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Pathological changes in the retina and growth associated protein-43 expression following treatment of intracanalicular optic nerve injury via optic canal decompression,dexamethasone or their combination

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Neural Regeneration Research 2010年第10期5卷 752-756页

作者： Xuehong Ju hui cheng Hongguo liu Xiaoshuang Li Xiuyun Li Department of Anatomy Weifang Medical University Weifang 261042 Shandong Province China

BACKGROUND： The main clinical treatments for optic nerve injury are optic canal decompression and systemic administration of hormones, but both treatments have disadvantages. OBJECTIVE： To observe the pathological changes in the retina and growth associated protein-43 （GAP-43） expression, to compare the treatment of optic canal decompression, hormones, and their combination with the intracanalicular optic nerve ***, TIME AND SETTING： A randomized, controlled animal study was performed at the Department of Anatomy, Weifang Medical University, China, from September 2007 to November ***： Dexamethasone （Shandong Huaxin Pharmaceutical, China） and rabbit anti-GAP-43 polyclonal antibody （Boster, China） were ***： All 36 healthy adult rabbits were randomly assigned to control group （n = 4）, simple injury group （n = 20）, and treatment group （n = 12）. Intracanalicular optic nerve injury models were established using the metal cylinder free-fall impact method. The control group was left intact. The treatment group （four rabbits in each subgroup） was treated by optic nerve decompression, dexamethasone treatment （1 mg/kg daily via two intravenous infusions, 1/5 total dose reduction every 3 days, for 14 days）, and simultaneously giving surgery and hormone *** OUTCOME MEASURES： Pathological changes in the retina were determined using hematoxylin-eosin staining. GAP-43 expression was detected using immunohistochemistry in the ***： Retina injury induced obvious pathological changes in the retina. With prolonged time after optic nerve injury, the number of retinal ganglion cells was gradually decreased, and reached the minimum on day 14 （P〈0.01）. All three treatments increased the number of retinal ganglion cells （P〈0.01）, but surgery ＋ hormone treatment was most effective. No GAP-43 cells were present in the normal retinal, but they appeared 3 days after injury, peaked 7 days after injury, and then began to ***： Intra

关键词： optic nerve retina decompression dexamethasone therapy growth associated protein-43 neural regeneration

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Efficient piezo-assisted near-infrared-light-driven Cr（Ⅵ） reduction over Bi2S3 nanowires transformed from ultrathin Bi2WO6 nanosheets

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Rare Metals 2024年第9期43卷 4333-4343页

作者： Qiang Zhang Yuan-Hao cheng Wei liu hui-Nan Che Yan-hui Ao Key Laboratory of Integrated Regulation and Resource Development On Shallow Lakes Ministry of Education College of Environment Hohai University

The utilization of piezo-photocatalytic technol ogy for environmental remediation under full spectrum solar light is promising but still ***,one dimensional Bi2S3nanowires,which can utilize both mechanical energy and near-infrared （NIR） light to remov hexavalent chromium (Cr （VI）) efficiently,were synthe sized by a restrained growth *** reaction rat constants of Cr （VI） reduction in piezo-photocatalyti process under NIR （800–2500 nm） reached 0.334 min-1which were 3.2 and 12.4 times as that of single piezo and photocatalytic *** formation of polarized electri fields and one-dimensional structure allow ultrafast sepa ration of charge carriers,thereby promoting the catalyti ***,due to the strong penetrability o NIR light,the piezo-photocatalysis performance in turbid solutions under NIR light (0.188 min-1) was even com parable to that under visible light (0.186 min-1).Thi study provides a new concept on the development of piezo photocatalytic technology for environmental remediation by utilization of NIR light and natural mechanical energy.

关键词： Bi2S3 nanowires Cr(VI) NIR light Piezo-photocatalysis

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Investigation of stress distribution and damage behavior caused by forced installation of a composite bolted joint with a hole-location error

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Chinese Journal of Aeronautics 2024年第1期37卷 201-217页

作者： Chinan liu Yuan LI Yi cheng An’an ZHAO Kunpeng DU Yue SHI Ximing LI hui cheng School of Mechanical Engineering Northwestern Polytechnical UniversityXi’an 710072China AVIC Xi’an Aircraft Industry Group Company LTD Xi’an 710089China

In this paper,the influence of forced installation caused by a hole-location error on the 3D stress distribution and damage of a composite bolted joint is *** analytical model of stress distributed on composite holes is promoted,in view of non-uniform extrusion caused by forced *** first,non-uniform extrusion of the hole edge caused by forced installation is *** to the contact state,expression of hole deformation is ***,based on Hertz theory,the maximum extrusion load is obtained with help of deformation *** constructing an elastic foundation beam model,3D stress distributed on a hole could be analyzed according to the extrusion ***,stress distribution predicted by the above analytical method is compared with that provided by FE considering composite ***,a forced installation experiment is carried out to analyze the damage distribution of the *** show that a central-symmetrically distributed stress is introduced by the hole-location *** an increment of the error,strength of composite decreases due to extrusion ***,stress presents a concave distribution on the *** the hole-location error exceeding 3%,stress decreases gradually due to failure of *** of holes does not exhibit a centrosymmetric *** damage is mainly distributed on the entrance of the hole at the lower sheet.

