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Science China(Information Sciences) 2023年第9期66卷 35-49页

作者： chengcheng fu Hao ZHANG Chao HUANG Zhuping WANG Huaicheng YAN School of Electronic and Information Engineering Tongji University School of Information Science and Engineering East China University of Science and Technology

This paper investigates the cooperative output regulation problem of heterogeneous linear parameter-varying multi-agent systems under denial-of-service(DoS) attacks. The matrix and state of the exosystem are taken to be unknown to the followers. Moreover, with the assumption that only a directed spanning tree exists in the communication topology, a resilient observer is proposed to exponentially estimate the global information, which can also be effective under DoS attacks with a certain intensity. Afterward,to avoid using the exact value of the exosystem matrix, a distributed online algorithm is proposed, through which the linear parameter-varying output regulation equation is asymptotically solved. Based on the resilient observer and the solution of the output regulation equation, a distributed regulator is proposed to achieve asymptotic cooperative output regulation for all agents. Some numerical simulations are conducted to verify the effectiveness of the proposed observer, algorithm, and controller.

关键词： cooperative output regulation heterogeneous multi-agent systems DoS attacks linear parameter-varying systems

The lithium and sodium storage performances of phosphorus and its hierarchical structure

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Nano Research 2019年第1期12卷 1-17页

作者： Dan Zhao Lihui Zhang chengcheng fu Jinying Zhang Chunming Niu Center of Nanomaterials for Renewable Energy State Key Laboratory of Electrical Insulation and Power EquipmentSchool of Electrical EngineeringXi'an Jiaotong UniversityXi'an 710054China

Recent preparation of black phosphorene and subsequent discovery of its excellent optical and electronic properties have attracted great attenti on,and ren ewed interest to *** nt researches have indicated that phosphorus structures are promisi ng an odes for lithium-ion and sodium-ion batteries.A high theoretical capacity of 2,596 mAh·g^-1 was predicted for phosphorus according to the reaction of 3Li/Na+P→Li3P/***,fast capacity degradation is accompanying with most phosphorus structures due to the low electronic conductivity and structural pulverization induced by large volume change in charging and discharging *** electrochemical performances are significantly affected by the hierarchical structural design of phosphorus.A few reviews of phosphorus structures have been reported recent?However,no review about the electrochemical performances of phosphorus structures according to their hierarchical structures has been *** of all,phosphrus allotropes along with their structure and fundamental properties are briefly reviewed in this ***,the studies on lithiation/sodiation mechanism of red/black phosphorus are ***,a summary about the electrochemical performances of red/black phosphorus composites with different hierarchical structures is ***,the,development challenges and future perspectives of phosphorus structures as anodes for LIBs and SIBs are discussed.

关键词： lithium ion batteries sodium ion batteries phosphorus composites phosphorus structures review

Rock-salt and helix structures of silver iodides under ambient conditions

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National Science Review 2019年第4期6卷 767-774页

作者： Hongyang Huang Jinying Zhang Yifan Zhang chengcheng fu Jialiang Huang Yonghong Cheng Chunming Niu Xinluo Zhao Hisanori Shinohara State Key Laboratory of Electrical Insulation and Power Equipment Center of Nanomaterials for Renewable Energy (CNRE) School of Electrical EngineeringXi'an Jiaotong University Department of Physics Shanghai University Department of Chemistry and Institute for Advanced Research Nagoya University

Many different phase structures have been discovered for silver iodides. The β and γ phases were found to be the most common ones at ambient conditions, while the rock-salt phase was found to be stable under pressures between 400 MPa and 11.3 GPa. Recently, the α phase was demonstrated to be stable under ambient conditions when the particle sizes were reduced to below 10 nm. However, no other phase has been reported to be stable for silver iodides under ambient conditions. Rock-salt and helix structures have been found to be stable under ambient conditions in this study. The structures have been characterized by elemental mapping, Raman scattering, and high-resolution transmission electron microscopy. The stabilities of these structures were also confirmed by molecular dynamics and density functional theory.

