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Impact of disease severity on gastric residual volume in critical patients

World Journal of Gastroenterology 2011年第15期17卷 2007-2012页

作者： chien-Wei Hsu Shu-Fen Sun David Lin lee Shoa-Lin Lin Kam-Fai Wong Hsiu-hua huang Hung-Ju Li Department of Medicine School of Medicine National YangMing University Taipei Taiwan China Intensive Care Unit Department of Medicine Kaohsiung Veterans General Hospital Kaohsiung City 813 Taiwan China Department of Physical Medicine and Rehabilitation Kaohsiung Veterans General Hospital Kaohsiung City 813 Taiwan China Institute of Statistics National University of Kaohsiung Kaohsiung City 813 Taiwan China Department of Nutrition Kaohsiung Veterans General Hospital Kaohsiung City 813 Taiwan China

AIM: To investigate whether illness severity has an impact on gastric residual volume (GRV) in medical critically ill patients. METHODS: Medical intensive care unit (ICU) patients requiring nasogastric feeding were enrolled. Sequential Organ Failure Assessment (SOFA) score was assessed immediately preceding the start of the study. Acute Physiology and Chronic Health Evaluation (APACHE) Ⅱ scores were recorded on the first, fourth, seventh, and fourteenth day of the study period. GRV was measured every 4 h during enteral feeding. The relationship be-tween mean daily GRV and SOFA scores and the correlation between mean daily GRV and mean APACHE Ⅱ score of all patients were evaluated and compared. RESULTS: Of the 61 patients, 43 patients were survivors and 18 patients were non-survivors. The mean daily GRV increased as SOFA scores increased (P < 0.001, analysis of variance). Mean APACHE Ⅱ scores of all patients correlated with mean daily GRV (P = 0.011, Pearson correlation) during the study period. Patients with decreasing GRV in the first 2 d had better survival than patients without decreasing GRV (P = 0.017, log rank test). CONCLUSION: GRV is higher in more severely ill medical ICU patients. Patients with decreasing GRV had lower ICU mortality than patients without decreasing GRV.

关键词： Critical care Outcome Residual volume Severity of illness index Tube feeding

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Efficacy and Safety of Herbal Medicine Yun-Cai Tea in the Treatment of Hyperlipidemia:A Double-Blind Placebo-Controlled Clinical Trial

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Chinese Journal of Integrative Medicine 2015年第8期21卷 587-593页

作者： chien-Ying lee Min-chien Yu Chun-Che Lin Ming-Yung lee James Cheng-Chung Wei Hung-Che Shih Institute of Medicine Chung Shan Medical University Department of Pharmacy Chung Shan Medical University Hospital Department of Internal Medicine Chung Shan Medical University Hospital Department of Integrated Chinese and Western Medicine Chung Shan MedicalUniversity Hospital Division of Hepatogastroenterology Department of Internal MedicineChung Shan Medical University Hospital Department of Statistics and Informatics Science Providence University Graduate Institute of Integrated Medicine China Medical University Department of Pharmacology Chung Shan Medical University

Objective： Animal studies have demonstrated a lipid-modulating effect of yun-cai tea. However, little is known about the lipid-lowering effect in *** aim of this study was to evaluate the lipid lowering effects and safety of yun-cai tea in patients with elevated lipid levels in a human clinical trial. Methods： This was a 12-week, randomly assigned, parallel-group, double-blind, and placebo-controlled pilot clinical study. Sixty primary hyperlipidemia patients were included and randomly assigned to the yun-cai tea group （30 patients） and the placebo group （30 patients）, for 8 weeks of treatment and 4 weeks of follow-up. The primary endpoint was changes in plasma low-density lipoprotein-cholesterol （LDL-C） at 8 weeks. The secondary endpoints included total cholesterol （TC） and triglycerides （TG）. Results： Our results revealed no statistically significant differences in LDL-C and TC between the two groups. Despite the lack of a statistically significant difference in the level of TG between the two groups, a declining trend was noted. A significant reduction of TG was observed in the yun-cai tea group at week 8, compared to baseline （P=0.048）. The incidence of stomach discomfort, gastroesophageal reflux, diarrhea, and constipation was slightly higher in the yun-cai tea group. No other significant adverse events were found. Conclusions： It is unlikely that yun-cai tea used had a blood lipid reduction effect. Further larger scale clinical trials with a longer duration and larger dose are necessary.

