检索结果-南通市图书馆

Newcastle disease virus suppresses antigen presentation via inhibiting IL-12 expression in dendritic cells

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第3期25卷 254-270页

作者： Fulong NAN Wenlong NAN Xin YAN Hui wang Shasha JIANG Shuyun ZHANG Zhongjie YU Xianjuan ZHANG Fengjun LIU Jun LI Xiaoqiong ZHOU Delei NIU Yiquan LI Wei wang Ning SHI Ningyi JIN Changzhan XIE Xiaoni CUI He ZHANG Bin wang Huijun LU Department of Special Medicine Department of Pathogenic BiologySchool of Basic MedicineQingdao UniversityQingdao 266071China china Animal Health and Epidemiology Center Qingdao 266032China Academician Workstation of Jilin Province Changchun University of Chinese MedicineChangchun 130117China Institute of Virology Wenzhou UniversityWenzhou 325035China College of Veterinary Medicine Jilin UniversityChangchun 130012China Changchun Veterinary Research Institute Chinese Academy of Agricultural SciencesChangchun 130122China Sino-Cell Biomed Co. Ltd.Qingdao 266000China

As a potential vectored vaccine,Newcastle disease virus(NDV)has been subject to various studies for vaccine development,while relatively little research has outlined the immunomodulatory effect of the virus in antigen *** elucidate the key inhibitory factor in regulating the interaction of infected dendritic cells(DCs)and T cells,DCs were pretreated with the NDV vaccine strain LaSota as an inhibitor and stimulated with lipopolysaccharide(LPS)for further detection by enzyme-linked immunosorbent assay(ELISA),flow cytometry,immunoblotting,and quantitative real-time polymerase chain reaction(qRT-PCR).The results revealed that NDV infection resulted in the inhibition of interleukin(IL)-12p40 in DCs through a p38 mitogen-activated protein kinase(MAPK)-dependent manner,thus inhibiting the synthesis of IL-12p70,leading to the reduction in T cell proliferation and the secretion of interferon-(IFN-),tumor necrosis factor-α(TNF-α),and IL-6 induced by ***,downregulated cytokines accelerated the infection and viral transmission from DCs to T ***,several other strains of NDV also exhibited inhibitory *** current study reveals that NDV can modulate the intensity of the innate-adaptive immune cell crosstalk critically toward viral invasion improvement,highlighting a novel mechanism of virus-induced immunosuppression and providing new perspectives on the improvement of NDV-vectored vaccine.

关键词： Newcastle disease virus Dendritic cells Interleukin-12(IL-12) T cells Immunosuppression

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Deactivation mechanism of acetone to isobutene conversion over Y/Beta catalyst

引用

chinese Journal of Catalysis 2024年第9期64卷 133-142页

作者： Chang wang Tingting Yan Weili Dai School of Materials Science and Engineering Nankai UniversityTianjin 300350China College of Science Civil Aviation University of ChinaTianjin 300300China

The conversion of acetone derived from biomass to isobutene has attracted extensive *** comparison with Brønsted acidic catalyst,Lewis acidic catalyst could exhibit a better catalytic performance with a higher isobutene ***,the catalyst stability remains a key problem for the long-running acetone conversion and the reasons for catalyst deactivation are poorly understood up to ***,the deactivation mechanism of Lewis acidic Y/Beta catalyst during the acetone to isobutene conversion was investigated by various characterization techniques,including acetone-temperature-programmed surface reaction,gas chromatography-mass spectrometry,in situ ultraviolet-visible,and 13C cross polarization magic angle spinning nuclear magnetic resonance spectroscopy.A successive aldol condensation and cyclization were observed as the main side-reactions during the acetone conversion at Lewis acidic Y *** comparison with the low reaction temperature,a rapid formation and accumulation of the larger cyclic unsaturated aldehydes/ketones and aromatics could be observed,and which could strongly adsorb on the Lewis acidic sites,and thus cause the catalyst deactivation *** a simple calcination,the coke deposits could be easily removed and the catalytic activity could be well restored.

