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Perceptions and Knowledge about Cervical Cancer among Women Living with HIV in Parakou in 2017

2000上海科技论坛BIO-X研讨会暨中德医学生物物理和上海流变学研讨会

作者： Jf. Zhou,ak.Bosserhof and GM. ArtmannDepartment of Applied Cell Biophysics and Bioengineering,AachenUniversity of Applied Sciences,Juelich 52428,Germany. Institutes of Pathology,Aachen University Hospital,Aachen 52074,Germany.

In this study,Protocatechuic acid(Pac), a water-soluble component of Salvia Miltiorriza Bge, on theability of the vascular endotheliun to respond to tumor necrosis factor is inveshgated. In the presenceof a protein srpthesis inhibitor, actinomycin D, tumor necrosis factor(TNF-a)induces humanumbilical vein endothelial cells(HUVECs)to undergo apoptosis. Pretreating HUVECs with Pac for 2h,enhances survival cells for 1.5 fold, suggesting that Pac inducible cytoprotective pathway occurs forcell survive. Howevef, this cell death prevention effect of Pac is markedly blocked when a nuclearfactor kappa B(NF-kB) activation iuhibitor MG132 is added. It indicates that NF-kB may be

关键词： Protocatechuic acid tumor necrosis factor nuclear factor

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Open Journal of Epidemiology 2022年第1期12卷 31-49页

作者： Luc Béhanzin Luc Valère Codjo Brun Elfried Salanon Marie-Claire Assomption Oloufoudi Balle Pognon Ella Goma-Matsétsé Maurice Agonnoudé David Houéto Thierry Adoukonou Benjamin Hounkpatin Marie Thérèse akélé akpo School of Public Health and Epidemiology University of Parakou Parakou Benin Department of Pathological Anatomy Faculty of Medicine University of Parakou Parakou Benin STI Clinic (DIST) Cotonou Community Health Centre 1 Cotonou Benin Obstetrics and Gynecology Service of the Hospital and University Center of the Mother and Child of Lagune (CHUMEL) of Cotonou Cotonou Benin Laboratory of Pathological Anatomy of Cité Houéyiho Faculty of Health Sciences of Cotonou University of Abomey Calavi Godomey Benin

Background: Cervical cancer (CC) is the fourth most common cancer in women and those living with HIV have a six times higher risk of cervical cancer compared to those without. The objective of this study was to assess knowledge and perceptions about cervical cancer in women living with HIV/AIDS (WLWHIV) in the municipality of Parakou in Benin. Methods: This was an analytical cross-sectional study conducted among WLWHIV monitored on antiretrovira (ARV) therapy (ART) centers in Parakou. Study participants were selected by systematic random sampling technique. Data collection took place from September 5, 2017 to November 6, 2017. Log-binomial regression was used to identify associated factors. Results: A total of 167 women were recruited into the study. The median age was 35 years [Interquartile range: 41.50 - 30.00]. More than half of the women had no perception of the cause of CC. Only 12.6% of women believed in the preventive capacity of early screening of CC. Among women, 15.6% knew that it can be prevented, but only 9.6% had heard of HPV and 4.8% knew that HPV vaccination is an effective means of preventing CC. The factors associated with the low level of knowledge were the age at first sexual intercourse (≤24 years), the ART follow-up site (private health structure) and the fact of not having visited a maternity hospital in the last 12 months preceding the survey. Conclusion: The perceptions and knowledge about cervical cancer in the population of women living with HIV and monitored on ART in Parakou were inadequate and disproportionate to their vulnerability to this cancer. In order to avoid a double burden on these women, their ART centers must integrate cervical cancer prevention interventions into ART initiation services.

