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World Journal of Traditional Chinese Medicine 2016年第2期 89-90页

作者： Ying-li Zhu Lin-yuan wang Jing-xia wang Zhi-hui Yang cheng-long wang Zi-chen wang Li Wu Jian-jun Zhang Beijing University of Chinese Medicine Department of Psychiatry & Neuroscience University of Florida

Introduction:Albiflorin(AF),a monoterpene glycoside isolated from ***,possess a variety of pharmacological activities,especially on psychiatric *** study investigated whether AF(1m M,0.5

关键词： ROS NO NEUROPROTECTIVE EFFECTS OF ALBIFLORIN AGAINST CORTICOSTERONE-INDUCED NEUROTOXICITY IN PC12 CELLS VIA NO/ROS SIGNAL PATHWAY PC

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钨中氘氦行为的高分辨热脱附谱实验方法研究

原子能科学技术 2018年第6期52卷 1049-1055页

作者：傅青伟程龙王军袁悦吕广宏北京航空航天大学北京100191

氢同位素在材料中的扩散、捕获和滞留等行为可通过热脱附谱实验方法进行研究。为实现对同时含有氘氦的钨材料进行热脱附测量并研究钨中氘氦滞留行为,搭建了1套基于高分辨四极质谱仪的热脱附实验系统HiTDS。HiTDS实现了1.2×10^(-6) Pa... 详细信息

氢同位素在材料中的扩散、捕获和滞留等行为可通过热脱附谱实验方法进行研究。为实现对同时含有氘氦的钨材料进行热脱附测量并研究钨中氘氦滞留行为,搭建了1套基于高分辨四极质谱仪的热脱附实验系统HiTDS。HiTDS实现了1.2×10^(-6) Pa的高本底真空度,速率为1K/s的精确线性升温,最高加热温度达1 423K,能准确测量样品中气体元素的脱附速率和脱附量。通过配备高分辨四极质谱仪,HiTDS可快速分辨氘氦元素并测量其脱附速率。HiTDS经过调谐校准、标定系数标定后,对氘氦等离子体辐照钨样品进行了热脱附测量。测得的氘氦热脱附谱显示,纯氘脱附量与剂量正相关,而氦的引入显著抑制氘滞留并使其趋于饱和。热脱附实验结果与类似辐照条件的其他研究成果基本一致,检验了该实验方法的有效性。

关键词：氘氦热脱附高分辨

Glutamatergic CYLD deletion leads to aberrant excitatory activity in the basolateral amygdala:association with enhanced cued fear expression

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Neural Regeneration Research 2025年第11期20卷 3259-3272页

作者： Huidong Li Faqin Li Zhaoyi Chen Erwen Wu Xiaoxi Dai Danni Li Haojie An Shiyi Zeng Chunyan wang Li Yang cheng long School of Life Sciences South China Normal UniversityGuangzhouGuangdong ProvinceChina School of Life Sciences Guangzhou UniversityGuangzhouGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Major Obstetric Diseases The Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina South China Normal University-Panyu Central Hospital Joint Laboratory of Translational Medical Research Panyu Central HospitalGuangzhouGuangdong ProvinceChina

Neuronal activity,synaptic transmission,and molecular changes in the basolateral amygdala play critical roles in fear ***(CYLD)is a deubiquitinase that negatively regulates the nuclear factor kappa-B *** is well studied in non-neuronal cells,yet underinvestigated in the brain,where it is highly *** studies have shown involvement of CYLD in the remodeling of glutamatergic synapses,neuroinflammation,fear memory,and anxiety-and autism-like ***,the precise role of CYLD in glutamatergic neurons is largely ***,we first proposed involvement of CYLD in cued fear *** next constructed transgenic model mice with specific deletion of Cyld from glutamatergic *** results show that glutamatergic CYLD deficiency exaggerated the expression of cued fear in only male ***,loss of CYLD in glutamatergic neurons resulted in enhanced neuronal activation,impaired excitatory synaptic transmission,and altered levels of glutamate receptors accompanied by over-activation of microglia in the basolateral amygdala of male ***,our study suggests a critical role of glutamatergic CYLD in maintaining normal neuronal,synaptic,and microglial *** may contribute,at least in part,to cued fear expression.

