检索结果-南通市图书馆

Asian Pacific Journal of Tropical Medicine 2013年第8期6卷 589-594页

作者： Segun Isaac Oyedeji Henrietta Oluwatoyin Awobode chiaka anumudu Jrgen Kun Department of Biotechnology Bells University of Technology Parasitology Unit Department of Zoology University of Ibadan Institute of Tropical Medicine Eberhard Karls University

Objective: To characterize the genetic diversity of Plasmodium falciparum ( P. falciparum ) field isolates in children from Lafia, North-central Nigeria, using the highly polymorphic P. falciparum merozoite surface protein 2 (MSP-2) gene as molecular marker. Methods: Three hundred and twenty children were enrolled into the study between 2005 and 2006. These included 140 children who presented with uncomplicated malaria at the Dalhatu Araf Specialist Hospital, Lafia and another 180 children from the study area with asymptomatic infection. DNA was extracted from blood spot on filter paper and MSP-2 genes were genotyped using allele-specific nested PCR in order to analyze the genetic diversity of parasite isolates. Results: A total of 31 and 34 distinct MSP-2 alleles were identified in the asymptomatic and uncomplicated malaria groups respectively. No difference was found between the multiplicity of infection in the asymptomatic group and that of the uncomplicated malaria group ( P >0.05). However, isolates of the FC27 allele type were dominant in the asymptomatic group whereas isolates of the 3D7 allele type were dominant in the uncomplicated malaria group. Conclusions: This study showed a high genetic diversity of P. falciparum isolates in North-central Nigeria and is comparable to reports from similar areas with high malaria transmission intensity.

关键词： Malaria Plasmodium falciparum MSP-2 Genetic diversity PCR North-central Nigeria

Pancreatic islet regeneration and some liver biochemical parameters of leaf extracts of Vitex doniana in normal and streptozotocin-induced diabetic albino rats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2014年第2期4卷 124-130页

作者： Okpe Oche Ibrahim Sani Njoku Godwin chiaka Ndidi Uche Samuel Atabo Samuel Department of Biochemistry Ahmadu Bello UnirersityZariaNigeria

Objective:To test two water soluble extracts(aqueous and ethanolic) obtained from the leaves of Vitex doniana in normal and streptozotocin-induced diabetic rats for their effects on pancreatic endocrine tissues and serum marker enzymes for a period of 21 ***:A total of 55 rate divided into 11 groups of 5 rats each were assigned into diabetic and non-diabetic- groups and fallowed by a daily administration of ethanolic and aqueous extracts for21 *** 1 was the normal control while group 7 was treated with standard ***:The histopathological studies of the diabetic rats indicated increase in the volume density of islets,percent of β-cells and size of islet in the groups that received the plant extracts,which suggested regeneration of β-cells along with p-eells repairs,as compared with the non-treated diabetic control which showed complete degeneration of the islet *** was significant reduction(P0.01) in the serum activities of marker enzymes was observed for non-diabetic treated *** of total bilirubin,direct bilirubin and unconjugated bilirubin showed that diabetic control group was significantly higher(P0.01) in total bilirubin and direct bilirubin compared with the normal ***:This herbal therapy appears to bring about repair/regeneration of the endocrine pancreas and hepatic cells protection in the diabetic rat.

关键词： Vitex doniana Pancreatic islet Marker enzymes Diabetes Hepatoprotection

A Synoptic Review of Mineralogical and Chemical Characteristics of Clays in the Southern Part of Nigeria

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Ecology 2021年第2期3卷 32-45页

作者： Moses Oghenenyoreme Eyankware Christopher Ogwah Joy chiaka Ike Department of Geology Faculty of SciencesEbonyi State UniversityAbakaliki.P.M.B.053Ebonyi StateNigeria Geomoses Consultancy Limited Warri Delta StateNigeria Department of Energy and Petroleum Studies Novena UniversityOgume Delta StateNigeria

