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Stem cell homing-based tissue engineering using bioactive materials

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Frontiers of Materials Science 2017年第2期11卷 93-105页

作者： Yinxian YU Binbin sun chengqing YI Xiumei MO Department of Orthopaedic Surgery Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200080 China State Key Lab for Modification of Chemical Fibers & Polymer Materials College of Chemistry Chemical Engineering and Biotechnology Donghua University Shanghai 201620 China

Tissue engineering focuses on repairing tissue and restoring tissue functions by employing three elements： scaffolds, cells and biochemical signals. In tissue engineering, bioactive material scaffolds have been used to cure tissue and organ defects with stem cell-based therapies being one of the best documented approaches. In the review, different biomaterials which are used in several methods to fabricate tissue engineering scaffolds were explained and show good properties （biocompatibility, biodegradability, and mechanical properties etc.） for cell migration and infiltration. Stem cell homing is a recruitment process for inducing the migration of the systemically transplanted cells, or host cells, to defect sites. The mechanisms and modes of stem cell homing-based tissue engineering can be divided into two types depending on the source of the stem cells： endogenous and exogenous. Exogenous stem cell-based bioactive scaffolds have the challenge of long-term culturing in vitro and for endogenous stem cells the biochemical signal homing recruitment mechanism is not clear yet. Although the stem cell homing-based bioactive scaffolds are attractive candidates for tissue defect therapies, based on in vitro studies and animal tests, there is still a long way before clinical application.

关键词： stem cell homing cell migration cell proliferation tissue engineering scaffold biochemical signals

Risk assessment and zoning of sea level rise in Shandong Province

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Journal of Oceanology and Limnology 2019年第6期37卷 2014-2024页

作者： LIU Qingrong LI Jian RUAN chengqing YIN Zhonghui JIAO Yan sun Qing LIAN Xihu ZHONG Shan North China Sea Marine Forecasting Center Ministry of Natural Resources(MNR)

Sea level rise is a slow-onset disaster.We collected information about the natural and ecological environments,tides and sea levels,and socio-economic aspects to investigate the distribution and zoning of the risks from sea level rise across Shandong Province.The trends in sea level in different counties of Shandong Province were predicted using moving averages and a random dynamic analysis forecasting model,and the model outputs and socio-economic indicators were combined to assess the risks.The results show that the risks of sea level rise along the western coast of Bohai Bay and Laizhou Bay in Shandong Province were sufficiently large to warrant attention.

关键词： sea level rise risk assessment risk zoning

Insight into tribological problems of green ship and corresponding research progresses

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Friction 2018年第4期6卷 472-483页

作者： Yuwei sun Xinping YAN chengqing YUAN Xiuqin BAI School of Energy and Power Engineering Wuhan University of Technology Reliability Engineering Institute National Engineering Research Center for Water Transport Safety(WTS Center) MoSTWuhan University of Technology Key Laboratory of Marine Power Engineering and Technology MoTWuhan University of Technology Reliability Engineering Institute National Engineering Research Center for Water Transport Safety (WTS Center)MoSTWuhan University of Technology

The so-called "green ship" is being regarded as a potential solution to the problems that the shipping industry faces, such as energy conservation and environmental protection. Some new features, such as integrated renewable energy application, biomimetic materials, and antifriction and wear resistant coating have been accepted as the typical characteristics of a green ship, but the tribology problems involved in these domains have not been precisely redefined yet. Further, the related research work is generally focused on the technology or material itself, but not on the integration of the applicable object or green ship, marine environment, and tribological systematical analysis from the viewpoint of the energy efficiency design index(EEDI) and ship energy efficiency management plan(SEEMP) improvements. Aiming at the tribology problems of the green ship, this paper reviews the research status of this issue from three specific domains, which are the tribology problems of the renewable energy system, tribological research for hull resistance reduction, and energy efficiency enhancement. Some typical tribological problems in the sail-auxiliary system are discussed, along with the solar photovoltaic system and hull drag reduction in traditional marine mechanical equipment. Correspondingly, four domains that should be further considered for the future development target of the green ship are prospected.

