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AN AHP MODEL FOR BRINGING EXPERTS TO CONSENSUS ON MEDICAL PAYMENT STANDARDS

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Journal of Systems Science and Systems Engineering 2006年第2期15卷 247-255页

作者： Yuan-Huei HUANG pei-Yeh chang chih-Young HUNG Kuei-Ing WANG King-Jen chang Department of Surgery Hsin-Chu General HospitalTaiwanChina Department of Pediatric Surgery Chang Gung Children’s HospitalChang Gung UniversityCollege of MedicineTaiwanChina Institute of Management of Technology National Chiao Tung UniversityTaiwanChina Department of Information Management Ming Hsin University of Science and TechnologyTaiwanChina Department of Surgery National Taiwan University HospitalTaiwanChina

Many countries with health insurance systems conduct periodic payment standards reform. How to reach consensus in setting payment standards among different specialties with different agendas has become a critical issue. The purpose of this study is to construct an analytic hierarchy process （AHP） model to obtain judgments from experts about the importance of ＂factors related to establishing payment standards in the national health insurance program＂. Under this goal, the first tier contains four evaluation aspects, and the second tier contains sixteen evaluation criteria divided into four groups The AHP model was then used to collect and combine the opinions of experts through an empirical study. The results can be directly used to formulate standard values as the basis for establishing payment standards. The results of our study strongly support that an AHP model is effective in forming a consensus among surgical specialists.

关键词： National Health Insurance Analytic Hierarchy Process payment standards

Deciphering H^(+)/Zn^(2+) co-intercalation mechanism of MOF-derived2D MnO/C cathode for long cycle life aqueous zinc-ion batteries

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Rare Metals 2022年第11期41卷 3729-3739页

作者： Zheng-Xiang Zhu Zhang-Wen Lin Zhong-Wei Sun pei-Xin Zhang chang-Ping Li Rui Dong Hong-Wei Mi College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen518060China Guangdong Engineering Technology Research Centre for Distributed and Intelligent Small Solar Energy Storage Shenzhen Hello Tech Energy Co.Ltd.Shenzhen518100China Research Center for Eco-Environmental Engineering Dongguan University of TechnologyDongguan523808China Shenzhen Wesmart Sensor Technology Co. Ltd.Shenzhen518118China

Poor conductivity,sluggish ion diffusion kinetics and short cycle life hinder the further development of manganese oxide in aqueous zinc-ion batteries(AZIBs).Exploring a cathode with high capacity and long cycle life is critical to the commercial development of AZIBs.Herein,a two-dimensional(2D) MnO/C composite derived from metal organic framework(MOF) was prepared.The 2D MnO/C cathode exhibits a remarkably cyclic stability with the capacity retention of 90.6% after 900 cycles at 0.5 A·g^(-1) and maintains a high capacity of 120.2 mAh·g^(-1)after 4500 cycles at 1.0 A·g^(-1).It is demonstrated that MnO is converted into Mn_(3)O_(4) through electrochemical activation strategy and shows a Zn^(2+)and H^(+)co-intercalation mechanism.In general,this work provides a new path for the development of high-performance AZIBs cathode with controllable morphology.

关键词： Aqueous zinc-ion battery MnO/C Morphology design H^(+)/Zn^(2+)co-insertion

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生物支架材料及打印技术修复骨缺损

中国组织工程研究 2024年第3期28卷 479-485页

作者：孔祥宇王兴裴志伟常家乐李斯琴郝廷何万雄张葆鑫贾燕飞内蒙古医科大学研究生院内蒙古自治区呼和浩特市010000 巴彦淖尔市医院内蒙古自治区巴彦淖尔市015000 内蒙古医科大学第二附属医院内蒙古自治区呼和浩特市010030

背景:近年来随着生物支架材料和生物打印技术的发展,组织工程骨成为了骨缺损修复的研究热点。目的:简述当前骨缺损的治疗方式,总结制备组织工程骨支架的生物材料及生物打印技术,探讨生物材料和打印技术在组织工程中的应用及目前面临的... 详细信息

背景:近年来随着生物支架材料和生物打印技术的发展,组织工程骨成为了骨缺损修复的研究热点。目的:简述当前骨缺损的治疗方式,总结制备组织工程骨支架的生物材料及生物打印技术,探讨生物材料和打印技术在组织工程中的应用及目前面临的挑战。方法:以“bone defect,tissue engineering,biomaterials,3D printing technology,4D printing technology,bioprinting,biological scaffold,bone repair”或“骨缺损,组织工程,生物材料,3D打印技术,4D打印技术,生物打印,生物支架,骨修复”等作为检索词,应用计算机在中国知网、PubMed、Web of Science数据库检索2009-01-01/2022-12-01发表的相关文献,最后经第一作者筛除并追加收录优质参考文献,共纳入93篇文章进行综述。结果与结论:骨缺损的治疗方式主要有骨移植、膜引导再生技术、基因治疗、骨组织工程技术等,最佳的治疗方式仍没有定论。骨组织工程技术是治疗骨缺损的新兴技术,通过构建能促进成骨细胞增殖分化及增强骨形成能力的三维结构,成为当前研究的重点热点技术。生物支架材料多种多样,各具特点,有利有弊,单一的生物材料无法满足组织工程骨对支架的需求,通常将多种材料复合互补使支架在满足力学性能需求的同时兼顾生物性能。生物打印技术能对支架的孔隙进行调节、构建复杂的空间结构,更利于细胞的黏附增殖和分化。新兴的4D打印技术引入“时间”作为第四维度,使制备的支架具有动态性,随着智能材料的同步发展,4D打印技术为未来骨缺损高效修复提供了可能。

