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Real-Time Tunable Gas Sensing Platform Based on SnO_(2) Nanoparticles Activated by Blue Micro-Light-Emitting Diodes

Nano-Micro Letters 2024年第12期16卷 103-119页

作者： Gi Baek Nam Jung-El Ryu Tae Hoon Eom Seung Ju Kim Jun Min Suh Seungmin Lee Sungkyun Choi cheon woo moon Seon Ju Park Soo Min Lee Byungsoo Kim Sung Hyuk Park Jin wook Yang Sangjin Min Sohyeon Park Sung Hwan Cho Hyuk Jin Kim Sang Eon Jun Tae Hyung Lee Yeong Jae Kim Jae Young Kim Young Joon Hong Jong-In Shim Hyung-Gi Byun Yongjo Park Inkyu Park Sang-Wan Ryu Ho Won Jang Department of Materials Science and Engineering Seoul National UniversitySeoul 08826Republic of Korea Research Laboratory of Electronics Department of Mechanical EngineeringMassachusetts Institute of TechnologyCambridgeMA 02139USA Ming Hsieh Department of Electrical and Computer Engineering University of Southern CaliforniaLos AngelesCA 90089USA Department of Display Materials Engineering Soonchunhyang UniversityAsan 31538Republic of Korea Department of Photonics and Nanoelectronics BK21 FOUR ERICA-ACE CenterHanyang University ERICAAnsan 15588Republic of Korea Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea Department of Electronics Information and Communication EngineeringKangwon National UniversitySamcheok 25913Republic of Korea Advance Institute of Convergence Technology Seoul National UniversitySuwon 16229Republic of Korea Department of Mechanical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Department of Physics Chonnam National UniversityGwangju 500-757Republic of Korea

Micro-light-emitting diodes(μLEDs)have gained significant interest as an activation source for gas sensors owing to their advantages,including room temperature operation and low power ***,despite these benefits,challenges still exist such as a limited range of detectable gases and slow *** this study,we present a blueμLED-integrated light-activated gas sensor array based on SnO_(2)nanoparticles(NPs)that exhibit excellent sensitivity,tunable selectivity,and rapid detection with micro-watt level power *** optimal power forμLED is observed at the highest gas response,supported by finite-difference time-domain ***,we first report the visible light-activated selective detection of reducing gases using noble metal-decorated SnO_(2)*** noble metals induce catalytic interaction with reducing gases,clearly distinguishing NH3,H2,and ***-time gas monitoring based on a fully hardwareimplemented light-activated sensing array was demonstrated,opening up new avenues for advancements in light-activated electronic nose technologies.

关键词： Micro-LED Gas sensor array Low power consumption Metal decoration Real-time detection

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Crystal Facet Engineering of TiO_(2) Nanostructures for Enhancing Photoelectrochemical Water Splitting with BiVO_(4) Nanodots

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Nano-Micro Letters 2022年第3期14卷 201-215页

作者： Mi Gyoung Lee Jin wook Yang Hoonkee Park cheon woo moon Dinsefa M.Andoshe Jongseong Park Chang‑Ki moon Tae Hyung Lee Kyoung Soon Choi woo Seok cheon Jang‑Joo Kim Ho Won Jang Department of Materials Science and Engineering Research Institute of Advanced MaterialsSeoul National UniversitySeoul 08826Republic of Korea Department of Chemistry and Nanoscience Ewha Womans UniversitySeoul 03693Republic of Korea National Research Facilities and Equipment Center Korea Basic Science InstituteDaejeon 34133Republic of Korea Advanced Institute of Convergence Technology Seoul National UniversitySuwon 16229Republic of Korea

Although bismuth vanadate(BiVO4)has been promising as photoanode material for photoelectrochemical water splitting,its charge recombination issue by short charge diffusion length has led to various studies about heterostructure *** a hole blocking layer of BiVO4,titanium dioxide(TiO_(2)) has been considered unsuitable because of its relatively positive valence band edge and low electrical ***,a crystal facet engineering of TiO_(2) nanostructures is proposed to control band structures for the hole blocking layer of BiVO4 *** design two types of TiO_(2) nanostructures,which are nanorods(NRs)and nanoflowers(NFs)with different(001)and(110)crystal facets,respectively,and fabricate BiVO4/TiO_(2) heterostructure *** BiVO4/TiO_(2) NFs showed 4.8 times higher photocurrent density than the BiVO4/TiO_(2) *** decay time analysis and time-resolved photoluminescence reveal the enhancement is attributed to the reduced charge recombination,which is originated from the formation of type II band alignment between BiVO4 nanodots and TiO_(2) *** work provides not only new insights into the interplay between crystal facets and band structures but also important steps for the design of highly efficient photoelectrodes.

