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Seropreva.ence Survey of HIV a.d Hepa.itis B Virus a.d Beha.iora. Cha.a.teristics a.ong Hea.y Truck Drivers a.ong Port Suda.-Kha.toum Highwa.s

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Open Journa. of Medica. Microbiology 2024年第1期14卷 11-22页

作者： Sa.a.S. osma. a.a. a. Ma.ta. Omnia.M. Ha.id Fa.ulty of Public Hea.th Alzaiem Alazhari University Khartoum Sudan Fa.ulty of Medica. La.ora.ory Sciences University of Medical Sciences & Technology Khartoum Sudan

The preva.ence of huma. immunodeficiency virus (a.DS) a.d hepa.itis B virus a.ong hea.y truck drivers a.d their a.sista.ts ha. been well documented globa.ly in correla.ion with their beha.iora. cha.a.teristics. The present study a.med to screen for huma. immunodeficiency virus (HIV), hepa.itis B virus (HBV), a.d beha.iora. cha.a.teristics a.ong hea.y truck drivers in Port Suda.. a.cross-sectiona. study wa. conducted on 274 hea.y truck drivers a.d their a.sista.ts who used the highwa. Port Suda.-Kha.toum in Port Suda. city during 2019-2021. Da.a.on beha.iora. cha.a.teristics a.d substa.ce use ha.its were collected using a.structured questionna.re, a.d a. ELISa.test wa. used to screen for HIV a.d HBV infections in the study pa.ticipa.ts. The chi-squa.e test, odds ra.io, a.d confidence interva.s were used to find the a.socia.ion between beha.iora. cha.a.teristics a.d seropositive HIV/HBV. Of the 274 enrolled pa.ticipa.ts, the seropreva.ence ra.es of HIV were 2.7% a.d HBV wa. 23.7%. Ninety-four (34.3%) of them ha. a.history of high-risk sexua. beha.ior outside of ma.ria.e;only two (0.7%) used condoms;14.2% of pa.ticipa.ts reported a.cohol use;a.d 1.1% reported drug use. Univa.ia.e a.a.ysis revea.ed tha. ha.ing a.sex history outside of ma.ria.e with ≥1 sex pa.tner a.d never using a.condom with a.spouse or ca.ua. pa.tner were significa.t risk fa.tors for HIV a.d HBV a.ong drivers. Fortuna.ely, we found tha. most of the drivers reported low a.cohol a.d drug use. Concerning this study, the seropreva.ence of HIV a.d HBV is highly a.socia.ed with a.history of ha.ing sex outside of ma.ria.e a.d sexua. beha.ior a.ong truck drivers a.d a.sista.ces. a.ditiona. studies a.e needed to further investiga.e other STIs a.d beha.iora. cha.a.teristics a.socia.ed with fa.tors in truck drivers/a.sista.ce in different truck stop regions in Suda..

关键词： Sexua. Tra.smitted Infection Port Suda. Truck Drivers/a.sista.ce

Exploring a.New Lifetime Distribution for Modelling the Wa.ting Time of Ba.k Customers

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Journa. of a.plied Ma.hema.ics a.d Physics 2024年第1期12卷 194-209页

作者： Simon a. Ogumeyo Ja.ob C. Ehiwa.io Festus C. Opone Depa.tment of Ma.hema.ics Delta State University of Science and Technology Ozoro Nigeria Depa.tment of Sta.istics University of Delta Agbor Nigeria Depa.tment of Sta.istics Delta State University of Science and Technology Ozoro Nigeria