关键词：航运业摩擦学仿生材料船舶工程

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碳纤维加固钢筋混凝土板的爆炸试验研究

混凝土 2007年第11期 65-68,72页

作者：孙文彬 chengqing Wu 淮阴工学院土木工程系江苏淮安223001 School of Civil and Environmental Engineering University of Adelaide North Terrance SA 5005 Australia

粘贴或包裹碳纤维布加固钢筋混凝土结构不仅得到了广泛研究,而且已被成熟应用于工程实践。在混凝土保护层嵌入碳纤维(或玻璃纤维)条加固钢筋混凝土结构,具有不改变构件的截面尺寸和外观,不影响建筑效果等优点,正在成为一种新的加固技术... 详细信息

粘贴或包裹碳纤维布加固钢筋混凝土结构不仅得到了广泛研究,而且已被成熟应用于工程实践。在混凝土保护层嵌入碳纤维(或玻璃纤维)条加固钢筋混凝土结构,具有不改变构件的截面尺寸和外观,不影响建筑效果等优点,正在成为一种新的加固技术,尤其适用于公共建筑、经典建筑的加固。选择结构中常用的钢筋混凝土简支单向板为试验对象,在板的保护层分别嵌入6条厚度1.4mm宽度20mm的碳纤维布,研究试件的爆炸响应以及爆炸中所表现的破坏特征,尤其是嵌入的碳纤维的破坏,研究碳纤维在钢筋混凝土板爆炸动力响应中的作用。试验结果证明,保护层嵌入碳纤维(CFRP)可以有效地用于加固遭受爆炸荷载的钢筋混凝土构件和结构。

关键词：碳纤维加固钢筋混凝土板爆炸

20世纪初奥地利维也纳工场珠宝造物中的审美观

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艺术设计研究 2022年第3期 51-57页

作者：赵成清孙行健四川大学艺术学院

20世纪初,一批前卫的艺术家、设计师、手工艺人于奥地利共创了设计工坊“维也纳工场”,并在珠宝、建筑和时装等领域进行了先锋探索,对后世影响至深。在珠宝造物方面,维也纳工场的设计尤为突出,其“整体艺术”和“为艺术而艺术”的造物... 详细信息

20世纪初,一批前卫的艺术家、设计师、手工艺人于奥地利共创了设计工坊“维也纳工场”,并在珠宝、建筑和时装等领域进行了先锋探索,对后世影响至深。在珠宝造物方面,维也纳工场的设计尤为突出,其“整体艺术”和“为艺术而艺术”的造物理念是现代艺术的先声。该工坊成员在材料选用、设计语汇、协作机制等方面呈现出鲜明的创新之处。同时,他们通过刊发多功能的工作手册、制作品种多样的艺术明信片、参与展览和开设分店等形式塑造其文化品牌,为后世首饰设计提供范式,也为当代首饰设计界提供了有益借鉴。

关键词：维也纳工场珠宝设计造物理念设计创新文化品牌

A Comparison of Co-temporal Vector Magnetograms Obtained with HMI/SDO and SP/Hinode

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Research in Astronomy and Astrophysics 2023年第12期23卷 175-183页

作者： Mei Zhang Haocheng Zhang chengqing Jiang National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Astronomy and Space Sciences University of Chinese Academy of SciencesBeijing 100049China High Altitude Observatory National Center for Atmospheric Research3080 Center Green DriveBoulderCO 80301USA Jericho High School 99 Cedar Swamp RoadJerichoNY 11753USA School of Space and Environment Beihang UniversityBeijing 100091China

Accurate measurement of magnetic fields is very important for understanding the formation and evolution of solar magnetic fields.Currently,there are two types of solar magnetic field measurement instruments:filter-based magnetographs and Stokes polarimeters.The former gives high temporal resolution magnetograms and the latter provides more accurate measurements of magnetic fields.Calibrating the magnetograms obtained by filter-based magnetographs with those obtained by Stokes polarimeters is a good way to combine the advantages of the two types.Our previous studies have shown that,compared to the magnetograms obtained by the Spectro-Polarimeter(SP)on board Hinode,those magnetograms obtained by both the filter-based Solar Magnetic Field Telescope(SMFT)of the Huairou Solar Observing Station and by the filter-based Michelson Doppler Imager(MDI)aboard SOHO have underestimated the flux densities in their magnetograms and systematic center-to-limb variations present in the magnetograms of both instruments.Here,using a sample of 75 vector magnetograms of stable alpha sunspots,we compare the vector magnetograms obtained by the Helioseismic and Magnetic Imager(HMI)aboard Solar Dynamics Observatory(SDO)with co-temporal vector magnetograms acquired by SP/Hinode.Our analysis shows that both the longitudinal and transverse flux densities in the HMI/SDO magnetograms are very close to those in the SP/Hinode magnetograms and the systematic center-to-limb variations in the HMI/SDO magnetograms are very minor.Our study suggests that using a filter-based magnetograph to construct a low spectral resolution Stokes profile,as done by HMI/SDO,can largely remove the disadvantages of the filter-type measurements and yet still possess the advantage of high temporal resolution.

