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Indocyanine green retention is a potential prognostic indicator after splenectomy and pericardial devascularization for cirrhotic patients

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Hepatobiliary & Pancreatic Diseases International 2016年第4期15卷 386-390页

作者： Yuan-Biao Zhang Yi Lu Wei-Ding wu cheng-wu Zhang Guo-Liang Shen De-Fei Hong Department of Hepatopancreaticobiliary Surgery&Laparoscopic Minimally hwasive Surgery Zhejiang Provincial People's HospitalHangzhou 310014China

BACKGROUND：Splenectomy and pericardial devascularization（SPD）is an effective treatment of upper gastrointestinal bleeding and hypersplenism in cirrhotic patients with portal *** green retention at 15 minutes（ICGR15）was reported to offer better sensitivity and specificity than the Child-Pugh classification in hepatectomy,but few reports describe ICGR15 in *** present study was to evaluate the prognostic value of ICGR15 for cirrhotic patients with portal hypertension who underwent ***：From January 2012 to January 2015,43 patients with portal hypertension and hypersplenism caused by liver cirrhosis were admitted in our center and received *** ICGR15,Child-Pugh classification,model for end-stage liver disease（MELD）score,and perioperative characteristics were analyzed ***：Preoperative liver function assessment revealed that 34 patients were Child-Pugh class A with ICGR15 of13.6%-43.0%and MELD score of 7-20;8 patients were class B with ICGR15 of 22.8%-40.7%and MELD score of 7-17;1patient was class C with ICGR15 of 39.7%and MELD score of *** optimal ICGR15 threshold for liver function compensation was 31.2%,which offered a sensitivity of 68.4%and a specificity of 70.8%.Univariate analysis showed preoperative ICGR15,MELD score,surgical procedure,intraoperative blood loss,and autologous blood transfusion were significantly different between postoperative liver function compensated and decompensated *** regression analysis revealed that ICGR15 was an independent risk factor of postoperative liver function recovery（P=0.020）.CONCLUSIONS：ICGR15 has outperformed the Child-Pugh classification for assessing liver function in cirrhotic patients with portal ***15 may be a suitable prognostic indicator for cirrhotic patients after SPD.

关键词： indocyanine green liver function test liver cirrhosis splenectomy pericardial devascularization

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Growth of Single-Crystalline Silicon Nanocone Arrays by Plasma Sputtering Reaction Deposition

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Chinese Physics Letters 2017年第2期34卷 60-62页

作者： Zhi-cheng wu Lei-Lei Guan Hui Li Jia-Da wu Jian Sun Ning Xu Department of Optical Science and Engineering Fudan UniversityShanghai 200433

Vertically Migned single-crystalline silicon nanocone （Si-NC） arrays are grown on nickel-coated silicon （100） sub- strates by a novel method i.e., abnormal glow-discharge plasma sputtering reaction deposition. The experimental results show that the inlet CH4/（N2＋H2） ratio has great effects on the morphology of the grown Si-NC arrays. The characterization of the morphology, crystalline structure and composition of the grown Si-NCs indicates that the Si-NCs are grown epitaxially in the vapor-liquid-solid mode. The analyses of optical emission spectra further reveal that the inlet methane can promote the growth of Si-NCs by raising the plasma temperature and enhancing the ion-sputtering. The understanding of the growth mechanism of the Si-NC arrays will be helpful for fabrication of required Si-NC arrays.

关键词： Si NC

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Numerical and experimental studies of hydrodynamic performance of bionic leading-edge tubercle airfoil

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Journal of Hydrodynamics 2019年第6期31卷 1240-1249页

作者： Chun-yu Guo Zuo-tian Zhang Xu-xiang Cao Tie-cheng wu Yu-min Su College of Shipbuilding Engineering Harbin Engineering UniversityHarbin 150001China

This paper studies the bionic tubercle airfoils based on the NACA 0020 prototype airfoil,with 7 models derived from different designs of the span-chord ratios and different tubercle types,along with the option of the wave airfoil surface matching the leading-edge *** water experiments are conducted to test the airfoil profile at a Reynolds number of 3×10^5 and an angle of attack of 0°-30°.Data are recorded by a four-component force balance and the resulted lift,drag,and force moment are *** the analysis of the hydrodynamic characteristics and the flow field characteristics,it is shown that the stall of the tubercle airfoils is milder without an evident stalling angle as compared with that of the normal airfoil *** lift coefficient of the optimized airfoil is significantly elevated at the angle where the NACA 0020 airfoil is in the stall *** lift-drag ratio is also markedly improved at the same *** optimal airfoil profile is finally identified and a further optimization plan is proposed based on the comparison results against the CFD numerical simulation.