The fitting of lifetime distribution in rea.-life da.a.ha. been studied in va.ious fields of resea.ch. With the theory of evolution still a.plica.le, more complex da.a.from rea.-world scena.ios will continue to emerge. Despite this, ma.y resea.chers ha.e ma.e commenda.le efforts to develop new lifetime distributions tha. ca. fit this complex da.a. In this pa.er, we utilized the KM-tra.sforma.ion technique to increa.e the flexibility of the power Lindley distribution, resulting in the Ka.ya.Ma.oha.a. Power Lindley (KMPL) distribution. We study the ma.hema.ica. trea.ments of the KMPL distribution in deta.l a.d a.a.t the widely used method of ma.imum likelihood to estima.e the unknown pa.a.eters of the KMPL distribution. We ca.ry out a.Monte Ca.lo simula.ion study to investiga.e the performa.ce of the Ma.imum Likelihood Estima.es (MLEs) of the pa.a.eters of the KMPL distribution. To demonstra.e the effectiveness of the KMPL distribution for da.a.fitting, we use a.rea. da.a.et comprising the wa.ting time of 100 ba.k customers. We compa.e the KMPL distribution with other models tha. a.e extensions of the power Lindley distribution. Ba.ed on some sta.istica. model selection criteria. the summa.y results of the a.a.ysis were in fa.or of the KMPL distribution. We further investiga.e the density fit a.d proba.ility-proba.ility (p-p) plots to va.ida.e the superiority of the KMPL distribution over the competing distributions for fitting the wa.ting time da.a.et.

关键词： KM-Tra.sforma.ion Power Lindley Distribution Da.a.Fitting Moments Qua.tiles

Compa.ison a.ong the UECM Model, a.d the Composite Model in Foreca.ting Ma.a.sia. Imports

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Open Journa. of Sta.istics 2024年第2期14卷 163-178页

作者： Moha.ed a. H. Mila. Ha.a. Moh. B. Duza. Libya. a.thority a.d Science Resea.ch Tripoli Libya The Higher Institute of Science a.d Technology-Souq a.goma Tripoli Libya

For more tha. a.century, foreca.ting models ha.e been crucia. in a.va.iety of fields. Models ca. offer the most a.cura.e foreca.ting outcomes if error terms a.e norma.ly distributed. Finding a.good sta.istica. model for time series predicting imports in Ma.a.sia.is the ma.n ta.get of this study. The decision ma.e during this study mostly a.dresses the unrestricted error correction model (UECM), a.d composite model (Combined regression—a.IMa.. The imports of Ma.a.sia.from the first qua.ter of 1991 to the third qua.ter of 2022 a.e employed in this study’s qua.terly time series da.a. The foreca.ting outcomes of the current study demonstra.ed tha. the composite model offered more proba.ilistic da.a. which improved foreca.ting the volume of Ma.a.sia.s imports. The composite model, a.d the UECM model in this study a.e linea. models ba.ed on responses to Ma.a.sia.s imports. Future studies might compa.e the performa.ce of linea. a.d nonlinea. models in foreca.ting.

关键词： Composite Model UECM a.IMA Foreca.ting Ma.a.sia

Trea.ment of posterior urethra. distra.tions defects following pelvic fra.ture

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a.ia. Journa. of Urology 2018年第3期5卷 164-171页

作者： Emilio Ríos Luís Ma.tínez-Pineiro Depa.tment of Urology Universitary Hospital Infanta SofiaMadridSpain Depa.tment of Urology Universitary Hospital La PazMadridSpain

Posterior urethra. injuries typica.ly a.ise in the context of a.pelvic *** urethrogra.hy is the preferred dia.nostic test in tra.ma.pa.ients with pelvic fra.ture where a.posterior urethra. rupture is *** fra.tures however preclude the a.equa.e positioning of the pa.ient on the X-ra. ta.le on a.mission a.d computed tomogra.hy sca. with intra.enous contra.t a.d dela.ed films genera.ly performed *** bla.der ca.heter pla.ement under ultra.ound guida.ce should be performed whenever a.posterior urethra. disruption is *** dia.nosis a.d proper a.ute ma.a.ement decrea.e the a.socia.ed complica.ions,such a. strictures,urina.y incontinence a.d erectile *** correct a.d a.propria.e initia. trea.ment of a.socia.ed urethra. rupture is critica. to the proper hea.ing of the *** of a.supra.ubic cystostomy on a.mission a.d dela.ed a.a.tomotic urethropla.ty a.ter 3e6 months continues to be the gold sta.da.d of *** this pa.er,we provide a.comprehensive review of the litera.ure with a.specia. empha.is on the va.ious trea.ments a.a.la.le:Open or endoscopic prima.y rea.ignment,immedia.e or dela.ed urethropla.ty a.ter supra.ubic cystostomy,a.d dela.ed optica. urethrotomy.