This paper reviews the mineralogical and chemical characteristics of clays found in southern part of Nigeria,with a view to determine its *** usability of clays,depends on its chemical and mineralogical charactertics,the end product of clay after it is been processed is also based on it’s *** reviewed literature,it was observed that sampled clay within the study area were analyzed using the XRD,XRF and ICP-MS *** findings also revealed that the dominant clay minerals within the study area include montmorillonite,illite,and *** the other hand,it was observed that non-clay minerals such as feldspar,quartz,dickite and many others were found with clay as revealed by several schol*** chemical charactertics of clay consists mainly of Al2O3,K2O,CaO and SiO2,with other major oxides such as P2O5,MgO,Fe2O3,TiO2,MnO and *** trace elements such Be,Ba,Sc,Sr,Zr,V and Y were reported to be present in clays deposit found in selected part of Ogun *** reviewed articles,it was observed that mineralogical and chemical charactertics of clay make it suitable for pharmaceutical,textile,cosmetic and polymer industries,but considered to be fairly suitable for oil and gas industry.

关键词： Clay Montmorillonite Kaolinite Illite Oxide Nigeria

Mothers’ Level of Schooling, Monitoring of Their Pregnancy and Perinatal Prognosis at the Reference Health Centre of Commune V of the District of Bamako

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Obstetrics and Gynecology 2023年第2期13卷 383-394页

作者： Albachar Hamidou Sitapha Dembélé Cheickna Sylla Sissoko Hamady Seydou Z. Dao Alou Samaké Saleck Doumbia Cissao chiaka Sanogo Siaka Amara Sema Keita Reference Health Center of Kayes Kayes Mali Reference Health Centre of Commune V of the District of Bamako Bamako Mali National Centre for Scientific and Technological Research in Bamako Bamako Mali Department of Gynecology and Obstetrics of the Fousseyni Daou Hospital in Kayes Kayes Mali Department of Gynecology and Obstetrics of the Gabriel Touré University Hospital Bamako Mali Reference Health Centre of Commune III of the District of Bamako Bamako Mali Reference Health Centre of Commune II of the District of Bamako Bamako Mali Reference Health Centre of Commune VI of the District of Bamako Bamako Mali Reference Health Center of Fana Koulikoro Mali

Introduction: The level of schooling of mothers is a determining factor in the follow-up of pregnancy and consequently the prognosis of childbirth and the quality of the newborn. Objective: The aim was to assess the impact of the level of education on the follow-up of their pregnancy and perinatal prognosis at the Reference Health Centre of Commune V of the District of Bamako. Materials and Methods: This was a prospective, cross-sectional and analytical study aimed descriptive from August 15 to December 15, 2021. We included in this study all pregnant women who had a gestational age of at least 22 weeks of amenorrhea and who gave birth or were received in the immediate postpartum period at the maternity ward of the Reference Health Center of Commune V. Results: Out-of-school parturients accounted for 60% of cases. Among the parturients in school, 18% had a higher level. In our study, 14.3% of women in labour knew the date of the last menstrual period. In our series, 100% of mothers in higher and secondary school had completed an antenatal consultation (CPN) compared to 90.7% in the out-of-school mothers. CPN1 was performed in the first trimester of pregnancy in 21.1% among out-of-school parturients compared to 83.5% among higher-level parturients. The number of NPCs was greater than or equal to 4 in 47.9% of parturients. Conclusion: Women’s schooling has an impact on their socio-economic conditions on the one hand and on the monitoring and prognosis of pregnancies on the other.

关键词： Level Schooling Mothers Aftercare Pregnancy Prognosis

Proximate analyses,in vitro antioxidant activity and GC-MS analyses of fermented Pentaclethra macrophylla seeds

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Life Research 2024年第3期7卷 2-8页

作者： Ikechukwu Okoro Parker Joshua Innocent Okagu Christian Amah Nnamani Ikenna Nene chiaka-Onyemeze Emeka Anaduaka David Obasi Prince Okoroh Daniel Orieke Victor Ogugua Department of Medical Biochemistry College of Health SciencesDavid Umahi Federal University of Health SciencesUburuNigeria Department of Biochemistry University of NigeriaNsukkaNigeria Department of Biochemistry State University of Medical and Applied SciencesIgbo-EnoNigeria Department of Medical Laboratory Sciences State University of Medical and Applied SciencesIgbo-EnoNigeria