关键词： Bionic tubercle computational fluid dynamics stall

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Synthesis of Spirobenzopyrans Carrying a Monoaza-benzo-15-C-5 at the 8-position

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Chinese Chemical Letters 1998年第9期9卷 815-816页

作者： Sheng Hua LIU cheng Tai wu(Department of Chemistry, wuhan University, wuhan 430072) wuhan Univ Dept Chem Wuhan 430072 Peoples R China

Synthesis of spirobenzopyrans bearing monoazacrown at the 8-position is described.

关键词： synthesis spirobenzopyran monoazacrown ester

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Neuroprotective effects of genistein on SH-SY5Y cells overexpressing A53T mutant α-synuclein

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Neural Regeneration Research 2018年第8期13卷 1375-1383页

作者： Huan-cheng wu Qun-Liang Hu Shi-Jun Zhang Yan-Min Wang Zhan-Kui Jin Ling-Fu Lv Sai Zhang Zhen-Lin Liu Hong-Lian wu Ou-Mei cheng Graduate School Tianjin Medical University Tianjin China Tianjin Beichen Hospital Tianjin China Tianjin Key Laboratory of Neurotrauma Repair Institute of Traumatic Brain Injury and Neuroscience Center for Neurology and Neurosurgery of Affiliated Hospital Logistics University of Chinese People's Armed Police Force Tianjin China Department of Clinical Medicine Chongqing Medical University Chongqing China

Genistein, a potent antioxidant compound, protects dopaminergic neurons in a mouse model of Parkinson＇s disease. However, the mecha- nism underlying this action remains unknown. This study investigated human SH-SYSY cells overexpressing the A53T mutant of α-synuclein. Four groups of cells were assayed： a control group （without any treatment）, a genistein group （incubated with 20 μM genistein）, a rote- none group （treated with 50 μM rotenone）, and a rotenone ＋ genistein group （incubated with 20 μM genistein and then treated with 50μM rotenone）. A lactate dehydrogenase release test confirmed the protective effect of genistein, and genistein remarkably reversed mitochondrial oxidative injury caused by rotenone. Western blot assays showed that BCL-2 and Beclin ! levels were markedly higher in the genistein group than in the rotenone group. Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling revealed that genistein inhibited rotenone-induced apoptosis in SH-SYSY cells. Compared with the control group, the expression of NFE2L2 and HMOX1 was significantly increased in the genistein ＋ rotenone group. However, after treatment with estrogen receptor and NFE2L2 channel blockers （ICI-182780 and ML385, respectively）, genistein could not elevate NFE2L2 and HMOX1 expression. ICI-182780 effectively prevented genistein-mediated phosphorylation of NFE2L2 and remarkably suppressed phosphorylation of AKT, a protein downstream of the estrogen receptor. These findings confirm that genistein has neuroprotective effects in a cell model of Parkinson＇s dis- ease. Genistein can reduce oxidative stress damage and cell apoptosis by activating estrogen receptors and NFE2L2 channels.

关键词： nerve regeneration genistein neuroprotection SH-SYSY cells Parkinson's disease rotenone estrogen receptor NFE2L2 A53T a-synuclein oxidative stress neurodegeneration neural regeneration

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A　FACILE　SYNTHESIS　OF　AZACROWN　ETHERS　WITH　INTRAANNULAR　PHENOLIC　GROUPS　IN　A　TWO－PHASE　SYSTEM

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Chinese Chemical Letters 1996年第3期7卷 211-212页

作者： Guo Ping XUE cheng Tai wu(Department of Chemistry, wuhan University,wuhan 430072) wuHAN UNIV DEPT CHEMWUHAN 430072PEOPLES R CHINA

Azacrown ethers with intraannutal phenolic grouch are readily prepared by thereaction of 1, 8- bis (P-tolylsulphonybono) -3, 6-dioxaoctane with 2, 6-bis (bromomethyl) -4-R-anisole (R=CH3, Cl, Br) in a two-phase system...

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Synthesis of Long-Chain SpirobenzopyransBearing a Monoazacrown ether

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Chinese Chemical Letters 1999年第1期10卷 15-16页

作者： Sheng Hua LIU cheng Tat wu(Department of Chemistry, wuhan University, wuhan 430072) wuhan Univ Dept Chem Wuhan 430072 Peoples R China

Two new long-chain spirobenzopyrans and their crowned derivatives were designed and synthesized.

