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Rational Design of a Near-infrared Fluorescent Material with High Solid-state Efficiency,Aggregation-induced Emission and Live Cell Imaging Property

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Chemical Research in Chinese Universities 2022年第6期38卷 1461-1466页

作者： SHANG Anqi ZHAO Lele LI Zhenhua cheng zhuang JIN Haixu FENG Zijun CHEN Zhijun ZHANG Haiquan lu Ping State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun130012P.R.China State Key Laboratory of Metastable Materials Science and Technology Yanshan UniversityQinhuangdao066004P.R.China

Near-infrared(NIR)fluorescent materials with high photoluminescent quantum yields(PLQYs)have wide application ***,we design and synthesize a D-A type NIR organic molecule,TPATHCNE,in which triphenylamine and thiophene are utilized as the donors and fumaronitrile is applied as the *** systematically investigate its molecular structure and photophysical *** shows high T_(g) of 110℃ and T_(d) of 385℃ and displays an aggregation-induced emission(AIE)property.A narrow optical bandgap of 1.65 eV is *** non-doped film of TPATHCNE exhibits a high PLQY of 40.3%with an emission peak at 732 nm,which is among the best values of NIR *** TPATHCNE is applied in organic light-emitting diode(OLED),the electroluminescent peak is located at 716 nm with a maximum external quantum efficiency of 0.83%.With the potential in cell imaging,the polystyrene maleic anhydride(PMSA)modified TPATHCNE nanoparticles(NPs)emit strong fluorescence when labeling HeLa cancer cells,suggesting that TPATHCNE can be used as a fluorescent carrier for specific staining or drug delivery for cellular *** NPs fabricated by bovine serum protein(BSA)are cultivated with mononuclear yeast cells,and the intense intracellular red fluorescence indicates that it can be adopted as a specific stain for imaging.

关键词： Near-infrared emission Aggregation-induced emission High solid-state efficiency Organic light-emitting diode

Numerical Investigation on Dynamics of the Tendon System of A TLP by Applying Absolute Nodal Coordinate Formulation

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China Ocean Engineering 2021年第3期35卷 384-397页

作者： luu Quang HUNG KANG zhuang ZHANG cheng JIE Li-shao College of Shipbuilding Engineering Harbin Engineering UniversityHarbin 150001China Office of Planning and Investment Saodo UniversityHai DuongVietnam

In the present study,the dynamics of the tendon system of a tension-leg platform(TLP)is investigated through the absolute nodal coordinate formulation(ANCF).Based on the energy conversion principle,the stiffness,generalized elastic force,external load and mass matrices of the element are deduced to perform the element assembling by using the finite element *** the motion equation of the tendon/riser is *** this study,the TLP in the International Ship Structures Committee(ISSC)model under the first and second wave forces is considered as the case *** simulation is performed in the MATLAB ***,the accuracy and reliability of the programs are verified for cases of beam model with theoretical *** is found that the motion response of tendons is affected by the TLP movement and environmental load,***,the motion response is calculated using the SESAM software and exported as the boundary of ANCF ***,the static and dynamic characteristics of the four tendons of ISSC TLP are analyzed systematically by the ANCF *** analysis proves the effectiveness and feasibility of the ANCF *** is concluded that the proposed method is a powerful scheme for calculating the dynamics of tendon/riser in the field of ocean engineering.

关键词： Absolute nodal coordinate formulation(ANCF) tendon/riser TLP platform large deformation top and middle nodes wave direction

Numerical simulations of FPSO with sloshing tanks in a random freak waves

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Journal of Hydrodynamics 2022年第3期34卷 491-498页

作者： Yuan zhuang Guo Wang De-cheng Wan Jian-wei Wu Computational Marine Hydrodynamics Lab(CMHL) School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai200240China Marine Design and Research Institute of China Shanghai200011China Wuhan Second Ship Design and Research Institute Wuhan430205China

This paper presents a potential-viscous coupled method to simulate a floating production storage and offloading(FPSO)with two liquefied natural gas(LNG)sloshing tanks in a random freak *** potential theory uses high-order-spectral(HOS)*** random wave is generated by HOS for 2000 s,and a freak wave is observed around 1830 *** FPSO LNG model was firstly verified in regular waves using HOS-computational fluid dynamics(CFD)coupled method and validated the HOS-CFD coupled method can solve the ship motion coupled with sloshing tanks *** FPSO with LNG tanks are then simulated in the freak wave,showed the coupling effects when the freak wave *** the existence of the sloshing tanks,the amplitude of the roll motion decreases and the period of roll motion *** breaking phenomenon can be observed when the wave crest of the freak wave encounters with the ship.

