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Brain activity in different brain areas of patients with diabetic vitreous hemorrhage according to voxel-based morphometry

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International Journal of Ophthalmology(English edition) 2025年第2期18卷 258-267页

作者： Li-Jun Ji Jin-Yu Hu Yan-Mei Zeng Qian Ling jie Zou cheng Chen Liang-Qi He Xiao-Yu Wang Hong Wei Xu Chen Yi-Xin Wang Yi Shao Yao Yu Department of Ophthalmology Dahua HospitalShanghai 200237China Department of Endocrine and Metabolic the First Affiliated Hospital of Nanchang UniversityJiangxi Clinical Research Centre for Endocrine and Metabolic DiseaseJiangxi Branch of National Clinical Research Center for metabolic DiseaseNanchang 330006Jiangxi ProvinceChina Department of Ophthalmology the First Affiliated Hospital of Nanchang UniversityNanchang 330006Jiangxi ProvinceChina Ophthalmology Centre of maastricht University Maastricht 6200MSLimburg Provinciethe Netherlands School of optometry and vision science Cardiff UniversityCardiffCF244HQWalesUK Department of Ophthalmology Shanghai General HospitalShanghai Jiao Tong University School of MedicineNational Clinical Research Center for Eye DiseasesShanghai 200080China

AIM:To elucidate the neuropathological mechanisms underlying diabetic vitreous hemorrhage(DVH)and its correlation with clinical ***:Twenty-one individuals with DVH(male/female 12/9;mean age 52.29±11.66y)were selected,alongside 21 appropriately matched controls with diabetes mellitus(DM).Voxel-based morphometry(VBM)techniques were employed to identify aberrant functional regions in the *** operating characteristic(ROC)curves were utilized for classification based on the average VBM values of the two groups,and Pearson correlation analysis was conducted to assess the relationship between average VBM values in distinct brain regions and clinical ***:Relative to the DM controls,DVH patients exhibited reduced VBM values in the right superior temporal pole,the right superior temporal gyrus,the right medial orbital frontal gyrus,and the left superior frontal ***,ROC curve analysis of these four brain regions in DVH patients demonstrated a high degree of accuracy,as indicated by the area under the *** average VBM value in each of these regions exhibited a negative correlation with both the duration of DVH and the score on the Hospital Anxiety and Depression Scale(HADS).CONCLUSION:Pathological alterations in four distinct brain regions are observed in patients with DVH,potentially reflecting neuropathological changes associated with this condition.

关键词： diabetic vitreous hemorrhage voxel-based morphometry Hospital Anxiety and Depression Scale brain areas

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基于加密区块链的双创信息交互技术研究

现代电子技术 2025年第3期48卷 92-96页

作者：程顺达祝婕关胜江程杰窦彤河北大学网络空间安全与计算机学院河北保定071002 河北省中医院信息中心河北石家庄050011

针对共享双创网络平台数据传输过程中普遍存在隐私性差且安全性较低的问题,文中基于区块链和数据加密技术提出一种信息共享算法。该区块链模型的网络层使用了多台局域网计算机节点,并在数据传输时采用混合加密算法DES⁃ECC,从而使安全性... 详细信息

针对共享双创网络平台数据传输过程中普遍存在隐私性差且安全性较低的问题,文中基于区块链和数据加密技术提出一种信息共享算法。该区块链模型的网络层使用了多台局域网计算机节点,并在数据传输时采用混合加密算法DES⁃ECC,从而使安全性与加解密效率相比单一加密算法均有所提升。共识机制还通过使用PBFT算法增强了模型的整体鲁棒性。同时,将算法部署在Hadoop分布式存储架构中,以提高数据传输的速度及吞吐量,且利用Namenode容灾机制进一步保证了数据的安全性。实验测试结果表明,所提加密算法的破译难度较高,而加解密时长仅需约1260 ms,其共识机制吞吐量与时延性能也较为理想,可以实现对双创平台中的大数据进行高效、安全、透明的共享与传输。

关键词：区块链 DES加密 ECC加密拜占庭容错机制 Hadoop平台双创数据共享

Ship detection based on improved SDD algorithm

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Instrumentation 2025年

作者： Hong-cheng Chu Tian-hu Wang Qian-nian Miao Ze-ran Chen Rong Wang Wen-jie Li Tao Huang School of Electrical Information Engineering Jiangsu University of Technology Changzhou High-tech Technology Innovation and Entrepreneurship Service Center Technical Development Department CRRC Nanjing Puzhen Rolling Stock Co. Ltd.

