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Computers, Materials & Continua 2016年第5期52卷 73-103页

作者： chih-ping wu Wei-Chen Li Department of Civil Engineering National Cheng Kung UniversityTainan 70101TaiwanROC

A three-dimensional(3D)asymptotic theory is reformulated for the static analysis of simply-supported,isotropic and orthotropic single-layered nanoplates and graphene sheets(GSs),in which Eringen’s nonlocal elasticity theory is used to capture the small length scale effect on the static behaviors of these.The perturbation method is used to expand the 3D nonlocal elasticity problems as a series of two-dimensional(2D)nonlocal plate problems,the governing equations of which for various order problems retain the same differential operators as those of the nonlocal classical plate theory(CST),although with different nonhomogeneous terms.Expanding the primary field variables of each order as the double Fourier series functions in the in-plane directions,we can obtain the Navier solutions of the leading-order problem,and the higher-order modifications can then be determined in a hierarchic and consistent manner.Some benchmark solutions for the static analysis of isotropic and orthotropic nanoplates and GSs subjected to sinusoidally and uniformly distributed loads are given to demonstrate the performance of the 3D nonlocal asymptotic theory.

关键词： Eringen’s nonlocal elasticity theory graphene sheets nanoplates static the perturbation method three-dimensional nonlocal elasticity

Magnetic resonance imaging findings of radiation-induced breast angiosarcoma:A case report

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World Journal of Clinical Cases 2024年第13期12卷 2237-2242页

作者： Wen-Pei wu chih-Wei Lee Department of Medical Imaging Changhua Christian HospitalChanghua 50006Taiwan Department of Radiology Changhua Christian Medical Foundation Changhua Christian HospitalChanghua 50006Taiwan

BACKGROUND Breast conservation surgery(BCS)with adjuvant radiotherapy has become a gold standard in the treatment of early-stage breast cancer,significantly reducing the risk of tumor recurrence.However,this treatment is associated with adverse effects,including the rare but aggressive radiation-induced angiosarcoma(RIAS).Despite its rarity and nonspecific initial presentation,RIAS presents a challenging diagnosis,emphasizing the importance of imaging techniques for early detection and accurate diagnosis.CASE SUMMARY We present a case of a 48-year-old post-menopausal woman who developed skin ecchymosis on the right breast seven years after receiving BCS and adjuvant radiotherapy for breast cancer.Initial mammography and ultrasound were inconclusive,showing post-treatment changes but failing to identify the underlying angiosarcoma.Contrast-enhanced breast magnetic resonance imaging(MRI)revealed diffuse skin thickening and nodularity with distinctive enhan-cement kinetics,leading to the diagnosis of RIAS.This case highlights the crucial role of MRI in diagnosing and determining the extent of RIAS,facilitating timely and appropriate surgical intervention.CONCLUSION Breast MRI is crucial for detecting RIAS,especially when mammography and ultrasound are inconclusive.

关键词： Radiation-induced angiosarcoma Radiotherapy Breast conserving surgery Breast cancer Magnetic resonance imaging Case report

Therapeutic effect of Wendan Decoction combined with mosapride on gastroesophageal reflux disease after esophageal cancer surgery

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World Journal of Clinical Cases 2024年第13期12卷 2194-2200页

作者： Yu-Jing Zhang Shen-ping wu Department of Oncology Beijing Integrated Traditional Chinese and Western Medicine HospitalBeijing 100039China