关键词： basolateral amygdala cued fear expression cylindromatosis deubiquitinase glutamate receptor 1 glutamatergic neuron microglial activation N-methyl-D-aspartate receptor 1 neuronal activation synaptic transmission

Crystallization Modulation and Holistic Passivation Enables Efficient Two‑Terminal Perovskite/CuIn(Ga)Se_(2)Tandem Solar Cells

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Nano-Micro Letters 2025年第1期17卷 205-215页

作者： Cong Geng Kuanxiang Zhang Changhua wang Chung Hsien Wu Jiwen Jiang Fei long Liyuan Han Qifeng Han Yi‑Bing cheng Yong Peng State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Science and Engineering Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-terminal(2-T)perovskite(PVK)/CuIn(Ga)Se_(2)(CIGS)tandem solar cells(TSCs)have been considered as an ideal tandem cell because of their best bandgap matching regarding to Shockley–Queisser(S–Q)***,the nature of the irregular rough morphology of commercial CIGS prevents people from improving tandem device *** this paper,D-homoserine lactone hydrochloride is proven to improve coverage of PVK materials on irregular rough CIGS surfaces and also passivate bulk defects by modulating the growth of PVK *** addition,the minority carriers near the PVK/C60 interface and the incompletely passivated trap states caused interface recombination.A surface reconstruction with 2-thiopheneethylammonium iodide and N,N-dimethylformamide assisted passivates the defect sites located at the surface and grain ***,LiF is used to create this field effect,repelling hole carriers away from the PVK and C60 interface and thus reducing *** a result,a 2-T PVK/CIGS tandem yielded a power conversion efficiency of 24.6%(0.16 cm^(2)),one of the highest results for 2-T PVK/CIGS TSCs to our *** validation underscores the potential of our methodology in achieving superior performance in PVK/CIGS tandem solar cells.

关键词： PVK/CIGS TSCs Irregular rough surfaces Modulating the growth PVK/C60 interface recombination

Sporadic E responds to the 2022 Tonga volcano eruptions recorded by the Meridian Project

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Earth and Planetary Physics 2025年第1期9卷 20-28页

作者： YangYi Sun Tao Yu Jin wang Chi long School of Geophysics and Geomatics China University of Geosciences(Wuhan)Wuhan 430047China School of Physics and Electronic Science Guizhou Normal UniversityGuizhou 550001China

In this study,ionosonde observations over Fuke(19.5°N,109.1°E),Wuhan(30.5°N,114.4°E),and Mohe(53.5°N,122.3°E)were analyzed to demonstrate the responses of the sporadic E()to the severe atmospheric disturbances caused by the Tonga volcanic eruptions on January 15,*** most prominent signature was the disappearance of the layer after~10:00 UT over Wuhan and Fuke,which was attributed to the vertical drift caused by the *** occurred intermittently after 13:00 UT following the arrival of the tropospheric Lamb *** examine the causal mechanism for the intermittence,we also included data of horizontal winds in the mesosphere and lower thermosphere region recorded by the meteor radars at Wuhan and Mohe in this *** wind disturbances with periods of~20 hours contributed to the formation of the layer in the nighttime on January 15.

关键词： sporadic E Tonga eruptions neutral wind disturbances

MoS_(2)Lubricate‑Toughened MXene/ANF Composites for Multifunctional Electromagnetic Interference Shielding

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Nano-Micro Letters 2025年第2期17卷 358-371页

作者： Jiaen wang Wei Ming longfu Chen Tianliang Song Moxi Yele Hao Zhang long Yang Gegen Sarula Benliang Liang Luting Yan Guangsheng wang School of Physical Science and Engineering Beijing Jiaotong UniversityBeijing 100044People’s Republic of China Key Laboratory of Bio‑Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191People’s Republic of China

