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Simple procedure for assessing diffuse subarachnoid hemorrhage successfully created using filament perforation method in mice

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Animal Models and Experimental Medicine 2024年第1期7卷 77-81页

作者： Tatsushi Mutoh Ryota Tochinai Hiroaki Aono Masayoshi Kuwahara Yasuyuki taki Tatsuya Ishikawa Department of Surgical Neurology Research Institute for Brain and Blood VesselsAkita Cerebrospinal and Cardiovascular CenterAkitaJapan Department of Aging Research and Geriatric Medicine Institute of DevelopmentAging and CancerTohoku UniversitySendaiJapan Department of Veterinary Pathophysiology and Animal Health Graduate School of Agriculture and Life SciencesThe University of TokyoTokyoJapan

The murine model of subarachnoid hemorrhage(SAH)is a valuable experimental tool for investigating molecular and cellular mechanisms,and the endovascular filament perforation technique can be used to simulate prominent pathophysiological features observed after human SAH;however,current validation methods for assessing an appropriate SAH model are ***,we introduce a simple procedure for se-lecting a mouse model of diffuse *** was induced in 24 mice using a standard filament perforation *** confirming survival at 24 h,SAH was scored 0-1 based on T2*-weighted images on whole-brain magnetic resonance imaging(MRI)and visual surveillance of the cisterna magna(CM)through the dura *** CM-based SAH grading correlated well with a reference parameter defined by extracted brain(r^(2)=0.53,p<0.0001).The receiver operating characteristic curve revealed a sensi-tivity of 85%and a specificity of 91%for detecting diffuse SAH,with a similar area under the curve(0.89±0.06[standard error of the mean])as the MRI-based grading(0.72±0.10,p=0.12).Our data suggest that confirming an SAH clot in the CM is a valuable way to select a clinically relevant diffuse SAH model that can be used in future experimental studies.

关键词： cisterna magna clot distribution filament perforation mouse model subarachnoid hemorrhage

Vaccination effect on a stochastic epidemic model with healing and relapse

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International Journal of Biomathematics 2024年第1期17卷 29-59页

作者： M.M.Abdeslami L.Basri M.El Fatini I.Sekkak R.taki Laboratory of Partial Differential Equations Spectral Algebra and Geometry Department of Mathematics Faculty of Sciences Ibn Tofail UniversityBP 133KénitraMorocco Centre de Recherche en Sante Publique Montréal(Québec)H3N 1X9 Canada Departement de Medecine Sociale et Preventive Ecole de SantéPublique de I'Universitéde Montreal 101Avenue du ParcMontréal(Quebec)H3N 1X9Canada EST Sidi Bennour Chouaib Doukkali UniversityEl JadidaMorocco

In this work,we consider a stochastic epidemic model with vaccination,healing and *** prove the existence and the uniqueness of the positive *** establish sufficient conditions for the extinction and the persistence in mean of the stochastic ***,we also establish sufficient conditions for the existence of ergodic stationary distribution to the model,which reveals that the infectious disease will *** graphical illustrations of the approximate solutions of the stochastic epidemic model have been performed.

关键词： Stochastic epidemic model with relapse and healing vaccination extinction persistence in mean Markov semigroup stationary distribution

Modeling the energy gain reduction due to shadow in flat-plate solar collectors;Application of artificial intelligence

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Artificial Intelligence in Agriculture 2021年第1期5卷 185-195页

作者： Morteza taki Rouhollah Farhadi Department of Agricultural Machinery and Mechanization Engineering Agricultural Sciences and Natural Resources University of KhuzestanP.O.Box:***MollasaniIran

Energy lost due to shadow in the absorber plate of solar collectors can decrease the solar energy *** some studies,mathematical modeling was applied for calculating the energy gain reduction due to shadow in flatplate solar *** this study,ANN method was developed for modeling the energy gain *** Perceptron(MLP)with one hidden layer and a range of neurons(5–30)by two training algorithms(LM and BR)and tangent sigmoid activation function(TanSig)were used by help of K-fold cross validation *** the first section,six set of solar collector dimensions were used(1×1;1×1.5;1×2;1.5×1.5;1.5×2 and 2×2).In the second section all the range of dimensions were used as the *** results of the first section showed thatMLPwith BR training algorithm can predict the energy gain reductionwith minimumMAPE and RMSE in all the *** best results related to(1.5×1.5)dimension that achieved a MAPE of 0.15±0.09%and RMASE of 4.42±2.43 KJm−2 year−1,*** results of the second section indicated that BR is a better training algorithm than *** MAPE and R2 factors for the best topology(5-27-1)were 0.0610±0.0051%and 0.9999±0.0001,*** results of the sensitivity analysis showed that height has the biggest impact on total energy gain reduction due to shadow in flat-plate solar ***,the results of this study indicated that by using ANN and decrease the energy lost,the efficiency of solar collectors can be increased in all applications such as industry and agriculture.