BACKGROUND Gastroesophageal reflux disease(GERD)is a common complication of esophageal cancer surgery that can affect quality of life and increase the risk of esophageal stricture and anastomotic leakage.Wendan Decoction(WDD)is a traditional Chinese herbal formula used to treat various gastrointestinal disorders,such as gastritis,functional dyspepsia,and irritable bowel syndrome.Mosapride,a prokinetic agent,functions as a selective 5-hydroxytryptamine 4 agonist,enhancing gastrointestinal motility.AIM To evaluate the therapeutic effects of WDD combined with mosapride on GERD after esophageal cancer surgery.METHODS Eighty patients with GERD were randomly divided into treatment(receiving WDD combined with mosapride)and control(receiving mosapride alone)groups.The treatment was conducted from January 2021 to January 2023.The primary outcome was improved GERD symptoms as measured using the reflux disease questionnaire(RDQ).The secondary outcomes were improved esophageal motility(measured using esophageal manometry),gastric emptying(measured using gastric scintigraphy),and quality of life[measured via the Short Form-36(SF-36)Health Survey].RESULTS The treatment group showed a notably reduced RDQ score and improved esophageal motility parameters,such as lower esophageal sphincter pressure,peristaltic amplitude,and peristaltic velocity compared to the control group.The treatment group showed significantly higher gastric emptying rates and SF-36 scores(in both physical and mental domains)compared to the control group.No serious adverse effects were observed in either group.CONCLUSION WDD combined with mosapride is an effective and safe therapy for GERD after esophageal cancer surgery.It can improve GERD symptoms,esophageal motility,gastric emptying,and the quality of life of patients.Further studies with larger sample sizes and longer follow-up periods are required to confirm these findings.

关键词： Gastroesophageal reflux disease Esophageal cancer surgery Wendan Decoction Mosapride Treatment effects Gastroesophageal reflux disease symptoms

Erythrodermic mycosis fungoides: A case report

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World Journal of Clinical Cases 2024年第1期12卷 130-135页

作者： wu-Bing Xu Ya-ping Zhang Su-ping Zhou Hao-Yang Bai Department of Radiology Shaoxing People’s HospitalKey Laboratory of Functional Molecular Imaging of Tumor and Interventional Diagnosis and Treatment of Shaoxing CityShaoxing 312000Zhejiang ProvinceChina

BACKGROUND Mycosis fungoides is the most common primary cutaneous T-cell lymphoma,whereas generalized erythroderma is rare.In this report,we describe a case of mycosis fungoides with generalized erythroderma using complete clinical data and[18F]fluoroDglucose positron emission tomography/computed tomography(18F-FDG PET/CT)images.CASE SUMMARY Systemic skin redness with desquamation for three years confirmed mycosis fungoides within one month.The patient underwent left axillary lymphadenectomy biopsy;pathological biopsy suggested abnormal T-cell lesions consistent with mycosis fungoides involving lymph nodes.The patient received methotrexate,5 mg twice weekly,as part of their chemotherapy regimen.Patients January half after discharge,no obvious cause of high fever,left axillary lymph nodes with red heat pain,and rupture entered our hospital for treatment.CONCLUSION The 18F-FDG PET/CT is essential for early diagnosis and timely treatment.

关键词： Mycosis fungoides Positron emission tomography/computed tomography Imaging Diagnosis Differential diagnosis Treatment Case report

Prediction of chemical short-range order in high-/medium-entropy alloys

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Journal of Materials Science & Technology 2024年第2期169卷 115-123页

作者： Pei-Yu Cao Jing Wang ping Jiang Yun-Jiang Wang Fu-ping Yuan Xiao-Lei wu State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of ScienceBeijing 100190China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China

Chemical short-range orders(CSROs),as the built-in sub-nanoscale entities in a high-/medium-entropy alloy(H/MEA),have aroused an ever-increasing interest.With multi-principal elements in an H/MEA to form a complex concentrated solution,a variety of sub-systems of species exist to induce the metastable ordered compounds as candidates for ultimate CSROs.The issues remain pending on the origin of CSROs as to how to judge if CSRO will form in an H/MEA and particularly,what kind of CSROs would be stably produced if there were multiple possibilities.Here,the first-principles method,along with the proposed local formation energy calculation in allusion to the atomic-scale chemical heterogeneities,is used to predict the CSRO formation based on the mechanical stability,thermodynamic formation energy,and electronic characteristics.The simulations are detailed in an equiatomic ternary VCoNi MEA with three kinds of potential compounds,i.e.,L1_(1),L1_(2),and B2,in the face-centered cubic matrix.It turns out that L1_(1)is stable but hard to grow up so as to become the final CSRO.L1_(1)is further predicted as CSROs in CrCoNi,but unable to form in FeCoNi and CrMnFeCoNi alloys.These predictions are consistent with the experimental observations.Our findings shed light on understanding the formation of CSROs.This method is applicable to other H/MEAs to design and tailor CSROs by tuning chemical species/contents and thermal processing for high performance.