关键词： Perceptions Knowledge Cervical Cancer Benin HIV

Assessment of BTEX Concentrations in Air Ambient of Gas Stations Using Passive Sampling and the Health Risks for Workers

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Journal of Environmental Protection 2017年第1期8卷 12-25页

作者： Lícia P. S. Cruz Lidmary P. Alve akácia V. S. Santos Mabel B. Esteves ícaro V. S. Gomes Luís S. S. Nunes Analytical Chemistry Department Federal University of Bahia/Chemistry Institute Salvador Brazil Faculty of Technology and Science Salvador Brazil

Gas stations are important emissions source of benzene (C6H6), toluene (C7H8), ethylbenzene (C8H10), and ortho, meta and para-xylene (C8H10)—better known by the acronym BTEX. The objective of this study was to determine the concentrations of BTEX compounds in the ambient air of ten gas stations in the cities of Salvador and Feira de Santana, Bahia, Brazil and evaluate the health risks to workers. Passive samplers diffusive of the Radiello?, containing activated carbon as adsorbent, were used. The samplers were exposed for 8 h and then the analytes were recovered by chemical desorption with CS2 and determined by GC-FID. The BTEX concentrations found in the ambient air of gas stations ranged from 46.72 - 435.43 μg·m?3 for benzene;25.54 - 342.46 μg·m?3 for toluene, 7.10 - 30.07 μg·m?3 for ethylbenzene, 9.36 - 89.73 μg·m?3 for m, p-xylene and 9.79 - 52.29 μg·m?3 for o-xylene. The concentrations of toluene, ethylbenzene and xylenes found in gas stations were lower than the limits recommended by the US NIOSH and NR-15 of the Ministry of Labour of Brazil;however, it should be considered the risks due to chronic exposure of workers. Benzene concentrations in three gas stations were above the exposure limit recommended by NIOSH (3.20 × 102 μg·m?3). Samplings were also held outdoors at 250 m of two gas stations. The total concentrations of the BTEX compounds were equal to 24.97 and 35.51 μg·m?3, and benzene concentrations were about 3 - 4 times higher than the annual pattern of 5.0 μg·m?3 established by Union European, as tolerance limit for outside areas. These data confirm that the next areas of gas stations are subject to the effects of volatilization of these compounds. Additionally, the values found in the 10 gas stations for the cancer risk ranged from 4.06 × 10?5 - 3.78 × 10?4 (mean of 1.82 × 10?4) for workers exposed to benzene for 30 years (acceptable limit equal 1.00 × 10?6). The cancer risk is very high, because the values found are about 40 - 378 times above the a

关键词： BTEX Gas Stations Passive Sampling Health Risk

大学生色觉辨别能力与深度知觉的相关性分析（英文）

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国际眼科杂志 2016年第8期16卷 1412-1418页

作者： Nimet Unay Gundogan Belkis Salman Koctekin AyseGul Kocak Altintas 土耳其安卡拉巴什肯特大学医学专业生理学系 06815 土耳其安塔利亚健康科学大学教育研究院生理学系 07100 土耳其安卡拉健康科学大学教育研究院眼科 06240

目的：评价色觉正常大学生的色觉辨别能力与深度知觉的关系。方法：选取巴什肯特大学医学专业学生52例,其中男性33例（63.46%）,女性19例（36.54%）,平均年龄21.18±2.52岁。参与学生视力正常（20/20）,且经Ishihara假同色测试法显示无... 详细信息