关键词： yun-cai tea low-density lipoprotein-cholesterol total cholesterol triglycerides

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Experimental Study of Rotational Effect on Stalling

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Chinese Physics Letters 2013年第6期30卷 123-126页

作者： lee Hsiao Mun WU Yan-hua School of Mechanical and Aerospace Engineering Nanyang Technological University50 Nanyang AvenueSingapore 639798

Tomographic particle image velocimetry(TPIV)and static pressure measurements are performed in a wind tunnel on a scaled model of the rotor blade of a 5 kW horizontal-axis wind turbine designed by using the blade element momentum *** study is to investigate the physics of the stall-delay phenomenon observed for a rotating *** TPIV experiments are conducted at several span-wise locations of the *** separated flow from the rotating blade is studied and compared with the case of the static stall at similar angles of attack and Reynolds number Re.

关键词： method. blade rotating

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Effect of Thermal Refining on Mechanical Properties of Annealed SAE 4130 by Multilayer GTAW

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Journal of Iron and Steel Research International 2012年第7期19卷 71-78页

作者： I K lee C L Chung Y T lee Y T chien Department of Materials Science and Engineering Da-Yeh University

During the first welding process in manufacturing a precise seam container, the steel material must first undergo a full annealing treatment. Multilayer welding operations are conducted and then applied with refining treatment to obtain the goal by hardening. The influence of thermal refining on mechanical properties of annealed SAE 4130 by multilayer GTAW （gas tungsten arc welding） was discussed. The AW （annealing＋welding） and AWST （annealing＋welding＋solution＋tempering） occurred with a minimum hardness value at GGHAZ （grain growth heat affected zone） due to coarse grain growth~ the hardness occurred with sudden drops between the multilayer welding, but was still larger than the minimum value at HAZ （heat affected zone）. The welded joint efficiency of the AWST was 89.9%, with the elongation reduced to 77.2% of AST （annealing＋solution＋tempering）. The cross section of the tensile samples both appeared with a uniform dimple-shaped structure, and however the necking for AST was greater than that for AWST. The impact value for AWST was 166.5% of AST. Moreover, from microstructure observations, it was found that AWST had a greater tendency to ductile failure than AST. These results can be inferred., the process of steady pressure and the initial position of the precision tube breakage HAZ. However, when stress occurs instantly, HAZ can absorb more energy, therefore the initial damage does not occur.

关键词： thermal refining SAE 4130 multilayer welding GTAW

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The role of nickel oxide additive in lowering the carbon dioxide sorption temperature of CaO

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Journal of Energy Chemistry 2015年第2期24卷 225-231页

作者： Zhi hua lee Satoshi Ichikawa Keat Teong lee Abdul Rahman Mohamed Low Carbon Economy (LCE) Research Group School of Chemical EngineeringEngineering Campus Universiti Sains Malaysia 14300 Nibong Tebal Pulau Pinang Malaysia Department of Chemical Engineering Faculty of Engineering and ScienceUniversiti Tunku Abdul Rahman Jalan Genting Kelang 53300 Setapak Kuala Lumpur Malaysia Institute for Nano Science Design Osaka University 1-3 Machikaneyama Toyonaka Osaka 560-8531 Japan

A new type of calcium-based regenerable carbon dioxide （CO_2） sorbent, CaO-NiO, was synthesized via the sol-gel method. The as synthesized CO_2 sorbent was in the form of nanoparticles. The CO_2 sorption temperature and capacity of the sorbent were examined using thermogravi- metric analysis （TGA）. The CaO-NiO sorbent is able to capture CO_2 at a lower sorption temperature （465 ℃） than pure calcium oxide （CaO）（600 ℃）. The role of NiO in the CaO-NiO sorbent in lowering the CO_2 sorption temperature was also investigated. The sorbent was char- acterized by X-ray diffractometer （XRD）, N_2 adsorption-desorption analysis, high resolution transmission electron microscopy （HRTEM） and scanning electron microscopy （SEM）. CaO and NiO were found to coexist in the sorbent. Neither solid solution nor mixed metal oxide was formed. NiO did not react with CO_2 in the sorption process; but it worked like a catalyst to promote the CaO carbonation reaction. It is suggested that this new CaO-NiO sorbent may have a promising application as an effective CO_2 sorbent with lower energy consumption.

