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Racial disparities in the treatment of pancreatic cancer:results from the analysis of a National Database

Journal of Pancreatology 2023年第4期6卷 151-157页

作者： chibueze onyemkpa Danielle Dougherty Sajjaad Samat Tolutope Oyasiji Michael McLeod Department of surgery Michigan State UniversityLansingMIUSA Department of Surgical Oncology McLaren HospitalFlintMIUSA

Background:Pancreatic cancer is the third leading cause of cancer death in the *** have been postulates of racial *** on this,we primarily examined the presence of race,for the diagnosis and treatment of pancreatic ***:A retrospective review was conducted on patients with pancreatic cancers using the Surveillance Epidemiology,and End Results-Medicare *** and multivariate analyses were *** Survival analysis was done using the Kaplan-Meier *** of survival curves was done using the log-rank *** proportional hazards regression model was used to determine independent predictors of *** areas focused on were time interval from diagnosis to treatment,“Predictors of surgery of the primary site,”“Predictors for recommending surgery of the primary site,”“Predictors for oncologic resection,”“Predictors of performance and refusal of surgery of primary site if recommended,”and“Predictors for any other therapy(all therapies excluding surgery)”.Results:A total of 52,951 patients were identified from the database.A total of 24,523 were males and 26,715 were females.A total of 81.9%were Caucasian,10.9%were Black,and 7.2%were other *** was approximately equal distribution of the different stages between both genders.A total of 10.2%of the females were diagnosed at stage I,28.9%,9.3%,and 51.6%at stages I,III,and IV,respectively,compared to males with 8.4%,28.3%,9.2%,and 54.1%for stages I,II,III,and IV,respectively.A total of 9.5%of the Black patients were diagnosed at stage I,24.2%at stage II,10.1%at stage III,and 56.2%at stage IV.A similar distribution was noted in the other *** patients had worse overall survival when compared to Caucasians(P=.004)and other races(P=.001).Conclusion:Compared to Caucasian patients,Black patients with pancreatic cancer had worse overall survival.

关键词： Disparities Pancreas Statistics

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Integrated Geological and Geophysical Mapping for Groundwater Potential Studies at Ekwegbe-Agu and Environs, Enugu State, Nigeria

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Open Journal of Geology 2024年第4期14卷 513-547页

作者： Charles chibueze Ugbor Ugochukwu Kingsley Ogbodo Osita Kelechi Eze Department of Geology University of Nigeria Nsukka Nigeria

The study integrates both the geological and geophysical mapping techniques for groundwater potential studies at Ekwegbe-Agu and the environs, Enugu state, Nigeria for optimal citing of borehole. Located in the Anambra Basin between latitudes 6˚43'N and 6˚47'N and longitudes 7˚28'E and 7˚32'E, it is stratigraphycally underlain by, from bottom to top, the Enugu/Nkporo, Mamu and Ajali Formation respectively, a complex geology that make citing of productive borehole in the area problematic leading to borehole failure and dry holes due to inadequate sampling. The study adopted a field and analytic sampling approach, integrating field geological, electrical resistivity and self-potential methods. The software, SedLog v3.1, InterpexIx1Dv.3, and Surfer v10 were employed for the data integration and interpretation. The result of the geological field and borehole data shows 11 sedimentary facies consisting of sandstone, shales and heterolith of sandstone/shale, with the aquifer zone mostly prevalent in the more porous sand-dominated horizons. Mostly the AK and HK were the dominant curve types. An average of 6 geo-electric layers were delineated across all transects with resistivity values ranging from 25.42 - 105.85 Ωm, 186.38 - 3383.3 Ωm, and 2992 - 6286.4 Ωm in the Enugu, Mamu and Ajali Formations respectively. The resistivity of the main aquifer layer ranges from 1 to 500 Ωm. The aquifer thickness within the study area varies between 95 and 140 m. The western and northwestern part of the study area which is underlain mainly by the Ajali Formation showed the highest groundwater potential in the area and suitable for citing productive boreholes.

