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Evidence-based expert consensus on clinical management of safety of Bruton’s tyrosine kinase inhibitors(2024)

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chinese Journal of Cancer Research 2024年第3期36卷 240-256页

作者： Zaiwei Song Dan Jiang Lingling Yu Yixuan Chen Daobin Zhou Yue Li Depei Wu Lingli Zhang Liyan Miao Jun Ma Jun Zhu Hongmei Jing Rongsheng Zhao the Steering Committee,the Consensus Panel and the Evidence Synthesis Group Evidence-based Pharmacy Professional Committee of chinese Pharmaceutical a.socia.ion(CPA) Hospital Pharmacy Professional Committee of chinese Pharmaceutical a.socia.ion(CPA) Division of Therapeutic Drug Monitoring of chinese Pharmacological Society(CPS) Expert Committee on Lymphoma of chinese Society of Clinical Oncology(CSCO) Expert Committee on Leukemia of chinese Society of Clinical Oncology(CSCO) Society of Integrative Cardio-Oncology of China Anti-Cancer a.socia.ion(CACA) chinese Society of Hematology of chinese medica. a.socia.ion(CMA) Hospital Pharmacy Professional Committee of Cross-Straits Medicine Exchange a.socia.ion(SMEA) Department of Pharmacy Peking University Third HospitalBeijing 100191China Institute for Drug Evaluation Peking University Health Science CenterBeijing 100191China Therapeutic Drug Monitoring and Clinical Toxicology Center Peking UniversityBeijing 100191China Department of Pharmacy Administration and Clinical Pharmacy School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Department of Hematology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100005China Department of Cardiology the First Affiliated HospitalHarbin Medical UniversityHarbin 150001China Department of Hematology the First Affiliated Hospital of Soochow UniversitySuzhou 215006China Department of Pharmacy Evidence-based Pharmacy CenterWest China Second HospitalSichuan UniversityChengdu 610041China Department of Pharmacy the First Affiliated Hospital of Soochow UniversitySuzhou 215006China Department of Hematology and Oncology Harbin Institute of Hematology and OncologyHarbin 150010China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of LymphomaPeking University Cancer Hospital&InstituteBeijing 100142China Department of Hematology Peking University Third HospitalBeijing 100191China 不详

Bruton’s tyrosine kinase inhibitors(BTKis)have revolutionized the treatment of B-cell ***,safety issues related to the use of BTKis may hinder treatment continuity and further affect clinical efficacy.A comprehensive and systematic expert consensus from a pharmacological perspective is lacking for safety issues associated with BTKi treatment.A multidisciplinary consensus working group was established,comprising 35 members from the fields of hematology,cardiovascular disease,cardio-oncology,clinical pharmacy,and evidencebased *** evidence-based expert consensus was formulated using an evidence-based approach and the Delphi *** Joanna Briggs Institute Critical Appraisal(JBI)tool and Grading of Recommendations Assessment,Development,and Evaluation(GRADE)approach were used to rate the quality of evidence and grade the strength of recommendations,*** consensus provides practical recommendations for BTKis medica.ion based on nine aspects within three domains,including the management of common adverse drug events such as bleeding,cardiovascular events,and hematological toxicity,as well as the management of drug-drug interactions and guidance for special *** multidisciplinary expert consensus could contribute to promoting a multi-dimensional,comprehensive and standardized management of BTKis.

关键词： Consensus BTK inhibitors safety adverse drug events drug-drug interactions

Meet Our New Associate Editors

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chinese Journal of Chemistry 2024年第11期42卷 1319-1321页

作者： Editorial Office of chinese Journal of Chemistry 不详

Associate Editor Dehui Deng Professor The State Key Laboratory of Catalysis Dalian Institute of Chemical Physics,chinese Academy of Sciences,China(+86)0411-82463870,dhdeng@***,https:/***/.Education:2003-2007 B.S.,Light Industry Engineering and National Economy Management,Sichuan University.2007-2013 Ph.D.,Physical Chemistry,Dalian Institute of Chemical Physics,chinese Academy of Sciences(Supervisor:*** Bao and *** Pan).