关键词： carbon nanotubes silver iodides rock salt helix ambient conditions

Nanopriming with selenium doped carbon dots improved rapeseed germination and seedling salt tolerance

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The Crop Journal 2024年第5期12卷 1333-1343页

作者： Mohammad Nauman Khan chengcheng fu Xiaohui Liu Yanhui Li Jiasen Yan Lin Yue Jiaqi Li Zaid Khan Lixiao Nie Honghong Wu National Key Laboratory for Germplasm Innovation&Utilization of Horticultural Crops MOA Key Laboratory of Crop Ecophysiology and Farming System in the Middle Reaches of the Yangtze RiverThe Center of Crop NanobiotechnologyHuazhong Agricultural UniversityWuhan 430070HubeiChina Hubei Hongshan Laboratory Wuhan 430070HubeiChina School of Breeding and Multiplication(Sanya Institute of Breeding and Multiplication) Hainan UniversitySanya 572000HainanChina College of Food and Pharmaceutical Engineering Guizhou Institute of TechnologyGuiyang 550003GuizhouChina College of Natural Resources and Environment South China Agricultural UniversityGuangzhou 510642GuangdongChina Shenzhen Institute of Nutrition and Health Huazhong Agricultural UniversityShenzhen 511464GuangdongChina Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 511464GuangdongChina

Soil salinity is a big environmental issue affecting crop *** seed nanopriming has been widely used to improve seed germination and seedling growth under salinity,our knowledge about the underlying mechanisms is still ***,we newly synthesized selenium-doped carbon dots nanoparticles coated with poly acrylic acid(poly acrylic acid coated selenium doped carbon dots,PAA@Se-CDs)and used it to prime seeds of *** TEM(transmission electron microscope)size and zeta potential of PAA@Se-CDs are 3.8±0.2 nm and-30 mV,*** 8 h priming,the PAA@Se-CDs nanoparticles were detected in the seed compartments(seed coat,cotyledon,and radicle),while no such signals were detected in the NNP(no nanoparticle control)group(SeO_2 was used as the NNP).Nanopriming with PAA@Se-CDs nanoparticles increased rapeseeds germination(20%)and seedling fresh weight(161%)under saline conditions compared to NNP ***@Se-CDs nanopriming significantly enhanced endo-β-mannanase activities(255%increase,21.55μmol h^(-1)g^(-1)vs.6.06μmol h^(-1)g^(-1),at DAS 1(DAS,days after sowing)),total soluble sugar(33.63 mg g^(-1)FW(fresh weight)vs.20.23 mg g^(-1)FW)and protein contents(1.96μg g^(-1)FW vs.1.0μg g^(-1)FW)to support the growth of germinating seedlings of rapeseeds under salt stress,in comparison with NNP co *** respiration rate and ATP content were increased by 76%and 607%,*** oxidative damage of salinity due to the overaccumulation of reactive oxygen species(ROS)was alleviated by PAA@Se-CDs nanopriming by increasing the antioxidant enzyme activities(SOD(superoxide dismutase),POD(peroxidase),and CAT(catalase)).Another mechanism behind PAA@Se-CDs nanopriming improving rapeseeds salt tolerance at seedling stage was reducing sodium(Na^(+))accumulation and improving potassium(K^(+))retention,hence increasing the K^(+)/Na^(+)ratio under saline ***,our results not only showed that seed nanopriming with PAA@Se-CDs could be a

关键词： PAA@Se-CDs Nanopriming Salt stress Antioxidant system K^(+)/Na^(+) balance ATP production