To address the issue of inadequate detection performance for small and mediumsized densely packed vessels in ship target detection, this paper proposes an improved Single Shot Multibox Detector(SSD) model to achieve more accurate detection. The algorithm redesigns the anchor boxes to fit the ship target detection dataset better and integrates the Squeeze-and-Excitation(SE) module into the Visual Geometry Group(VGG)network to enhance the channel features of the input feature maps. Additionally, the network's ability to perceive and represent important features is further enhanced by introducing the Convolutional Block Attention Module(CBAM), which is responsible for channel and spatial attention mechanisms. Finally, the feature pyramid module is employed to fuse six layers of features from the original network, thereby improving the SSD network's capability to detect small and occluded densely packed vessel targets. The experimental results show that the model's target recognition ability for fishing vessels improved from 58.07% to 65.87%; for patrol boats, the ability increased from 94.6% to 96.03%; and for inflatable boats, it rose from 72.08% to 74.93%. The overall mean Average Precision(maP) also increased from the original model's 80.04% to 81.22%. Additionally, by clustering prior boxes, more suitable prior boxes for vessel detection were obtained, enhancing the model's perception capabilities for both large and small vessels.

关键词：

microRNA调控血吸虫生长发育的研究进展

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中国人兽共患病学报 2025年第1期41卷 94-101页

作者：孙成松王毓洁安徽省疾病预防控制中心合肥230601

microRNA(miRNA)是一类大小约22 nt的内源性非编码RNA,其通过与靶基因mRNA序列3′端非翻译区(3′untranslated region,3′UTR)互补结合,促使mRNA降解或抑制翻译,进而调节众多的生理和病理过程。越来越多的证据表明,miRNA在血吸虫生长发... 详细信息

microRNA(miRNA)是一类大小约22 nt的内源性非编码RNA,其通过与靶基因mRNA序列3′端非翻译区(3′untranslated region,3′UTR)互补结合,促使mRNA降解或抑制翻译,进而调节众多的生理和病理过程。越来越多的证据表明,miRNA在血吸虫生长发育以及与宿主间相互作用过程中发挥重要的调控作用。本文着重阐述不同来源miRNA调控血吸虫生长发育的研究进展,为血吸虫生物学与血吸虫病防治研究提供新的思路。

关键词：血吸虫 microRNA 生长发育

Is the Gum Nebula an important interstellar scattering disk of background pulsars?

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Science China(Physics,Mechanics & Astronomy) 2025年第3期Mechanics & Astronomy) .卷 179-190页

作者： Rui Wang Zhen Yan Zhiqiang Shen Ke Jia Lee Yajun Wu Rongbing Zhao Zhipeng Huang Xiaowei Wang jie Liu Shanghai Astronomical Observatory Chinese Academy of Sciences School of Astronomy and Space Sciences University of Chinese Academy of Sciences Key Laboratory of Radio Astronomy and Technology Chinese Academy of Sciences School of Physical Science and Technology Shanghai Tech University Department of Astronomy School of Physics Peking University Kavli Institute for Astronomy and Astrophysics Peking University Department of Physics and Astronomy Hubei University of Education