关键词： Short-range order High-entropy alloy Microstructure First-principles calculation Gibbs free energy Local electronic density of states

Activatable photoacoustic bioprobe for visual detection of aging in vivo

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Chinese Chemical Letters 2024年第4期35卷 324-329页

作者： Zihong Li Jie Cheng ping Huang Guoliang wu Weiying Lin Institute of Optical Materials and Chemical Biology Guangxi Key Laboratory of Electrochemical Energy MaterialsSchool of Chemistry and Chemical EngineeringGuangxi UniversityNanning 530004China

Aging is a natural physiological process with various challenges, related to the loss of homeostasis within the organism, which is not a disease, but a significantly strong risk factor for multiple diseases, including myocardial infarction, stroke, some age-related cancers, macular degeneration, osteoarthritis, neurodegeneration, and many others. In the body, the main manifestation of aging is cellular aging, which exists within tissues and has a local or global impact on tissue function. However, the lack of effective aging detection tools has always been an issue that cannot be ignored in the field of aging research. Therefore,it is necessary to construct a non-invasive tool for in vivo detection of aging. Here, we show that the photoacoustic probe(LGAL), which has peak excitation and emission wavelengths in the near-infrared optical window, binds in vivo and at high contrast to the hallmark of aging, and allows for the microscopic imaging of aging through the intact mice. Firstly, this tool LGAL has been successfully applied to detect senescence in cells, displaying stronger photoacoustic signals than normal cells. Then, by using the photoacoustic probe, the blood vessels and tissues inside the mice can be visualized. Young and elderly mice exhibit varying intensities of photoacoustic signals, marking the first time a probe has been used to explore the aging of blood vessels and tissues inside the mice. Finally, we monitored the changes in the degree of aging during tumor treatment under photoacoustic(PA) imaging for the first time. As the treatment time increased, the degree of aging of the tumor gradually deepened. We expect the powerful tool could be a noninvasive and powerful tool for the study of aging biology.

关键词： Near-infrared Photoacoustic Aging Senescence Tumor Sa-β-gal

Federated Dynamic Client Selection for Fairness Guarantee in Heterogeneous Edge Computing

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Journal of Computer Science & Technology 2024年第1期39卷 139-158页

作者：毛莺池沈莉娟吴俊平萍吴杰 Key Laboratory of Water Big Data Technology of Ministry of Water Resources Hohai UniversityNanjing 211100China College of Computer and Information Hohai UniversityNanjing 211100China Center of Networked Computing Temple UniversityPhiladelphiaPA 19122-6096U.S.A

Federated learning has emerged as a distributed learning paradigm by training at each client and aggregat-ing at a parameter server.System heterogeneity hinders stragglers from responding to the server in time with huge com-munication costs.Although client grouping in federated learning can solve the straggler problem,the stochastic selection strategy in client grouping neglects the impact of data distribution within each group.Besides,current client grouping ap-proaches make clients suffer unfair participation,leading to biased performances for different clients.In order to guaran-tee the fairness of client participation and mitigate biased local performances,we propose a federated dynamic client selec-tion method based on data representativity(FedSDR).FedSDR clusters clients into groups correlated with their own lo-cal computational efficiency.To estimate the significance of client datasets,we design a novel data representativity evalua-tion scheme based on local data distribution.Furthermore,the two most representative clients in each group are selected to optimize the global model.Finally,the DYNAMIC-SELECT algorithm updates local computational efficiency and data representativity states to regroup clients after periodic average aggregation.Evaluations on real datasets show that FedS-DR improves client participation by 27.4%,37.9%,and 23.3%compared with FedAvg,TiFL,and FedSS,respectively,tak-ing fairness into account in federated learning.In addition,FedSDR surpasses FedAvg,FedGS,and FedMS by 21.32%,20.4%,and 6.90%,respectively,in local test accuracy variance,balancing the performance bias of the global model across clients.