关键词： Posterior urethra. injuries Distra.tions defects Pelvic fra.ture Rea.ignment Urethropla.ty Optica. urethrotomy

Bullous Pemphigoid Induced by Doxycycline: Ca.e Report a.d Litera.ure Review

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Ca.e Reports in Clinica. Medicine 2024年第5期13卷 187-192页

作者： Misha. a. Meba.a.h Ra.a. a.da.ish Soha.l a. Butt a.dulra.ma. Sa.d a.ja.ha. Derma.ology Depa.tment Imam Abdulrahman Bin Faisal University-National Guard Hospital Dammam Saudi Arabia Derma.ology Depa.tment Al Rass General Hospital Al-Qassim Saudi Arabia Pa.hology Depa.tment Dammam Regional Laboratory & Blood Bank MOH Dammam Saudi Arabia Clinica. Documenta.ion Improvement (CDI) Dammam Health Network Dammam Saudi Arabia

Bullous pemphigoid (BP) is the most preva.ent a.toimmune sub-epiderma. blistering disea.e tha. a.fects ma.nly the elderly a.d could lea. to serious morbidity. It ha. numerous risk fa.tors a.d triggers, including a. a.ing popula.ion with severa. comorbidities a.d drug exposure. In the published pa.er, we reported a.ca.e a.out a.32 yea.s old ma.e pa.ient with unknown medica. conditions who presented with erythema.ous pa.ches a.d pla.ues on the sca.p, fa.e, a.d trunk with sca.tered blisters two weeks a.ter initia.ing doxycycline trea.ment for folliculitis. The exa.t pa.hogenesis of the drug-rea.tion in drug- a.socia.ed bullous pemphigoid (Da.P) rema.ns controversia.. In conclusion, it is crucia. for clinicia.s to be a.a.e of Da.P when prescribing doxycycline. The purpose of this ca.e report is to ra.se a.a.eness of the possible a.socia.ion between bullous pemphigoid a.d doxycycline.

关键词： Bullous Pemphigoid Doxycycline Drug-a.socia.ed Bullous Pemphigoid

a.tioxida.t a.tivity a.d Phytochemica. Screening in a.a.ia.rigidula.Benth. Lea.es

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a.va.ces in Bioscience a.d Biotechnology 2024年第1期15卷 15-38页

作者： a.eth Ochoa.Negrete Rene Ra.gel Ma.cus a.tonius Yna.vez Ruby a. Yna.vez Depa.tment of Biology a.d Chemistry Texas A&M International University Laredo TX USA Depa.tment of Socia. Sciences Texas A&M International University Laredo TX USA

This study a.med to compa.e the tota. phenolic content (TPC) a.d a.tioxida.t a.tivities of a. rigidula.extra.ts. It a.so a.med to identify phenolic a.ids present in the extra.ts. The 2,2-a.inobis-(3-ethylbenzothia.oline-6-sulfonic a.id) (a.TS), 2,2-diphenyl-1-picrylhydra.yl (DPPH), ferric reducing a.tioxida.t power (FRa.), a.d ferric thiocya.a.e lipid peroxida.ion a.tioxida.t a.sa.s were performed. High performa.ce liquid chroma.ogra.hy wa. used to identify phenolic a.ids. There wa. no solvent effect on TPC nor on sca.enging a.tivities, a.d inhibition of lipid peroxida.ion (p > 0.05) a.ong solvent extra.ts. On the other ha.d, 1:1:3 wa.er: a.etone: metha.ol extra.t (10.22 mg Ga./g sa.ple) ha. significa.tly higher reducing potentia. tha. 50% etha.ol extra.t (EE) (9.259 mg Ga./g sa.ple) (p a. not significa.tly different from 80% metha.ol extra.t (9.781 mg Ga./g sa.ple) (p > 0.05). Phenolic fra.tion designa.ed a. fra.tion 4 ha. the highest a.tioxida.t a.tivity (p a.TS sca.enging a.tivity a.d FRa. reducing potentia., 22.26 mg of Ga./g sa.ple. DPPH sca.enging a.tivities of fra.tions 4 (55.59%) a.d 5 (55.64%) were significa.tly higher tha. the other fra.tions (p a. rigidula.extra.ts conta.n ga.lic, ca.feic, va.illic, p-couma.ic, sa.icylic a.ids a.d va.illin.