关键词：骨缺损组织工程生物材料 3D打印技术 4D打印技术生物打印生物支架骨修复

Intelligent microneedle patch with prolonged local release of hydrogen and magnesium ions for diabetic wound healing

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Bioactive Materials 2023年第6期24卷 463-476页

作者： pei Wang Jiayingzi Wu Haiyan Yang Hengke Liu Tianyu Yao chang Liu Yan Gong Mingsong Wang Guangyu Ji Peng Huang Xiansong Wang Department of Thoracic Surgery Shanghai Key Laboratory of Tissue EngineeringShanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai200011China Marshall Laboratory of Biomedical Engineering International Cancer CenterLaboratory of Evolutionary Theranostics(LET)School of Biomedical EngineeringShenzhen University Medical SchoolShenzhen518060China Center of Hydrogen Science Shanghai Jiao Tong UniversityShanghai200240China

Diabetes mellitus,an epidemic with a rapidly increasing number of patients,always leads to delayed wound healing associated with consistent pro-inflammatory M1 polarization,decreased angiogenesis and increased reactive oxygen species(ROS)in the microenvironment.Herein,a poly(lactic-co-glycolic acid)(PLGA)-based microneedle patch loaded with magnesium hydride(MgH_(2))(MN-MgH_(2))is manufactured for defeating diabetic wounds.The application of microneedle patch contributes to the transdermal delivery and the prolonged release of MgH_(2) that can generate hydrogen(H_(2))and magnesium ions(Mg^(2+))after reaction with body fluids.The released H_(2) reduces the production of ROS,transforming the pathological microenvironment induced by diabetes mellitus.Meanwhile,the released Mg^(2+)promotes the polarization of pro-healing M2 macrophages.Consequently,cell proliferation and migration are improved,and angiogenesis and tissue regeneration are enhanced.Such intelligent microneedle patch provides a novel way for accelerating wound healing through steadily preserving and releasing of H_(2) and Mg^(2+)locally and sustainably.

关键词： Microneedle patch Magnesium hydride Hydrogen Magnesium ion Diabetic wound healing

Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system

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Journal of Molecular Cell Biology 2020年第5期12卷 327-336页

作者： Ya-Jie Xu pei-pei Liu Shyh-chang Ng Zhao-Qian Teng chang-Mei Liu State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Savaid Medical School University of Chinese Academy of SciencesBeijing 100049China Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijing 100101China

High-throughput sequencing has facilitated the identification of many types of non-coding RNAs(ncRNAs)involved in diverse cellular processes.NcRNAs as epigenetic mediators play key roles in neuronal development,maintenance,and dysfunction by controlling gene expression at multiple levels.NcRNAs may not only target specific DNA or RNA for gene silence but may also directly interact with chromatin-modifying proteins like Polycomb group(PcG)proteins to drive orchestrated transcriptional programs.Recent significant progress has been made in characterizing ncRNAs and PcG proteins involved in transcriptional,post-transcriptional,and epigenetic regulation.More importantly,dysregulation of ncRNAs,PcG proteins,and interplay among them is closely associated with the pathogenesis of central nervous system(CNS)disorders.In this review,we focus on the interplay between ncRNAs and PcG proteins in the CNS and highlight the functional roles of the partnership during neural development and diseases.

关键词： epigenetics Polycomb complexes non-coding RNAs central nervous system neurological diseases

西宁盆地黄土区草本植物边坡电阻率与土体物理力学性质关系研究

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岩土力学 2024年第2期45卷 477-488页

作者：赵迎宵何伟鹏丁晓英詹俊胡夏嵩刘昌义缪晓星王延秀卢海静邢光延李华坦张培豪青海大学地质工程系青海西宁810016 青海省第三地质勘查院青海西宁810008 青海省水土保持中心青海西宁810000 青海大学农牧学院青海西宁810016 青海大学土木水利学院青海西宁810016

为研究高寒干旱-半干旱环境黄土区种植不同类型草本植物边坡土体电阻率与其物理力学性质之间的定量关系,探讨电阻率数值反映边坡土体物理力学性质及其变化特征,在西宁盆地长岭沟流域自建试验区选取未种植裸坡以及种植生长期为3年的垂穗... 详细信息