The Gum Nebula is a faint supernova remnant extending about 40° across the southern sky, potentially affecting tens of background pulsars. Though the view that the Gum Nebula acts as a potential scattering screen for background pulsars has been recurrently mentioned over the past five decades, it has not been directly confirmed. We chose the strong background pulsar PSR B0740-28 as a probe and monitored its diffractive interstellar scintillation（DISS） at 2.25 & 8.60 GHz simultaneously for about two years using the Shanghai Tian ma Radio Telescope（TMRT）. DISS was detected at both frequencies and quantified by two-dimensional autocorrelation analysis. We calculated their scattering spectral index α and found that 9/21 of the observations followed the theoretical predictions, while 4/21 of them clearly showed α malous scattering along the pulsar line of sight, due to the large frequency lever arm and the simultaneous features of our dual-frequency observations. In comparison to the 2.25 GHz observations, scintillation arcs were observed in 10/21 of the secondary spectrum plots for 8.60 GHz observations. Consequently, the highest frequency record for pulsar scintillation arc detection was updated to 8.60 GHz. Our fitting results were the most direct evidence for the view that the Gum Nebula acts as the scattering screen for background pulsars, because both the distance(245-72+69pc) and transverse speed(22.4-4.2+4.1km s-1) of the scintillation screen are comparable with related parameters of the Gum Nebula. Our findings indicated that anisotropic scattering provides a superior explanation for the annual modulation of scintillation arcs than isotropic scattering. Additionally, the orientation of its long axis was also fitted.

关键词： pulsar interstellar scintillation Gum Nebula

Novel Co-Mg-Al-Ti-O catalyst derived from hydrotalcite-like compound for NO storage/decomposition

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Journal of Environmental Sciences 2012年第3期24卷 488-493页

作者： jie cheng Xiaoping Wang Chunyan ma Zhengping Hao Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China

Catalysts of Co1.5Mg1.5/Al0.9Ti0.1O and Co1.5Mg1.5/AlO were successfully prepared by calcinations of corresponding hydrotalcite-like compounds at 800°C for 4 hr. The derived oxides were of spinel phase and a small quantity of Ti substitution did not change the crystal purity. Their catalytic performance for the NO storage/decomposition was investigated. Ti incorporation enhanced the NO decomposition activity while has an opposite effect on the storage capacity of catalyst. In situ FT-IR spectra of the catalysts showed that the final adsorption species on the catalysts was coordinated nitrates/nitrites. In addition, NO storage/decomposition mechanism has been discussed on the basis of these observations.

关键词： NO decomposition storage hydrotalcite-like compounds

Functional ternary salt construction enabling an in-situ Li3N/LiF-enriched interface for ultra-stable all-solid-state lithium metal batteries

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Journal of Energy Chemistry 2025年第2期101卷 68-75页

作者： Hong-Yan Liu Xin-Yu Liu Nan Zhang Peng-Fei Wang Zong-Lin Liu jie Shu Ting-Feng Yi School of materials Science and Engineering Northeastern University Key Laboratory of Dielectric and Electrolyte Functional material Hebei Province School of Resources and Materials Northeastern University at Qinhuangdao Faculty of materials Science and Chemical Engineering and Key Laboratory of Photoelectric Detection materials and Devices of Zhejiang Province Ningbo University

Poly（ethylene oxide）-based polymer all-solid-state lithium metal batteries（ASSLBs） have received widespread attention due to their low cost,good process ability,and high energy ***,the growth of Li dendrites within polymer solid-state electrolytes damages the reversibility of Li anodes and still impedes their widespread *** efficient strategy is to construct a superior solid electrolyte ***,a stable interface enriched with Li3N and LiF is in-situ formed between Li anode and a terna ry salt *** terna ry salt electrolyte is innovatively designed by introducing lithium bis（trifluoromethane sulfonyl）imide（LiTFSI）,lithium bis（fluorosulfonyl）imide（LiFSI）,and LiNO3to poly（ethylene oxide） *** characterization indicates that LiNO3and LiFSI contribute to forming a Li3N-LiF-enriched interface and meanwhile LiTFSI ensures excellent ***,among various Li compound components,Li3N has high ionic conductivity,which is beneficial for reducing overpotential,while LiF has high interfacial energy which can enhance nucleation energy and suppress the formation of Li *** experimental results show that ASSLBs coupled with LiFePO4cathode display extremely excellent cycle stability approximately 2200 cycles at 2 C,with a final and corresponding discharge specific capacity of 96.7 ma h g-1. Additionally,a schematic illustration of the working mechanism for the Li3N-LiF interface is proposed.