关键词： Multilayer perceptron Optimization Energy Sensitivity analysis

Intraspinal transplantation of motoneuron-like cell combined with delivery of polymer-based glial cell line-derived neurotrophic factor for repair of spinal cord contusion injury

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Neural Regeneration Research 2014年第10期9卷 1003-1013页

作者： Alireza Abdanipour taki Tiraihi Taher Taheri Shefa Neuroscience Research Center at Khatam Al-Anbia Hospital

To evaluate the effects of glial cell line-derived neurotrophic factor transplantation combined with adipose-derived stem cells-transdifferentiated motoneuron delivery on spinal cord con-tusion injury, we developed rat models of spinal cord contusion injury, 7 days later, injected adipose-derived stem cells-transdifferentiated motoneurons into the epicenter, rostral and caudal regions of the impact site and simultaneously transplanted glial cell line-derived neuro-trophic factor-gelfoam complex into the myelin sheath. Motoneuron-like cell transplantation combined with glial cell line-derived neurotrophic factor delivery reduced cavity formations and increased cell density in the transplantation site. The combined therapy exhibited superior promoting effects on recovery of motor function to transplantation of glial cell line-derived neurotrophic factor, adipose-derived stem cells or motoneurons alone. These ifndings suggest that motoneuron-like cell transplantation combined with glial cell line-derived neurotrophic factor delivery holds a great promise for repair of spinal cord injury.

关键词： nerve regeneration spinal cord injury adipose-derived stem cells glial cell line-derived neurotrophic factor motoneurons cell transplantation neurotrophic factor spinal cord contusion injury neural regeneration

A framework approach to the design of energy efficient residential buildings in Nigeria

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Energy and Built Environment 2022年第3期3卷 384-397页

作者： Ekele Thompson Ochedi Ahmad taki Department of Architectural Technology School of Environmental TechnologyKogi State PolytechnicP.M.B.1101LokojaNigeria Director of Architecture Research Institute Leicester School of ArchitectureDe Montfort UniversityLeicester LE19BHUK

The main objective of the Nigerian building sector working on achieving energy efficiency is to decrease energy demand of buildings and thereby reduce the negative implications of urban development and poor energy infras-tructure on people’s *** of the key strategies being adopted for substantial reduction of energy demand in the Building Energy Efficiency Guide for Nigeria is the bioclimatic architectural design ***,in-telligent design of buildings,especially the building envelope,can considerably improve energy efficiency and help to realize heating and cooling *** aim of this paper is to promote and encourage sustainable build-ing development in Nigeria by developing a systematic and context-based framework for the design of energy efficient residential *** study adopted a mixed method approach of interviews with 12 architects and 22 ***,measurements and observational surveys of 22 existing buildings that fit into three distinct building typologies were *** existing buildings were investigated using a building simu-lation approach to compare their performances,especially in terms of thermal *** data collected was analysed using content analysis,descriptive statistics analysis,and *** interviews with architects and householders showed enormous potential to reduce residential buildings’energy *** achieve this,the interviewees emphasized the need for strong collaboration between all stakeholders in the building ***,observational surveys,and case studies of existing buildings confirmed that thermal discomfort in residential buildings and challenges with building design,have a significant effect on the building occupants’*** research developed a framework for the design of energy-efficient residential building,which is expected to enhance sustainability,particularly in the building *** framework was produced based on the findings from the re

关键词： Framework Energy consumption Energy efficient buildings Simulation Case study Lokoja/Nigeria

Finite Order Batalin-Fradkin-Tyutin Method for Chiral Bosons in Non-commutative Space

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Communications in Theoretical Physics 2010年第12期54卷 1067-1070页

作者： Monemzadeh Majid Nikoofard Vahid taki Mehran Department of Physics University of Kashan

The recently improved finite order BFT Hamiltonian embedding method is applied to the two dimensional chiral bosons in non-commutative space. It is then systematically converted to a first class constraint model. Performing the momentum integrations, the corresponding fully gauge symmetry Lagrangian as well as its partition function in phase space are obtained.