关键词： carbon dioxide calcium oxide nickel oxide sorption temperature

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Sclerosing encapsulating peritonitis in a liver transplant patient: A case report

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World Journal of Gastroenterology 2005年第34期11卷 5412-5413页

作者： chien-hua Lin Jyh-Cherng Yu Cheng-Jueng Chen Chung-Bao Hsieh Division of General Surgery Department of Surgery Tri-Service General Hospital National Defense Medical Center Taipei Taiwan China

We report a patient with HBV-related hepatocellular carcinoma （HCC） and refractory ascites who had received a peritoneal-venous shunt （PVS） 1 year before liver transplantation, Urgent surgical intervention following bowel obstruction and failure of immunosuppression therapy. No intestinal obstruction was found during an initial PVS. However, intestinal obstruction developed 2 was found upon exploration. This is the first reported case of cocoon abdomen caused by PVS and exacerbated by liver transplantation.

关键词： Sclerosing encapsulating peritonitis Cocoon abdomen Intestinal obstruction Liver transplantation

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Evaluation of the Potential Inhibitory Activity of A Combination of ***,*** and *** on Helicobacter Pylori：A Randomized Double-Blind Placebo-Controlled Clinical Trial

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Chinese Journal of Integrative Medicine 2017年第3期23卷 176-182页

作者： chien-Ying lee Hung-Che Shih Min-chien Yu Ming-Yung lee Ya-Lan Chang Ya-Yun Lai Yi-Ching lee Yu-Hsiang Kuan Chun-Che Lin Institute of Medicine Chung Shan Medical UniversityTaichungTaiwan 40201China Department of Pharmacy Chung Shan Medical University HospitalTaichungTaiwan 40201China Department of Medicine Chung Shan Medical UniversityTaichungTaiwanChina Department of Integrated Chinese and Western Medicine Chung Shan Medical University HospitalTaichungTaiwan 40201China Department of Statistics and Informatics Science Providence UniversityChina 43301 Department of Applied Cosmetology National Tainan Junior College of NursingTaiwan 700 China Division of Hepatogastroent erology Department of Internal MedicineChung Shan Medical University HospitalTaichungTaiwan 40201China

Objective： To investigate whether three strains of probiotics, L. acidophilus, L. rhamnosus, and L. sporogenes, had significant inhibitive effects on Helicobacter pylori（H. pylori）. Methods： This is a 4-week, randomly assigned, parallel-group, doubled-blind, and placebo-controlled study. Fifty patients with a positive H. pylori infection urea breath test（△UBT） result 〉 10% and without ulcer symptoms were randomized into a treatment group and a placebo group by a computer generated allocation sheet with 1：1. These subjects took one capsule of probiotics or placebo twice daily. The primary measurement was the change in △UBT values. Results： The △UBT values during the 4-week treatment period and the 2-week follow-up period were not significantly different between the treatment group and the placebo group, indicating that the inhibitive effects on H. pylori were comparable between both groups. The monocyte count（%） was 5.77±1.11 in the treatment group versus 5.09±1.12 in the placebo group（P=0.044）, and the basophile count was 0.55±0.32 in the treatment group versus 0.36±0.23 in the placebo group（P=0.024） at week 2 of the treatment period, both of which reached statistical significance. The monocyte count was 5.75±1.26 in the treatment group and 4.72±0.99 in the placebo group at the end of the follow-up period（P=0.003）. Conclusions： There was no significant inhibitive effects of the three probiotic strains（L. acidophilus, L. rhamnosus, and L. sporogenes） on H. pylori. Probiotics can not play the same role as antibiotics in the eradication of H. pylori, the role of probiotics is likely to be important as adjuvant to the triple or quadruple therapy for H. pylori, especially in resistance cases.