关键词： Seismic Ekwegbe-Agu Groundwater Resistivity Field Mapping Borehole Logging

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Simultaneous Waveform Inverse Modelling for Litho-Fluid Prediction in an Old Marginal, “Agbbo”Field, Onshore Niger Delta, Nigeria

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Journal of Geoscience and Environment Protection 2024年第5期12卷 40-59页

作者： Charles chibueze Ugbor Peter Ogobi Odong Chukwuemeka Austine Okonkwo Department of Geology University of Nigeria Nsukka Nigeria Department of Geology and Mining Enugu State University of Science and Technology Enugu Nigeria

Simultaneous waveform inversion was used to predict lithofacies and fluid type across the field. Very often, characterizing reservoirs in terms of lithology and fluid type using conventional methods is replete with uncertainties, especially in marginal fields. An approach is employed in this study that integrated rock physics and waveform inverse modelling for lithology and fluid-type characterization to appropriately identify potential hydrocarbon saturated zones and their corresponding lithology. Seismic and well-log data were analyzed using Hampson Russel software. The method adopted includes lithofacies and fluid content analysis using rock physics parameters and seismic simultaneous inverse modelling. Rock physics analysis identified 2 broad reservoirs namely: HDZ1 and HDZ2 reservoirs. Results from the inverse modelling showed that low values of acoustic impedance from 19,743 to 20,487 (ft/s)(g/cc) reflect hydrocarbon-bearing reservoirs while medium to high values shows brine and shale respectively, with brine zone ranging from 20,487 to 22,531 (ft/s)(g/cc) and shale above 22,531 (ft/s)(g/cc). Two lithofacies were identified from inversion analysis of Vp/Vs and Mu-Rho, namely: sand and shale with VpVs 1.95 values respectively. Mu-Rho > 12.29 (GPa)(g/cc) and <12.29 (GPa) (g/cc) represent sand and shale respectively. From 3D volume, it was observed that a high accumulation of hydrocarbon was observed to be saturated at the north to the eastern part of the field forming a meandering channel. Sands were mainly distributed around the northeastern to the southwestern part of the field, that tends to be away from Well 029. This was also validated by the volume of rigidity modulus (Mu-Rho) showing high values indicating sands fall within the northeastern part of the field.

关键词： Simultaneous Waveform Inversion Lithofacies Fluid Type Rock Physics Hydrocarbon Acoustic Impedance Mu-Rho Reservoir

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Evaluation of Hydrocarbon Potential Using AVO Analysis in the FORMAT Field, Niger Delta Basin, Nigeria

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Open Journal of Geology 2024年第3期14卷 403-430页

作者： Charles chibueze Ugbor Onyebuchi Samuel Onyeabor Ifeanyi Celestine Ugwuoke Department of Geology University of Nigeria Nsukka Enugu State Nigeria

The study involved the evaluation of the hydrocarbon potential of FORMAT Field, coastal swamp depobelt Niger delta, Nigeria to obtain a more efficient reservoir characterization and fluid properties identification. Despite advances in seismic data interpretation using traditional 3D seismic data interpretation, obtaining adequate reservoir characteristics at the finest level had proved very challenging with often disappointing results. A method that integrates the amplitude variation with offfset (AVO) analysis is hereby proposed to better illuminate the reservoir. The Hampson Russell 10.3 was used to integrate and study the available seismic and well data. The reservoir of interest was delineated using the available suite of petrophysical data. This was marked by low gamma ray, high resistivity, and low acoustic impedance between a true subsea vertical depth (TVDss) range of 10,350 - 10,450 ft. The AVO fluid substitution yielded a decrease in the density values of pure gas (2.3 - 1.6 g/cc), pure oil (2.3 - 1.8 g/cc) while the Poisson pure brine increased (2.3 to 2.8 g/cc). Result from FORMAT 26 plots yielded a negative intercept and negative gradient at the top and a positive intercept and positive gradient at the Base which conforms to Class III AVO anomaly. FORMAT 30 plots yielded a negative intercept and positive gradient at the top and a positive intercept and negative gradient at the Base which conforms to class IV AVO anomaly. AVO attribute volume slices decreased in the Poisson ratio (0.96 to - 1.0) indicating that the reservoir contains hydrocarbon. The s-wave reflectivity and the product of the intercept and gradient further clarified that there was a Class 3 gas sand in the reservoir and the possibility of a Class 4 gas sand anomaly in that same reservoir.

