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Assessment of Migraine Disability Using the Migraine Disability Assessment Questionnaire in Young Nigerians

World Journal of Neuroscience 2018年第4期8卷 411-422页

作者： Birinus Adikaibe Ezeala-Adikaibe Chinwe Onyekonwu Uchenna Ijoma Nkeiru Mbadiwe Oluchi Stella Ekenze Casmir Orjioke Ekenechukwu Young Peter Chime Obinna Onodugo Obumneme Anyim chidim.a brenda nwatu Celestine Okwara Ikenna Obinwanne Onwuekwe Department of Medicine University of Nigeria Teaching Hospital Enugu Nigeria Department of Medicine Enugu State University of Science and Technology Enugu Nigeria

Background and purpose: Migraine is a common debilitating condition with variable prevalence in young Nigerians with significant deterioration in normal daily functioning and in the quality of life. Few data exist on the disability of migraine in Nigeria. The aim of this study was to measure the headache related disability of patients with migraine using the MIDAS among young Nigerians. Methods: This was a cross sectional study conducted in Enugu South East Nigeria. The questionnaire was designed to assess headache profiles according to ICHD-III beta and disability using the Migraine Disability Assessment Questionnaire. Results: About 40.6% of migraineurs were concerned about headache attacks and 39.1% consulted a doctor because of migraine. Most students were affected due to reduced effectiveness at school and number of days missed from housework—18.8% and 20.3% respectively. Overall, 47.8% had at least one day affected by headache in the last three months. The mean number of days disabled by headache was 14.3 days. The mean headache frequency was 5.7 days and the mean pain intensity was 4.2. About 27.5% of the migraineurs had moderate to severe disability due to migraine. There were no significant differences between males and females. Conclusion: Most with migraine experienced reduction in effectiveness at school and number of days missed from housework. Overall, 47.8% had at least one day affected by headache with an average of 14.3 days disabled by headache and 27.5% of the migraineurs had moderate to severe disability due to migraine.

关键词： Migraine Disability Students Nigerians

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Diabetes and Pre-Diabetes among Adults in an Urban Slum in South East Nigeria

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Journal of Diabetes Mellitus 2018年第4期8卷 131-144页

作者： Birinus Adikaibe Ezeala-Adikaibe Nkeiruka Mbadiwe Celestine Okwara Obinna Onodugo Chinwe Onyekonwu Uchenna Ijoma Oluchi Stella Ekenze Casmir Orjioke Peter Chime Eddy Aneke chidim.a brenda nwatu Ekenechukwu Young Obumneme Anyim Department of Medicine University of Nigeria Teaching Hospital Enugu Nigeria Department of Medicine Enugu State University Teaching Hospital Enugu Nigeria

Background: Despite the rising prevalence of diabetes in Nigeria and sub-Saharan Africa, few studies have assessed the prevalence of prediabetes and diabetes in people with low socioeconomic status or urban slums. Methods: Using the WHO STEP-wise approach to surveillance of noncommunicable diseases, we estimated the prevalence of diabetes and prediabetes among adults 20 years and older living in two urban slums in Enugu south east Nigeria. Diabetes was defined as previous history of diabetes, use of hypoglycemic agents and fasting blood glucose within the diabetes range on two occasions during the survey period. Study duration was 5 months. Results: Out of the 811 individuals invited to the clinic, 605 (74.6%) participants had their fasting blood glucose measured based on the study protocol. The prevalence of diabetes and prediabetes in the population was 11.7% (95% CI;9.2 - 14.3) and 7.6% (95% CI;5.0 - 9.7) respectively. About 54.9% were newly detected and 28.1% of them had normal control. The prevalence of diabetes peaked at 55 - 64 years. The odds ratio for diabetes was significantly higher in participants ≥ 45 years (1.033, 95% CI;1.208 - 3.420), participants with hypertension (0.442, 95% CI;0.257 - 0.762) and stroke (1.638, 95% CI;0.459 - 5.848). Conclusion: There is a relatively high prevalence of diabetes among adults in two urban slums in Enugu. Public health educational measures promoting prevention and early detection of diabetes should be encouraged. Efforts should be made to educate the populace on the need for early detection and treatment.