关键词： Crystal facet control Bismuth vanadate Titanium dioxide Heterojunction Water splitting

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Superhydrophobic and antireflective nanograss-coated glass for high performance solar cells

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Nano Research 2014年第5期7卷 670-678页

作者： Hyo Jin Gwon Yensil Park cheon woo moon Sahn Nahm Seok-Jin Yoon Soo Young Kim Ho Won Jang Electronic Materials Research Center Korea Institute of Science and Technology Seou1136-791 Korea Department of Materials Science and Engineering Korea University Seoul 136-701 Korea School of Chemical Engineering and Materials Science Chung-Ang University Seou1156-756 Korea Department of Materials Science and Engineering Research Institute of Advanced Materials Seoul National University Seou1151-744Korea

We present a facile method for producing superhydrophobic nanograss-coated （SNGC） glass surfaces that possess both reduced reflectivity and self-cleaning properties at the air/glass interface. The refractive index of a CaF2 nanograss （NG） layer on a glass substrate, deposited by glancing angle vapor deposition, is 1.04 at 500 nm, which is the second-lowest value ever reported so far. The fluorinated NG layer gives rise to a high water contact angle （〉150°） and very efficient cleaning out of dust with water drops. Using the dual functionalities of the SNGC glass, we demonstrate superhydrophobic and antireflective organic photovoltaic cells with excellent power conversion efficiency.

关键词： superhydrophobic antireflective self-cleaning nanograss solar cells glancing angle deposition

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Development and application of a multi-step porcine in vitro system to evaluate feedstuffs and feed additives for their efficacy in nutrient digestion, digesta characteristics, and intestinal immune responses

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Animal Nutrition 2024年第2期17卷 265-282页

作者： Hee Yeon Kim Jun-Ok moon Sung woo Kim Application Center CJ Blossom Park Department of Animal Science North Carolina State University

In vitro model provides alternatives to the use of live animals in research. In pig nutrition, there has been a tremendous increase in in vivo research over the decades. Proper utilization of in vitro models could provide a screening tool to reduce the needs of in vivo studies, research duration, cost, and the use of animals and feeds. This study aimed to develop a multi-step porcine in vitro system to simulate nutrient digestion and intestinal epithelial immune responses affected by feedstuffs and feed additives. Seven feedstuffs(corn, corn distillers dried grains with solubles [corn DDGS], barley, wheat, soybean meal, soy protein concentrates, and Corynebacterium glutamicum cell mass [CGCM]), feed enzymes(xylanase and phytase), and supplemental amino acids(arginine, methionine, and tryptophan), were used in this in vitro evaluation for their efficacy on digestibility, digesta characteristics, and intestinal health compared with the results from previously published in vivo studies. All in vitro evaluations were triplicated. Data were analyzed using Mixed procedure of SAS9.4. Evaluations included(1) nutrient digestibility of feedstuffs,(2) the effects of feed enzymes, xylanase and phytase, on digestibility of feedstuffs and specific substrates, and(3) the effects of amino acids, arginine, tryptophan, and methionine, on anti-inflammatory, anti-oxidative, and anti-heat stress statuses showing their effects(P < 0.05) on the measured items. Differences in dry matter and crude protein digestibility among the feedstuffs as well as effects of xylanase and phytase were detected(P < 0.05), including xylo-oligosaccharide profiles and phosphorus release from phytate. Supplementation of arginine, tryptophan, and methionine modulated(P < 0.05) cellular inflammatory and oxidative stress responses. The use of this in vitro model allowed the use of 3 experimental replications providing sufficient statistical power at P < 0.05. This indicates in vitro models can have increased prec