关键词： AVO Analysis Hydrocarbon Potential Fluid Properties Reservoir Characterization Petrophysical Data Hampson Russel

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Artificial Neural Network and Fuzzy Logic Based Techniques for Numerical Modeling and Prediction of Aluminum-5%Magnesium Alloy Doped with REM Neodymium

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International Journal of Nonferrous Metallurgy 2024年第1期11卷 1-19页

作者： Anukwonke Maxwell Chukwuma chibueze Ikechukwu Godwills Cynthia C. Nwaeju Osakwe Francis Onyemachi Department of Metallurgical and Materials Engineering Nnamdi Azikiwe University Awka Nigeria Department of Mechanical Engineering Nigeria Martine University Okerenkoko Nigeria

In this study, the mechanical properties of aluminum-5%magnesium doped with rare earth metal neodymium were evaluated. Fuzzy logic (FL) and artificial neural network (ANN) were used to model the mechanical properties of aluminum-5%magnesium (0-0.9 wt%) neodymium. The single input (SI) to the fuzzy logic and artificial neural network models was the percentage weight of neodymium, while the multiple outputs (MO) were average grain size, ultimate tensile strength, yield strength elongation and hardness. The fuzzy logic-based model showed more accurate prediction than the artificial neutral network-based model in terms of the correlation coefficient values (R).

关键词： Al-5%Mg Alloy Neodymium Artificial Neural Network Fuzzy Logic Average Grain Size and Mechanical Properties

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In Search of Portable Water Supplies within a Brine and Mine Water-Invaded Region for Serving Some Communities around Ishiagu, Afikpo and Environs in Abakaliki Basin, Southeast Nigeria

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International Journal of Geosciences 2023年第2期14卷 209-225页

作者： Charles chibueze Ugbor Department of Geology University of Nigeria Nsukka Nigeria

The study investigates the hydrogeochemical characteristics of some towns in the Abakaliki Basin, comprising, Ishiagu, Aka Eze, Amaseri, Afikpo and Okposi communities, with the aim of sourcing for portable water in the area. The basin is underlain by Albian sediments, essentially shales, in the lowlands, which were affected by low-grade metamorphism that had produced slates. The highlands comprise basic intrusives from episodes of magmatism and metallic ore mineralisation. Injection of brines into the aquifer system and low, seasonal aquifer recharge from rainfall results in poor water quality in the area. The study analyzes the geochemical distribution in water sources in the area and identifies sources of pollutants to guide the better choice of portable water. Results of hydrogeochemical analysis of both surface and groundwater from the communities were compared with World Health Organization to identify portable water locations in the area. While the salt lake at Okposi is the main source of brine intrusion in the study area, the Pb/Zn mine at Ishiagu is the main source of mine-water pollution in the study area. Most chemical parameters, (especially Cl-, Na+, Ca2+, Mg2+, SO42-, HCO3-) maintain high concentrations within the salt lake area, with the values declining away from the salt lake. The main anthropogenic source of pollution in the area, especially at Ishiagu, is the indiscriminate surface mining of lead-zinc without proposer waste management practices. Possible sourcing for portable water in the study area includes a deep borehole at Ishiagu, away from lead-zinc intrusives. At the Okposi axis, searching for portable water in boreholes should target shallower aquifers that do not communicate with the deeper-seated brine zones, likewise targeting zones farther away from these brine-invaded areas. A controlled pumping rate could potentially ensure that the cone of depres

关键词： Abakaliki Basin Portable Water Brine Aquifer Salt Lake Pollution Desaline Water

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Evaluation of Hydrocarbon Reservoir in the “SIMA” Field of Niger Delta Nigeria from Interpretation of 3D Seismic and Petrophysical Log Data

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International Journal of Geosciences 2023年第1期14卷 94-107页

作者： Charles chibueze Ugbor Department of Geology University of Nigeria Nsukka Nigeria

3D seismic and petrophysical log data interpretation of reservoir sands in “SIMA” Field, onshore Niger Delta has been undertaken in this study to ascertain the reservoir characteristics in terms of favourable structural and petrophysical parameters suitable for hydrocarbon accumulation and entrapment in the field. Horizon and fault interpretation were carried out for subsurface structural delineation. In all, seven faults (five normal and two listric faults) were mapped in the seismic section. These faults were major structure building faults corresponding to the growth and antithetic faults in the area within the well control. The antithetic fault trending northwest-southeast and the normal fault trending northeast-southwest on the structural high in the section act as good trapping mechanisms for hydrocarbon accumulations in the reservoir. From the manual and auto-tracking methods applied, several horizons were identified and mapped. The section is characterized by high amplitude with moderate-to-good continuity reflections appearing parallel to sub-parallel, mostly disturbed by some truncations which are more fault related than lithologic heterogeneity. The southwestern part is, however, characterized by low-to-high or variable amplitude reflections with poor-to-low continuity. Normal faults linked to roll-over anticlines were identified. Some fault truncations were observed due to lithologic heterogeneity. The combination of these faults acts as good traps for hydrocarbon accumulations in the reservoir. Reservoir favourable petrophysical qualities, having average NTG, porosity, permeability and water saturation of 5 m, 0.20423, 1128.219 kD and 0.458 respectively.

