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Age and Gender-Related Differences in Hypotensive and Hypertensive Responses to Stellate Ganglion Block

Open Journal of Anesthesiology 2017年第7期7卷 175-183页

作者： Shigeru Yokota chikuni taneyama Hiroshi Goto Chishukai taneyama Clinic Nagano Japan Department of Anesthesiology University of Kansas Medical Center Kansas City USA

Purpose: The aim of the current study was to investigate: 1) Whether there is an association between age and changes in systolic blood pressure (SBP) after stellate ganglion block (SGB), and 2) Whether gender plays a role in hypotensive and hypertensive responses to SGB. Methods: We retrospectively reviewed SBP changes (ΔSBP) due to SGB, which were performed on 1641 subjects. SBP 30 min after SGB was compared to the baseline values. For the age study, average age of both sexes was calculated for six ranges of ΔSBP. For the gender study, the numbers of subjects (%) in various ranges of positive and negative values of ΔSBP were compared between men and women. Results: There was a significant association between age and both increasing (p Conclusions: There was an association between age and blood pressure changes after SGB and the association is most likely due to age-related alteration of cardiovascular functions. The different changes of SBP between men and women after SGB may well be attributable to gender differences of autonomic nervous regulation;sympathetic dominant man versus, parasympathetic dominant women.

关键词： Stellate Ganglion Block Hypertension Hypotension Gender Age

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Different Effects of Right and Left Stellate Ganglion Block on Systolic Blood Pressure and Heart Rate

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Open Journal of Anesthesiology 2013年第3期3卷 143-147页

作者： Shigeru Yokota chikuni taneyama Hiroshi Goto Chishukai taneyama Clinic Shiojiri City Japan Department of Anesthesiology University of Kansas Medical Center Rainbow Boulevard Kansas City USA.

Purpose: Whether or not right and left stellate ganglion blocks (SGB) affect blood pressure (BP) and heart rate (HR) differently has been controversial. The aim of this study was to analyze BP and HR changes after large numbers of right or left SGBs. Methods: A total of 16,404 right SGBs and 13,766 left SGBs were performed with 6 ml of 1% mepivacaine using the anterior paratracheal approach at C6. Changes in systolic BP and HR 30 min after SGBs were compared to the baseline values. Results: Systolic BP decreased by 25 to 49 mmHg in 10.93% and more than 50 mmHg in 0.67% of 16,404 right SGBs. Those percentages were significantly higher than corresponding percentages;8.43% and 0.49% of 13,766 left SGBs (P < 0.0001 and P < 0.05, respectively). On the other hand, systolic BP increased by 25-49 mmHg in 5.74% and more than 50 mmHg in 0.52% of left SGBs, and in 4.15% and 0.18% of right SGBs (P < 0.0001and P < 0.0001 between left and right SGBs, respectively). Right SGB caused marked reduction in HR (greater than 30 beats/min), more than left SGB (4.22% versus 2.70%, P Conclusions: Both right and left SGBs could produce clinically significant hypertension and hypotension, and also severe bradycardia. However, right SGB produces a higher incidence of significant reductions in systolic BP and HR, compared to left SGB. On the other hand, left SGB produces a significant increase in systolic BP compared to right SGB. Those differences likely stem from the hemispheric asymmetry in autonomic cardiovascular control.

关键词： Stellate Ganglion Block Hypertension Hypotension Heart Rate

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