关键词： All-solid-state lithium metal batteries In-situ SEI Lithium dendrite PEO (LiTFSI) Solid electrolyte

A mild, configurable, flexible CoNi-LDH(v)/Zn battery based on H-vacancy-induced reversible Zn^(2+) intercalation

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Journal of Energy Chemistry 2025年第1期100卷 498-508页

作者： Xinyue cheng Dingsheng Wu Hao Gao Qingqing Wang Pengfei Lv Sam S.Yoon Qufu Wei Key Laboratory of Eco–textiles Ministry of EducationJiangnan UniversityWuxi 214122JiangsuChina School of Mechanical EngineeringKorea UniversitySeoul 136–713Republic of Korea Received 12 August 2024Revis

Flexible Zn-based batteries have attracted increasing research interest as essential components of wearable energy storage ***,the advancement of flexible aqueous Zn-based batteries based on Co-Ni layered double hydroxide (CoNi-LDH) as the cathode material is hampered by their poor cycling stability and the corrosiveness of alkaline ***,CoNi-LDH nanosheets enriched with H vacancies (CoNi-LDH(v)) were constructed on a flexible carbon cloth (CC) substrate via electrochemical deposition and *** Zn-based battery comprising CoNi-LDH(v)@CC as the cathode exhibited highly reversible conversion reactions and stable operation in 3 M ZnSO4electrolyte (pH=4).The battery delivered an excellent specific capacity (225 ma h g^(-1),0.26 ma h cm^(-2)),acceptable cycling stability(53.9%,900 cycles),and high discharging *** abundant H vacancies served as active sites for the reversible intercalation of Zn^(2+)and the extravasation of NO_(3)-generated channels and space for Zn^(2+)transport and storage,together enabling an excellent Zn^(2+)storage ***,a sandwich-structured solid-state CoNi-LDH(v)@CC//Zn@CC battery was fabricated and was found to exhibit a noteworthy electrochemical performance and mechanical *** a proof of concept,the unencapsulated battery powered a digital watch under various deformation conditions and operated stably for 80 ***,the flexible battery displayed outstanding customizability,maintaining an open-circuit voltage of 1.42 V even after being cut *** proposed engineering strategy contributes to the realization of textiles with truly wearable energy-storage devices.

关键词： CoNi/Zn battery H vacancies Mild aqueous electrolyte Tailorable battery Wearable energy storage device

Tenofovir amibufenamide:A potential alternative for chronic hepatitis B treatment

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World Journal of Gastroenterology 2025年第10期31卷 139-143页

作者： Hai-Nan ma Kai-Sen Cao Yan-Miao Liu cheng Chen Hang Zhang Fu-Shan Tang Department of Clinical Pharmacy Key Laboratory of Basic Pharmacology of Guizhou Province and School of PharmacyZunyi Medical UniversityZunyi 563006Guizhou ProvinceChina Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education Zunyi Medical UniversityZunyi 563006Guizhou ProvinceChina Key Laboratory of Clinical Pharmacy in Zunyi City Zunyi Medical UniversityZunyi 563006Guizhou ProvinceChina

Tenofovir amibufenamide(TMF)is a novel prodrug of tenofovir that demonstrates a promising safety and efficacy profile.A recent study by Peng et al compared TMF with tenofovir alafenamide in the treatment of chronic hepatitis *** findings indicated that both medications offer similar efficacy in terms of viral response and alanine aminotransferase ***,TMF showed potential advantages in lipid management,as it did not significantly affect cholesterol levels,unlike tenofovir *** correspondence highlights the need for further research to evaluate the long-term safety and efficacy of TMF,its impact on cardiovascular risk,and its use in specific patient populations.

关键词： Tenofovir amibufenamide Tenofovir alafenamide Chronic hepatitis B Antiviral efficacy Safety profile Hyperlipidemia