关键词： Seismic Interpretation Hydrocarbon Accumulation Porosity Reservoir Niger Delta Petrophysical Properties Faults Horizons

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Assessment of the Spectral Decomposition Techniques in the Evaluation of Hydrocarbon Potential of “BOMS” Field, Coastal Swamp Niger Delta, Nigeria

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International Journal of Geosciences 2023年第7期14卷 655-676页

作者： Charles chibueze Ugbor Onyebuchi Samuel Onyeabor Department of Geology University of Nigeria Nsukka Nigeria

This study employs the different approaches of the spectral decomposition techniques to evaluate the hydrocarbon potential of the reservoir and analyse to determine the most efficient spectral decomposition technique with better resolution using the “BOMS” Field, coastal swamp depobelt Niger Delta, Nigeria. A good number of drilled wells have failed both in the Niger Delta Basin and other basins due to a poor understanding of the reservoir properties in advance of drilling and identifying the best approach will help to minimize this risk. Seismic and well logs data together with the Hampson Russel 10.3 software were used for the study. The target reservoirs were identified from the suite of well logs at the horizons with low gamma ray, high resistivity, and low acoustic impedance between TVD (ft) of 10,350 - 10,450 ft. The analysis of the amplitude spectrum of the seismic data revealed that the distortion of interest lies between 5 - 60 Hz. Seismic data were then spectrally decomposed into several frequencies such as low frequency (15 Hz), mid-frequency (31 Hz), and high frequency (46 Hz) where distortions were observed. Time- frequency slices of 15 Hz and 23 Hz provided clearer events (potential hydrocarbon sand) indicated by high amplitude envelope (2200 - 2400) and amplitude anomalies. While the amplitude dropped in the mid-frequency (31 Hz), the high amplitude envelope and the high energy completely disappeared in the high (46 Hz) time-frequency slice. A comparison of the Short- time Fourier transform and the Basic Pursuit algorithm revealed that the Basic Pursuit provided a better resolution of the reservoir characteristics than the former. The Red, Green and Blue (RGB) colour blending model indicated that the channel was consistent with the low-frequency section and amplitude anomaly.

关键词： Amplitude Hydrocarbon Evaluation Spectral Analysis Reservoir Sand Basic Pursuit Convolution

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Estimation of Aquifer Transmissivity Using Dar Zarrouk Parameters at Ogbozara-Ekwegbe-Agu and the Environ, Enugu State, Nigeria

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Open Journal of Geology 2023年第8期13卷 783-805页

作者： Charles chibueze Ugbor Ugochukwu Kingsley Ogbodo Department of Geology University of Nigeria Nsukka Nigeria

This study was undertaken to determine the hydrologic properties of the aquifer materials at Ogbozara-Opi/Ekwegbe-Agu and environs by the estimation of the aquifer transmissivity using Dar Zarrouk parameters. The study area lies in the Anambra basin and is underlain, from bottom to top, by 3 prominent geologic formations;Enugu Formation, Mamu Formation and Ajali Formation respectively. A total of 19 sounding stations were occupied within the study area using the Ohmega resistivity meter. The VES data were interpreted using the conventional partial curve matching technique to obtain initial model parameters which were later used as input data for computer iterative modelling using the Interpex software. These analyses were further combined with information from two existing boreholes in the study area to estimate aquifer hydraulic parameters using Dar-Zarrouk parameters. The layer parameters thus obtained revealed that the dominant curve type obtained from the different formations is the AK curve type followed by the HK curve type. An average of 6 geo-electric layers were delineated across all transect taken with resistivity values ranging from 25.42 - 105.85 Ωm, 186.38 - 3383.3 Ωm and 2992.3 - 6286.4 Ωm in the Enugu, Mamu and Ajali Formations respectively. Results of the study revealed the aquifer resistivity in the study area ranges from 1 - 500 Ωm. The depth to the water table range from 13 - 208 m with a mean value of 76.05, while aquifer thickness varies between 95 and 140 m with a mean value of 102.89 m. The values of the Dar-Zarrouk parameters revealed that the transverse resistance varies between −10,000 - 170,000 Ωm2, while the longitudinal conductance varies from 0.1 - 1 to 1.9 Ω - 1. Similarly, the hydraulic conductivity in the area ranges from 5 to 50 m/day, while the transmissivity values range from 1000 to 14,000 m2/day.

