检索结果-南通市图书馆

世界核心医学期刊文摘（皮肤病学分册） 2005年第8期1卷 53-53页

作者： Chia C.Y. chibnall j. E. Siegfried 潘敏 Dr. Kids Dermatology 621 S New Ballas Rd St. Louis MO 63141 United States

Obj.ctive: To determine whether patients with moderate to severe acne who were treated with isotretinoin experienced significant increases in depressive symptoms over a 3- to 4- month period compared with patients who received conservative acne therapy. Design: Cohort study. Setting: Hospital- affiliated and community- based clinics in St Louis, Mo. Participants: One hundred thirty- two subj.cts aged 12 to 19 years with moderate to severe acne. Main Outcome Measures: Depressive symptoms were assessed using the Center for Epidemiological StudiesDepressionScale(CES- D),astandardizedself- reported instrument. Mean CES- D scores were compared between treatment groups, as were the prevalence and incidence of scores suggestive of clinically significant depression (CES- D score >16). Results: A total of 101 subj.cts completed the study. At follow- up, CES- D scores (adj.sted for baseline CES- D score and sex of patient) suggestive of clinically significant depression were no more prevalent in the isotretinoin group than in the conservative therapy group. Similarly, the incidence (new onset) of depressive symptoms suggestive of clinical significance also was not significantly different between the treatment groups. Conclusions: The use of isotretinoin in the treatment of moderate- severe acne in adolescents did not increase symptoms of depression. On the contrary, treatment of acne either with conservative therapy or with isotretinoin was associated with a decrease in depressive symptoms.

关键词：重度痤疮队列研究郁症附属医院保守治疗组圣路易斯密苏里州流行病学研究自我报告样地

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：