关键词： synthesis long-chain spirobenzopyran monoazacrown ether

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Large scale air pollution prediction with deep convolutional networks

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Science China(Information Sciences) 2021年第9期64卷 116-126页

作者： Gao HUANG Chunjiang GE Tianyu XIONG Shiji SONG Le YANG Baoxian LIU Wenjun YIN cheng wu Department of Automation Tsinghua University Department of Computer Science University of Toronto School of Environment Tsinghua University Beijing Key Laboratory of Airborne Particulate Matter Monitoring Technology Beijing Municipal Environmental Monitoring Center Insights Value Technology CO. LTD.

Although considerable success has been achieved in urban air quality prediction(AQP) with machine learning techniques, accurate and long-term prediction is still challenging. One of the key issues for existing AQP approaches is that air quality monitoring stations are sparsely distributed, typically with around ten monitoring stations per city. As air quality may change abruptly in a local area, it is difficult to perform AQP accurately in areas that are far away from observation points. In addition, due to the large distance between every two monitoring stations, we cannot effectively leverage spatial relations among them to improve the AQP accuracy. In this paper, thanks to the development of low-cost air quality sensors, we are now able to collect a large-scale air quality dataset with 393 deployed air quality monitoring stations in a 120 km × 70 km region, which is more than ten times denser than existing AQP datasets. Further,we present a novel method to handle the data effectively. Specifically, we first convert the observed data from irregularly distributed monitoring stations into a regular image-like pollution map, which can then be processed with advanced deep convolutional networks. The experimental results show that the proposed approach can simultaneously model the temporal and spatial relations in our large-scale densely-observed dataset, leading to significantly improved AQP results.

关键词： air pollution prediction artificial intelligence convolutional neural network

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Crystal Structure of Copper(II) Complex with 3 Hydroxyl 1,5 diazacycloheptane N,N diacetate

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Chinese Journal of Structural Chemistry 1999年第1期18卷 40-42页

作者： LIU Sheng Hua FU En Qin CHEN Liao Rong wu cheng Tai Department of Chemistry Wuhan UniversityWuhan430072 Centre of Analysis and Testing Wuhan UniversityWuhan430072

Crystal structure of copper (II) complex with a new aminocarboxylate ligand, 3 hydroxyl 1, 5 diazacycloheptane N,N  diacetate, C 9H 14 CuN 2O 5·H 2O, M r =311.78 is reported. It crystallizes in orthorhombic Pna2 1 with a=13.340(4), b=8 127(1), c=10.583(4) , V=1147.2(7) 3 , Z=4, D c =1.805g/cm 3, μ =19 287cm -1 (Mo Kα), F (000)=644. The final R and R w are 0.049 and 0.065 for 888 observed reflections with I≥3σ(I ). The result of X ray structure determination shows that the Cu(Ⅱ) forms a planar complex with two oxygen atoms and two nitrogen atoms of the ligand.

关键词： crystal structure aminocarboxylate copper complex

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Tailoring strength and ductility of high-entropy CrMnFeCoNi alloy by adding Al

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Rare Metals 2022年第3期41卷 1015-1021页

作者： Xin Xian Zhi-Hong Zhong Li-Jing Lin Zhi-Xiong Zhu Chang Chen Yu-cheng wu School of Materials Science and Engineering Hefei University of TechnologyHefei 230009China

High-entropy alloys with high strength and acceptable ductility at both room and elevated temperatures for high-temperature structural applications are desired. In this paper, CrMnFeCoNi alloy with outstanding ductility but low strength was selected as baseline alloy to study the formation of hard phase to strengthen this ductile alloy by adding Al into it. The results indicate that there is a phase structure transition from fcc to bcc when adding enough Al into CrMnFeCoNi. The yield strength and hardness increase with the content of Al increasing, due to the formation of hard bcc phase in the ductile CrMnFeCoNi *** CrMnFeCoNiAl alloy with a bcc structure shows a high yield strength and adequate ductility at elevated temperatures. At 400 and 500℃, the yield strength and ductility of CrMnFeCoNiAl alloy are 975.59 MPa and6.39%and 989.48 MPa and 9.15%, respectively. An example of tailoring the strength and ductility of high-entropy alloy is demonstrated in this paper.

关键词： High-entropy alloys Structure transition Strength Ductility

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