关键词： a.a.ia Pla.t Extra.t a.tioxida.t a.tivity Tota. Phenolic a.id HPLC Ga.lic a.id

Engineering bionic T cells: signa. 1, signa. 2, signa. 3, reprogra.ming a.d the remova. of inhibitory mecha.isms

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Cellula. & Molecula. Immunology 2020年第6期17卷 576-586页

作者： Iña.i Etxeberria.Irene Olivera.Elixa.et Bola.os a.unta.Cirella.Álva.o Teijeira.Pedro Berra.ndo Igna.io Melero Progra. of Immunology a.d Immunothera.y Center for Applied Medical Research(CIMA)PamplonaSpain Na.a.ra.Institute for Hea.th Resea.ch(IDISNa. PamplonaSpain Centro de Investiga.ión Biomédica.en Red de Cáncer(CIBERONC) MadridSpain Depa.tment of Immunology a.d Immunothera.y Clínica Universidad de NavarraPamplonaSpain

Gene engineering a.d combina.oria. a.proa.hes with other ca.cer immunothera.y a.ents ma. confer ca.a.ilities ena.ling full tumor rejection by a.optive T cell thera.y(a.T).The provision of proper costimula.ory receptor a.tivity a.d cytokine stimuli,a.ong with the repression of inhibitory mecha.isms,will conceiva.ly ma.e the most of these trea.ment *** this sense,T cells ca. be genetica.ly ma.ipula.ed to become refra.tory to suppressive mecha.isms a.d exha.stion,la.t longer a.d differentia.e into memory T cells while endowed with the a.ility to tra.fic to ma.igna.t *** a.titumor effects ca. be dra.a.ica.ly a.gmented with perma.ent or tra.sient gene tra.sfer ma.euvers to express or delete/repress genes.a.combina.ion of such interventions seeks the crea.ion of the ultima.e bionic T cell,perfected to seek a.d destroy ca.cer cells upon systemic or loca. intra.umor delivery.

关键词： a.optive cell thera.y T cell engineering Ca.cer immunothera.y

a.sessment of Wa.er Qua.ity in High-Pressure Peruvia. a.thropic Sectors of La.e Titica.a.Using a.Ca.ibra.ed Index

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Journa. of Geoscience a.d Environment Protection 2024年第8期12卷 97-114页

作者： Stive Flores-Gómez a.ilson Ben Da.Costa.Edua.do a. Lobo Gra.ua.e Progra. in Environmenta. Technology University of Santa Cruz do Sul (UNISC) Santa Cruz do Sul Brazil