关键词： federated learning fairness computational efficiency data distribution client selection client grouping

M2 macrophage-related molecular subtypes and prognostic index for prostate cancer patients through integrating single-cell and bulk RNA sequencing analysis

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Genes & Diseases 2024年第4期11卷 131-133页

作者： Dechao Feng Xu Shi Dengxiong Li Ruicheng wu Jie Wang wuran Wei ping Han Department of Urology Institute of UrologyWest China HospitalSichuan UniversityChengduSichuan 610041China

Prostate cancer(PCa)is considered as an age-related disease and accounts for the most prevalence of urinary malignancies in men.1 We previously analyzed the cellular landscape of tumor microenvironment in PCa patients,where we found that cancer-related fibroblasts might play an important role in tumorigenesis and the development of PCa and tumor-associated macrophage(TAM)could function synergistically with them.2 Thus,we further integrated single-cell and bulk RNA sequencing with meta-analysis to specify the prognostic effect of TAM on PCa and construct molecular subgroups and predictive index to guide clinical practice.

关键词： patients macrophage cancer

An adaptive finite-difference method for seismic traveltime modeling based on 3D eikonal equation

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Petroleum Science 2024年第1期21卷 195-205页

作者： Bao-ping Qiao Qing-Qing Li Wei-Guang He Dan Zhao Qu-Bo wu CNNC Beijing Research Institute of Uranium Geology Beijing 100029China National Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)Qingdao 266580ShangdongChina SINOPEC Geophysical Research Institute Nanjing211103JiangsuChina

3D eikonal equation is a partial differential equation for the calculation of first-arrival traveltimes and has been widely applied in many scopes such as ray tracing,source localization,reflection migration,seismic monitoring and tomographic imaging.In recent years,many advanced methods have been developed to solve the 3D eikonal equation in heterogeneous media.However,there are still challenges for the stable and accurate calculation of first-arrival traveltimes in 3D strongly inhomogeneous media.In this paper,we propose an adaptive finite-difference(AFD)method to numerically solve the 3D eikonal equation.The novel method makes full use of the advantages of different local operators characterizing different seismic wave types to calculate factors and traveltimes,and then the most accurate factor and traveltime are adaptively selected for the convergent updating based on the Fermat principle.Combined with global fast sweeping describing seismic waves propagating along eight directions in 3D media,our novel method can achieve the robust calculation of first-arrival traveltimes with high precision at grid points either near source point or far away from source point even in a velocity model with large and sharp contrasts.Several numerical examples show the good performance of the AFD method,which will be beneficial to many scientific applications.

关键词： 3D eikonal equation Accurate traveltimes Global fast sweeping 3D inhomogeneous media Adaptive finite-difference method

Recent advances in bioinspired vision systems with curved imaging structures

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Rare Metals 2024年第4期43卷 1407-1434页

作者： Ze-ping He Xun Han Wen-Qiang wu Zhang-Sheng Xu Cao-Feng Pan CAS Center for Excellence in Nanoscience Beijing Key Laboratory of Micro-Nano Energy and SensorBeijing Institute of Nanoenergy and NanosystemsChinese Academy of Sciences School of Nanoscience and Technology University of Chinese Academy of Sciences ZJU-Hangzhou Global Scientific and Technological Innovation Center School of Micro-Nano ElectronicsZhejiang University Institute of Microscale Optoelectronics Shenzhen University

Limited by the planar imaging structure,the commercial camera needs to introduce additional optical elements to compensate for the curved focal plane to match the planar image sensor.This results in a complex and bulky structure.In contrast,biological eyes possess a simple and compact structure due to their curved imaging structure that can directly match with the curved focal plane.Inspired by the structures and functions of biological eyes,curved vision systems not only improve the image quality,but also offer a variety of advanced functions.Here,we review the recent advances in bioinspired vision systems with curved imaging structures.Specifically,we focus on their applications in implementing different functions of biological eyes,as well as the emerging curved neuromorphic imaging systems that incorporate bioinspired optical and neuromorphic processing technologies.In addition,the challenges and opportunities of bioinspired curved imaging systems are also discussed.

关键词： Bioinspired Curved vision system Compound eye Chambered eye Neuromorphic