关键词： Digestion Feed additive Feedstuff In vitro Intestine Pig

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Diagnostic and management challenges in primary cutaneous anaplastic large cell lymphoma with necrosis,inflammation,and surgical intervention:A case report

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World Journal of Clinical Cases 2024年第31期12卷 6486-6492页

作者： Jun Mo Kim woo Young Choi Ji Seon cheon Department of Plastic Reconstructive Surgery Chosun University College of MedicineGwangju 61453South Korea

BACKGROUND Primary cutaneous anaplastic large cell lymphoma(PC-ALCL)poses significant diagnostic difficulties due to its similarity in the appearance of skin lesions with chronic inflammatory disorders and other dermatological *** study aims to investigate these challenges by conducting a comprehensive analysis of a case presenting with PC-ALCL,emphasizing the necessity of accurate differentiation for appropriate *** SUMMARY An 89-year-old female patient with diabetes and hypertension presented with arm and abdominal ulcerated mass *** procedures included skin biopsies,histopathological assessments,and immunohistochemistry,complemented by advanced imaging techniques to confirm the *** patient’s lesions were determined as PC-ALCL,characterized by necrosis,chronic inflammation,and a distinct immunophenotypic profile,including CD30,CD3,CD4,and EBER,CD56,MUM-1,Ki 67-positive in>80%of tumor cells,CD10,but negative for anaplastic lymphoma kinase,CD5,CD20,PAX-5,Bcl-2,Bcl-6,CD8,and *** was not reported at the 6-month *** Accurate PC-ALCL differentiation from similar conditions is crucial for effective management and requires a multidisciplinary approach.

关键词： Primary cutaneous anaplastic large cell lymphoma Chronic inflammation Necrosis Diagnostic challenges Dermatological oncology Case report

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Ear keloid and epidermal cyst following auricular cartilage harvest for rhinoplasty:A case report

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World Journal of Clinical Cases 2024年第20期12卷 4434-4439页

作者： Jun Mo Kim Ji Seon cheon woo Young Choi Department of Plastic Reconstructive Surgery Chosun University College of MedicineGwangju 61453South Korea Department of Plastic and Reconstructive Surgery Chosun University College of MedicineGwangju 61453South Korea

BACKGROUND This case report highlights a rare instance of concurrent keloid and epidermal cyst development at an ear cartilage harvest site following rhinoplasty in a 25-year-old *** conditions,which typically stem from skin trauma,seldom occur together,demonstrating the exceptional characteristics of this *** SUMMARY The patient underwent successful surgical removal of both the keloid and the epidermal *** treatment included the use of silicone sheets,gel,and oral tranilast to reduce *** recurrence was observed over a 6-mo follow-up period,indicating effective management of the *** The effective management of complex skin trauma cases underscores the need for individualized treatment strategies in plastic surgery.

关键词： Ear keloids Epidermal cysts Auricular cartilage harvesting Rhinoplasty complications Case report

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SARS-CoV-2 aberrantly elevates mitochondrial bioenergetics to induce robust virus propagation

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Signal Transduction and Targeted Therapy 2024年第6期9卷 2702-2715页

作者： Hye Jin Shin wooseong Lee Keun Bon Ku Gun Young Yoon Hyun-woo moon Chonsaeng Kim Mi-Hwa Kim Yoon-Sun Yi Sangmi Jun Bum-Tae Kim Jong-Won Oh Aleem Siddiqui Seong-Jun Kim Department of Convergent Research of Emerging Virus Infection Korea Research Institute of Chemical TechnologyDaejeon 34114Republic of Korea Gyeongnam Biohealth Research Center Gyeongnam Branch InstituteKorea Institute of ToxicologyJinju 52834Republic of Korea Center for Research Equipment Korea Basic Science InstituteCheongjuChungcheongbuk-do 28119Republic of Korea Department of Biotechnology Yonsei UniversitySeoul 03722Republic of Korea Division of Infectious Diseases School of MedicineUniversity of CaliforniaSan DiegoLa JollaCA 92093USA Present address:Department of Microbiology Chungnam National University School of MedicineDaejeon 35015Republic of Korea

