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Food Science and Human Wellness 2024年第3期13卷 1475-1484页

作者： Fangfang Yan Qun Lu chengming wang Rui Liu College of Food Science and Technology Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Environment Correlative Dietology(Huazhong Agricultural University) Ministry of EducationWuhan 430070China Key Laboratory of Urban Agriculture in Central China Ministry of Agriculture and Rural AffairsWuhan 430070China

Our previous study has revealed that procyanidin A_(1)(A_(1))and its simulated digestive product(D-A,)can alleviate acrylamide(ACR)-induced intestine cell ***,the underlying mechanism remains *** this study,we elucidated the molecular mechanism for and D-A_(1) to alleviate ACR-stimulated IPEC-J2 cell *** slightly activated nuclear factor erythroid 2-related factor 2(Nrf2)signaling and its target genes,but this activation could not reduce intestine cell damage.A_(1) and D-A_(1) could alleviate ACR-induced cell damage,but the effect was abrogated in cells transiently transfected with Nrf2 small interfering RNA(siRNA).Further investigation confirmed that A_(1) and D-A_(1) interacted with Ketch-like ECH-associated protein 1(Keapl),which boosted the stabilization of Nrf2,subsequently promoted the translocation of Nrf2 into the nucleus,and further increased the expression of antioxidant proteins,thereby inhibiting glutathione(GSH)consumption,maintaining redox balance and eventually alleviating ACR-induced cell ***,there was no difference between A_(1) and D-A_(1) treated groups,indicating that A_(1) can tolerate gastrointestinal digestion and may be a potential compound to limit the toxicity of ACR.

关键词： Procyanidin A_1 Digestive products Acrylamide Nuclear factor erythroid 2-related factor 2(Nrf2) Intestinal cell damage

Procyanidin Aand its digestive products inhibit acrylamide-induced IPEC-J2 cell damage: apoptosis and cell cycle arrest

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Food Science and Human Wellness 2024年

作者： Fangfang Yan Si Qin chengming wang Wolfram Weckwerth Qun Lu Rui Liu Lab of Food Function and Nutrigenomics， College of Food Science and Technology， Hunan Agricultural University College of Food Science and Technology， Huazhong Agricultural University Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University)， Ministry of Education Molecular Systems Biology， Department of Functional and Evolutionary Ecology， University of Vienna

Our previous study has demonstrated that procyanidin A1(A1) and its simulated digestive product (D-A1) can prevent acrylamide （ACR）-induced cytotoxicity in small intestine cells. However， the potential mechanism remains poorly understood. In this study， ACR treatment was found to increase the levels of 8-hydroxy-deoxyguanine （8-OHdG） and phosphorated histone H2AX (γH2AX)， two DNA damage markers， thereby resulting in cell cycle arrest in the G2/M phase; whereas both A1and D-A1could prevent the phosphorylation of ataxia telangiectasia mutated （ATM） and checkpoint kinase 2 （Chk2）， and then regulate the expression of G2/M phase-related proteins， finally maintaining normal cell cycle progression. Moreover， A1and D-A1could increase the B cell lymphoma 2 （Bcl-2）/Bcl2-associated X （Bax） ratio and decrease the expression of cleaved caspase-3 and cleaved caspase-9 proteins to alleviate ACR-induced cell apoptosis， which might be related to the inhibition of the mitogen-activated protein kinase （MAPK） pathway. More importantly， A1showed no remarkable variation in inhibitory effect before and after digestion， indicating that it can endure gastrointestinal digestion and may be a promising phytochemical to alleviate ACR-induced intestinal cell damage.

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Distal-scanning common path probe for optical coherence tomography

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Journal of Innovative Optical Health Sciences 2024年第3期17卷 84-92页

作者： Zhengyu Chen Bin He Zichen Yin Zhangwei Hu Yejiong Shi chengming wang Xiao Zhang Ning Zhang Linkai Jing Guihuai wang Ping Xue State Key Laboratory of Low-dimensional Quantum Physics and Department of Physics Tsinghua UniversityBeijingChina Frontier Science Center for Quantum Information BeijingChina Jinsp Company Limited BeijingChina Beijing Institute of Technology BeijingChina Institute of Forensic Science Ministry of Public Security BeijingChina Department of Neurosurgery Beijing Tsinghua Changgung HospitalSchool of Clinical Medicine and Institute of Precision MedicineTsinghua UniversityBeijingChina

In this paper,we present a distal-scanning common path probe for optical coherence tomography(OCT)equipped with a hollow ultrasonic motor and a simple and specially designed *** novel probe proves to be able to effectively circumvent polarization and dispersion mismatch caused by fiber motion and is more robust to a variety of interfering factors during the imaging process,experimentally compared to a conventional noncommon path ***,our design counteracts the attenuation of backscattering with depth and the fall-off of the signal,resulting in a more balanced signal range and greater imaging ***-domain OCT imaging of phantom and biological tissue is also demonstrated with a sensitivity of∼100dB and a lateral resolution of∼3μ*** low-cost probe offers simplified system configuration and excellent robustness,and is therefore particularly suitable for clinical diagnosis as one-off medical apparatus.