目的：评价色觉正常大学生的色觉辨别能力与深度知觉的关系。方法：选取巴什肯特大学医学专业学生52例,其中男性33例（63.46%）,女性19例（36.54%）,平均年龄21.18±2.52岁。参与学生视力正常（20/20）,且经Ishihara假同色测试法显示无先天性色觉缺陷。运用Gundogan方法确定主视眼（DE）。通过法-孟二氏100色度试验（FM100HT）检验色觉辨别能力,包括左右眼及双眼（TE）的总误差分（TES）、部分误差分（LES）。误差分分为三组：双眼、DE及非主视眼（NDE）。应用TNO检查双眼视觉与立体感,并根据480-15 arc/s范围的立体感水平分为四组。结果：FM100HT的误差分显示无性别差异的TES,蓝黄LES和红绿LES分别为61.22±30.32（58.50）[mean±SD],35.80±19.32（36.50）和25.42±14.65（24.00）。男性受试者（n=31）分别为67.45±29.95（61.00）,40.25±18.83（39.00）和27.19±14.30（24.00）。女性受试者（n=19）分别为51.05±28.84（47.00）,25.52±18.32（28.00）和22.52±31.13（23.00）。根据FM100HT的误差分,得出女性颜色视觉辨别能力高于男性。通过FM100HT将色觉辨别能力分为较高（6%,TES=0~20）,中等（86%,TES=20~100）和较低（8%,TES〉100）,中等水平最为常见（P〈0.05）。DE和NDE的红绿LES分别为24.12±14.70和32.20±14.21,DE和NDE的蓝黄LES分别为34.68±18.95和36.24±17.56。女性（n=19）DE和NDE的红绿色LES分别为21.89±15.06和31.00±22.42;男性（n=31）则为25.48±14.55和32.93±17.31。女性（n=19）DE和NDE蓝黄色LES分别为29.63±18.62和33.42±17.38,男性（n=31）则为37.77±18.78和37.96±17.73。所有学生的TE,DE及NDE的TES和立体视觉水平均进行比较,差异均无统计学意义（P=1）。研究表明色觉辨别能力和双眼深度知觉无关。结论：FM100HT的TES显示：正常人不同个体立体视觉水平无差异,基于色觉分离的TNO检测的深度直觉与色觉辨别能力不相关。在之前的研究中,DE色觉辨别能力优于NDE。但目前研究表明在深度知觉方面DE并非优于NDE。

关键词：色觉色觉辨色能力深度知觉法-孟二氏100色度试验主视眼Gundogan方法 TNO测试

Conventional MRI at presentation does not predict clinical response to radiation therapy in children with diffuse pontine glioma

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中国神经肿瘤杂志 2009年第3期7卷 209-209页

作者： Liu ak Brandon J Foreman NK Fenton LZ Department of Radiation Oncology University of Colorado Denver A nschutz Cancer Pavilion MS F706 1665 Aurora Court Aurora CO 80045 USA arthur

BACKGROUND: Diffuse pontine glioma is a pediatric brain tumor with a median survival time of 1 year and few long-term survivors. Conventional MRI has not been shown to predict overall survival. With this dismal prognosis, clinical improvement after radiation therapy might be a more relevant issue. OBJECTIVE: To determine whether initial imaging would predict clinical response. MATERIALS AND METHODS: We performed a retrospective review of children with diffuse pontine glioma treated at The Children's Hospital, Denver, and the University of Colorado-Denver from 1995 to 2008. The 30 children were divided into two groups based on acute clinical response to radiation therapy.

关键词：脑胶质瘤儿童临床分析急性放射反应

Quantitative Ultrasound Elastography of Breast: A Review and Update with Emphasis on Shear Wave Imaging (ARFI)

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联合应用血清富组氨酸糖蛋白水平和子宫动脉多普勒超声检查预测先兆子痫

Open Journal of Medical Imaging（医学影像期刊） 2021年第2期

作者： Duzgun Yildirim Özlem akıncı Deniz Esin Tekcan

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中华高血压杂志 2013年第6期21卷 598-598页

作者： Bolin M Wikstrm ak Wiberg-Itzel E Olsson ak Ringvall M Sundstrm-Poromaa I Axelsson O Thilaganathan B kerud H 罗冬梅叶鹏

富组氨酸糖蛋白（histidine-rich glycoprotein，HRG）是一种与血管生成、凝血系统及炎症反应相互作用的蛋白质，上述过程在妊娠先兆子痫时可发生变化。与健康孕妇相比，后期进展为先兆子痫的孕妇早在妊娠头3月HRG水平即明显降低。