关键词： Hole-location error Composite joint Forced installation Stress distribution Damage

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Ti_(3)C_(2)T_(x)MXene wrapped,carbon-coated porous Si sheets for improved lithium storage performance

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Chinese Chemical Letters 2024年第2期35卷 617-621页

作者： hui cheng Yueming liu Zhongling cheng Xianying Wang Na Huang Haijiao Zhang Institute of Nanochemistry and Nanobiology School of Environmental and Chemical EngineeringShanghai UniversityShanghai 200444China Shanghai Key Laboratory of Green Chemistry and Chemical Processes School of Chemistry and Molecular EngineeringEast China Normal UniversityShanghai 200062China Energy Materials Research Center AG Hydrogen Materials & Devices CAS Key Laboratory of Materials for Energy ConversionShanghai Institute of CeramicsChinese Academy of Sciences (SICCAS)Shanghai 200050China

Si-based materials have shown great potential as lithium-ion batteries(LIBs)anodes due to their natural reserves and high theoretical ***,the large volume changes during cycles and poor conductivity of Si lead to rapid capacity decay and poor cycling stability,ultimately limiting their commercial ***,we have skillfully utilized the microporous MCM-22 zeolite as the unique silicon source to produce porous Si(pSi)sheets by a simple magnesiothermic reduction,followed by a carbon coating and further Ti_(3)C_(2)T_(x)MXene assembly,obtaining the ternary pSi@NC@TNSs *** the design,porous Si sheets provide more active sites and shorten Li-ion transport paths for electrochemical *** N-doped carbon(NC)layer serves as a bonding layer to couple pSi and Ti_(3)C_(2)T_(x).The conductive network formed by 2D Ti_(3)C_(2)T_(x)and medium NC layer effectively enhances the overall charge transport of the electrode material,and helps to stabilize the electrode ***,the as-made pSi@NC@TNSs anode delivers an improved lithium storage performance,exhibiting a high reversible capacity of 925 mAh/g at 0.5 A/g after 100 *** present strategy provides an effective way towards high-performance Si-based anodes for LIBs.

关键词： Si anodes Ti_(3)C_(2)Ti_(x)MXene Porous structure Interfacial assembly Lithium-ion batteries

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Overcoming the Na-ion conductivity bottleneck for the cost-competitive chloride solid electrolytes

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Journal of Energy Chemistry 2024年第8期95卷 1-8,I0001页

作者： Lv Hu hui Li Fang Chen Yating liu Jinzhu Wang cheng Ma Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Materials for Energy ConversionDepartment of Materials Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026AnhuiChina National Synchrotron Radiation Laboratory Hefei 230026AnhuiChina

Chloride solid electrolytes possess multiple advantages for the construction of safe,energy-dense allsolid-state sodium batteries,but presently the chlorides with sufficiently high cost-competitiveness for commercialization almost all exhibit low Na-ion conductivities of around 10^(-5)S cm^(-1)or ***,we report a chloride solid electrolyte,Na_(2.7)ZFCl_(5.3)O_(0.7),which reaches a Na-ion conductivity of 2.29×10^(-4)S cm^(-1)at 25℃without involving overly expensive raw materials such as rare-earth chlorides or Na_(2)*** addition to the efficient ion transport,Na_(2.7)ZrCl_(5.3)O_(0.7)also shows an excellent deformability surpassing that of the widely studied Na_(3)PS_(4),Na_(3)SbS_(4),and Na_(2)ZrCl_(6)solid *** combination of these advantages allows the all-solid-state cell based on Na_(2.7)ZrCl_(5.3)O_(0.7)and NaCrO_(2)to realize stable room-temperature cycling at a much higher specific current than those based on other non-viscoelastic chloride solid electrolytes in literature(120 mA g^(-1)vs.12-55 mA g^(-1));after 100 cycles at such a high rate,the Na_(2.7)ZFCl_(5.3)O_(0.7)-based cell can still deliver a discharge capacity of 80 mAh g^(-1)at25℃.

