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创设探究式实验情境构建深度学习型课堂

物理通报 2024年第3期 34-37页

作者：王驰明西安交通大学苏州附属中学江苏苏州215000

以“曲线运动”为例基于深度学习理念,有效关注知识的建构生成过程,重视思维训练,促进学生思维成长,让物理学科核心素养真正地在课堂教学中落地.

关键词：深度学习学科素养情境体验科学探究

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加强城市全生命周期管理的思考和建议

城市管理与科技 2024年第1期25卷 13-15页

作者：余池明全国市长研修学院(住房和城乡建设部干部学院)城市发展研究所

全生命周期管理是基于系统科学的现代管理理念和方法。把全生命周期管理理念贯穿城市规划、建设、管理全过程各环节,对提高城市治理水平具有重要意义。贯彻全生命周期管理理念,首先要建立健全科学的全生命周期管理体制机制,其次要构建... 详细信息

全生命周期管理是基于系统科学的现代管理理念和方法。把全生命周期管理理念贯穿城市规划、建设、管理全过程各环节,对提高城市治理水平具有重要意义。贯彻全生命周期管理理念,首先要建立健全科学的全生命周期管理体制机制,其次要构建智能化的全生命周期监管平台,通过全生命周期管理提高城市基础设施投资、建设、运行维护的效能和安全性。

关键词：全生命周期管理现代管理理念城市规划监管平台思考和建议运行维护智能化体制机制

银连含漱液防治鼻咽癌放疗后急性放射性口咽黏膜炎的临床疗效观察

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中药新药与临床药理 2024年第1期35卷 141-147页

作者：方彩珊肖佩琪钟毓汪咏春张驰名周敏闫亚杰阮岩广州中医药大学第一临床医学院广东广州510405 成都中医药大学附属医院四川成都610000 广州中医药大学第一附属医院广东广州510405 中山大学附属第三医院过敏科广东广州510630 广东省中医临床研究院岭南耳鼻喉病研究所广东广州510405

目的观察银连含漱液防治鼻咽癌放疗引起的急性放射性口咽黏膜炎的临床疗效。方法将32例初次行放疗的鼻咽癌患者随机分为试验组(19例)和对照组(13例),两组在放疗、化疗的基础上,试验组予银连含漱液漱口,对照组予生理盐水漱口。观察两组... 详细信息

目的观察银连含漱液防治鼻咽癌放疗引起的急性放射性口咽黏膜炎的临床疗效。方法将32例初次行放疗的鼻咽癌患者随机分为试验组(19例)和对照组(13例),两组在放疗、化疗的基础上,试验组予银连含漱液漱口,对照组予生理盐水漱口。观察两组患者干预前后严重急性放射性口咽黏膜炎的发生率,出现口咽部不适、口咽部疼痛的时间和程度(NRS评分)、生活质量评分(QOL-NPC评分)、出现放疗毒副作用(SE-QOLNPC评分)及口干症状(SE1评分)的时间及程度。结果放疗至第6周时,试验组Ⅲ级及以上的放射性口咽黏膜炎的发生率显著低于对照组(P<0.001);放疗结束后1个月,试验组I级及以上的放射性口咽黏膜炎的发生率显著低于对照组(P<0.001)。从放疗第2周开始,试验组咽部不适NRS评分低于对照组(P<0.05);从放疗第4周开始口腔及口咽部疼痛NRS评分低于对照组(P<0.05);从放疗第5周开始试验组SE1评分高于对照组(P<0.05);在放疗结束后1个月,试验组咽部不适NRS评分、口腔及口咽部疼痛NRS评分低于对照组(P<0.001),QOL-NPC评分、SE-QOL-NPC评分和SE1评分均高于对照组(P=0.05或P<0.05)。结论鼻咽癌患者在放疗期间使用银连含漱液,可以显著减少严重的急性放射性口咽黏膜炎的发生,有效延迟和缓解急性放射性口咽黏膜炎的相关症状,提高患者放疗期间的生活质量,且在放疗结束1个月后,对急性放射性口咽黏膜炎仍有较好的疗效。

关键词：银连含漱液鼻咽癌急性放射性口咽黏膜炎临床疗效

关于打造乡村旅游民宿集聚区的调查与思考——以南京市浦口区为例

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中共乌鲁木齐市委党校学报 2024年第2期 72-76页

作者：修楠张弛明中共南京市浦口区委员会党校江苏南京211800

作为一种新场景和新业态,乡村旅游民宿业是拉长旅游消费链条,提升乡村旅游美誉度的重要环节,在拉动居民消费、增加农民收入方面的作用明显。通过调查分析南京市浦口区围绕创建“国家全域旅游示范区”,打造乡村旅游民宿集聚区的实践,针... 详细信息

作为一种新场景和新业态,乡村旅游民宿业是拉长旅游消费链条,提升乡村旅游美誉度的重要环节,在拉动居民消费、增加农民收入方面的作用明显。通过调查分析南京市浦口区围绕创建“国家全域旅游示范区”,打造乡村旅游民宿集聚区的实践,针对存在的问题,提出高质量打造乡村旅游民宿集聚区的对策建议,以供相关部门借鉴参考。

关键词：乡村振兴全域旅游民宿集聚区

Primula pengzhouensis (Primulaceae), a new species from Sichuan, southwestern China

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Plant Diversity 2017年第4期39卷 229-231页