关键词： constrained systems BFT approach

Solvability of the Nonlocal Inverse Parabolic Problem and Numerical Results

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Computer Systems Science & Engineering 2022年第3期40卷 1109-1126页

作者： M.J.Huntul taki-Eddine Oussaeif Department of Mathematics College of ScienceJazan UniversityJazanSaudi Arabia Department of Mathematics and Informatics Larbi Ben M’hidi UniversityOum El BouaghiAlgeria

In this paper,we consider the unique solvability of the inverse problem of determining the right-hand side of a parabolic equation whose leading coefficient depends on time variable under nonlocal integral overdetermination *** obtain sufficient conditions for the unique solvability of the inverse *** existence and uniqueness of the solution of the inverse parabolic problem upon the data are established using the fixed point *** inverse problem appears extensively in the modelling of various phenomena in engineering and *** example,seismology,medicine,fusion welding,continuous casting,metallurgy,aircraft,oil and gas production during drilling and operation of *** addition,the numerical solution of the inverse problem is studied by using the Crank-Nicolson finite difference method together with the Tikhonov regularization to find a stable and accurate approximate solution of finite *** resulting nonlinear system of parabolic equation is solved computationally using the MATLAB subroutine *** analytical and numerically simulated noisy input data are *** root mean square error values for various noise levels for both continuous and discontinuous time-dependent heat source term are *** results presented for two examples show the efficiency of the computational method and the accuracy and stability of the numerical solution even in the presence of noise in the input ***,the choice of the regularization parameter is also discussed based on the trial and error technique.

关键词： Inverse problem nonlocal integral condition fixed point theorem Tikhonov regularization nonlinear optimization

Solar thermal simulation and applications in greenhouse

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Information Processing in Agriculture 2018年第1期5卷 83-113页

作者： Morteza taki Abbas Rohani Mostafa Rahmati-Joneidabad Department of Agricultural Machinery and Mechanization Ramin Agriculture and Natural Resources University of KhuzestanMollasaniIran Department of Biosystems Engineering Faculty of AgricultureFerdowsi University of MashhadIran Department of Horticultural Science Faculty of AgricultureRamin Agriculture and Natural Resources University of KhuzestanMollasaniIran

In this study,a comprehensive review focusing on key strategies of energy saving technologies based on simulation of heat and mass transfer and also artificial intelligent for climate controlling is *** the brief and concise assessment of existing greenhouse systems in terms of their role in total energy consumption;effective shape and structure,energy-efficient and new technologies are analyzed in detail for potential utilization in greenhouses for notable reductions in energy consumption and also go toward the *** technologies considered within the scope of this research are mainly renewable and sustainable based solutions such as photovoltaic(PV)modules,solar thermal(T)collectors,hybrid PV/T collectors and systems,phase change material(PCM)and underground based heat storage techniques,energy-efficient heat pumps,alternative facade materials for better thermal insulation and power *** findings from the research clearly reveal that up to 70%energy saving can be achieved through appropriate retrofit of conventional *** of solar greenhouses in Europe is more popular than *** some countries in Asia such as Iran,it is very restrict to invest on renewable projects because of cheap fossil *** it is recommended beside of investments by private investors,the Iranian government should also invest in the extension of solar energy in greenhouse by setting up a specialized agency or contracting *** should target the modeling and design the best shape of solar greenhouse for all agricultural areas to receive the maximum solar radiation and decrease the need of fossil fuels.

关键词： Agricultural greenhouse Sustainability Heat and mass transfer Modeling and simulation

Cell-based allometry:an approach for evaluation of complexity in morphogenesis

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Quantitative Biology 2023年第2期11卷 183-203页

作者： Ali Tarihi Mojtaba Tarihi taki Tiraihi Department of Computer Engineering Faculty of Computer Science and EngineeringShahid Behshti UniversityTehran 19839-69411Iran Department of Computer Engineering Sharif University of TechnologyTehran 11365-11155Iran Department of Anatomical Sciences School of Medical SciencesTarbiat Modares UniversityTehran 14117-13116Iran

Background:Morphogenesis is a complex process in a developing animal at the organ,cellular and molecular *** this investigation,allometry at the cellular level was ***:Geometric information,including the time-lapse Cartesian coordinates of each cell's center,was used for calculating the allometric coefficients.A zero-centroaxial skew-symmetrical matrix(CSSM),was generated and used for constructing another square matrix(basic square matrix:BSM),then the determinant of BSM was calculated(d).The logarithms of absolute d(Lad)of cell group at different stages of development were plotted for all of the cells in a range of development stages;the slope of the regression line was estimated then used as the allometric ***,the lineage growth rate(LGR)was also calculated by plotting the Lad against the logarithm of the *** complexity index at each stage was *** method was tested on a developing Caenorhabditis elegans ***:We explored two out of the four first generated blastomeres in *** *** ABp and EMS lineages show that the allometric coefficient of ABp was higher than that of EMS,which was consistent with the complexityindexas well ***:The conclusion of this study is that the complexity of the differentiating cells in a developing embryo can be evaluated by allometric scaling based on the data derived from the Cartesian coordinates of the cells at different stages of development.

关键词： embryogenesis allometry complexity C.elegans bioinformatics skew matrix morphogenesis