关键词： All-solid-state sodium batteries Ionic conductivities Solid electrolytes Chlorides High voltage stability

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Combined spatial frequency spectroscopy analysis with visible resonance Raman for optical biopsy of human brain metastases of lung cancers

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Journal of Innovative Optical Health Sciences 2019年第2期12卷 93-104页

作者： Yan Zhou cheng-hui liu Yang Pu Binlin Wu Thien An Nguyen Gangge cheng Lixin Zhou Ke Zhu Jun Chen Qingbo Li Robert R.Alfano The Air Force Medical Center PLANo.30 FuchengluHaidian DistrictBeijing 100142P.R.China Department of Physics The City College of the City University of New York Institute of Ultrafast Spectroscopy and Lasers NY 10031USA Physics Department and CSCU Center for Nanotechnology Southern Connecticut State University 501 Crescent Street New HavenCT 06515USA Beijing Cancer Hospital No.52Fuchenglu Haidian DistrictBeijing 100142P.R.China Institute of Physics Chinese Academy of Sciences(CAS)Beijing 100190P.R.China Department of Cardiology Tianjin Medical University General Hospital Tianjin 300052P.R.China Beihang University Xueyuan Road No.37Haidian DistrictBeijing 100191P.R.China

The purpose of this study is to examine optical spatial frequency spectroscopy analysis(SFSA)combined with visible resonance Raman(VRR)spectroscopic method,for thefirst time,to discriminate human brain metastases of lung cancers adenocarcinoma(ADC)and squamous cell carcinoma(SCC)from normal tissues.A total of 31 label-free micrographic images of three type of brain tissues were obtained using a confocal micro-Raman spectroscopic *** spectra of the corresponding samples were synchronously collected using excitation wavelength of 532 nm from the same sites of the *** SFSA method,the difference in the randomness of spatial frequency structures in the micrograph images was analyzed using Gaussian *** standard deviations,calculated from the spatial frequencies of the micrograph images were then analyzed using support vector machine(SVM)*** key VRR biomolecularfingerprints of carotenoids,tryptophan,amide II,lipids and proteins(methylene/methyl groups)were also analyzed using SVM *** three types of brain tissues were identified with high accuracy in the two approaches with high *** results show that SFSA–VRR can potentially be a dual-modal method to provide new criteria for identifying the three types of human brain tissues,which are on-site,real-time and label-free and may improve the accuracy of brain biopsy.

关键词： Spatial frequency spectroscopy analysis(SFSA) visible resonance Raman(VRR) human brain metastatic lung cancer photomicrograph image support vector machine(SVM)

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Localization method of subsynchronous oscillation source based on high-resolution time-frequency distribution image and CNN

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Global Energy Interconnection 2024年第1期7卷 1-13页

作者： hui liu Yundan cheng Yanhui Xu Guanqun Sun Rusi Chen Xiaodong Yu Institute of Electric Power Systems School of Electrical and Electronic EngineeringNorth China Electric Power UniversityBeijing 102206P.R.China Electric Power Research Institute of State Grid Hubei Electric Power Co. Ltd.Wuhan 430077P.R.China Central China Branch of State Grid Corporation of China Wuhan 430077P.R.China

The penetration of new energy sources such as wind power is increasing,which consequently increases the occurrence rate of subsynchronous oscillation ***,existing subsynchronous oscillation source-identification methods primarily analyze fixed-mode oscillations and rarely consider time-varying features,such as frequency drift,caused by the random volatility of wind farms when oscillations *** paper proposes a subsynchronous oscillation sourcelocalization method that involves an enhanced short-time Fourier transform and a convolutional neural network(CNN).First,an enhanced STFT is performed to secure high-resolution time-frequency distribution(TFD)images from the measured data of the generation unit ***,these TFD images are amalgamated to form a subsynchronous oscillation feature map that serves as input to the CNN to train the localization ***,the trained CNN model realizes the online localization of subsynchronous oscillation *** effectiveness and accuracy of the proposed method are validated via multimachine system models simulating forced and natural oscillation events using the Power Systems Computer Aided Design *** results show that the proposed method can localize subsynchronous oscillation sources online while considering unpredictable fluctuations in wind farms,thus providing a foundation for oscillation suppression in practical engineering scenarios.