作者： Yuan Xu Gehan Huang chiming Hu Gang Hao Guangdong Provincial Key Laboratory of Applied Botany South China Botanical GardenChinese Academy of SciencesGuangzhou 510650China College of Life Sciences South China Agricultural UniversityGuangzhou 510642China

A new species, Primula pengzhouensis(Primulaceae), from central Sichuan, China, is described and illustrated. It is assigned to Primula sect. Aleuritia subsect. Yunnanensis, and is most similar to P. socialis,but can ... 详细信息

关键词： Primula New species Primula pengzhouensis

OsSIDP366,a DUF1644 gene,positively regulates responses to drought and salt stresses in rice

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Journal of Integrative Plant Biology 2016年第5期58卷 492-502页

作者： chiming Guo Chengke Luo Lijia Guo Min Li Xiaoling Guo Yuxia Zhang Liangjiang wang Liang Chen Xiamen Key Laboratory for Plant Genetics School of Life SciencesXiamen UniversityXiamen 361102China College of the Environment and Ecology Xiamen UniversityXiamen 361102China Department of Genetics and Biochemistry Clemson UniversityClemsonSouth Carolina 29634USA.

Domain of unknown function 1644 （DUF1644） is a highly conserved amino acid sequence motif present only in plants. Analysis of expression data of the family of DUF1644- containing genes indicated that they may regulate responses to abiotic stress in rice. Here we present our discovery of the role of Os.SIDP366, a member of the DUF1644 gene family, in response to drought and salinity stresses in rice. Transgenic rice plants overexpressing OsSIDP366 showed enhanced drought and salinity tolerance and reduced water loss as compared to that in the control, whereas plants with downregulated OsSIDP366 expression levels using RNA interference （RNAi） were more sensitive to salinity and drought treatments. The sensitivity to abscisic acid （ABA） treatment was not changed in OsStDP366-overexpressing plants, and OsSIDP366 expression was not affected in ABA- deficient mutants. Subcellular localization analysis revealed that OsSIDP366 is presented in the cytoplasmic foci that colocalized with protein markers for both processing bodies （PBs） and stress granules （SGs） in rice protoplasts. Digital gene expression （DGE） profile analysis indicated that stress-related genes such as SNACl, OsHAK5 and PRs were upregulated in OsSIDP366-overexpressing plants. These results suggest that OsSIDP366 may function as a regulator of the PBs/SGs and positively regulate salt and drought resistance in rice.

关键词： Abiotic stress DUF1644 processing bodies rice stressgranules

Unraveling the Formation Mechanism of Subphthalocyanine.Density Functional Theory Studies

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Unraveling the Formation Mechanism of Subphthalocyanine.Dens...

Room Temperature Chiral Reorganization of Interfacial Assembly

中国化学会第四届卟啉与酞菁学术研讨会

作者： chiming wang Xin Chen Dongdong Qi Siwei Bi Jianzhuang Jiang Beijing Key Laboratory for Science and Application of Functional Molecular and Crystalline Materials Department of ChemistryUniversity of Science and Technology Beijing School of Chemistry and Chemical Engineering Qufu Normal University

A systematic investigation over the formation mechanism of the subphthalocyanine,SubPc（Cl）,with phthalonitrile as the initial reagent mediated by boron trichloride in the solvent of p-xylene has been carried out on the basis of density functional theory,revealing truly a long reaction pathway containing twenty-three elementary reactions.The calculation results well reproduce and rationalize the experimental findings including the selection of high boiling point reaction media of p-xylene,employment of excessive amount of BCl3 reagent,and liberation of Cl2 during the reaction process.In particular,the crucial catalytic nature of BCl3 has been clearly disclosed:In addition to activating the cyano groups,boron trichloride also works as chloride-transfer shuttle to prompt the reactions occurring and proceeding.The present result will put forwards the exploration over the formation mechanisms of phthalocyanines and porphyrins.

关键词： Subphthalocyanine DFT Reaction mechanism

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Room Temperature Chiral Reorganization of Interfacial Assemb...

Four Di-butylamino Substituents Are Better than Eight in Modulating the Electronic Structure and Third-order NLO Properties of Phthalocyanines

中国化学会第五届卟啉与酞菁学术研讨会

作者： Xiqian wang Chenxi Liu Yuying Jiang chiming wang Tianyu wang Ming Bai Jianzhuang Jiang Beijing Key Laboratory for Science and Application of Functional Molecular and Crystalline Materials Department of ChemistryUniversity of Science and Technology Beijing Marine College Shandong University at Weihai

The modulation of solid-state supramolecular assemblies at room temperature is still challenging even though it potentially has very important application prospects.Herein,based on the possibility of overall conformational changes in double-decker phthalocyanine,the room temperature chiral reorganization of solid-state assemblies was investigated.LS（Langmuir–Schaefer） films of achiral double-decker cerium phthalocyanine were fabricatedviaair–water interfacial assembly and the dependence of supramolecular chirality on the assembly of the achiral double-decker molecules was identified.Interestingly,the corresponding supramolecular chirality in the solid-state can be reorganized with amplification of the Cotton effect and formation of helical nanostructures upon storage at room temperature and atmospheric pressure.These results open new perspectives for the regulation of supramolecular assemblies.

关键词： supramolecular chirality supramolecular assemblies double-decker phthalocyanine

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Four Di-butylamino Substituents Are Better than Eight in Mod...