关键词： Deactivation mechanism Acetone to isobutene Lewis acid sites Y/Beta Spectroscopy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A high torque dual 3-phase permanent magnet vernier machine with strong fault-tolerance

引用

Science china Technological Sciences 2024年第10期67卷 3275-3284页

作者： XU YuWen wang Bo wang RongXin CHENG Ming HUA Wei School of Electrical Engineering Southeast University

The field modulation effect has been proposed and investigated in various electric machine topologies. Among them, permanent magnet vernier machines(PMVMs) have attained intensive research due to the high torque density and simple ***, the performance of PMVMs in terms of fault tolerance is seldom mentioned. This article proposes a novel dual 3-phase fault-tolerant PMVM with segregated concentric windings. Benefiting from the field modulation effect, the PMVM can generate high torque with low PM flux. The low PM flux also implies small fault currents in the short-circuit case. Therefore, the PMVM exhibits inherent good fault-tolerant capability without sacrificing torque performance. Two independent 3-phase modular winding sets are adopted to improve redundancy. To realize the physical and electrical isolation, each winding set is controlled by a standard 3-phase inverter. The healthy performance and fault tolerance of the proposed machine are evaluated by finite element analysis and verified by experimental tests. The results infer its advantages in healthy conditions and various fault scenarios,including open-circuit, short-circuit, and interturn short-circuit conditions.

关键词： fault-tolerant capability segregated windings field modulation permanent magnet vernier machine

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Intelligent spectropolarimetry

引用

Light(Science & Applications) 2024年第8期13卷 1463-1463页

作者： Fakun wang d Qi Jie wang School of Electrical&Electronic Engineering&School of Physical and Mathematical Sciences Nanyang Technological UniversitySingaporeSingapore

High-dimensional polarization and spectral information are crucial in a wide range of applications,from everyday life to national ***,obtaining this complex information typically requires cumbersome systems composed of separate polarimeters and *** address this challenge,a team of researchers from the Changchun Institute of Optics,Fine Mechanics and Physics,chinese Academy of Sciences,University of chinese Academy of Sciences,National University of Singapore,and Australian National University has developed an innovative intelligent spectropolarimetry approach.

关键词： Changchun polar everyday

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asexual Reproduction of Aurelia coerulea Polyps in situ on Settling Plates in Jiaozhou Bay, china

引用

Journal of Ocean University of china 2024年第5期23卷 1371-1380页

作者： MI Tiezhu ZHU Jianbin ZHEN Yu wang Guoshan wang Jianyan Key Laboratory of Marine Environment and Ecology Ministry of Education College of Environmental Science and Engineering Ocean University of China Laboratory for Marine Ecology and Environmental Science Qingdao Marine Science and Technology Center Frontiers Science Center for Deep Ocean Multispheres and Earth System Ocean University of China National Marine Hazard Mitigation Service Ministry of Natural Resources Department of Life Sciences National Natural History Museum of China

Jellyfish blooms are increasingly prevalent coastal phenomena, with Aurelia coerulea being a significant contributor. The complex life history of jellyfish, featuring a sessile polyp stage, is a key factor in bloom formation, yet it is challenging to study in the field. This study aimed to describe the asexual reproduction of A. coerulea polyps in Jiaozhou Bay, china, and to assess their ability to form sedentary colonies and their relationship with environmental factors. Using settling plates, we observed polyps in situ and documented three asexual reproduction modes: budding, strobilation, and podocyst formation. Environmental parameters including temperature, salinity, dissolved oxygen(DO), chlorophyll a(Chl a), and the biomass of phytoplankton and zooplankton were monitored. Budding was the predominant reproductive method, featuring stolon budding in autumn and direct budding during the winter and spring seasons. Strobilation took place in the colder months, releasing ephyrae between April and May. Polyp abundance was positively correlated with seawater temperature and negatively correlated with DO concentration. Polyps at 1.0 m depth showed higher survivorship and proliferation over 8 months, whereas those at 2.0 m depth experienced a steady decline and died within 4 months. The study enhances our understanding of the life cycle and asexual reproduction strategies of A. coerulea polyps in the field, with implications for predicting and managing jellyfish blooms. The findings underscore the importance of temperature and DO in polyp survival and suggest that initial polyp population proliferation is crucial for long-term survival.