关键词： Subsynchronous oscillation source localization Synchronous squeezing transform Enhanced short-time Fourier transform Convolutional neural networks

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Remarkable Wear Resistance in a Complex Concentrated Alloy with Nanohierarchical Architecture and Composition Undulation

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Research 2024年第1期2023卷 403-416页

作者： Yushan Geng Wenyuan Chen hui Tan Jun cheng Shengyu Zhu Jun Yang Weimin liu State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000PR China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049PR China Shandong Laboratory of Yantai Advanced Materials and Green Manufacturing Yantai 264000PR China

Sustained wear damages on the sliding surfaces of alloys are generally the culprit responsible for the failure of various mechanical *** by high-entropy effects,here we deliberately deploy nanohierarchical architecture with composition undulation in a Ni50(AlNbTiV)_(50) complex concentrated alloy,which yields ultralow wear rate within the order of 10^(−7) to 10^(−6) mm^(3)/Nm between room temperature and 800℃.Such remarkable wear resistance heretofore represents one of the highest wear resistance reported for the bulk alloys or composites,and originates from the multi-type adaptive friction interface protection governed by intrinsically nano-coupled grains and *** cooperative heterostructure releases gradient frictional stress in stages upon wear at room temperature through the coexistence of multiple deformation pathways while activating a dense nanocrystalline glaze layer upon wear at 800℃ to minimize adhesive and oxidative *** work uncovers a practical avenue for tailoring wear properties with multicomponent heterostructures over a wide temperature range.

关键词： wear alloys friction

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On-demand engineerable visible spectrum by fine control of electrochemical reactions

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National Science Review 2024年第3期11卷 239-249页

作者： Qirong liu Lei liu Yongping Zheng Min Li Baofu Ding Xungang Diao hui-Ming cheng Yongbing Tang Advanced Energy Storage Technology Research Center Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced Technology Chinese Academy of Sciences School of Energy and Power Engineering North University of China School of Resource Environment and Safety EngineeringHunan University of Science and Technology School of Energy and Power Engineering Beihang University Shenzhen Key Laboratory of Energy Materials for Carbon Neutrality Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences

Tunability of optical performance is one of the key technologies for adaptive optoelectronic applications,such as camouflage clothing, displays, and infrared shielding. High-precision spectral tunability is of great importance for some special applications with on-demand adaptability but remains challenging. Here we demonstrate a galvanostatic control strategy to achieve this goal, relying on the finding of the quantitative correlation between optical properties and electrochemical reactions within materials. An electrochromic electro-optical efficiency index is established to optically fingerprint and precisely identify electrochemical redox reactions in the electrochromic device. Consequently, the charge-transfer process during galvanostatic electrochemical reaction can be quantitatively regulated, permitting precise control over the final optical performance and on-demand adaptability of electrochromic devices as evidenced by an ultralow deviation of <3.0%. These findings not only provide opportunities for future adaptive optoelectronic applications with strict demand on precise spectral tunability but also will promote in situ quantitative research in a wide range of spectroelectrochemistry, electrochemical energy storage, electrocatalysis, and material chemistry.

关键词： electrochromics fine control spectral tunability high precision galvanostatic control

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Effects of Different Culture Conditions and Growth States on the Structure and Hemostatic Properties of Coscinodiscus sp.

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Journal of Ocean University of China 2024年第4期23卷 1121-1134页

作者： HE Zheng LI Qinfeng liu Jinfeng hui Guangyan FENG Chao cheng Xiaojie CHEN Xiguang College of Marine Life Science Sanya Oceanographic InstitutionOcean University of ChinaQingdao 266003China Laboratory for Marine Drugs and Bioproducts Qingdao Marine Science and Technology CenterQingdao 266237China Department of Stomatology Qingdao Women and Children’s HospitalQingdao 266034China Department of Stomatology Qingdao Special Servicemen Recuperation Center of PLA NavyQingdao 266071China

As a renewable marine inorganic material,Coscinodiscus *** significant potential in the field of rapid ***,the low yield of Coscinodiscus *** limits the *** this study,two new culture modes were adopted to increase the production of Coscinodiscus sp.,the effect of changes in culture conditions and growth status on the hemostatic activity of diatoms was *** prevent Coscinodiscus *** sinking in culture,the suspension culture mode was realized by adding0.5%*** semi-continuous high nutrient concentration culture mode increased the cell density of Coscinodiscus *** 11000cells mL^(-1)and shorten the culture cycle to 5 *** terms of coagulation activity,the addition of frustules reduced the in vitro coagulation time by half and the activation time of coagulation by 70%.The hemolysis rate and cytotoxicity of frustules harvested in the two culture modes did not change *** results showed that suspension culture mode and high nutrient concentration culture mode only changed the growth state of Coscinodiscus sp.,while the hemostatic performance remained stable.

关键词： diatom culture Coscinodiscus sp frustule hemostatic material hemorrhage control

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