关键词： The sun-sun magnetic fields-sun photosphere-(sun:)sunspots

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采用双支路与特征融合网络的路沿分割

计算机工程与应用 2023年第9期59卷 255-261页

作者：孙扬韩磊王程庆李韵鹏河北工程大学机械与装备工程学院河北邯郸056000 邯郸市智能车辆重点实验室河北邯郸056000

路沿检测是智能车辆环境感知的重要目标,使用语义分割的方法对路沿目标进行检测。针对语义分割网络不能平衡浅层特征和深度特征的问题,设计了一种具有双支路特征融合的实时路沿分割网络。网络主支使用残差结构模块进行下采样,在特征图... 详细信息

路沿检测是智能车辆环境感知的重要目标,使用语义分割的方法对路沿目标进行检测。针对语义分割网络不能平衡浅层特征和深度特征的问题,设计了一种具有双支路特征融合的实时路沿分割网络。网络主支使用残差结构模块进行下采样,在特征图分辨率为输入分辨率的1/16时恢复至原来分辨率。采用多个模块来融合浅层空间特征与高级语义特征:使用SDFE(spatial detail feature extraction)模块弥补几何特征的丢失;使用联合特征金字塔(joint feature pyramid,JFP)模块将网络多个阶段具有强语义信息的多尺度特征结合使用;支路中设计了特征注意力机制(feature attention,FA)模块,使用4个卷积归一化,通过注意力模块处理,用来增强空间细节特征的提取;设计了FFM(feature fusion module)模块融合高级语义特征与浅层特征。对网络进行性能评价,该网络测试mIoU为79.65%,FPS为59.6,在道路上进行实车实验,分割快速且效果良好。

关键词：路沿分割双支路特征融合

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基于激光雷达和特征地图的车辆智能定位研究

激光杂志 2023年第12期44卷 190-195页

作者：孙扬王程庆韩磊李毅河北工程大学机械与装备工程学院河北邯郸056000 邯郸市智能车辆重点实验室河北邯郸056000

针对激光雷达采集行驶车辆的三维点云数据中包含过多畸变数据,影响车辆定位效果的问题,本文研究一种基于激光雷达和特征地图的车辆智能定位方法。激光雷达利用基于飞行时间的激光测距法,采集车辆及其行驶环境的三维激光点云数据,去除激... 详细信息

针对激光雷达采集行驶车辆的三维点云数据中包含过多畸变数据,影响车辆定位效果的问题,本文研究一种基于激光雷达和特征地图的车辆智能定位方法。激光雷达利用基于飞行时间的激光测距法,采集车辆及其行驶环境的三维激光点云数据,去除激光点云数据中的畸变数据。利用正态分布变换方法,优化删除畸变数据的点云集的正态分布概率值,配准三维激光点云数据。从完成配准后的三维激光点云数据中,提取柱状物体的圆形特征,构建车辆行驶的自然柱状特征地图。利用卡尔曼滤波算法,结合自然柱状特征地图信息,实现高精度的车辆智能定位。实验结果证明:该方法可以精准定位车辆目标,车辆智能定位精度较高,最高可达到97%,定位效率较好,最短可在5 s时间内完成定位,具有一定应用价值。

关键词：激光雷达特征地图车辆智能定位激光测距正态分布变换卡尔曼滤波

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论宋人对苏轼制诰公文的文本“仿造”

档案学研究 2019年第1期 126-131页

作者：李成晴清华大学人文学院北京100084

苏轼的制诰文同其他苏文一样,皆"相时立说",浸润着其思想与见解的精华,被韩誉为"制诰之杰"。苏轼在借鉴前人的基础上,创造出了"雄深秀伟"的制文风格,对两宋掌制诰者影响深远。起自北宋苏轼之弟苏辙及亲炙后学孙觌、翟汝文,历李纲、周必... 详细信息

苏轼的制诰文同其他苏文一样,皆"相时立说",浸润着其思想与见解的精华,被韩誉为"制诰之杰"。苏轼在借鉴前人的基础上,创造出了"雄深秀伟"的制文风格,对两宋掌制诰者影响深远。起自北宋苏轼之弟苏辙及亲炙后学孙觌、翟汝文,历李纲、周必大、林之奇、刘克庄、真德秀等数十位掌制诰的文士,皆能看出对苏轼制文的模拟。诸人有意识地在制文全篇、文章结构、句段、词汇、用典等方面加以借鉴"仿造",或因袭原文,或模拟化用,共同汇成了苏文在两宋接受史上一支未曾受到关注的潜流。

关键词：苏轼《苏轼文集》内制外制模拟