The design and fabrication of high toughness electromagnetic interference(EMI)shielding composite films with diminished reflection are an imperative task to solve electromagnetic pollution *** MXene/ANF(aramid nanofibers)–MoS_(2)composite films with nacre-like layered structure here are fabricated after the introduction of MoS_(2)into binary MXene/ANF composite *** introduction of MoS_(2)fulfills an impressive“kill three birds with one stone”improvement effect:lubrication toughening mechanical performance,reduction in secondary reflection pollution of electromagnetic wave,and improvement in the performance of photothermal *** the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 50:50),the strain to failure and tensile strength increase from 22.1±1.7%and 105.7±6.4 MPa and to 25.8±0.7%and 167.3±9.1 MPa,*** toughness elevates from 13.0±4.1 to 26.3±0.8 MJ m^(−3)(~102.3%)*** the reflection shielding effectiveness(SE_(R))of MXene/ANF(mass ratio of 50:50)decreases~10.8%.EMI shielding effectiveness(EMI SE)elevates to 41.0 dB(8.2–12.4 GHz);After the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 60:40),the strain to failure increases from 18.3±1.9%to 28.1±0.7%(~53.5%),the SE_(R)decreases~22.2%,and the corresponding EMI SE is 43.9 *** MoS_(2)also leads to a more efficient photothermal conversion performance(~45 to~55℃).Additionally,MXene/ANF–MoS_(2)composite films exhibit excellent electric heating performance,quick temperature elevation(15 s),excellent cycle stability(2,2.5,and 3 V),and long-term stability(2520 s).Combining with excellent mechanical performance with high MXene content,electric heating performance,and photothermal conversion performance,EMI shielding ternary MXene/ANF–MoS_(2)composite films could be applied in many industrial *** work broadens how to achieve a balance between mechanical properties and versatility of composites in the case of high-function fillers.

关键词： MXene-MoS_(2) Lubrication toughening EMI shielding Photothermal conversion Electric heating performance

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康复机器人与智能辅助系统的研究进展

自动化学报 2016年第12期42卷 1765-1779页

作者：侯增广赵新刚程龙王启宁王卫群中国科学院自动化研究所复杂系统管理与控制国家重点实验室北京100190 中国科学院脑科学与智能技术卓越创新中心北京100190 中国科学院大学北京100049 中国科学院沈阳自动化研究所机器人学国家重点实验室沈阳110016 北京大学工学院北京大学工程科学与新兴技术高精尖创新中心北京100871

我国正面临日益严重的老龄化问题和数量庞大的残疾人群,康复机器人与智能辅助系统的研究开发和应用有望为解决养老、失能辅助和康复问题提供部分技术手段.康复机器人与智能辅助系统涉及医学、信息、机械、电子、材料、力学等多个学科领... 详细信息

我国正面临日益严重的老龄化问题和数量庞大的残疾人群,康复机器人与智能辅助系统的研究开发和应用有望为解决养老、失能辅助和康复问题提供部分技术手段.康复机器人与智能辅助系统涉及医学、信息、机械、电子、材料、力学等多个学科领域,其研究与开发也面临诸多挑战和困难,本文从"康复机器人及多种康复训练模式"、"智能辅助系统与生机电技术"、"康复与辅助相关的多模态传感与控制方法"、"外骨骼和可穿戴系统、智能假肢与人机安全性"等方面介绍和讨论康复机器人和智能辅助系统的问题和研究进展,以期为未来康复机器人和智能辅助系统的研究与开发提供些许借鉴.

关键词：词康复机器人智能辅助系统外骨骼可穿戴系统智能假肢康复训练多模态传感人机交互生机电技术人机安全性

The complex effects of miR-146a in the pathogenesis of Alzheimer's disease

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Neural Regeneration Research 2025年第5期20卷 1309-1323页

作者： Yunfan long Jiajia Liu Yu wang Haidong Guo Guohong Cui Department of Neurology Shanghai No.9 People’s HospitalShanghai Jiaotong University School of MedicineShanghaiChina Academy of Integrative Medicine Shanghai University of Traditional Chinese MedicineShanghaiChina School of Integrative Medicine Shanghai University of Traditional Chinese MedicineShanghaiChina Department of Neurology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChina

