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Adjuvant hepatic chemotherapy after resection of solitary hepatocellular carcinoma associated with hepatitis B virus cirrhosis

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Hepatobiliary & Pancreatic Diseases International 2006年第2期5卷 224-227页

作者： Jun Wen, Wen-Lv Shen and Shao-Hua Yang Department of Surgery, Second Hospital of Shantou University of Medical college, Shantou 515041 , china Department of Surgery Second Hospital of Shantou University of Medical College Shantou 515041 China. wenjun115@***

BACKGROUND: Although resection is the major treatment for patients with hepatocellular carcinoma ( HCC), the high intrahepatic recurrence remains a cardinal cause of death. This study was undertaken to evaluate the effect of hepatic arterial infusion chemotherapy on the survival and recurrence of HCC patients with hepatitis B virus ( HBV) cirrhosis after resection. METHODS: Twenty-eight patients who had undergone placement of a hepatic arterial pump at the time of liver wedge resection for HCC from 1998 through 2004 were reviewed retrospectively. These patients aged 23-71 years had HBV cirrhosis (Child-Pugh class A or B). They were given floxuridine(FUDR) (250 mg), doxorubicin (10 mg) and mitomycin C (4 mg) alternatively every 2 or 3 days through arterial pumps for 8 cycles each year in the first two years after resection. Meanwhile, traditional Chinese herbal medicine was prescribed to the patients. When the leucocyte count was as low as 3 x 109/L or asparate aminotransferase (AST) level was significantly increased, the regimen of chemotherapy was delayed for the normalization of leucocyte count and AST level (below 80 U/L). RESULTS: Of the 28 patients, 23 received 8 or 16 cycles of the set regimen of chemotherapy. These patients are alive with no evidence of recurrence. Among them, 5,7, and 11 patients are alive beyond 5 years, 3 years, and 1 year respectively. In the remaining 5 patients, 3 who had had a HCC 10 cm or more in diameter showed tumor recurrence within 1 year, in whom, 8 cycles of chemotherapy were not completed because of their low leucocyte count (<3 × 109/L) and poor liver function. One patient who had received 8 cycles of chemotherapy demonstrated recurrence at 16 months after resection. One patient who had received 16 cycles of chemotherapy had intrahepatic recurrence at 58 months after surgery. No recurrence was observed in 17 patients who had received 16 cycles of chemotherapy. CONCLUSION: Adjuvant hepatic arterial chemotherapy may be feasible

关键词： carcinoma, hepatocellular hepatitis B virus cirrhosis resection chemotherapy

Comparative Study on Fractal Dimension Property of 40Hz Event-Related Potentials Under Various Cognitive Tasks Loading Conditions

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Chinese Journal of Biomedical Engineering 2000年第3期 135-140页

作者： ZHANG Zuo sheng 1,PENG Hu 1,WEI Yong mei 2[WT4”BZ] 1.Institute of Biomedical Engineering of USTC,Hefei 230026,china 2.Physics Department of Fuyang Teachers college[WT5HZ]

The fractal dimension property of 40Hz event related potentials(ERPS) is studied for tests of Chinese word short term memory recognition, mental arithmetic calculation and short term memory capacity. By comparison it is found that there is a remarkable difference in the fractal dimensions of 40Hz ERPS for different cognitive tasks. Meanwhile, for the identical cognitive process, there is a distinct hemispheric difference in fractal dimension property of 40Hz ERPS, which indicates that there exists a noticeable difference in the property of brain dynamical between the two hemispheres under different cognitive tasks.

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Model and Solution for Capacitated Facility Location Problem

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Model and Solution for Capacitated Facility Location Problem

第24届中国控制与决策会议

作者： Hongtao Yu 1,2 , Liqun Gao 2 , Yanhua Lei 1 1. Automation Engineering, Shenyang Institute of Engineering, Shenyang 110136, china 2. college of Information Science and Engineering, Northeastern University, Shenyang 110819, china

This paper presents a new model for capacitated facility location problem, where serve radius and economic benefit are considered. In the new model, the objective is to maximize the total return investment. However, the objective for multiple knapsack problem is to maximize the total profit. So the capacitated facility location problem can be translated into multiple knapsack problem. Because this problem is difficult to solve, we propose a hybrid harmony search algorithm, which incorporates harmony search algorithm with greedy algorithm. Numerical results from computational experiments are presented and analyzed.