关键词： Aquifer Dar Zarrouk Parameters VES Transmissivity Conductance

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The ALMA-QUARKS Survey.Ⅱ.The ACA 1.3 mm Continuum Source Catalog and the Assembly of Dense Gas in Massive Star-Forming Clumps

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Research in Astronomy and Astrophysics 2024年第6期24卷 119-139页

作者：许峰玮 Ke Wang Tie Liu Lei Zhu Guido Garay Xunchuan Liu Paul Goldsmith Qizhou Zhang Patricio Sanhueza Shengli Qin Jinhua He Mika Juvela Anandmayee Tej Hongli Liu Shanghuo Li Kaho Morii Siju Zhang Jianwen Zhou Amelia Stutz Neal JEvans Kee-Tae Kim Shengyuan Liu Diego Mardones Guangxing Li Leonardo Bronfman Ken’ichi Tatematsu Chang Won Lee Xing Lu Xiaofeng Mai Sihan Jiao James O.chibueze Keyun Su Viktor L.Tóth Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China Department of Astronomy School of PhysicsPeking UniversityBeijing 100871China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China Chinese Academy of Sciences South America Center for Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Departamento de Astronomía Universidad de ChileLas Condes7591245 SantiagoChile Jet Propulsion Laboratory California Institute of Technology4800 Oak Grove DrivePasadena CA 91109USA Center for Astrophysics|Harvard&Smithsonian 60 Garden StreetCambridgeMA 02138USA National Astronomical Observatory of Japan National Institutes of Natural Sciences2-21-1 OsawaMitakaTokyo 181-8588Japan Astronomical Science Program The Graduate University for Advanced StudiesSOKENDAI2-21-1 OsawaMitakaTokyo 181-8588Japan School of Physics and Astronomy Yunnan UniversityKunming 650091China Yunnan Observatories Chinese Academy of SciencesKunming 650216China Department of Physics University of HelsinkiPO Box 64FI-00014 HelsinkiFinland Indian Institute of Space Science and Technology Thiruvananthapuram 695547KeralaIndia Max Planck Institute for Astronomy Königstuhl 17D-69117 HeidelbergGermany Department of Astronomy Graduate School of ScienceThe University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-0033Japan Max-Planck-Institut für Radioastronomie Auf dem Hügel 6953121 BonnGermany Departamento de AstronomÂıa Universidad de ConcepcionCasilla 160-CConcepci onChile Department of Astronomy The University of Texas at AustinTexas 78712-1205USA Korea Astronomy and Space Science Institute 776 Daedeokdae-roYuseong-guDaejeon 34055Republic of Korea Institute of Astronomy and Astrophysics Academia SinicaRoosevelt RoadTaipei 10617TaiwanChina South-Western Institute for Astronomy Research Yunnan UniversityKunming 650091China Korea Astronomy and Space Science Institute 776 Daedeok-daeroYuseong-guDaejeon 34055Republic of

Leveraging the high resolution,sensitivity,and wide frequency coverage of the Atacama Large Millimeter/submillimeter Array(ALMA),the QUARKS survey,standing for“Querying Underlying mechanisms of massive star formation with ALMA-Resolved gas Kinematics and Structures”,is observing 139 massive starforming clumps at ALMA Band 6(λ~1.3 mm).This paper introduces the Atacama Compact Array(ACA)7 m data of the QUARKS survey,describing the ACA observations and data *** multiwavelength data,we provide the first edition of QUARKS atlas,offering insights into the multiscale and multiphase interstellar medium in high-mass star *** ACA 1.3 mm catalog includes 207 continuum sources that are called ACA *** gas kinetic temperatures are estimated using three formaldehyde transitions with a non-LTE radiation transfer model,and the mass and density are derived from a dust emission *** ACA sources are massive(16–84 percentile values of 6–160 M_(⊙)),gravity-dominated(M∝R^(1.1))fragments within massive clumps,with supersonic turbulence(M>1)and embedded star-forming *** find a linear correlation between the masses of the fragments and the massive clumps,with a ratio of 6%between the *** considering fragments as representative of dense gas,the ratio indicates a dense gas fraction(DGF)of 6%,although with a wide scatter ranging from 1%to 10%.If we consider the QUARKS massive clumps to be what is observed at various scales,then the size-independent DGF indicates a self-similar fragmentation or collapsing mode in protocluster *** the ACA data over four orders of magnitude of luminosity-to-mass ratio(L/M),we find that the DGF increases significantly with L/M,which indicates clump evolutionary *** observed a limited fragmentation at the subclump scale,which can be explained by a dynamic global collapse process.

关键词： stars:formation ISM:kinematics and dynamics ISM:clouds stars:protostars

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