嵌合抗原受体T细胞对多发性骨髓瘤现有治疗模式的挑战

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中华内科杂志 2020年第7期59卷 495-497页

作者：傅琤琤苏州大学附属第一医院血液科 215006

多发性骨髓瘤(MM)是一种血液系统的恶性克隆浆细胞增殖性肿瘤,多发于老年。近20年,MM治疗观念不断更新,药物研发发展迅速,新型机制的药物取代了传统化疗,极大改善了患者预后,使患者总生存期明显延长。在新药中,免疫治疗成为肿瘤治疗的... 详细信息

多发性骨髓瘤(MM)是一种血液系统的恶性克隆浆细胞增殖性肿瘤,多发于老年。近20年,MM治疗观念不断更新,药物研发发展迅速,新型机制的药物取代了传统化疗,极大改善了患者预后,使患者总生存期明显延长。在新药中,免疫治疗成为肿瘤治疗的主要突破点,除了第1个有效的抗CD38单克隆抗体进入临床应用外,嵌合抗原受体T细胞(CAR-T)成为治疗难治复发MM的新免疫疗法,对MM现有治疗模式发起挑战。

关键词：多发性骨髓瘤嵌合抗原受体T细胞挑战

fully Distributed Event-triggered Cooperative Output Regulation of Linear Parameter-varying Systems

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Fully Distributed Event-triggered Cooperative Output Regulat...

《中国多发性骨髓瘤诊治指南(2024年修订)》微小残留病疗效标准部分解读

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作者： chengcheng fu Hao Zhang Zhuping Wang Department of Control Science and Engineering Tongji University Shanghai Research Institute for Intelligent Autonomous Systems Tongji University

The cooperative output regulation problem of linear parameter-varying multi-agent systems via fully distributed eventtriggered adaptive control is studied in this paper. It is assumed that agents cannot communicate with each other continuously. To solve this problem, a fully distributed event-triggered adaptive controller is designed such that the problem studied in this paper can be solved properly.

关键词： Event-triggered control distributed control cooperative output regulation linear parameter-varying multi-agent system

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中华内科杂志 2024年第12期63卷 1179-1182页

作者：常英军傅琤琤北京大学人民医院北京大学血病研究所国家血液系统临床医学研究中心造血干细胞移植治疗血液病北京市重点实验室北京100044 苏州大学附属第一医院江苏省血液研究所国家血液系统临床医学研究中心卫生部血栓与止血重点实验室苏州215006

《中国多发性骨髓瘤诊治指南(2024年修订)》关于微小残留病(MRD)疗效标准部分仍参照2016年发表在《柳叶刀》上的国际骨髓瘤工作组(IMWG)多发性骨髓瘤(MM)疗效和MRD评估共识。近年来的研究证实MRD持续阴性较单一时间点MRD阴性能更好地预... 详细信息

《中国多发性骨髓瘤诊治指南(2024年修订)》关于微小残留病(MRD)疗效标准部分仍参照2016年发表在《柳叶刀》上的国际骨髓瘤工作组(IMWG)多发性骨髓瘤(MM)疗效和MRD评估共识。近年来的研究证实MRD持续阴性较单一时间点MRD阴性能更好地预测MM患者的预后,并且MRD已经成为临床试验中无疾病进展生存和总体生存的替代终点,此外,MRD指导的MM个体化治疗也显示出良好的疗效,使患者获得治愈成为可能。然而,MM患者MRD检测方法及其在疗效评估方面仍存在一些亟待解决的问题,需要血液科医生在实际临床工作中给予足够的重视。

关键词：多发性骨髓瘤微小残留病替代终点个体化治疗

Telomerase activity in myelodysplastic syndrome

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Chinese Medical Journal 2002年第10期115卷 1475-1478页