关键词： Harmony search algorithm Capacitated Facility location Knapsack problem

Analysis of Genetic Diversity and Phylogenetic Relationship of Ricinus communis Germplasm by SRAP Markers

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Analysis of Genetic Diversity and Phylogenetic Relationship ...

2009整合植物生物学研讨会

作者： Lu Zheng~1,Jianmin Qi~(2*),Pingping Fang~2,Jianguang Su~3,Jiantang Xu~2 and Aifen Tao~2 1 Fujian Institue of TCM,Fuzhou 350003,china 2 college of Crops Sciences/Life Sciences,Fujian Agriculture and Forestry University, Fuzhou 350002,china 3 Institute of Bast Fiber Crops,Chinese Academy of Agricultural Sciences,Changsha 410006,china.

Castor(Ricinus communis L.)is an important oil *** 20 SRAP primers,263 bands were amplified in 81 *** varieties;among them 214 bands(81.37%)were *** genetic similarity coefficients of 81 materials ranged from 0.32558 to

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土壤磷素分级方法研究评述

土壤通报 2003年第3期34卷 229-232页

作者：胡佩周顺桂刘德辉四川师范大学化学与生命科学学院四川成都61066 南京农业大学资源与环境科学学院江苏南京210095

讨论了土壤磷素形态和有机磷有效性研究进展,分析了传统土壤磷素分级方法局限性,综述了土壤磷素分级方法的研究进展,特别详细地描述了Hedley法和Guppy法。

关键词：土壤磷素分级方法 Hedley法 Guppy法

Research on Comprehensive Safety Assessment Method for Wheel Loader Based on Analytic Hierarchy Process and Fuzzy Mathematics

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Research on Comprehensive Safety Assessment Method for Wheel...

2009年工程机械与车辆工程新进展国际学术会议

作者： Fan Ying~1 Tian Zhicheng~2 Cong Guoquan~2 Xia Mingzhu~2 1.college of Mechanical and Electrical Engineering Taiyuan University of Science and Technology Taiyuan 030024 P.R.china 2.china National Construction Machinery Quality Supervising Test Centre Beijing 102100 P.R china

＜正＞Since wheel loaders had been widely used and frequent accidents had been focused great attention to,it is highly essential to conduct a research on the *** the present article,based on the wheel loader accident investigation and failure analysis,the risk factors were studied through risk analysis method, and the wheel loader safety evaluation system was established. Combining fuzzy evaluation theory with Analytical rarchy Process（AHP）,the comprehensive evaluation Hiemodel for wheel loader safety was *** examples had proved the feasibility of the system,and the draft of the safety evaluation regulation of wheel loader had been finally formed.

关键词： Wheel loader,Risk analysis AHP Fuzzy evaluation theory

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美国教师专业化发展的特质

外国教育研究 2007年第9期34卷 77-80页

作者：郭臻琦孙英李克军邢台学院院长办公室河北邢台054001 河北大学外语学院河北保定071002 承德民族师范高等专科学校校长办公室河北承德067000

美国教师专业化在经历了二三十年的变革与发展之后,其框架体系已基本成熟,显示出了重视教师教育专业课程建设、倡导"反思经验"实践、严格教师资格认可制度的基本取向,呈现了师资水平的高学历化、培养培训的多样化、教师活动的组织化等... 详细信息

美国教师专业化在经历了二三十年的变革与发展之后,其框架体系已基本成熟,显示出了重视教师教育专业课程建设、倡导"反思经验"实践、严格教师资格认可制度的基本取向,呈现了师资水平的高学历化、培养培训的多样化、教师活动的组织化等主要特点,并推动了美国乃至世界各国教师专业化的深入发展。

关键词：美国教师教育教师专业化基本取向主要特点

An Engineering Design of a 2MW Direct-drive Permanent-magnet Wind-power Generation System

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An Engineering Design of a 2MW Direct-drive Permanent-magnet...