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is a‘highly transmissible respiratory pathogen,leading to severe multiorgan ***,knowledge regarding SARS-CoV-2-induced cellular alterations is *** this study,we report that SARSCoV-2 aberrantly elevates mitochondrial bioenergetics and activates the EGFR-mediated cell survival signal cascade during the early stage of viral ***-CoV-2 causes an increase in mitochondrial transmembrane potential via the SARS-CoV-2 RNAnucleocapsid cluster,thereby abnormally promoting mitochondrial elongation and the OXPHOS process,followed by enhancing ATP ***,SARS-CoV-2 activates the EGFR signal cascade and subsequently induces mitochondrial EGFR trafficking,contributing to abnormal OXPHOS process and viral *** EGFR inhibitors remarkably reduce SARS-CoV-2 propagation,among which vandetanib exhibits the highest antiviral *** of SARS-CoV-2-infected cells with vandetanib decreases SARS-CoV-2-induced EGFR trafficking to the mitochondria and restores SARS-CoV-2-induced aberrant elevation in OXPHOS process and ATP generation,thereby resulting in the reduction of SARS-CoV-2 ***,oral administration of vandetanib to SARS-CoV-2-infected hACE2 transgenic mice reduces SARS-CoV-2 propagation in lung tissue and mitigates SARS-CoV-2-induced lung *** also exhibits potent antiviral activity against various SARS-CoV-2 variants of concern,including alpha,beta,delta and omicron,in in vitro cell culture *** together,our findings provide novel insight into SARS-CoV-2-induced alterations in mitochondrial dynamics and EGFR trafficking during the early stage of viral infection and their roles in robust SARS-CoV-2 propagation,suggesting that EGFR is an attractive host target for combating COVID-19.

关键词： alterations aberrant thereby

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Gender-and Age-Group Specific Association of Persistent Organic Pollutants(POPs)Exposure with Diabetes Mellitus:Korean National Environmental Health Survey(KoNEHS)2015−2017

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Environment & Health 2024年第5期2卷 322-331页

作者： Inae Lee Min Joo Kim Sohyeon Choi Young Joo Park Jeongim Park Gökçe Nur Ayaz Gowoon Lee Yoon Hee Cho Hye Li Jeon Chulwoo Lee Gi Jeong cheon Min Kyong moon Kyungho Choi Graduate School of Public Health Seoul National UniversitySeoul 08826Republic of Korea Institute of Health and Environment Seoul National UniversitySeoul 08826Republic of Korea Department of Internal Medicine Seoul National University College of MedicineSeoul 03080Republic of Korea Seoul National University Hospital Healthcare System Gangnam Center Seoul 06236Republic of Korea Department of Environmental Health Sciences Soonchunhyang UniversityAsan 31538Republic of Korea Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and TechnologySeoul National UniversitySeoul 08826Republic of Korea Center for Environmental Health Sciences Department of Biomedical and Pharmaceutical SciencesUniversity of MontanaMissoulaMontana 59812United States Environmental Health Research Division National Institute of Environmental ResearchMinistry of EnvironmentIncheon 22689Republic of Korea Department of Nuclear Medicine Seoul National University College of MedicineSeoul 03080Republic of Korea Division of Endocrinology Department of Internal MedicineSeoul National University Boramae Medical CenterSeoul 07061Republic of Korea

Exposure to persistent organic pollutants(POPs)has been reported as a potential risk factor for diabetes in ***,effect modifications by sex and age,especially among Asian populations,have seldom been *** the present study,we assessed associations of major POPs exposure including organochlorine pesticides(OCPs),polychlorinated biphenyls(PCBs),and polybrominated diphenyl ethers(PBDEs),with diabetes in Korean adults(n=1,295),a subset of the Korean National Environmental Health Survey(KoNEHS)Cycle 3(2015−2017).In the adult population,serum levels of dichlorodiphenyltrichloroethanes(DDTs)and PCB167 showed an increased odds ratio(OR)for *** stratified by gender,associations became stronger and more consistent in women:In women,serum levels of OCPs including p,p′-DDT,p,p′-dichlorodiphenyldichloroethylene(p,p′-DDE),andΣOCPs and mono-ortho PCBs,such as PCB118 and PCB157,were significantly associated with *** the male participants,however,no significant positive associations were *** stratified by a cutoff age of 50 years,most studied POPs except PBDEs,i.e.,p,p′-DDT,p,p′-DDE,PCB118,PCB157,PCB167,PCB138,and PCB153,showed significant associations with diabetes,in the older *** the younger group,however,no measured POPs showed a significant positive *** of endogenous sex hormones or interaction of POPs on aryl hydrocarbon receptors may partly explain the observed differences by gender and age,although further experimental confirmations should *** findings show that POPs exposure at the current levels is associated with diabetes among general Korean adults,and such associations could be modified by gender and age.