关键词： Diabetes Nigeria Obesity Prediabetes Epidemiology Urban Dwellers

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Factors Associated with Asymptomatic Proteinuria in Adult Nigerians. A Community-Based Study

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Health 2019年第6期11卷 609-620页

作者： Obinna Onodugo Adikaibe Ezeala-Adikaibe Casmir Orjioke Pauline Nkiruka Onodugo Uchenna Nkemdilim Ijoma Peter Chime Nkeiruka Mbadiwe Chinwe Onyekonwu Obumneme Benneth Anyim Ijeoma Nnenne Obumneme-Anyim Ekenechukwu Young chidim.a brenda nwatu Julius Uwabunkeonye Okoye Monday Ume Nwobodo Department of Medicine University of Nigeria Teaching Hospital Enugu Nigeria Department of Medicine Enugu State University Teaching Hospital Enugu Nigeria Department of Pediatrics University of Nigeria Teaching Hospital Enugu Nigeria

Introduction: Early detection of proteinuria is early detection is a cost-effective method of assessing individuals with and without risk factors for chronic renal disease. Proteinuria is common in adults and may present a clinical challenge in the absence of obvious renal disease or risk factors especially in the tropics. Few studies in Nigeria have assessed the prevalence of proteinuria in adults using the dipstick method. The aim of this study was to document the prevalence of proteinuria among residents of a community in Enugu, south east Nigeria. Methods: This was a cross-sectional descriptive study carried out in an isolated urban slum settlement in Enugu, south east Nigeria. Dipstick testing of freshly voided early morning mid-stream urine samples was done to detect proteinuria. For database management and statistical analyses, SPSS version 23 was used. Results: A total of 262 individuals were recruited for the study, 165 (63%) females and 97 (37%) males. The participants’ age ranged from 18 to 90 years, averaging 43.7 ± 15.5. Trace amounts of protein were detected in urine samples of 225 (85.9%) individuals. Significant proteinuria was detected in 3.8% of the participants and was significantly higher 40 - 49-year-olds (6%). p = 0.02 and 0.02 respectively. Significant correlates of proteinuria were lower diastolic blood pressure and current tobacco use. Lower body mass index weakly correlated with proteinuria. Conclusion: The prevalence of significant early morning proteinuria in a community-based study in Enugu was 3.8%. Significant correlates of proteinuria included low diastolic blood pressure and tobacco use. Community based awareness programs targeted at prevention of chronic renal diseases should be incorporated in public health programs.

关键词： Proteinuria Chronic Renal Disease Risk Factors Nigeria

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Factors Associated with Overweight and Obesity in an Urban Area of South East Nigeria

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Food and Nutrition Sciences 2019年第7期10卷 735-749页

作者： Uchenna Nkemdilim Ijoma Peter Chime Chinwe Onyekonwu Birinus Adikaibe Ezeala-Adikaibe Casmir Orjioke Obumneme Benneth Anyim Obinna Donatus Onodugo Eddy Aneke chidim.a brenda nwatu Ekenechukwu Young Nkeiruka Mbadiwe Oluchi Stella Ekenze Julius Uwabunkeonye Okoye Michael Abonyi Ifeoma Isabella Ulasi Anthony Mbah Pauline Nkiruka Onodugo Department of Medicine University of Nigeria Teaching Hospital Enugu Nigeria Department of Medicine Enugu State University Teaching Hospital Enugu Nigeria

Background: Overweight and obesity present a growing health problem among Africans from all socioeconomic status. In Sub Saharan African, obesity is not only a consequence of overnutrition but possibly from excessive consumption of unbalanced diet dominated by carbohydrates and saturated fats. Characteristics of the distribution of obesity/overweight in Nigeria include its high prevalence along with socioeconomic class and in mid-life. Methods: Using the WHO STEP-wise approach to surveillance of noncommunicable diseases, we conducted a cross-sectional descriptive study of the adult population living in two urban slums in Enugu. The study was carried out in 2013. Statistical analysis was done using SPSS version. Results: A total of 605 (414 women (68.4%) and 191 (31.6%) men were recruited and analysed. The mean body mass index was 25.8 kg/m2 higher in females (26.7 kg/m2) than males (24 kg/m2) p is 29.4% (178/605) and 19.5% (118/605) respectively. There also a modest prevalence of underweight 4% (24/605) among the population. All classes of obesity were significantly more prevalent in females. Significant positive correlates of BMI were: female sex (r = 0.21, p < 0.001), systolic blood pressure (0.25, p < 0.001), DBP (0.27, p < 0.001), fasting blood glucose (0.19, p < 0,001) and positive history of hypertension (0.23, P < 0.001). Negative correlates were physical activity and use of tobacco (0.2 (<0.001) and -0.16 (Conclusion: The prevalence of obesity is relatively high in two urban slums in Enugu and co-exists with a modest rate of underweight. Public health and community-based approaches should be used to tackle these two-opposing social/health problems.

关键词： Obesity Overweight Hypertension Diabetes Nigeria

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