaction (RT-PCR) and Western blot, respectively. The amount of D-serine and L-serine were measured by HPLC. RESULTS: High levels of serine racemase were constitutively expressed in the normal cortex of mouse. At early stage after middle cerebral artery occlusion (MCAO), no significant change in expression of serine racemase was observed in temporoparietal cortex in ipsila- teral hemisphere. However, delayed transient decreases of serine racemase in both mRNA and protein levels were detected from d 6 to d 10 after ischemia. Correspondingly, D-serine concentration also declined in the ipsilateral cortex during this period when compared with the D-serine level in the contralateral cortex. CONCLUSion: Delayed decreases in serine racemase expression and D-serine level occurred in the temporoparietal cortex at the late stage after focal cerebral ischemia.

关键词： D-serine L-serine serine racemase inbred C57BL mice brain ischemia