关键词： probiotics Helicobacter pylori urea breath test randomized double-blind placebo-controlled trial

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Finite Element Analysis of Axisymmetric Elastic Body Problems

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Applied Mathematics and Mechanics(English Edition) 1980年第1期1卷 23-34页

作者： chien, Wei-zang(Tsing hua University, Peking) Tsing hua University Peking

Linear form functions are commonly used in a long time for a toroidal volume element swept bya triangle revolved about the symmetrical axis for general axisymmetrical stress *** is diffi-cult to obtain the rigidity matrix by exact integration,and instead,the method of approximate in-tegration is *** the locations of element close to the symmetrical axis,the accuracy of this ap-proximation deteriorates very *** exact integration have been suggested by various authorsfor the calculation of rigidity ***,it is shown in this paper that these exact integrationscan only be used for those axisymmetric bodies With central *** solid axisymmetric body,itcan be proved that the calculation fails due to the divergent property of rigidity matrix *** this paper a new form function is *** this new form function,the radial displacementu vanishes as radial coordinates r approach to *** calculated rigidity matrix is convergenteverywhere,including these triangular

关键词： Finite Element Analysis of Axisymmetric Elastic Body Problems

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Global Analysis of Direct Targets of Secondary Wall NAC Master Switches in Arabidopsis

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Molecular Plant 2010年第6期3卷 1087-1103页

作者： Ruiqin Zhong Chanhui lee Zheng-hua Ye Department of Plant Biology University of Georgia Athens GA 30602 USA

We report the genome-wide analysis of direct target genes of SND1 and VND7, two Arabidopsis thaliana NAC domain transcription factors that are master regulators of secondary wall biosynthesis in fibers and vessels, respectively. Systematic mapping of the SND1 binding sequence using electrophoretic mobility shift assay and transactivation analysis demonstrated that SND1 together with other secondary wall NACs （SWNs）, including VND6, VND7, NST1, and NST2, bind to an imperfect palindromic 19-bp consensus sequence designated as secondary wall NAC binding element （SNBE）, （T/A）NN（C/T）（TICIG）TNNNNNNNA（AIC）GN（AJCIT）（A/T）, in the promoters of their direct targets. Genome-wide analysis of direct targets of SND1 and VND7 revealed that they directly activate the expression of not only downstream transcription factors, but also a number of non-transcription factor genes involved in secondary wall biosynthesis, cell wall modification, and programmed cell death, the promoters of which all contain multiple SNBE sites. SND1 and VND7 directly regulate the expression of a set of common targets but each of them also preferentially induces a distinct set of direct targets, which is likely attributed to their differential activation strength toward SNBE sites. Complementation study showed that the SWNs were able to rescue the secondary wall defect in the sndl nstl mutant, indicating that they are functionally interchangeable. Together, our results provide important insight into the complex transcriptional program and the evolutionary mechanism underlying secondary wall biosynthesis, cell wall modification, and programmed cell death in secondary wall-containing cell types.

关键词： Arabidopsis secondary cell walls NAC transcription factor transcriptional regulation.

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Streptococcal toxic shock syndrome after hemorrhoidectomy: A case report

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World Journal of Clinical Cases 2021年第33期9卷 10238-10243页

作者： chien-Yu lee Yuarn-Jang lee Chia-Che Chen Li-Jen Kuo Department of Pediatrics Taoyuan General HospitalMinistry of Health and WelfareTaoyuan 32748Taiwan Division of Infectious Diseases Department of Internal MedicineTaipei Medical University HospitalTaipei 11031Taiwan Division of Infectious Diseases Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11031Taiwan Division of Colorectal Surgery Department of SurgeryTaipei Medical University HospitalTaipei 11031Taiwan Department of Surgery School of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11031Taiwan

BACKGROUND Streptococcal toxic-shock syndrome after hemorrhoidectomy is rare but may be *** A streptococci have produced various surface proteins and exotoxins due to genetic changes to fight the human body’s immune *** life threatening infection after hemorrhoidectomy rarely occurs,all surgeons should be aware of the potential complications of severe sepsis after hemorrhoidectomy and keep in mind their clinical presenting features in order to diagnose early and administer appropriate and effective therapeutic drugs *** SUMMARY Here,we present a case of a 56-year-old man with a painful thrombotic external hemorrhoid who presented to our outpatient department for *** was no history of systemic diseases or recent disease *** was suggested and *** surgery,the patient developed hypotension,tachycardia,fever with chills and renal function impairment on day 2 *** clinical condition progressed to severe septic shock and metabolic *** patient responded poorly to treatment and expired after 1 d even with use of extracorporeal membrane *** results of the blood and wound cultures showed group A streptococcus *** Although extremely uncommon,all surgeons should be aware of these potential life-threatening septic complications and alert to the presenting features for patients receiving hemorrhoidectomy.

关键词： Hemorrhoid Sepsis Streptococcus pyogenes Streptococcal toxic shock syndrome Case report

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