关键词： persistent organic pollutants diabetes age gender toxicity equivalency factor

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Both metaxin and Tom20 together with two mitochondria-specific motifs support mitochondrial targeting of dual-targeting AtSufE1

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Journal of Integrative Plant Biology 2022年第8期64卷 1596-1613页

作者： Seungjin woo Byeongho moon Inhwan Hwang Department of Life Sciences Pohang University of Science and TechnologyPohang 790‐784Korea

Plant cells have two endosymbiotic organelles,chloroplasts,and *** organelles perform specific functions that depend on organelle-specific *** majority of chloroplast and mitochondrial proteins are specifically imported by the transit peptide and presequence,***,a significant number of proteins are also dually targeted to these two ***,it is not fully understood how proteins are dually targeted to both chloroplasts and *** this study,the mechanism underlying mitochondrial targeting of dual targeting At Suf E1 in Arabidopsis was *** N-terminal fragment containing 80 residues of AtSufE1(AtSufE1N80)was sufficient to confer dual targeting of reporter protein,At SufE1N80:GFP,in *** sequence motifs,two arginine residues at 15and 21positions,and amino acid(aa)sequence motif AKTLLLRPLK from the 31to 40aa position,were responsible for targeting to mitochondria a portion of reporter proteins amid the chloroplast *** sequence motif PSEVPFRRT from the 41 stto 50 thaa position constitutes a common motif for targeting to both chloroplasts and *** mitochondrial import of At Suf E1:N80,Metaxin played a critical *** addition,Bi FC and protein pull-down experiments showed that At Suf E1N80 specifically interacts with import receptors,Metaxin and *** interaction of At Suf E1N80 with Metaxin was required for the interaction with *** on these results,we propose that mitochondrial targeting of dual-targeting At Suf E1 is mediated by both mitochondria-specific and common sequence motifs in the signal sequence through the interaction with import receptors,Metaxin and Tom20,in a successive manner.

关键词： AtSufE1 chloroplasts common motif dual targeting metaxin mitochondria mitochondria-specific motif Tom20

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Replica higher-order topology of Hofstadter butterflies in twisted bilayer graphene

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npj Computational Materials 2023年第1期9卷 783-791页

作者： Sun-woo Kim Sunam Jeon moon Jip Park Youngkuk Kim Department of Physics KAISTDaejeonRepublic of Korea Department of Materials Science and Metallurgy University of CambridgeCambridgeUK Department of Energy Science Sungkyunkwan UniversitySuwonRepublic of Korea Center for Theoretical Physics of Complex Systems Institute for Basic Science(IBS)DaejeonRepublic of Korea Department of Physics Hanyang UniversitySeoulRepublic of Korea Department of Physics Sungkyunkwan UniversitySuwonRepublic of Korea

The Hofstadter energy spectrum of twisted bilayer graphene(TBG)is found to have recursive higher-order topological *** demonstrate that higher-order topological insulator(HOTI)phases,characterized by localized corner states,occur as replicas of the original HOTIs to fulfill the self-similarity of the Hofstadter *** show the existence of exact flux translational symmetry in TBG at all commensurate *** on this result,we identify that the original HOTI phase at zero flux is re-entrant at a half-flux periodicity,where the effective twofold rotation is *** addition,numerous replicas of the original HOTIs are found for fluxes without protecting *** the original HOTIs,replica HOTIs feature both localized corner states and edge-localized real-space topological *** replica HOTIs originate from the different interaction scales,namely,intralayer and interlayer couplings,in *** topological aspect of Hofstadter butterflies revealed in our results highlights symmetry-protected topology in quantum fractals.

关键词： properties spectrum topological

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