关键词： Dalian Economy Associate

Meet Our New Editorial Board Members of Spotlights

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chinese Journal of Chemistry 2024年第16期42卷 1932-1936页

作者： Editorial Office of chinese Journal of Chemistry 不详

Editorial Board Member of *** ***,College of Materials Science and Engineering Beijing University of Chemical ***:2006-2010,B.S.,Materials Science and Engineering,Beijing University of Chemical Technology.2010-2015,Ph... 详细信息

关键词： Spotlight Editorial Board

Transarterial chemoembolization refractoriness in hepatocellular carcinoma: chinese College of Interventionalists definition and consensus statement

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中华医学杂志(英文版) 2024年第17期137卷 2040-2042页

作者： Zhong Binyan Zhang Shen Zhu Haidong Wang Wansheng Ni Caifang Clinical Guidelines Committee of chinese College of Interventionalists Department of Interventional Radiology The First Affiliated Hospital of Soochow University Suzhou Jiangsu China Center of Interventional Radiology & Vascular Surgery Department of Radiology Zhongda Hospital Medical School Southeast University Nanjing Jiangsu China

Stress Echocardiography for Chronic Coronary Syndrome:Clinical Practice Guidelines(2023)

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Journal of Geriatric Cardiology 2024年第5期21卷 475-505页

作者： Peng-Fei ZHANG Jia-Wei TIAN Tian-Gang ZHU Jue-Fei WU Xiao-Ping LENG Yi WANG Meng-Meng LI Xin-Hao LI Qian-Qian WANG Xiao-Peng FENG Jia-Yan LV Li-Xue YIN Yun ZHANG Mei ZHANG chinese Society of Echocardiography,Superficial Tissue and Vascular Group of chinese Society of Ultrasound in Medicine,Ultrasound Professional Committee of chinese Medicine Education a.socia.ion State Key Laboratory for Innovation and Transformation of Luobing Theory Key Laboratory of Cardiovascular Remodeling and Function ResearchChinese Ministry of EducationChinese National Health Commission and Chinese Academy of Medical SciencesDepartment of CardiologyQilu Hospital of Shandong UniversityJinanChina The Second Affiliated Hospital of Harbin medica. University HaerbinChina Peking University People's Hospital BeijingChina Sichuan Province People's Hospital ChengduChina Nanfang Hospital Southern Medical UniversityGuangzhouChina Peking Union medica. College Hospital Chinese Academy of Medical SciencesBeijingChina 不详

In the context of the People's Republic of China,coronary artery disease(CAD)presents a sig-nificant clinical challenge,with over 11.3 mil-lion patients ***,the diagnos-is of CAD has predominantly relied on invasive coronary angiography.[1]However,recent advances in clinical research have revealed a notable trend:a substantial 82% of patients subjected to such invas-ive diagnostics do not necessitate interventional therapy.

关键词： coronary clinical patients

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Guide for Authors

chinese Journal of Aeronautics 2024年第6期37卷 F0003-F0003页

作者： Editorial Office of chinese Journal of Aeronautics Editorial Office of chinese Journal of Aeronautics 2024

About Journal chinese Journal of Aeronautics (CJA) is a comprehensive academic journal dealing with the fields of aeronautics and *** reports researches concerning the two fields in China and abroad to promote the academic *** in 1988 and sponsored by the chinese Society of Aeronautics and Astronautics and Beihang University,CJA publishes papers *** intended readers of the journal are specialized technical workers,teachers and students in colleges and universities and the related personnel of management,and they devote themselves to or are interested in the scientific research,teaching,design,experimentation,manufacture or application in the industries of aeronautics and astronautics.

关键词： dealing concerning exchange

Animal models of hepatitis E infection: Advances and challenges

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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 171-180页

作者： Ze Xiang Xiang-Lin He Chuan-Wu Zhu Jia-Jia Yang Lan Huang Chun Jiang Jian Wu chinese Consortium for the Study of Hepatitis E(CCSHE) Zhejiang University School of Medicine Hangzhou 310030China Department of Infectious Diseases The Fifth People’s Hospital of SuzhouSuzhou 215007China Department of Infection Management The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu SchoolNanjing Medical UniversitySuzhou 215008China Department of Clinical Laboratory The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu SchoolNanjing Medical UniversitySuzhou 215008China 不详

Hepatitis E virus(HEV)is one of the leading causes of acute viral hepatitis *** most of HEV infections are asymptomatic,some patients will develop the symptoms,especially pregnant women,the elderly,and patients with preexisting liver diseases,who often experience anorexia,nausea,vom-iting,malaise,abdominal pain,and *** infection may become chronic in immunosuppressed *** addition,HEV infection can also cause several extrahepatic *** exists in a wide range of hosts in nature and can be transmitted across ***,animals susceptible to HEV can be used as *** establishment of animal models is of great significance for studying HEV transmission,clinical symptoms,extrahepatic manifestations,and therapeutic strategies,which will help us understand the pathogenesis,prevention,and treatment of hepatitis *** review summarized the animal models of HEV,including pigs,monkeys,rabbits,mice,rats,and other *** each animal species,we provided a concise summary of the HEV genotypes that they can be infected with,the cross-species transmission pathways,as well as their role in studying extrahepatic manifestations,prevention,and treatment of HEV *** advantages and disadvantages of these animal models were also *** review offers new perspectives to enhance the current understanding of the research landscape surrounding HEV animal models.