The present study assessed the proximate composition,in vitro antioxidant activity and GC-MS analyses of fermented Pentaclethra macrophylla seeds extract(FPMSE).The in vitro antioxidant activity was assessed using 2,2-diphenyl-1-picrylhydrazl(DPPH)while Gas Chromatography-Mass Spectrophotometry(GC-MS)technique was used to identify the volatile compounds in *** revealed a dose dependent percentage inhibition of the extract on DPPH *** composition of FPMSE constitutes respectively;ash(0.33±0.12%),protein(2.19±0.08%),fats and oil(80.60±0.00%),carbohydrate(16.88±0.00%)while moisture and fibre were not ***,the pulverised sample constitute respectively;ash(1.27±0.58%),protein(10.51±0.60%),moisture(8.27±0.12%),fats and oil(32.33±0.12%),fibre(7.27±0.12%)and carbohydrate(40.35±0.00%).GC-MS analyses revealed fourteen(14)fatty acids including Octadecanoic acid(1.95%),Benzyloxymethylimine(43.89%),2-Allylpent-4-enoic acid benzyl ester(26.25%),Hexadecanoic acid,methyl ester(1.09%),Oleic Acid(0.25%),9,12-Octadecadienoic acid,methyl ester(Omega-6-fatty acid)(1.52%).The bioactive compounds identified in FPMSE could contribute to the pharmacological properties of *** seeds and hence,could be of considerable interest for the development of new drugs.

关键词： Pentaclethra macrophylla in vitro antioxidant GC-MS fatty acids

Corneal Blindness Caused by Accidental Ocular Use of Chlorhexidine (Hexz) Gel in Two Newborn Born in the Health District of Kati in Mali

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Ophthalmology 2023年第1期13卷 83-90页

作者： Kadiatou Ba Moro Sidibe Bakary Danfaga Sadio Cissoko Aichata Tall Oumar Diallo Assiatou Simaga Nouhoum Guirou Abdoulaye Napo Adama Dembele Abdoulaye Nouhoum Coulibaly Aoua Ibrahima Toure Mamadou Adama Togo chiaka Sanogo Seydou Bakayoko Fatoumata Sylla Lamine Traore Sanoussi Bamani Institute of Tropical Ophthalmology of Africa (IOTA) Bamako Mali Regional Hospital of Sikasso Mali/Alliance for the Development of Community Ophthalmology (ADOC) Bamako Mali Kati Reference Health Center Koulikoro Mali Alliance for the Development of Community Ophthalmology (ADOC) Bamako Mali

Introduction: Corneal opacities in children are relatively common. In children, it is urgent because of the risk of irreversible amblyopia. The causes of these blindnesses vary considerably according to the regions of the world. Chlorhexidine digluconate is a broad-spectrum antiseptic directed against gram-positive and gram-negative bacteria. It has been used as an antiseptic for more than 50 years, both in humans and in animals. However, despite these benefits, it can cause serious damage if applied to the eyes. Incidents of eye damage with 7.1% chlorhexidine have been reported to WHO across Africa. Observation: We report and write two cases of bilateral corneal blindness caused by accidental ocular use of chlorhexidine (HEXZ) GEL 7.1% in two newborns in the health district of Kati in MALI. The ophthalmological examination had revealed corneal opacity, conjunctival hyperaemia and limbic ischemia greater than 50% in 1 eye out of 4, corresponding to stage IV of the ROPPER HALL classification;2 eyes out of 4 were at stage III and 1 eye out of 4 was at stage I of the same classification. Conclusion: It is essential to ensure correct use of chlorhexidine digluconate gel 7%. It is an antiseptic which should not be used on the ocular and auditory mucous membranes, at the risk of most often permanent burns.

关键词： Chlorhexidine Opacity Cornea Kati