关键词： Common path optical coherence tomography endoscopic probe

基于简化有限集模型预测电流控制的五相PMSM统一容错控制

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中国电机工程学报 2024年第1期44卷 269-279,I0022页

作者：周华伟王成明孙大万刘正蒙陈前江苏大学电气信息工程学院江苏省镇江市212013

在五相永磁同步电机(permanent-magnet synchronous motor,PMSM)中,有限集模型预测容错控制(finite control set model predictive fault tolerant control,FCS-MPFTC)存在计算量大、电流谐波含量高等问题。因此,该文提出一种简化FCS-MPFTC来实现相开路和短路故障情况下的统一容错控制。首先,将模型预测电流控制的电流代价函数等效转化为电压代价函数,并采用无差拍方法通过电流模型计算出参考电压。然后,基于抑制三次谐波电流为0的原则合成虚拟电压矢量(virtual voltage vector,V^(3));通过重构V^(3)和扇区,以直接获得参考电压矢量对应的最优电压矢量。最后,对传统和简化FCS-MPFTC在开路和短路故障下进行对比实验。结果表明,所提策略能够有效减小故障后计算量、转矩脉动以及电流谐波含量。

关键词：永磁同步电机模型预测控制虚拟电压矢量容错控制无差拍控制

基于磁链相移原理的不对称交替极永磁辅助同步磁阻电机设计与分析

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电工技术学报 2024年第2期39卷 455-464页

作者：周华伟龙顺海江光耀王成明刘正蒙江苏大学电气信息工程学院镇江212013

传统永磁辅助同步磁阻电机(PMaSynRM)无法充分利用永磁转矩和磁阻转矩,该文提出一种新型不对称交替极永磁辅助同步磁阻电机(ACP-PMaSynRM)。基于永磁磁链相移原理,将交替极永磁阵列、不对称磁极和磁障相结合,实现永磁转矩和磁阻转矩的... 详细信息

传统永磁辅助同步磁阻电机(PMaSynRM)无法充分利用永磁转矩和磁阻转矩,该文提出一种新型不对称交替极永磁辅助同步磁阻电机(ACP-PMaSynRM)。基于永磁磁链相移原理,将交替极永磁阵列、不对称磁极和磁障相结合,实现永磁转矩和磁阻转矩的最大值在相同电流相位下叠加,不但提高了永磁转矩和磁阻转矩的利用率,增强了电机输出转矩能力,而且减少了永磁体用量。采用有限元法对比分析了传统和新型ACP-PMaSynRM的电磁性能,验证了所提电机拓扑的可行性。最后,制造了一台48槽14极样机并对其进行了实验验证。

关键词：永磁辅助同步磁阻电机交替极磁链相移最大转矩

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石墨电极棉线基微流体肼燃料电池

电池 2024年第2期54卷 180-184页

作者：郝大程王城铭李成勋宋超大连交通大学环境与化学工程学院辽宁大连116028

为找到性价比高且安全环保的供电设备,搭建以水合肼为燃料、石墨为电极以及棉线为流道材料的无催化剂微流体燃料电池(MFC),并进行性能测试。石墨管阳极、石墨棒阴极组合的MFC电化学性能最佳,电池于燃料浓度为0.075 mol/L、NaOH浓度为1.0... 详细信息

为找到性价比高且安全环保的供电设备,搭建以水合肼为燃料、石墨为电极以及棉线为流道材料的无催化剂微流体燃料电池(MFC),并进行性能测试。石墨管阳极、石墨棒阴极组合的MFC电化学性能最佳,电池于燃料浓度为0.075 mol/L、NaOH浓度为1.0 mol/L及电极距离为4 mm时,具有11.10μW/cm^(2)的最大功率密度和121.45μA/cm^(2)的电流密度。搭建的MFC具有材料简单、成本低且组装方便等特点,无需外部泵维持共层流,作为便携式设备具备集成化和小型化的潜力。

关键词：微流体燃料电池(MFC) 棉线基石墨电极水合肼功率密度电流密度

短视频视域下大学生主流意识形态认同的挑战与对策

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安徽水利水电职业技术学院学报 2024年第1期24卷 56-60页