关键词： Hepatitis E virus Animal models Pathogenesis Prevention Treatment

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香芍颗粒临床应用专家共识

中国中药杂志 2024年第18期49卷 5069-5075页

作者： China a.socia.ion of chinese Medicine 中华中医药学会

香芍颗粒临床广泛用于经前期紧张综合征与更年期综合征的治疗，但目前尚未形成基于循证医学的指南及共识，为规范临床医师合理用药，最大程度发挥使用价值，制定该共识。共识以临床问题为导向，遵循“循证为主、共识为辅”的原则，客观... 详细信息

香芍颗粒临床广泛用于经前期紧张综合征与更年期综合征的治疗，但目前尚未形成基于循证医学的指南及共识，为规范临床医师合理用药，最大程度发挥使用价值，制定该共识。共识以临床问题为导向，遵循“循证为主、共识为辅”的原则，客观评价香芍颗粒诊治疾病的证据，经专家充分论证后形成。该共识由全国29家三级甲等医院，3所省属中医院校的多学科专家共同参与完成，其中中医专家16位，西医专家13位，中西医结合专家2位，药学专家1位，循证医学专家2位。项目于2021年8月于中华中医药学会申请立项(202108050-GS-CACM),编制过程历时2年，于2023年11月29日发布(GS/CACM 334-2023)。该文详细介绍了共识的立项背景，阐述了立项、构建共识问题、形成推荐意见及共识建议、起草、形成专家共识、征求意见等编制过程，明确了香芍颗粒临床应用的适应证、给药方案与时机、剂量、疗程、安全性、注意事项等关键性问题，以指导临床医生规范、合理用药。

关键词：香芍颗粒更年期综合征经前期紧张综合征推荐意见共识建议编制说明

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chinese Society of Cardiology guidelines on the diagnosis and treatment of adult fulminant myocarditis

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Science China(Life Sciences) 2024年第5期67卷 913-939页

作者： chinese Society of Cardiology,chinese medica. a.socia.ion,Writing Group Jiangang Jiang Hongyang Shu Dao Wen Wang Rutai Hui Chenze Li Xiao Ran Hong Wang Jing Zhang Shaoping Nie Guanglin Cui Dingcheng Xiang Qun Shao Shengyong Xu Discussion experts:Ning Zhou Yuming Li Wei Gao Yuguo Chen Yuan Bian Guoping Wang Liming Xia Yan Wang Chunxia Zhao Zhiren Zhang Yuhua Zhao Jianan Wang Shaoliang Chen Hong Jiang Jing Chen Xianjin Du Mao Chen Yinxian Sun Sheng Li Hu Ding Xueping Ma Hesong Zeng Li Lin Shenghua Zhou Likun Ma Ling Tao Juan Chen Yiwu Zhou Xiaomei Guo 不详 Tongji Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Fuwai Hospital National Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China Zhongnan Hospital of Wuhan University Wuhan 430062China Fuwai Huazhong Cardiovascular Hospital Zhengzhou 450003China Beijing Anzhen Hospital Capital Medical UniversityBeijing 100029China Guangzhou General Hospital of Guangzhou Military Command Guangzhou 510010China Harbin medica. University Cancer Hospital Harbin 150081China Union Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Taida Hospital Tianjin 300457China Peking University Third Hospital Beijing 100191China Qilu Hospital of Shandong University Jinan 250012China Kanghua Hospital DongguanGuangzhou 523080China Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003China Nanjing First Hospital Nanjing Medical UniversityNanjing 210006China Renmin Hospital of Wuhan University Wuhan 430060Wuhan West China Hospital Sichuan UniversityChengdu 610044China First Hospital of China medica. University Shenyang 110002China General Hospital of Ningxia medica. University Yinchuan 750003China The Second Xiangya Hospital Central South UniversityChangsha 410012China The First Affiliated Hospital of USTC University of Science and Technology of ChinaHefei 230002China The First Affiliated Hospital of Air Force medica. University Xi’an 710032China Central Hospital of Wuhan City Wuhan 430014China Tongji medica. College Huazhong University of Science and TechnologyWuhan 430030China

Fulminant myocarditis is an acute diffuse inflammatory disease of *** is characterized by acute onset,rapid progress and high risk of *** pathogenesis involves excessive immune activation of the innate immune system and formation of inflammatory *** to China’s practical experience,the adoption of the“life support-based comprehensive treatment regimen”(with mechanical circulation support and immunomodulation therapy as the core)can significantly improve the survival rate and long-term *** emphasis is placed on very early identification,very early diagnosis,very early prediction and very early treatment.

关键词： fulminant myocarditis guidelines life support-based comprehensive treatment regimen diagnosis treatment cytokine storm overactivation of immunity