关键词：富组氨酸糖蛋白先兆子痫多普勒超声检查子宫动脉蛋白水平预测血清健康孕妇

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针对周围型肺病变的机器人支气管镜检查

中华结核和呼吸杂志 2021年第4期44卷 359-359页

作者： Chen AC Pastis NJ Jr Mahajan ak 肖云肖奎朱芷若不详中南大学湘雅二医院呼吸与危重症医学科 410011

背景:周围型肺病变(PPL)的诊断一直是临床难题。尽管引导性支气管镜检查已广泛应用,但PPL的诊断阳性率并未明显提高。已经研发的机器人辅助支气管镜有望提高PPL的诊断阳性率。目前,评估机器人支气管镜系统在真人受试者中的性能的数据有限。

关键词：机器人支气管镜检查诊断阳性率肺病变 PPL 引导性受试者

Noncontrast-enhanced MRI-based Noninvasive Score for Portal Hypertension(CHESS1802):An International Multicenter Study

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Journal of Clinical and Translational Hepatology 2021年第6期9卷 818-827页

作者： Yanna Liu Tianyu Tang NecatiÖrmeci Yifei Huang Jitao Wang Xiaoguo Li Zhiwei Li Weimin An Dengxiang Liu Chunqing Zhang Changchun Liu Jinqiang Liu Chuan Liu Guangchuan Wang Cristina Mosconi Alberta Cappelli Antonio Bruno Seray akçalar EmrecanÇelebioğlu EvrenÜstüner Sadık Bilgiç Zeynep Ellik ÖzgünÖmer Asiller Lei Li Haijun Zhang Ning Kang Dan Xu Ruiling He Yan Wang Yang Bu Ye Gu Shenghong Ju Rita Golfieri Xiaolong Qi CHESS Center Institute of Portal HypertensionThe First Hospital of Lanzhou UniversityLanzhouGansuChina CHESS Center The Sixth People’s Hospital of ShenyangShenyangLiaoningChina Department of Infectious Disease Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdongChina Department of Microbiology and Infec-tious Disease Center School of Basic Medical SciencesPeking University Health Science CenterBeijingChina Depart-ment of Radiology Zhongda HospitalMedical School of Southeast UniversityNanjingJiangsuChina Istanbul Health and Technology University Zytinburnu/İstanbulTurkey CHESS Working Party Xingtai People’s HospitalXingtaiHebeiChina Department of Hepatobiliary Surgery The Third People’s Hospital of ShenzhenShenzhenGuangdongChina Department of Radiology Fifth Medical Center of PLA General HospitalBeijingChina Department of Gastroenterol-ogy Shandong Provincial Hospital Affiliated to Shandong UniversityJinanShandongChina Department of Radiology IRCCS Azienda Ospedaliero-Universitaria di BolognaUniversity of BolognaItaly Department of Radiology Ankara University School of MedicineAnkaraTurkey Department of Gastroenterology Ankara University School of MedicineAnkaraTurkey Department of Hepatobiliary Surgery People’s Hospital of Ningxia Hui Autonomous RegionYinchuanNingxiaChina

Background and Aims:This study aimed to determine the performance of the non-invasive score using noncontrastenhanced MRI(CHESS-DIS score)for detecting portal hy-pertension in ***:In this international multicenter,diagnostic study(***,NCT03766880),patients with cirrhosis who had hepatic venous pressure gradient(HVPG)measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China(n=4)and Turkey(n=1)between December 2018 and April 2019.A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November *** segmentation of the liver on fat-suppressed T1-weighted MRI maps,CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface ***:A total of 149 patients were included,of which 124 were from four Chinese hospitals(training cohort)and 25 were from two international hospitals(validation cohort).A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36(p<0.0001)and 0.55(p<0.01)for the training and validation cohorts,*** area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension(CSPH)was 0.81 and 0.9 in the training and validation cohorts,*** intra-class correlation coefficients for assessing the inter-and intra-observer agreement were 0.846 and 0.841,***:A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive ***,this score could be used to detect CSPH in patients with cirrhosis.

关键词： Liver cirrhosis Advanced chronic liver disease Hepatic venous pressure gradient Liver surface nodularity Imaging