关键词： asexual reproduction budding jellyfish bloom polyps strobilation

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Recent advances in COhydrogenation to higher alcohols

引用

Science china Chemistry 2024年

作者： Qian Zhang Sen wang Mei Dong Jianguo wang Weibin Fan State Key Laboratory of Coal Conversion Institute of Coal Chemistry Chinese Academy of Sciences University of chinese Academy of Sciences

CO2hydrogenation to higher alcohols(C2+OH) is an effective way to realize carbon recycling, which can not only reduce the CO2amounts in atmosphere and mitigate the greenhouse effect, but also provides a new route to synthesize important ***, this process is a challenge because the inert CO2molecule is difficult to be activated and undergo C–C coupling. The key to achieve selective conversion of CO2to C2+OH is to design high-performance catalytic systems and unravel the reaction mechanism. In this review, we report several typical CO2hydrogenation-to-C2+OH catalyst materials, including noble-metal catalysts, Cu-based catalysts, Co-based catalysts and Mo-based catalysts, and evaluate the effects of various promoters on the catalytic performance and reaction mechanism. It will provide not only fundamental insights into the CO2hydrogenation-toC2+OH reaction mechanism, but also guidance for the development of related high-performance catalysts.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

融合与共生:藏传佛教建筑中国化的哲思演变与实践路径探究

引用

西藏大学学报（社会科学版） 2024年第2期39卷 148-154页

作者：池梦洁东南大学建筑学院江苏南京210096

文章深入探讨了藏传佛教建筑中国化现象背后的哲学思想根源及其在建筑营造上的体现,分析了“依正不二”与“缘起性空”的哲学思想如何影响藏传佛教建筑的规划选址和建造格局,以及如何与汉文化的“象天法地”和“中正和合”思想相融合,... 详细信息

文章深入探讨了藏传佛教建筑中国化现象背后的哲学思想根源及其在建筑营造上的体现,分析了“依正不二”与“缘起性空”的哲学思想如何影响藏传佛教建筑的规划选址和建造格局,以及如何与汉文化的“象天法地”和“中正和合”思想相融合,形成独特的建筑风格和文化价值观。研究不仅对藏传佛教建筑的中国化过程进行了系统的分析,也深入挖掘了民族文化精神在文化融合与发展中的重要作用,为理解藏传佛教中国化的复杂性和动态性提供了新的视角。

关键词：藏传佛教建筑中国化依正不二缘起性空文化融合

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

十论、墨义、后墨学流派——试论墨家主张的互洽性与表征形式

引用

文史哲 2024年第4期 101-110,167页

作者：刘太刚张驰中国人民大学公共管理学院北京100872

墨学的互洽逻辑不是建立在抽象的理论演绎基础之上,而是以构建平等之爱的治理理念与乱世背景下的治理实践的内在统一为支撑。墨子早年师从儒者,墨学对儒家思想既有批判,也有在认同基础上的重新阐释,儒墨两家在一定时期内存在对立统一与... 详细信息