Alzheimer's disease is a neurodegenerative disorder characterized by cognitive dysfunction and behavioral *** plaques formed through the extracellular deposition of amyloid-βproteins,as well as neurofibrillary tangles formed by the intracellular deposition of hyperphosphorylated tau proteins,comprise two typical pathological features of Alzheimer's *** symptomatic treatment,there are no effective therapies for delaying Alzheimer's disease ***(miR)are small,non-coding RNAs that negatively regulate gene expression at the transcriptional and translational levels and play important roles in multiple physiological and pathological ***,miR-146a,a NF-κB-regulated gene,has been extensively implicated in the development of Alzheimer's disease through several *** has demonstrated substantial dysregulation of miR-146a both during the initial phases and throughout the progression of this *** R-146a is believed to reduce amyloid-βdeposition and tau protein hyperphosphorylation through the TLR/IRAK1/TRAF6 pathway;however,there is also evidence supporting that it can promote these processes through many other pathways,thus exacerbating the pathological manifestations of Alzheimer's *** has been widely reported that miR-146a mediates synaptic dysfunction,mitochondrial dysfunction,and neuronal death by targeting m RNAs encoding synapticrelated proteins,mitochondrial-related proteins,and membrane proteins,as well as other *** the impact on glial cells,miR-146a also exhibits differential *** one hand,it causes widespread and sustained inflammation through certain pathways,while on the other hand,it can reverse the polarization of astrocytes and microglia,alleviate neuroinflammation,and promote oligodendrocyte progenitor cell differentiation,thus maintaining the normal function of the myelin sheath and exerting a protective effect on *** this review,we provide a

关键词： Alzheimer's disease amyloid-β glial cells microRNAs miR-146a neuroinflammatory

Summary and clinical application of Zhuang medicine medicated thread moxibustion

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TMR Non-Drug Therapy 2023年第2期6卷 25-30页

作者： Yang-Meng Cao De-Yuan Qin Xiang-Yu Deng Dan-Dan Chen Zong-Xi Sun cheng-long wang Zu-Jie Qin Jin-Ming Huang Guangxi International Zhuang Medicine Hospital Afliliated to Guangxi University of Chinese Medicine Nanning 530201China Graduate School of Nanjing University of Chinese Medicine Nanjing 201029China

Zhuang medicine medicated thread moxibustion is a kind of external therapy with ethnic medicine characteristics that spreads in Guangxi Zhuang *** has a wide range of clinical application and significant curative effect,and can be used to treat diseases such as internal medicine,surgery,dermatology,gynecology,pediatrics,and five sense *** reviewing and combing the literature on the Zhuang medicine medicated thread moxibustion in recent years,this paper summarizes and prospects its clinical application,with a view to further explaining the basic principles and application rules of Zhuang medicine medicated thread moxibustion and digging its clinical value.

关键词： Zhuang medicine medicated thread moxibustion external therapy clinical research

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CO_2注入对煤储层特征影响实验研究

煤炭技术 2017年第5期36卷 47-49页

作者：刘成龙王延斌中国矿业大学(北京)地球科学与测绘工程学院北京100083

用实验方法揭示了高温高压下CO_2注入煤层后发生物理和化学反应对储层特征的影响。CO_2与煤的物理作用会改变煤岩应变和渗透率,随着CO_2注入压力的增大,体积应变增大,围压对煤体应变起抑制作用,围压12 MPa时,煤岩渗透率先降低后增加,围... 详细信息

用实验方法揭示了高温高压下CO_2注入煤层后发生物理和化学反应对储层特征的影响。CO_2与煤的物理作用会改变煤岩应变和渗透率,随着CO_2注入压力的增大,体积应变增大,围压对煤体应变起抑制作用,围压12 MPa时,煤岩渗透率先降低后增加,围压12 MPa和16 MPa时,渗透率降低增加再降低。CO_2与煤中方解石、钾长石产生化学反应导致煤中矿物组成、水质和渗透率发生变化。

关键词： CO2 应变矿物组成水质渗透率