作者：王成名丁辉安徽国防科技职业学院安徽六安237011

网络短视频是新时代大学生娱乐、休闲、学习的主要场域。碎片化信息、泛娱乐化内容、多元思潮交锋、西方意识形态精准渗透等因素,给大学生主流意识形态认同带来了诸多问题和挑战。通过加大平台监管,强化舆论引导,发挥思想引领,构建常态... 详细信息

网络短视频是新时代大学生娱乐、休闲、学习的主要场域。碎片化信息、泛娱乐化内容、多元思潮交锋、西方意识形态精准渗透等因素,给大学生主流意识形态认同带来了诸多问题和挑战。通过加大平台监管,强化舆论引导,发挥思想引领,构建常态机制的传播制高点,来不断增强网络短视频平台主流意识形态的主导性和权威性,提升大学生主流意识形态认同度。

关键词：网络短视频大学生主流意识形态认同挑战提升路径

N-doped carbon-stabilized PtCo nanoparticles derived from Pt@ZIF-67： Highly active and durable catalysts for oxygen reduction reaction

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Nano Research 2017年第9期10卷 3228-3237页

作者： Nana Du chengming wang Ran Long Yujie Xiong Hefei National Laboratory for Physical Sciences at the Microscale iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) School of Chemistry and Materials Science and National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei 230026 China School of Chemistry and Materials Engineering Fuyang Normal College Fuyang 236041 China

The development of catalysts with high activity and durability for the cathodic oxygen reduction reaction (ORR) in both alkaline and acidic media is important for improving the performance of the proton exchange membrane (PEM) fuel cells. This can be achieved by dispersing Pt-based alloy nanoparticles inside N-doped porous carbon frameworks. However, it still requires the development of a facile method towards synthesizing this unique hybrid structure. In this work, we demonstrate that N-doped carbon-stabilized PtCo nanoparticles (PtCo@NC) can be facilely synthesized via thermal decomposition of Pt-incorporated Co-based zeolitic imidazolate framework (Pt@ZIF-67). The thickness of the carbon framework can be optimized to enable excellent durability, in sharp contrast to a commercial Pt/C catalyst. The mass activities achieved by optimizing the thickness of the carbon framework are 0.80 and 0.82 A·mgPt –1 at 0.9 V vs. RHE in alkaline and acidic electrolytes, respectively, which are nearly 8 times greater than those of the Pt/C. This work provides an alternative approach to low-cost and high-performance catalysts for both alkaline and acidic fuel cells.

关键词： oxygen reduction reaction PtCo nanoparticles ZIF-67 N-doped carbon metal organic frameworks

Analysis and Application of Variable Conductance Heat Pipe Air Preheater

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Journal of Thermal Science 2011年第3期20卷 248-253页

作者： chengming Shi Yang wang Quan Liao Ying Yang College of Power Engineering Chongqing University Chongqing 400044 China

The heat transfer analysis of variable conductance heat pipe air preheater was carried out. The temperature trans-fer matrix was obtained for the air preheater that comprises several discrete heat transfer units with same or different heat transfer surface area in a parallel or counter flow mode. By using the temperature transfer matrix, the outlet fluid temperatures could be easily calculated for a given air preheater and inlet fluid temperatures. The active length of condenser in a variable conductance heat pipe is determined according to the flat interface model. With the same initial conditions, the comparisons between variable conductance heat-pipe air preheater and regular heat pipe air preheater has been analyzed and tested in terms of heat pipe wall temperature, heat transfer surface area and outlet fluid temperatures. Based on the real industrial applications, it has been confirmed that the variable conductance heat pipe air preheater has excellent performance of anti-corrosion and anti-ash-deposition especially at the variable working condition and the sulfur coal (5%-6% mass fraction of sulfur) condition.

关键词： variable conductance heat pipe air preheater anti-corrosion anti-ash deposition

Heat Transfer Effectiveness of Three-Fluid Separated Heat Pipe Exchanger

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Journal of Thermal Science 2011年第1期20卷 64-69页

作者： chengming Shi Yang wang Ying Yang Quan Liao College of Power Engineering Chongqing University Chongqing 400044 China

A heat transfer model for three-fluid separated heat pipe exchanger was analyzed,and the temperature transfer matrix for general three-fluid separated heat exchanger working in parallel-flow or counter-flow mode was *** was found that the forms of temperature transfer matrix are similar for heat pipe rows with equal or different heat transfer surface ***,by using the temperature transfer matrix of the heat pipe exchanger,the relationship between heat transfer effectiveness θ 1,θ 2 and M,NTU,U,Δt i were derived for the exchanger operating in parallel-flow or counter-flow mode,and a simple special example was adopted to demonstrate the correctness of these relationships.

关键词： heat pipes three-fluid heat exchangers heat transfer effectiveness temperature transfer matrix