关键词： Ship motion with sloshing tank high-order-spectral-computational fluid dynamics(HOS-CFD)method naoe-FOAM-SJTU solver freak waves

Intestinal Microbiota in Early Life and Its Implications on Childhood Health

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Genomics, Proteomics & Bioinformatics 2019年第1期17卷 13-25页

作者： lu zhuang Haihua Chen Sheng Zhang Jiahui zhuang Qiuping Li Zhichun Feng Affiliated Bayi Children's Hospital The Seventh Medical Center of PLA General Hospital National Engineering Laboratory for Birth Defects Prevention and Control of Key Technology Beijing Key Laboratory of Pediatric Organ Failure The First Clinical Academy of Dalian Medical University College of the Environment Northeast Normal University

Trillions of microbes reside in the human body and participate in multiple physiological and pathophysiological processes that affect host health throughout the life cycle. The microbiome is hallmarked by distinctive compositional and functional features across different life *** evidence has shown that microbes residing in the human body may play fundamental roles in infant development and the maturation of the immune system. Gut microbes are thought to be essential for the facilitation of infantile and childhood development and immunity by assisting in breaking down food substances to liberate nutrients, protecting against pathogens, stimulating or modulating the immune system, and exerting control over the hypothalamic–pituitary–adrenal *** review aims to summarize the current understanding of the colonization and development of the gut microbiota in early life, highlighting the recent findings regarding the role of intestinal microbes in pediatric diseases. Furthermore, we also discuss the microbiota-mediated therapeutics that can reconfigure bacterial communities to treat dysbiosis.

关键词： Intestinal microbiota Immunity Gut-brain axis Early life Diseases Microbiota manipulation

Sampled-Data H_(∞)Dynamic Output Feedback Controller Design for Fuzzy Markovian Jump Systems

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Journal of Systems Science & Complexity 2023年第1期36卷 239-256页

作者： LIN Yuqian zhuang Guangming XIA Jianwei CHEN Guoliang lu Junwei School of Mathematical Sciences Liaocheng UniversityLiaocheng 252059China School of Electrical and Automation Engineering Nanjing Normal UniversityNanjing 210094China

This paper considers the issue of H_(∞)dynamic output feedback controller design for T-S fuzzy Markovian jump systems under time-varying sampling with known upper bound on the sampling *** main aim is to realize sampled-data fuzzy dynamic output feedback control so as to demonstrate the stochastic stability and H_(∞)performance index of the closed-loop sampled-data fuzzy Markovian jump ***,by making the most of the information within the sampling interval,a suitable closed-loop function is constructed and the integral terms are handled by using free weighted matrix method and improved integral inequality *** example and single-link robot arm are presented to show the effectiveness of the developed method.

关键词： Dynamic output feedback control fuzzy Markovian jump systems H_(∞)control sampleddata control stochastic stability

Imaging mechanical shear waves induced by piezoelectric ceramics in magnetic resonance elastography

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Chinese Science Bulletin 2006年第6期51卷 755-760页

作者： CHEN Jun NI cheng zhuang Tiange Department of Biomedical Engineering Shanghai Jiao Tong University Shanghai 200030 China Siemens Mindit Magnetic Resonance Ltd. Shenzhen 518057 China

Magnetic Resonance Elastography (MRE) is a noninvasive technique to measure elas-ticity of tissues in vivo. In this paper, a mechanical shear wave MR imaging system experiment is set for MRE. A novel actuator is proposed to generate me-chanical shear waves propagating inside a gel phantom. The actuator is made of piezoelectric ce-ramics, and fixed on a plexiglass bracket. Both of the gel phantom and the actuator are put into a head coil inside the MR scanner’s bore. The actuator works synchronously with an MR imaging sequence running on the MR scanner. The sequence is modified from a FLASH sequence into a motion-sensitizing phase- contrast sequence for shear wave MR imaging. Shear wave images are presented, and these effects on the shear wave MR imaging system, including the stiffness of phantoms, the frequency of the actuator, the parameters of the motion-sensitizing gradient, and the oscillation of the patient bed, are discussed.