为研究高寒干旱-半干旱环境黄土区种植不同类型草本植物边坡土体电阻率与其物理力学性质之间的定量关系,探讨电阻率数值反映边坡土体物理力学性质及其变化特征,在西宁盆地长岭沟流域自建试验区选取未种植裸坡以及种植生长期为3年的垂穗披碱草(Elymus nutans Griseb.)、老芒麦(Elymus sibiricus Linn.)、细茎冰草(Agropyron trachycaulum Linn.Gaertn.)、高羊茅(Festuca arundinacea Schreb.)的边坡共5种类型边坡为研究对象。通过开展边坡土体密度、含水率、含根系与不含根系土体直剪试验,对比不同草本植物根系对边坡土体物理力学性质的影响。在此基础上,利用二维电阻率层析成像方法建立不同边坡土体物理力学性质指标与土体电阻率间的定量关系。结果表明:(1)与未种植裸坡相比较,种植老芒麦边坡上层(0~10 cm)土体含水率增幅最大为26.53%;种植高羊茅边坡上层(0~10 cm)土体平均密度降幅最大为18.30%;种植垂穂披碱草边坡上层(0~10cm)土体黏聚力附加值最大,且为未种植裸坡的2.75倍。(2)5种类型边坡的电阻率受根系分布和边坡位置因素的共同影响,电阻率随着深度增加逐渐降低。4种草本边坡坡面以下0~20cm处土体电阻率均较裸坡大,该深度为根系分布大致范围。(3)5种边坡土体物理力学性质与电阻率数据之间存在拟合方程式(相关系数R2为0.48~0.77),且通过Pearson相关性分析得到边坡土体黏聚力c与电阻率间的相关性相对最高,相关系数R2为0.765。上述研究结果反映出可通过电阻率层析成像技术反映边坡土体物理力学性质,以及边坡土体中植物根系分布特征,可为研究区及其周边地区采用植物有效防治水土流失、浅层滑坡等灾害提供理论依据和实际指导意义。

关键词：高寒干旱-半干旱环境西宁盆地二维电阻率层析成像边坡土体电阻率土体物理力学性质 Pearson相关性分析

基于ICAE算法的城市群高速公路网布局优化研究

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重庆交通大学学报（自然科学版） 2024年第7期43卷 70-76,103页

作者：裴玉龙闻宇航王婉佼潘胜东北林业大学交通研究中心哈尔滨黑龙江150040

为提升城市群高速公路网通达程度和可达性水平,建立了体现城市群特征的优化模型,并改进了帝国竞争算法,以哈长城市群为案例,探究布局优化效果。采用高速公路出行时间确定城市群可达性等级,通过考虑可达性、距离等参数建立优化模型;引入... 详细信息

为提升城市群高速公路网通达程度和可达性水平,建立了体现城市群特征的优化模型,并改进了帝国竞争算法,以哈长城市群为案例,探究布局优化效果。采用高速公路出行时间确定城市群可达性等级,通过考虑可达性、距离等参数建立优化模型;引入进化算子改进算法,构建进化帝国竞争算法;根据哈长城市群特征确定约束条件并求解,利用求解节点和周边道路网确定优化方案。研究表明:改进的算法收敛精度提高16.4%,时间缩短42.4%,共求解出6个节点,规划新建高速公路6条,改建高速公路14条,优化后的城市群高速公路2 h交通圈覆盖范围达到65.3%,14个县域交通圈等级上升,优化方案扩大了城市群2 h交通圈范围。

关键词：交通工程公路交通高速公路网帝国竞争算法城市群可达性

A Remark on the Generalized Second Order Toda System

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Acta Mathematica Sinica,English Series 2013年第9期29卷 1691-1702页

作者： Rui chang pei School of Mathematics and Statistics Tianshui Normal University

In this paper, we establish a priori estimates to the generalized second order Toda system{-Δu1（x）=2R1（x）eu1-R2eu2,-Δu2（x）=R1（x）eu1＋2R2eu2 in R2 , and discuss the convergence and asymptotic behavior of its solutions, where Ri（x）, i=1, 2, is bounded function in R2 . Consequently, we prove that all the solutions satisfy an identity, which is somewhat a generalization of the well-known Kazdan-Warner condition.

关键词： Second order Toda system asymptotic behavior priori estimates convergence

数字化营销工具在运营商创新产品发展过程中的应用

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信息通信技术与政策 2024年第3期50卷 73-78页

作者：张春艳郭玉华孟祥龙常沛包海伦中国联合网络通信集团有限公司市场部北京100033

鉴于数字化营销工具是电信运营商推进落实创新服务模式的有效手段,能够帮助一线营销人员精准识别目标客户、理解客户需求、优化营销策略、提高营销效率和服务积极性,从而为电信运营商实现由基础通信产品销售商转变为整合型、多元化数字... 详细信息

鉴于数字化营销工具是电信运营商推进落实创新服务模式的有效手段,能够帮助一线营销人员精准识别目标客户、理解客户需求、优化营销策略、提高营销效率和服务积极性,从而为电信运营商实现由基础通信产品销售商转变为整合型、多元化数字服务提供商助力,分析了数字化营销工具如何赋能营销运营、提升营销效率,提出了数字化营销工具的架构设计方案,探寻了复杂营销环境下电信运营商的营销转型之道。

关键词：营销工具运营商增值业务互联网