墨学的互洽逻辑不是建立在抽象的理论演绎基础之上,而是以构建平等之爱的治理理念与乱世背景下的治理实践的内在统一为支撑。墨子早年师从儒者,墨学对儒家思想既有批判,也有在认同基础上的重新阐释,儒墨两家在一定时期内存在对立统一与互洽共生的关系。墨学以义为载体,论述形上之道与形下之器,墨家之义不是仅存在于墨学的某个具体主张中,而是以其整体思想的形上之道为依据。先秦时期儒墨同为“显学”,在对二家之义的比较中追溯先秦义利思想的本源,可以为墨家之义及其义利等同的理念提供一个新的阐述视角,也有助于理解后世各墨学流派所秉持之义的异化。针对原初之义的遮蔽及由此遮蔽所产生的后墨学流派的政治主张进行有限推断,可以见出墨学不同流派在理论实践与治理环境的互洽中的表征形式存在必然性与合理性,而这种现象亦符合墨学“凡入国必择务而从事”的表述。

关键词：墨学义互洽性先秦思想后墨学流派

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Surface ligand-promoted heterogeneous COcatalysis

引用

Science china Chemistry 2024年

作者： Zhe Lu Lu wang School of Science and Engineering The Chinese University of Hong Kong

Heterogeneous CO2catalysis towards the synthesis of high-value products provides a potent pathway for achieving carbon neutrality. The distinctive attributes of surface ligands allow for highly effective tuning of the kinetics and mechanisms to enhance CO2conversion performance. In this review, the catalytic contributions of surface ligands from the view of structure modulation, mechanism modulation, mass transfer, and energy transfer were summarized. The relationships between surface ligands and the performance of functionalized catalysts were further explored. Subsequently, the applications of hydrocarbon chain spacer, hydroxyl and amino as terminal, and SiOxligand in thermal, photo, and photothermal CO2conversion were investigated. By examining the current limitations and advancements, we concluded with insights into potential future research directions that focus on the development of precisely tuned active sites for highly efficient CO2conversion.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

V含量对高氮马氏体不锈钢组织及性能的影响

引用

金属热处理 2024年第3期49卷 215-221页

作者：张浩迟宏宵王成蹊马党参林鹏昆明理工大学材料科学与工程学院云南昆明650093 钢铁研究总院有限公司特殊钢研究院北京100081 昆明理工大学交通工程学院云南昆明650093 河北机电职业技术学院河北邢台054000 山东南山铝业股份有限公司山东龙口265700

采用光学显微镜、SEM、硬度试验、冲击试验、盐雾腐蚀试验对两种不同V含量(0.32%和0.80%)的高氮马氏体不锈钢(根据V含量分别命名为0.3V钢和0.8V钢)的组织和力学性能进行研究。结果表明,两种不同V含量试验钢的退火组织中均出现碳化物条带... 详细信息

采用光学显微镜、SEM、硬度试验、冲击试验、盐雾腐蚀试验对两种不同V含量(0.32%和0.80%)的高氮马氏体不锈钢(根据V含量分别命名为0.3V钢和0.8V钢)的组织和力学性能进行研究。结果表明,两种不同V含量试验钢的退火组织中均出现碳化物条带,0.8V钢中碳化物条带更加明显,其退火硬度为257.0 HBS,相较于0.3V钢提高7%;V含量的提高能降低淬火后奥氏体晶粒的尺寸和残留奥氏体含量;经相同热处理(1050℃淬火30 min+(-73℃)冷处理2 h+250℃回火2 h)后,0.3V钢硬度为58.4 HRC,冲击吸收能量为9.4 J,0.8V钢的硬度为54.4 HRC,冲击吸收能量为12.7 J,V含量的增加,降低了马氏体不锈钢的硬度,提高了其韧性;经120 h的盐雾腐蚀后,0.3V钢表面无明显腐蚀坑,腐蚀速率为0.0235 g·m^(-2)·h^(-1),0.8V钢表面有明显的腐蚀坑,腐蚀速率为0.0258 g·m^(-2)·h^(-1),0.3V钢的耐腐蚀性能略优于0.8V钢,即随着V含量增加,耐蚀性略有下降。

关键词：高氮马氏体不锈钢 V含量组织力学性能耐蚀性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：