关键词：磁共振成像压电陶瓷序列设计成像机制剪力波生物医学

Substrate orientation effect in covalent organic frameworks/2D materials heterostructure by high-resolution atomic force microscopy

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Nano Research 2023年第7期16卷 10047-10052页

作者： lu Wang cheng lu Huijuan Yan Dong Wang CAS Key Laboratory of Molecular Nanostructure and Nanotechnology CAS Research/Education Center for Excellence in Molecular SciencesBeijing National Laboratory for Molecular Science(BNLMS)Institute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

Heterostructures based on covalent organic frameworks(COFs)and other two-dimensional(2D)materials attract considerable attention due to their extraordinary properties and tremendous application *** effects play a crucial role in the integration of ultrathin COF films onto 2D materials through direct *** this study,highly ordered monolayer COFs were successfully constructed on the surfaces of highly oriented pyrolytic graphite(HOPG),hexagonal boron nitride(hBN),and molybdenum disulfide(MoS_(2)).High-resolution atomic force microscopy(HR-AFM)imaging clearly reveals the substrate orientation effect in COFs/2D materials *** networks formed via Schiff-base reaction and boronic acid condensation reaction can epitaxially grow in specific orientations relative to the underlying substrate *** work provides direct evidence for substrate effects in the on-surface synthesis of COFs and paves the way for further investigation into the intrinsic electronic properties of monolayer COFs and the development of multifunctional hybrid devices.

关键词： substrate orientation effect covalent organic frameworks(COFs) on-surface synthesis high-resolution atomic force microscopy(HR-AFM)

Numerical investigation on cooling performance of filter in a pyrotechnic gas generator

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Defence Technology（防务技术） 2021年第2期17卷 343-351页

作者： cheng cheng Xiaobing Zhang Chong Wang lu Wang School of Energy and Power Engineering Nanjing University of Science and TechnologyNanjing210094China

As a key part of the pyrotechnic gas generator,the filter not only removes the particulate matter but also cools the hot gas to a safe *** paper aims to improve the understanding of the basic heat and flow phenomenon in the gas *** pyrotechnic gas generator is modelling by a simplified filter structure with fiber arrays.A finite-volume model of the heat and fluid flow is proposed to simulate the detailed multi-dimensional flow and energy conversion *** verification results are in good agreement with data in different *** results demonstrate that the filter can not only absorb heat from the gas but also cause the high intensity enhancement of the heat *** performance difference between inline and staggered arrays is also *** findings of the study put a further prediction tool for the understanding and design of the filter system with fibers.

关键词： Pyrotechnic gas generator Cooling performance Filter Metal fiber

NUMERICAL STUDY FOR NONLINEAR EVOluTION OF VORTEX SHEET AND ITS APPLICATIONS: PART I. APPROACH AND PERIODICAL EVOluTION OF VORTEX SHEET

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Journal of Hydrodynamics 2000年第2期12卷 1-10页

作者： Wang, Xunye lu, Xiyun zhuang, Lixian Zhu, Keqin Univ of Science and Technology of China Hefei China

The superconvergence of Multhopp′s discretization for the solution to the normal wash integral equation for the flow past a curved plate was theoretically analyzed and numerically examined. The Multhopp′s discretization also has a superconvergence behavior in simulating the vortex sheet evolution. An improved Multhopp′s method was suggested and applied to the numerical simulation of a periodical evolution of a flat vortex sheet. To validate the results obtained by the inviscid vortex method, the initial-value problem for the development of a shear layer at large Reynolds number was numerically investigated by solving the two-dimensional incompressible Navier-Stokes equations.

关键词： Computer simulation Convergence of numerical methods Integral equations Reynolds number Two dimensional