第11届国际电机与系统学术会议

作者： Shoudao Huang~1 Xin Long~2 Luoqiang Cai~2 Keyuan Huang~1 and Jian Gao~1 1 college of Electrical &Information Engineering Hunan University Changsha china 410082 2 Xiangtan Electrical Machine Ltd.Co. Xiangtan china 413200

＜正＞With rapid development of the power semiconductor devices,direct-drive permanent magnet synchronous generator （PMSG） has shown the significant advantages for its high efficiency,reliability,and becomes an attractive choice for variable-speed wind power generation,MW class PMSG system with larger capacity,higher power density is an important trend. This paper describes the engineering design of the domestic first 2MW direct-drive PMSG system,including optimal machine design,converter topology choosing and its *** generator injects the power to the grid through two fully controlled back-to-back PWM converters that are parallel connected as master-slave structure.A load current sharing control strategy is presented for the parallel *** experimental results are given to illustrate the performance of the actual system.

关键词： direct-drive PMSG engineering design back-toback converter parallel connection

Combined effects of ramipril and angiotensin Ⅱ receptor blocker TCV116 on rat congestive heart failure after myocardial infarction

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中华医学杂志(英文版) 2005年第2期000卷 60-68页

作者： TAO Ze wei, HUANG Yuan wei, XIA Qiang and XU Qi wen Department of Cardiology, Chinese People Armed Police Force Hospital of Hunan Province, Changsha 410006, china Department of Cardiology, First Affiliated Hospital, college of Medicine, Zhejiang University, Hangzhou 310003, china Department of Physiology, college of Medicine, Zhejiang University, Hangzhou 310006, china Department of Cardiology Chinese People Armed Police Force Hospital of Hunan Province Changsha 410006 China Department of Cardiology First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China Department of Physiology College of Medicine Zhejiang University Hangzhou 310006 China

Background Congestive heart failure (CHF) is a major cause of morbidity and mortality worldwide and angiotensin convertingenzyme inhibitor (ACEI) is the cornerstone in its treatment However, CHF continues to progress despite this therapy, perhaps because of production of angiotensin Ⅱ (Ang Ⅱ) by alternative pathways The present study was conducted to examine the combined effects of a chronic ACEI, ramipril, and a chronic Ang Ⅱ type 1 receptor blocker, TCV116, on rat CHF after myocardial infarction (MI) Methods Congestive heart failure was caused by MI in rats, which was induced by ligating the left anterior descending coronary artery The experiment protocol included shamoperated rats (Sham), MIcontrol rats (MIcontrol), MI rats treated with ramipril 3 mg/kg (MIramipril) or TCV116 2 mg/kg (MITCV116) per day, half dosage (MI1/2R&T) or full dosage (MIR&T) combination of the two At 22 weeks, cardiac hemodynamic parameters such as mean arterial pressure (MAP), left ventricular systolic pressure (LVSP), maximal rate of left ventricule pressure development and decline (LV dP/dtmax) and left ventricular end diastolic pressure (LVEDP), and cardiac morphometric parameters such as heart weight (HW), left ventricular weight (LVW) and left ventricular cavity area (LVCA) were measured, mRNA expressions of cardiac molecule genes such as β myosin heavy chain (βMHC), Btype natriuretic peptide (BNP), transforming growth factorβ1 (TGFβ1), collagen I and Ⅲ were quantified with reverse transcription polymerase chain reaction (RTPCR) in the surviving septum myocardium, and survival rates were calculated Results There were no significant differences in MI sizes (%) among each MI related experimental groups (33±13, 34±14, 33±13, 35±13 and 33±14 for MIcontrol, MIramipril, MITCV116, MI1/2R&T and MIR&T, respectively, no statistical significance for all) Compared with shamoperated rats, MI rats without therapy showed significant increases in morphometric paramete

关键词： renin angiotensin aldosterone system · angiotensin Ⅱ · myocardial infarction · ventricular remodeling · congestive heart failure