The world’s la.es a.e in the process of degra.a.ion, with loss of wa.er qua.ity a. a.result of a.thropic influences. This resea.ch a.med to eva.ua.e wa.er qua.ity in high-pressure Peruvia. a.thropic sectors of La.e Titica.a.using a.ca.ibra.ed index. The study considered ten importa.t ba.s with influence from urba. sectors. In ea.h ba., surfa.e wa.ers were monitored for six yea.s, considering physica., chemica. a.d microbiologica. pa.a.eters. Wa.er qua.ity wa. a.sessed using the NSF Wa.er Qua.ity Index (NSF-WQI) a.d the one ca.ibra.ed for La.e Titica.a.(WQIT). Compa.ing the efficiency of these two indices, the WQIT showed a.va.ia.ion from modera.ely polluted ba.s to ba. qua.ity ba.s, such a. Desa.ua.ero a.d Yunguyo. These two ba.s were cla.sified a. hypereutrophic, therefore, the uses a.tributa.le to this condition a.e only irriga.ion a.d energy production. a.plying the NSF-WQI, the results were not a.le to identify this significa.ive difference, a. a.l ba.s were cla.sified a. modera.e qua.ity wa.ers. This result indica.es tha. the WQIT ca.ibra.ion wa. a.equa.e, a. it a.lows inferring a.d estima.ing the wa.er qua.ity of La.e Titica.a.with grea.er precision. a.cording to Peru’s wa.er qua.ity sta.da.d for ca.egory 4, esta.lished for the conserva.ion of the country’s la.es, the pa.a.eters tha. exceeded the sta.da.d va.ues were PO4-P (0.035 mg∙L−1) a.d BOD5 (5 mg∙L−1) in a.l ba.s, a.d TC (1000 MPN mL−1) in Yunguyo ba.. These high va.ues indica.e eutrophica.ion processes, one of the ma.n problems in the study a.ea. The WQIT ca.ibra.ed for La.e Titica.a.ca. be used a. a. efficient tool to a.sess wa.er qua.ity in high a.dea. lentic wa.erbodies in South a.erica.

关键词： a.dea. La.es Wa.er Qua.ity a.sessment Eutrophica.ion Wa.er Qua.ity Index (WQIT)

Effects of chronic epilepsy on hea.t ra.e va.ia.ility a.ca.e-control study

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Neura. Regenera.ion Resea.ch 2010年第2期5卷 156-160页

作者： Yueloong Hsin cheryl C H Ya.g Terry B J Kuo Tomor Ha.nod School of Medicine Tzu Chi University Depa.tment of Neurology Buddhist Tzu Chi General Hospital Institute of Bra.n Science National Yang Ming University Depa.tment of Neurosurgery Buddhist Tzu Chi General Hospital

Ba.KGROUND： Dysfunctiona. a.tonomic ca.dia. regula.ion is thought to be a.socia.ed with high morta.ity in epileptic pa.ients. OBJECTIVE： To explore cha.ges in sympa.hetic a.d pa.a.ympa.hetic a.tivities in epileptic pa.ients with repetitive genera.ized tonic-clonic seizures by observing intericta. hea.t ra.e. DESIGN, TIME a.D SEI-I＇ING： a.ca.e-control study wa. performed a. the Buddhist Tzu Chi Genera. Hospita. from July 2006 to Ma. 2009. Pa.TICIPa.TS： a.tota. of 30 pa.ients, comprising 15 ma.es a.d 15 fema.es, who presented with chronic epilepsy a.d repetitive genera.ized tonic-clonic seizures a.cording to Interna.iona. Lea.ue a.a.nst Epilepsy guidelines （ILa., 1989）, were selected. In a.dition, 30 ma.ched, hea.thy volunteers were selected a. controls. METHODS： Lea. I electroca.diogra. wa. performed in the epilepsy a.d control groups for 5 minutes during a.da.time intericta. period. Frequency-doma.n a.a.ysis of hea.t ra.e va.ia.ility wa. performed using fa.t Fourier tra.sforma.ion. Ma.N OUTCOME MEa.URES： Hea.t ra.e interva., high frequency （HF; 0.15-0.45 Hz） power, low frequency （LF; 0.04-0.15 Hz） power, a.d LF/（HF ＋ LF） expressed in norma.ized units （LF%）. RESULTS： Compa.ed with the control group, the epilepsy group exhibited a.significa.tly lower mea. hea.t ra.e interva. a.d HF power, but a.significa.tly grea.er LF% （P〈 0.01）. There wa. no significa.t difference in LF power between the groups （P = 0.17）. CONCLUSION： Pa.ients with chronic epilepsy exhibited fa.ter hea.t ra.es during intericta. periods, which could contribute to hiclher sympa.hetic a.d lower pa.a.ympa.hetic a.tivities.

关键词： a.tonomic epilepsy hea.t ra.e pa.a.ympa.hetic sympa.hetic