作者：傅争争陈子兴苏州大学附属第一医院江苏省血液研究所，苏州215006

OBJECTIVE: To study telomerase activity (TA) and its variation in bone marrow mononuclear cells from patients with myelodysplastic syndrome (MDS) at different stages in comparison with normal bone marrow cells and leukemic cells. METHODS: The TA was semi-quantitatively determined in mononuclear cells from 20 normal bone marrow samples, 21 patients with MDS at different stages and 32 cases of acute leukemia by using a polymerase chain reaction-enzyme linked immuno-sorben assay (PCR-ELISA) kit. RESULTS: The TA in normal bone marrow cells was in the range of 0 to 0.3 units (U) with a mean of 0.11 +/- 0.08 U. Among them, 3 samples were considered positive in accordance with the standard recommended by the kit's pamphlet. In bone marrow cells from patients with acute leukemia, the TA was ranging from 0 to 0.96 U with a mean value of 0.42 +/- 0.26 U. The positive rate was 78.1% which was significantly different from that in normal bone marrow (BM) (P

关键词： Adolescent Adult Bone Marrow Cells Child Female Humans Leukocytes, Mononuclear Male Middle Aged Myelodysplastic Syndromes Research Support, Non-U.S. Gov't Telomerase

《基于骨髓样本的多发性骨髓瘤微小残留病灶检测专家共识(2024年版)》解读

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临床血液学杂志 2024年第9期37卷 607-611页

作者：傅琤琤苏州大学附属第一医院血液科江苏苏州215006

多发性骨髓瘤(multiple myeloma,MM)是血液系统第二大常见恶性肿瘤,标准的整体治疗模式及新药为主的方案极大地改善了MM患者的生存,但微小残留病灶(minimal residual disease,MRD)的存在可导致绝大多数患者的复发。目前,二代流式细胞术(... 详细信息

多发性骨髓瘤(multiple myeloma,MM)是血液系统第二大常见恶性肿瘤,标准的整体治疗模式及新药为主的方案极大地改善了MM患者的生存,但微小残留病灶(minimal residual disease,MRD)的存在可导致绝大多数患者的复发。目前,二代流式细胞术(next-generation flow cytometry,NGF)和二代测序(next-generation sequencing,NGS)是基于骨髓样本检测MM患者MRD的主流技术。为了推进MM患者MRD检测技术的标准化和规范化,中华医学会血液学分会实验诊断学组及浆细胞疾病学组、中国医师协会多发性骨髓瘤专业委员会讨论制订了在MM患者中应用NGF和NGS技术进行MRD检测的中国专家共识。为更好地指导临床实践,本文拟对共识的临床和实验室部分进行解读。

关键词：多发性骨髓瘤骨髓微小残留病灶二代流式细胞术二代测序

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压电加速度传感器有限元仿真方法研究

压电与声光 2021年第1期43卷 5-9,15页

作者：傅成城高成黄姣英张卫方北京航空航天大学能源与动力工程学院北京100191 北京航空航天大学可靠性与系统工程学院北京100191

压电加速度传感器具有频带宽,结构简单,耐高温性能好等特点,在复杂机械应力和高温应力环境下应用广泛,是航空发动机健康监测、爆炸冲击监测等应用下必不可缺的器件。对于压电加速度传感器的设计和研究,常使用有限元仿真法来分析其固有... 详细信息

压电加速度传感器具有频带宽,结构简单,耐高温性能好等特点,在复杂机械应力和高温应力环境下应用广泛,是航空发动机健康监测、爆炸冲击监测等应用下必不可缺的器件。对于压电加速度传感器的设计和研究,常使用有限元仿真法来分析其固有频率、响应及在此基础上的各种机械应力、温度应力下的状态。从压电加速度传感器的原理、结构和有限元仿真的基本流程出发,调研了压电加速度传感器有限元仿真中的主要问题。按照不同结构类型总结了建立几何模型时的结构简化方法,分析了螺栓预紧力的主要仿真方法;区分部分仿真和整体仿真,总结了固有频率的仿真方法;按照不同激励,讨论了不同应力的仿真实现方法。

关键词：有限元仿真压电加速度传感器结构简化螺栓预紧力固有频率应力仿真